Strain Name:
C57BL/6J-MtgxR2421Btlr/Mmmh
Stock Number:
040383-MU
Citation ID:
RRID:MMRRC_040383-MU
Other Names:
R2421 (G1), C57BL/6J-MtgxR2421Btlr
Major Collection:

Gene Information

Vangl2
Name: VANGL planar cell polarity 2
Synonyms: Lpp1, C530001F03Rik, skam17Jus, Ltap, strabismus, loop-tail, ska17, Lootl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 93840
Homologene: 62161
Adcy10
Name: adenylate cyclase 10
Synonyms: soluble adenylyl cyclase, sAC, 4930431D04Rik, Sacy
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 271639
Homologene: 10188
Arhgap39
Name: Rho GTPase activating protein 39
Synonyms: D15Wsu169e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223666
Homologene: 27825
Pef1
Name: penta-EF hand domain containing 1
Synonyms: 2600002E23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 67898
Homologene: 56569
Arhgef12
Name: Rho guanine nucleotide exchange factor (GEF) 12
Synonyms: LARG, 2310014B11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 69632
VEGA: 9
Homologene: 9088
Dnajc21
Name: DnaJ heat shock protein family (Hsp40) member C21
Synonyms: 9930116P15Rik, 4930461P20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 78244
Homologene: 6752
Spred1
Name: sprouty protein with EVH-1 domain 1, related sequence
Synonyms: Spred-1, 5730461F13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 114715
Homologene: 24919
Gart
Name: phosphoribosylglycinamide formyltransferase
Synonyms: Gaps, Prgs
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 14450
HGNC: HGNC:4163
Homologene: 637
Washc4
Name: WASH complex subunit 4
Synonyms: A230046K03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 319277
VEGA: 10
Homologene: 123926
Phf20l1
Name: PHD finger protein 20-like 1
Synonyms: CGI-72, E130113K22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239510
VEGA: 15
Homologene: 9341
Birc6
Name: baculoviral IAP repeat-containing 6
Synonyms: apollon, Bruce, A430032G04Rik, D630005A10Rik, A430040A19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 12211
Homologene: 7248
Wdr48
Name: WD repeat domain 48
Synonyms: 8430408H12Rik, Uaf1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 67561
VEGA: 9
Homologene: 10830
Tyw1
Name: tRNA-yW synthesizing protein 1 homolog (S. cerevisiae)
Synonyms: Rsafd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100929
Homologene: 7068
Xpo4
Name: exportin 4
Synonyms: B430309A01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 57258
Homologene: 10733
Aspm
Name: abnormal spindle microtubule assembly
Synonyms: Sha1, Aspm, D330028K02Rik, MCPH5, Calmbp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12316
Homologene: 7650
Ankfy1
Name: ankyrin repeat and FYVE domain containing 1
Synonyms: Ankhzn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 11736
Homologene: 9491
Atxn2
Name: ataxin 2
Synonyms: ATX2, 9630045M23Rik, Sca2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 20239
Homologene: 2234
Ccdc18
Name: coiled-coil domain containing 18
Synonyms: 1700021E15Rik, 4932411G06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 73254
Homologene: 35455
Mdn1
Name: midasin AAA ATPase 1
Synonyms: LOC213784, 4833432B22Rik, D4Abb1e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100019
Homologene: 39689
Apaf1
Name: apoptotic peptidase activating factor 1
Synonyms: Apaf1l, 6230400I06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 11783
HGNC: HGNC:576
Homologene: 7626
Ank3
Name: ankyrin 3, epithelial
Synonyms: Ank-3, Ankyrin-3, AnkG, 2900054D09Rik, Ankyrin-G
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 11735
HGNC: HGNC:494
Homologene: 56908
Syt9
Name: synaptotagmin IX
Synonyms: Sytv
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 60510
Homologene: 11062
Dcp1b
Name: decapping mRNA 1B
Synonyms: B930050E02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 319618
Homologene: 51881
Ryr2
Name: ryanodine receptor 2, cardiac
Synonyms: 9330127I20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 20191
VEGA: 13
Homologene: 37423
Uba6
Name: ubiquitin-like modifier activating enzyme 6
Synonyms: 5730469D23Rik, Ube1l2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231380
Homologene: 10080
Atp13a3
Name: ATPase type 13A3
Synonyms: LOC224088, LOC224087, LOC385637
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 224088
Homologene: 23455
Ppp4r3a
Name: protein phosphatase 4 regulatory subunit 3A
Synonyms: 1110034C04Rik, Smek1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 68734
VEGA: 12
Homologene: 69510
Lyn
Name: LYN proto-oncogene, Src family tyrosine kinase
Synonyms: Hck-2, Yamaguchi sarcoma viral (v-yes-1) oncogene homolog
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 17096
HGNC: HGNC:6735
Homologene: 55649
Plekhg1
Name: pleckstrin homology domain containing, family G (with RhoGef domain) member 1
Synonyms: D10Ertd733e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 213783
Homologene: 18897
Csgalnact1
Name: chondroitin sulfate N-acetylgalactosaminyltransferase 1
Synonyms: CSGalNAcT-1, 4732435N03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234356
Homologene: 23099
Ms4a4b
Name: membrane-spanning 4-domains, subfamily A, member 4B
Synonyms: Chandra, Ly116
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 60361
Homologene: 113790
Lama1
Name: laminin, alpha 1
Synonyms: Lama
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 16772
VEGA: 17
HGNC: HGNC:6481
Homologene: 21146
Psmd2
Name: proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
Synonyms: TEG-190, Tex190, 9430095H01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 21762
HGNC: HGNC:9559
Homologene: 2101
Zfp644
Name: zinc finger protein 644
Synonyms: 1110068L01Rik, BM-005, Zep-2, D5Ertd689e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 52397
Homologene: 12971
Pwp2
Name: PWP2 periodic tryptophan protein homolog (yeast)
Synonyms: Pwp2, 6530411D08Rik, Pwp2h
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 110816
VEGA: 10
HGNC: HGNC:9711
Homologene: 3702
Synrg
Name: synergin, gamma
Synonyms: L71-5, Ap1gbp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217030
HGNC: HGNC:557
Homologene: 105680
Coq10b
Name: coenzyme Q10B
Synonyms: 1700030I21Rik, 9530077A17Rik, 1500041J02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 67876
Homologene: 6916
Gpr107
Name: G protein-coupled receptor 107
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 277463
Homologene: 81077
Vps13a
Name: vacuolar protein sorting 13A
Synonyms: 4930516E05Rik, D330038K10Rik, 4930543C13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 271564
VEGA: 19
HGNC: HGNC:1908
Homologene: 22068
Tmub2
Name: transmembrane and ubiquitin-like domain containing 2
Synonyms: 2010008E23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 72053
Homologene: 18581
Col4a3
Name: collagen, type IV, alpha 3
Synonyms: alpha3(IV), tumstatin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12828
HGNC: HGNC:2204
Homologene: 68033
Prlr
Name: prolactin receptor
Synonyms: Pr-1, Prlr-rs1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 19116
HGNC: HGNC:9446
Homologene: 733
Scn7a
Name: sodium channel, voltage-gated, type VII, alpha
Synonyms: Nav2.3, NaG, Nav2, 1110034K09Rik, Scn6a, Nax
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20272
Homologene: 55706
Unc13c
Name: unc-13 homolog C
Synonyms: Munc13-3, Unc13h3, D9Ertd414e, 1500037O19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 208898
Homologene: 45443
Cracdl
Name: capping protein inhibiting regulator of actin like
Synonyms: 2010300C02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 72097
Homologene: 19208
Lrp1b
Name: low density lipoprotein-related protein 1B
Synonyms: 9630004P12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 94217
HGNC: HGNC:6693
Homologene: 56810
Camk2d
Name: calcium/calmodulin-dependent protein kinase II, delta
Synonyms: CaMK II, 2810011D23Rik, 8030469K03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 108058
HGNC: HGNC:1462
Homologene: 55561
Ppfia4
Name: protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
Synonyms: 1110008G13Rik, LOC100042382, Liprin-alpha4, Gm3812
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 68507
HGNC: HGNC:9248
Homologene: 66200
Adamts3
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 3
Synonyms: 6330442E02Rik, 1100001H14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 330119
HGNC: HGNC:219
Homologene: 8596
Ttc23l
Name: tetratricopeptide repeat domain 23-like
Synonyms: 4930401A09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 75777
Homologene: 44907
Ptprt
Name: protein tyrosine phosphatase, receptor type, T
Synonyms: RPTPrho
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 19281
HGNC: HGNC:9682
Homologene: 56924
Adgre4
Name: adhesion G protein-coupled receptor E4
Synonyms: EGF-TM7, D17Ertd479e, FIRE, Gpr127, Emr4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 52614
VEGA: 17
Homologene: 64640
Or10d5
Name: olfactory receptor family 10 subfamily D member 5
Synonyms: GA_x6K02T2PVTD-33651220-33650288, MOR224-2, Olfr975
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258825
VEGA: 9
Homologene: 27275
Krt78
Name: keratin 78
Synonyms: 2310030B04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 332131
VEGA: 15
Homologene: 65261
Krt13
Name: keratin 13
Synonyms: Krt-1.13, K13, Krt1-13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 16663
HGNC: HGNC:6415
Homologene: 40740
Vmn2r105
Name: vomeronasal 2, receptor 105
Synonyms: EG627743
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 627743
Homologene: 129680
Alpk2
Name: alpha-kinase 2
Synonyms: Hak
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 225638
Homologene: 50475
Gm6327
Name: predicted gene 6327
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Zswim8
Name: zinc finger SWIM-type containing 8
Synonyms: 4832404P21Rik, 2310021P13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 268721
VEGA: 14
Homologene: 34313
Wdhd1
Name: WD repeat and HMG-box DNA binding protein 1
Synonyms: AND-1, D630024B06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 218973
Homologene: 56019
Tfb2m
Name: transcription factor B2, mitochondrial
Synonyms: Hkp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 15278
Homologene: 7362
Rgs6
Name: regulator of G-protein signaling 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 50779
Homologene: 68385
Zfp821
Name: zinc finger protein 821
Synonyms: 4930566A11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 75871
Homologene: 32345
Cpz
Name: carboxypeptidase Z
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 242939
HGNC: HGNC:2333
Homologene: 2709
AC091683.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Vmn2r12
Name: vomeronasal 2, receptor 12
Synonyms: Gm6769
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 627569
Homologene: 129606
Taar7a
Name: trace amine-associated receptor 7A
Synonyms: LOC215856, Taar7a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 215856
Homologene: 110833
Or4c114
Name: olfactory receptor family 4 subfamily C member 114
Synonyms: GA_x6K02T2Q125-50555603-50554668, MOR233-6, Olfr1219
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258901
Homologene: 27292
Pnliprp1
Name: pancreatic lipase related protein 1
Synonyms: Plrp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 18946
VEGA: 19
HGNC: HGNC:9156
Homologene: 21253
Creb3l3
Name: cAMP responsive element binding protein 3-like 3
Synonyms: CREB-H, D10Bur1e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 208677
Homologene: 13080
Dtd2
Name: D-tyrosyl-tRNA deacylase 2
Synonyms: 4930578F06Rik, B830049N13Rik, 6530401N04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 328092
Homologene: 12634
Or5k8
Name: olfactory receptor family 5 subfamily K member 8
Synonyms: GA_x54KRFPKG5P-55026345-55025418, GA_x54KRFPKG5P-54993816-54992890, MOR184-10P, MOR184-1, Olfr174, Olfr175, Olfr175-ps1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 259004
Homologene: 17461
H2-M10.5
Name: histocompatibility 2, M region locus 10.5
Synonyms: 6.9H
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224761
Homologene: 117973
Antxrl
Name: anthrax toxin receptor-like
Synonyms: 1700112N15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 239029
VEGA: 14
Homologene: 52111
Abraxas1
Name: BRCA1 A complex subunit
Synonyms: 5630400M01Rik, 3830405G04Rik, Ccdc98, Fam175a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 70681
Homologene: 16376
Or13a1
Name: olfactory receptor family 13 subfamily A member 1
Synonyms: GA_x54KRFPKN04-58127726-58128655, MOR253-9, Olfr211
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 258914
Homologene: 17434
Ccdc122
Name: coiled-coil domain containing 122
Synonyms: 4933415L06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 108811
Homologene: 51651
Ly6g6e
Name: lymphocyte antigen 6 complex, locus G6E
Synonyms: 2310011I02Rik, G6e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 70274
Homologene: 41553
Pttg1ip2
Name: PTTG1IP family member 2
Synonyms: LOC381716, 1700015F17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 381716
Homologene: 136447
Ndufaf1
Name: NADH:ubiquinone oxidoreductase complex assembly factor 1
Synonyms: CGI-65, CIA30, 2410001M24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 69702
Homologene: 32289
Ccdc137
Name: coiled-coil domain containing 137
Synonyms: 3110023B02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 67291
Homologene: 34992
Gm17421
Name: predicted gene, 17421
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Rbm12b2
Name: RNA binding motif protein 12 B2
Synonyms: C430048L16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 77604
Homologene: 28658
Or5k15
Name: olfactory receptor family 5 subfamily J member 15
Synonyms: GA_x54KRFPKG5P-55108059-55107100, MOR184-6, Olfr178
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 258999
Homologene: 79412
Mmaa
Name: methylmalonic aciduria (cobalamin deficiency) type A
Synonyms: 2810018E08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 109136
Homologene: 14586
Smc1a
Name: structural maintenance of chromosomes 1A
Synonyms: Smc1, SB1.8, SMCB, 5830426I24Rik, Smc1alpha, Smc1l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 24061
Homologene: 4597
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to A, chromosome 1 at 37,613,475 bp
  • G to A, chromosome 1 at 55,052,977 bp
  • G to A, chromosome 1 at 82,670,275 bp
  • T to C, chromosome 1 at 134,327,400 bp
  • G to A, chromosome 1 at 139,488,487 bp
  • T to A, chromosome 1 at 165,558,597 bp
  • T to C, chromosome 1 at 172,007,959 bp
  • C to A, chromosome 1 at 179,533,666 bp
  • G to A, chromosome 2 at 31,185,529 bp
  • T to C, chromosome 2 at 40,882,133 bp
  • A to T, chromosome 2 at 66,726,302 bp
  • T to C, chromosome 2 at 89,074,992 bp
  • T to C, chromosome 2 at 117,165,010 bp
  • T to C, chromosome 2 at 119,655,737 bp
  • T to A, chromosome 2 at 162,278,040 bp
  • A to G, chromosome 3 at 126,780,415 bp
  • C to T, chromosome 4 at 3,748,787 bp
  • T to C, chromosome 4 at 12,095,127 bp
  • T to A, chromosome 4 at 32,723,621 bp
  • C to A, chromosome 4 at 130,127,317 bp
  • T to C, chromosome 5 at 5,455,912 bp
  • G to A, chromosome 5 at 35,512,399 bp
  • A to G, chromosome 5 at 86,132,616 bp
  • A to G, chromosome 5 at 89,683,175 bp
  • C to T, chromosome 5 at 100,812,174 bp
  • A to G, chromosome 5 at 106,637,244 bp
  • A to C, chromosome 5 at 108,228,588 bp
  • A to G, chromosome 5 at 109,086,532 bp
  • A to T, chromosome 5 at 121,802,079 bp
  • A to T, chromosome 5 at 130,269,260 bp
  • T to A, chromosome 6 at 116,493,713 bp
  • A to G, chromosome 6 at 119,215,266 bp
  • G to A, chromosome 7 at 107,436,781 bp
  • A to T, chromosome 8 at 68,461,508 bp
  • T to A, chromosome 8 at 79,281,432 bp
  • T to A, chromosome 8 at 109,709,533 bp
  • A to G, chromosome 9 at 39,950,528 bp
  • A to T, chromosome 9 at 43,001,006 bp
  • T to C, chromosome 9 at 73,931,547 bp
  • T to A, chromosome 9 at 119,902,404 bp
  • G to A, chromosome 10 at 3,958,048 bp
  • T to C, chromosome 10 at 23,992,517 bp
  • T to C, chromosome 10 at 69,982,204 bp
  • A to C, chromosome 10 at 78,173,469 bp
  • T to C, chromosome 10 at 81,091,818 bp
  • T to A, chromosome 10 at 83,579,521 bp
  • A to T, chromosome 10 at 91,020,723 bp
  • T to A, chromosome 11 at 72,755,896 bp
  • A to G, chromosome 11 at 84,009,224 bp
  • A to T, chromosome 11 at 100,120,051 bp
  • T to A, chromosome 11 at 102,287,755 bp
  • G to A, chromosome 11 at 120,462,264 bp
  • A to G, chromosome 12 at 51,999,855 bp
  • C to A, chromosome 12 at 83,116,283 bp
  • A to G, chromosome 12 at 101,042,653 bp
  • T to A, chromosome 12 at 113,369,487 bp
  • T to G, chromosome 13 at 11,591,237 bp
  • T to C, chromosome 13 at 49,900,663 bp
  • A to G, chromosome 14 at 20,719,457 bp
  • A to G, chromosome 14 at 34,071,689 bp
  • G to A, chromosome 14 at 47,258,584 bp
  • T to C, chromosome 14 at 57,629,503 bp
  • T to C, chromosome 14 at 77,091,663 bp
  • T to A, chromosome 15 at 10,319,257 bp
  • A to G, chromosome 15 at 10,461,935 bp
  • G to A, chromosome 15 at 10,537,566 bp
  • A to G, chromosome 15 at 66,613,281 bp
  • T to A, chromosome 15 at 76,725,146 bp
  • T to C, chromosome 15 at 101,947,264 bp
  • T to C, chromosome 16 at 12,760,094 bp
  • T to A, chromosome 16 at 20,660,106 bp
  • T to C, chromosome 16 at 30,349,825 bp
  • T to C, chromosome 16 at 58,824,346 bp
  • T to C, chromosome 16 at 58,889,965 bp
  • A to G, chromosome 16 at 91,643,040 bp
  • T to A, chromosome 17 at 20,227,835 bp
  • G to A, chromosome 17 at 35,078,146 bp
  • A to G, chromosome 17 at 36,774,999 bp
  • A to G, chromosome 17 at 55,778,872 bp
  • A to T, chromosome 17 at 67,750,553 bp
  • T to A, chromosome 17 at 74,660,614 bp
  • T to C, chromosome 18 at 65,306,616 bp
  • A to G, chromosome 19 at 11,454,697 bp
  • T to G, chromosome 19 at 16,759,671 bp
  • T to A, chromosome 19 at 58,744,085 bp
  • A to G, chromosome X at 152,047,975 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R2421 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
040383-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.