Strain Name:
C57BL/6J-MtgxR2139Btlr/Mmmh
Stock Number:
040142-MU
Citation ID:
RRID:MMRRC_040142-MU
Other Names:
R2139 (G1), C57BL/6J-MtgxR2139Btlr
Major Collection:

Gene Information

Lamb3
Name: laminin, beta 3
Synonyms: nicein, 125kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 16780
HGNC: HGNC:6490
Homologene: 191
Slc6a1
Name: solute carrier family 6 (neurotransmitter transporter, GABA), member 1
Synonyms: XT-1, Gabt, GAT-1, Gabt1, Gat1, Xtrp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 232333
Homologene: 2290
Erbb4
Name: erb-b2 receptor tyrosine kinase 4
Synonyms: ErbB4, Her4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 13869
HGNC: HGNC:3432
Homologene: 21084
Dop1b
Name: DOP1 leucine zipper like protein B
Synonyms: 2610510B01Rik, Dopey2, 0610038M01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 70028
VEGA: 16
HGNC: HGNC:1291
Homologene: 21068
Hspa12a
Name: heat shock protein 12A
Synonyms: 1700063D12Rik, Hspa12a, Gm19925
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 73442
VEGA: 19
Homologene: 18422
Fgfr1
Name: fibroblast growth factor receptor 1
Synonyms: Hspy, Flt-2, Eask, Fr1, FGFR-I, Fgfr-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 14182
HGNC: HGNC:3688
Homologene: 69065
Pogz
Name: pogo transposable element with ZNF domain
Synonyms: 9530006B08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229584
Homologene: 9022
Dhcr24
Name: 24-dehydrocholesterol reductase
Synonyms: seladin-1, 5830417J06Rik, 2310076D10Rik, 3-beta-hydroxysterol delta-24 reductase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 74754
HGNC: HGNC:2859
Homologene: 8850
Rap1a
Name: RAS-related protein 1a
Synonyms: Krev-1, Rap1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 109905
HGNC: HGNC:9855
Homologene: 2162
Fbrsl1
Name: fibrosin-like 1
Synonyms: LOC381668, Gm29766, 2410025L10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 381668
Homologene: 45966
Esrrb
Name: estrogen related receptor, beta
Synonyms: Err2, ERRb, ERR2, Estrrb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 26380
HGNC: HGNC:3473
Homologene: 69108
Chaf1a
Name: chromatin assembly factor 1, subunit A (p150)
Synonyms: CAF-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 27221
VEGA: 17
HGNC: HGNC:1910
Homologene: 4003
Chd8
Name: chromodomain helicase DNA binding protein 8
Synonyms: 5830451P18Rik, Duplin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 67772
Homologene: 72405
Kank1
Name: KN motif and ankyrin repeat domains 1
Synonyms: Ankrd15, D330024H06Rik, A930031B09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 107351
Homologene: 17706
Runx2
Name: runt related transcription factor 2
Synonyms: Pebpa2a, SL3-3 enhancer factor 1, polyomavirus enhancer binding factor 2 (PEBP2), Osf2, Cbfa1, PEBP2aA, AML3, PEBP2 alpha A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 12393
Homologene: 68389
Il22ra2
Name: interleukin 22 receptor, alpha 2
Synonyms: Il-22bp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 237310
Homologene: 18657
Olfm4
Name: olfactomedin 4
Synonyms: pPD4, LOC239192, OlfD, GC1, LOC380924, GW112
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 380924
VEGA: 14
Homologene: 4684
Kif13a
Name: kinesin family member 13A
Synonyms: 4930505I07Rik, N-3 kinesin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 16553
VEGA: 13
Homologene: 22589
Cpsf3
Name: cleavage and polyadenylation specificity factor 3
Synonyms: 73 kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 54451
VEGA: 12
HGNC: HGNC:2326
Homologene: 6499
Zfp507
Name: zinc finger protein 507
Synonyms: 1810022O10Rik, A230056M16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 668501
Homologene: 8942
Wdr6
Name: WD repeat domain 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 83669
Homologene: 117682
Gak
Name: cyclin G associated kinase
Synonyms: D130045N16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231580
HGNC: HGNC:4113
Homologene: 3846
Slc4a4
Name: solute carrier family 4 (anion exchanger), member 4
Synonyms: NBC, NBC1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 54403
Homologene: 55776
Lrrc8c
Name: leucine rich repeat containing 8 family, member C
Synonyms: E430036I04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 100604
Homologene: 12997
Washc5
Name: WASH complex subunit 5
Synonyms: strumpellin, E430025E21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 223593
VEGA: 15
Homologene: 8898
Cubn
Name: cubilin (intrinsic factor-cobalamin receptor)
Synonyms: D2Wsu88e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 65969
HGNC: HGNC:2548
Homologene: 37434
Muc4
Name: mucin 4
Synonyms: 4933405I11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 140474
HGNC: HGNC:7514
Homologene: 124469
Nyap2
Name: neuronal tyrosine-phophorylated phosphoinositide 3-kinase adaptor 2
Synonyms: 9430031J16Rik, Jr6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 241134
Homologene: 18239
Pcdhac1
Name: protocadherin alpha subfamily C, 1
Synonyms: CNRc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 353236
HGNC: HGNC:8676
Homologene: 49561
Pkhd1l1
Name: polycystic kidney and hepatic disease 1-like 1
Synonyms: PKHDL1, fibrocystin L, D86 mRNA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 192190
Homologene: 16332
Vwa7
Name: von Willebrand factor A domain containing 7
Synonyms: D17H6S56E-3, G7c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 27762
Homologene: 11895
Nav3
Name: neuron navigator 3
Synonyms: 9630020C08Rik, Pomfil1p, 4732483H20Rik, unc53H3, steerin 3, POMFIL1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 260315
Homologene: 56688
Unc80
Name: unc-80, NALCN activator
Synonyms: C030018G13Rik, C230061B10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 329178
Homologene: 122243
Fbxo24
Name: F-box protein 24
Synonyms: 4933422D21Rik, Fbx24
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 71176
Homologene: 14131
Neb
Name: nebulin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 17996
HGNC: HGNC:7720
Homologene: 136285
Gm11639
Name: predicted gene 11639
Synonyms: Efcab15, Gm11639
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 105242472
Il1f8
Name: interleukin 1 family, member 8
Synonyms: 2310043N20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 69677
Homologene: 18278
Ac127374.1
Name: Uncharacterized protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
Egr2
Name: early growth response 2
Synonyms: Egr-2, Krox20, NGF1-B, Krox-20, Zfp-25
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 13654
HGNC: HGNC:3239
Homologene: 20123
Ltbp2
Name: latent transforming growth factor beta binding protein 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 16997
HGNC: HGNC:6715
Homologene: 369
Krt86
Name: keratin 86
Synonyms: Krt2-10, MHb4, Krt2-11, Khb4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 16679
VEGA: 15
HGNC: HGNC:6463
Homologene: 1717
Syna
Name: syncytin a
Synonyms: syncytin-A, Gm52
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 214292
Homologene: 86751
Lgi4
Name: leucine-rich repeat LGI family, member 4
Synonyms: clp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 243914
Homologene: 16408
Cacna1b
Name: calcium channel, voltage-dependent, N type, alpha 1B subunit
Synonyms: Cchn1a, Cav2.2, alpha(1B)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 12287
HGNC: HGNC:1389
Homologene: 20184
Vmn2r56
Name: vomeronasal 2, receptor 56
Synonyms: EG629079
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 629079
Homologene: 104040
Krt81
Name: keratin 81
Synonyms: Krt2-19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 64818
VEGA: 15
HGNC: HGNC:6458
Homologene: 55645
Olfr616
Name: olfactory receptor 616
Synonyms: GA_x6K02T2PBJ9-6289676-6288723, MOR19-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 259103
Homologene: 64957
St18
Name: suppression of tumorigenicity 18
Synonyms: Nzf3, Myt3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 240690
Homologene: 8792
4931429L15Rik
Name: RIKEN cDNA 4931429L15 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 74361
Homologene: 86847
Greb1l
Name: growth regulation by estrogen in breast cancer-like
Synonyms: mKIAA4095, AK220484
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 381157
Homologene: 73393
Mroh5
Name: maestro heat-like repeat family member 5
Synonyms: LOC268816, Gm628
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 268816
Myom1
Name: myomesin 1
Synonyms: skelemin, D430047A17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 17929
VEGA: 17
HGNC: HGNC:7613
Homologene: 31196
Trim7
Name: tripartite motif-containing 7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 94089
Homologene: 14113
Dlg5
Name: discs large MAGUK scaffold protein 5
Synonyms: 4933429D20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 71228
HGNC: HGNC:2904
Homologene: 3486
Hapln4
Name: hyaluronan and proteoglycan link protein 4
Synonyms: Bral2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 330790
Homologene: 11304
Cyp4f39
Name: cytochrome P450, family 4, subfamily f, polypeptide 39
Synonyms: 4732474A20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 320997
VEGA: 17
Homologene: 69814
Pgbd1
Name: piggyBac transposable element derived 1
Synonyms: 4921509E05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 319207
Homologene: 130030
Rab13
Name: RAB13, member RAS oncogene family
Synonyms: 0610007N03Rik, B230212B15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 68328
HGNC: HGNC:9762
Homologene: 113882
Tgm1
Name: transglutaminase 1, K polypeptide
Synonyms: protein-glutamine-gamma-glutamyltransferase, K polypeptide, TGase1, 2310004J08Rik, TG K, TGase 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 21816
VEGA: 14
Homologene: 306
Olfr1199
Name: olfactory receptor 1199
Synonyms: MOR230-8, GA_x6K02T2Q125-50231574-50230642
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258450
Homologene: 128092
Myrf
Name: myelin regulatory factor
Synonyms: LOC386531, LOC225908, Gm98
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 225908
HGNC: HGNC:1181
Homologene: 32167
Vmn1r74
Name: vomeronasal 1 receptor 74
Synonyms: V1rg5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 171240
Homologene: 110796
Bfsp2
Name: beaded filament structural protein 2, phakinin
Synonyms: CP49
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 107993
HGNC: HGNC:1041
Homologene: 20791
Tle6
Name: transducin-like enhancer of split 6
Synonyms: Grg6, 1810057E06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 114606
Homologene: 11701
AC148991.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
Hoxc10
Name: homeobox C10
Synonyms: Hox-3.6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 209448
HGNC: HGNC:5122
Homologene: 9680
Txndc16
Name: thioredoxin domain containing 16
Synonyms: 5730420B22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 70561
Homologene: 18197
Col23a1
Name: collagen, type XXIII, alpha 1
Synonyms: 2810458L13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 237759
Homologene: 72101
Gpr61
Name: G protein-coupled receptor 61
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229714
Homologene: 12910
Elovl1
Name: elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1
Synonyms: Ssc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 54325
Homologene: 41322
Marc1
Name: mitochondrial amidoxime reducing component 1
Synonyms: 1300013F15Rik, Mosc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 66112
Homologene: 129604
Tmem181a
Name: transmembrane protein 181A
Synonyms: Gpr178, Tmem181, 5930418K15Rik, C76977
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 77106
Homologene: 44787
Olfr419
Name: olfactory receptor 419
Synonyms: GA_x6K02T2P20D-20891507-20892448, MOR267-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 258710
Homologene: 72017
Mbd3l2
Name: methyl-CpG binding domain protein 3-like 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 234988
VEGA: 9
Homologene: 44896
Olfr283
Name: olfactory receptor 283
Synonyms: MOR160-1, GA_x6K02T2NBG7-5351896-5352825
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 259038
Homologene: 64944
Dnaja4
Name: DnaJ heat shock protein family (Hsp40) member A4
Synonyms: 1110021L12Rik, Hsj4, Dj4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 58233
Homologene: 23110
AC188608.2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to G, chromosome 1 at 6,810,615 bp
  • C to T, chromosome 1 at 66,521,581 bp
  • A to G, chromosome 1 at 68,346,629 bp
  • A to G, chromosome 1 at 81,241,268 bp
  • A to T, chromosome 1 at 174,250,736 bp
  • G to A, chromosome 1 at 184,795,435 bp
  • T to A, chromosome 1 at 193,331,420 bp
  • T to C, chromosome 2 at 13,336,167 bp
  • A to G, chromosome 2 at 24,154,660 bp
  • A to C, chromosome 2 at 24,679,473 bp
  • T to C, chromosome 2 at 52,212,588 bp
  • T to A, chromosome 2 at 88,756,093 bp
  • T to C, chromosome 3 at 90,223,878 bp
  • T to C, chromosome 3 at 94,871,007 bp
  • T to C, chromosome 3 at 105,739,540 bp
  • A to T, chromosome 3 at 108,150,761 bp
  • G to T, chromosome 4 at 106,572,302 bp
  • A to G, chromosome 4 at 118,431,106 bp
  • A to T, chromosome 5 at 89,046,264 bp
  • T to G, chromosome 5 at 105,606,692 bp
  • C to T, chromosome 5 at 108,606,877 bp
  • A to T, chromosome 5 at 110,396,086 bp
  • G to T, chromosome 5 at 134,559,252 bp
  • A to T, chromosome 5 at 137,613,065 bp
  • T to C, chromosome 6 at 114,304,061 bp
  • A to G, chromosome 7 at 11,847,316 bp
  • T to A, chromosome 7 at 12,712,963 bp
  • A to T, chromosome 7 at 31,063,123 bp
  • A to G, chromosome 7 at 35,793,723 bp
  • A to T, chromosome 7 at 103,564,754 bp
  • T to G, chromosome 8 at 25,570,866 bp
  • A to T, chromosome 8 at 31,737,460 bp
  • T to C, chromosome 8 at 70,088,138 bp
  • A to T, chromosome 9 at 18,444,958 bp
  • A to T, chromosome 9 at 46,304,295 bp
  • A to T, chromosome 9 at 54,709,222 bp
  • T to C, chromosome 9 at 103,449,875 bp
  • T to C, chromosome 9 at 108,574,123 bp
  • T to A, chromosome 10 at 19,632,870 bp
  • T to A, chromosome 10 at 67,540,872 bp
  • G to T, chromosome 10 at 81,594,034 bp
  • T to C, chromosome 10 at 109,853,135 bp
  • T to C, chromosome 11 at 48,838,894 bp
  • T to C, chromosome 11 at 51,574,034 bp
  • C to T, chromosome 11 at 104,751,911 bp
  • G to A, chromosome 12 at 21,302,348 bp
  • T to C, chromosome 12 at 84,815,979 bp
  • T to C, chromosome 12 at 86,421,966 bp
  • A to G, chromosome 13 at 21,423,020 bp
  • T to C, chromosome 13 at 46,752,469 bp
  • T to C, chromosome 14 at 24,170,544 bp
  • A to T, chromosome 14 at 45,172,589 bp
  • G to A, chromosome 14 at 52,236,971 bp
  • A to G, chromosome 14 at 55,709,543 bp
  • T to C, chromosome 14 at 80,014,315 bp
  • A to C, chromosome 15 at 44,529,818 bp
  • G to A, chromosome 15 at 59,350,142 bp
  • T to A, chromosome 15 at 73,790,091 bp
  • T to C, chromosome 15 at 98,378,264 bp
  • A to G, chromosome 15 at 101,460,118 bp
  • A to T, chromosome 15 at 101,473,758 bp
  • A to T, chromosome 15 at 102,967,477 bp
  • T to A, chromosome 16 at 32,761,225 bp
  • T to C, chromosome 16 at 93,771,007 bp
  • T to C, chromosome 17 at 6,298,206 bp
  • A to G, chromosome 17 at 32,491,189 bp
  • T to G, chromosome 17 at 35,023,430 bp
  • T to A, chromosome 17 at 39,953,384 bp
  • C to T, chromosome 17 at 44,814,307 bp
  • T to C, chromosome 17 at 56,065,226 bp
  • T to C, chromosome 17 at 71,101,219 bp
  • A to C, chromosome 18 at 10,555,011 bp
  • T to G, chromosome 18 at 37,146,086 bp
  • C to G, chromosome 19 at 10,216,467 bp
  • A to T, chromosome 19 at 10,997,331 bp
  • G to A, chromosome 19 at 25,411,753 bp
  • A to G, chromosome 19 at 58,799,482 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R2139 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040142-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.