Strain Name:
C57BL/6J-MtgxR2570Btlr/Mmmh
Stock Number:
040428-MU
Citation ID:
RRID:MMRRC_040428-MU
Other Names:
R2570 (G1), C57BL/6J-MtgxR2570Btlr
Major Collection:

Gene Information

Sulf2
Name: sulfatase 2
Synonyms: 2010004N24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 72043
Homologene: 10313
Tnf
Name: tumor necrosis factor
Synonyms: TNF-alpha, tumor necrosis factor-alpha, TNF alpha, TNFalpha, DIF, Tnfsf1a, Tnfa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 21926
Homologene: 496
Ehmt1
Name: euchromatic histone methyltransferase 1
Synonyms: 9230102N17Rik, KMT1D
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 77683
Homologene: 11698
Mtfp1
Name: mitochondrial fission process 1
Synonyms: 2610507A21Rik, Mtp18, 1700020C11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 67900
Homologene: 32318
Srgap2
Name: SLIT-ROBO Rho GTPase activating protein 2
Synonyms: FBP2, 9930124L22Rik, Fnbp2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 14270
Homologene: 52683
Cdyl2
Name: chromodomain protein, Y chromosome-like 2
Synonyms: 1700029M19Rik, 4930453I21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 75796
Homologene: 41779
Pdk1
Name: pyruvate dehydrogenase kinase, isoenzyme 1
Synonyms: D530020C15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228026
HGNC: HGNC:8809
Homologene: 134437
Ncaph2
Name: non-SMC condensin II complex, subunit H2
Synonyms: 0610010J20Rik, 2610524G04Rik, D15Ertd785e, Kleisin beta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 52683
Homologene: 12045
Dhcr24
Name: 24-dehydrocholesterol reductase
Synonyms: 5830417J06Rik, seladin-1, 3-beta-hydroxysterol delta-24 reductase, 2310076D10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 74754
HGNC: HGNC:2859
Homologene: 8850
Ncor2
Name: nuclear receptor co-repressor 2
Synonyms: SMRTe, SMRT
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 20602
HGNC: HGNC:7673
Homologene: 31370
Actr8
Name: ARP8 actin-related protein 8
Synonyms: ARP8, 5730542K05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 56249
VEGA: 14
Homologene: 11286
Rasal2
Name: RAS protein activator like 2
Synonyms: A330066M24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226525
HGNC: HGNC:9874
Homologene: 35217
Otof
Name: otoferlin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 83762
HGNC: HGNC:8515
Homologene: 12892
Zbtb2
Name: zinc finger and BTB domain containing 2
Synonyms: LOC381990
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 381990
VEGA: 10
Homologene: 10837
Cdk12
Name: cyclin-dependent kinase 12
Synonyms: 1810022J16Rik, Crk7, D11Ertd752e, Crkrs
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 69131
Homologene: 128632
Knstrn
Name: kinetochore-localized astrin/SPAG5 binding
Synonyms: 1700025D04Rik, D2Ertd750e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 51944
Homologene: 12198
Bcl10
Name: B cell leukemia/lymphoma 10
Synonyms: mE10, cE10, BCL-10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 12042
HGNC: HGNC:989
Homologene: 2912
Mkln1
Name: muskelin 1, intracellular mediator containing kelch motifs
Synonyms: A130067F06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 27418
HGNC: HGNC:7109
Homologene: 8305
Frmd8
Name: FERM domain containing 8
Synonyms: 4931429L16Rik, 2310035N23Rik, 1200004M23Rik, iTAP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 67457
Homologene: 32653
Fam135a
Name: family with sequence similarity 135, member A
Synonyms: 4921533L14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 68187
Homologene: 32665
Tbl3
Name: transducin (beta)-like 3
Synonyms: 9430070M15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 213773
Homologene: 4711
Dennd1a
Name: DENN/MADD domain containing 1A
Synonyms: 6030446I19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227801
Homologene: 17141
Kalrn
Name: kalirin, RhoGEF kinase
Synonyms: LOC224126, 2210407G14Rik, Hapip, E530005C20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 545156
HGNC: HGNC:4814
Homologene: 57160
Akr1c18
Name: aldo-keto reductase family 1, member C18
Synonyms: 20alpha-HSD, 20alpha-hydroxysteroid dehydrogenase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 105349
HGNC: HGNC:386
Homologene: 128661
Dach1
Name: dachshund family transcription factor 1
Synonyms: Dac, E130112M23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 13134
HGNC: HGNC:2663
Homologene: 7288
Kat2a
Name: K(lysine) acetyltransferase 2A
Synonyms: PCAF-B/GCN5, 1110051E14Rik, Gcn5, Gcn5l2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 14534
HGNC: HGNC:4201
Homologene: 41343
Ackr4
Name: atypical chemokine receptor 4
Synonyms: VSHK1, CCR11, CCBP2, PPR1, CCX-CKR, A630091E18Rik, Ccrl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 252837
HGNC: HGNC:1611
Homologene: 49474
Usf3
Name: upstream transcription factor family member 3
Synonyms: LOC207806, LOC385650, 5530400K22Rik, Gm608
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 207806
Homologene: 19504
Pitpnm1
Name: phosphatidylinositol transfer protein, membrane-associated 1
Synonyms: DRES9, RdgB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 18739
HGNC: HGNC:9003
Homologene: 3608
Hgsnat
Name: heparan-alpha-glucosaminide N-acetyltransferase
Synonyms: 9430010M12Rik, Tmem76, D8Ertd354e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 52120
Homologene: 15586
Cdc42bpa
Name: CDC42 binding protein kinase alpha
Synonyms: DMPK-like, A930014J19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226751
HGNC: HGNC:1737
Homologene: 55765
Acad10
Name: acyl-Coenzyme A dehydrogenase family, member 10
Synonyms: 2410021P16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 71985
Homologene: 49825
Stradb
Name: STE20-related kinase adaptor beta
Synonyms: PRO1038, D1Ucla2, Als2cr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227154
Homologene: 10237
Lama4
Name: laminin, alpha 4
Synonyms: laminin [a]4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 16775
HGNC: HGNC:6484
Homologene: 37604
Tecta
Name: tectorin alpha
Synonyms: [a]-tectorin, Tctna
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 21683
Homologene: 3955
Dnah17
Name: dynein, axonemal, heavy chain 17
Synonyms: LOC382552, 2810003K23Rik, Dnahcl1, Dnahc17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 69926
HGNC: HGNC:2946
Homologene: 72102
Col27a1
Name: collagen, type XXVII, alpha 1
Synonyms: 5730512J02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 373864
Homologene: 69400
Tgfbi
Name: transforming growth factor, beta induced
Synonyms: bIG-h3, 68kDa, Beta-ig
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 21810
VEGA: 13
Homologene: 37294
Mcc
Name: mutated in colorectal cancers
Synonyms: D18Ertd451e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 328949
HGNC: HGNC:6935
Homologene: 20539
Gm9936
Name: predicted gene 9936
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 791292
VEGA: 5
Ptpdc1
Name: protein tyrosine phosphatase domain containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218232
VEGA: 13
Homologene: 17576
Gm11639
Name: predicted gene 11639
Synonyms: Efcab15, Gm11639
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 105242472
Csmd3
Name: CUB and Sushi multiple domains 3
Synonyms: 4930500N14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239420
Homologene: 65982
Efna5
Name: ephrin A5
Synonyms: AL-1, RAGS, Ephrin-A5, Epl7, EFL-5, LERK-7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 13640
HGNC: HGNC:3225
Homologene: 1482
Nek9
Name: NIMA (never in mitosis gene a)-related expressed kinase 9
Synonyms: C130021H08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 217718
Homologene: 13222
Cadm2
Name: cell adhesion molecule 2
Synonyms: A830029E02Rik, Necl3, SynCAM2, Igsf4d, 2900078E11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 239857
Homologene: 17705
Cacna1b
Name: calcium channel, voltage-dependent, N type, alpha 1B subunit
Synonyms: Cchn1a, alpha(1B), Cav2.2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 12287
HGNC: HGNC:1389
Homologene: 20184
Itgal
Name: integrin alpha L
Synonyms: LFA-1, Cd11a, Ly-21, Ly-15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 16408
HGNC: HGNC:6148
Homologene: 1666
Adgre4
Name: adhesion G protein-coupled receptor E4
Synonyms: EGF-TM7, D17Ertd479e, FIRE, Gpr127, Emr4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 52614
VEGA: 17
Homologene: 64640
Shank2
Name: SH3 and multiple ankyrin repeat domains 2
Synonyms: ProSAP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 210274
Homologene: 105965
Myo5b
Name: myosin VB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 17919
HGNC: HGNC:7603
Homologene: 49481
Vmn2r105
Name: vomeronasal 2, receptor 105
Synonyms: EG627743
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 627743
Homologene: 129680
Cyp2c50
Name: cytochrome P450, family 2, subfamily c, polypeptide 50
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 107141
Homologene: 137231
Pramel17
Name: PRAME like 17
Synonyms: B020004J07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 545662
Homologene: 128627
Aldh1a7
Name: aldehyde dehydrogenase family 1, subfamily A7
Synonyms: Ahd2-like, Aldh-pb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 26358
HGNC: HGNC:402
Homologene: 137245
Tectb
Name: tectorin beta
Synonyms: [b]-tectorin, Tctnb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 21684
Homologene: 7568
Drc1
Name: dynein regulatory complex subunit 1
Synonyms: LOC381738, Gm1060, b2b1654Clo, Ccdc164
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 381738
Homologene: 35977
Adamdec1
Name: ADAM-like, decysin 1
Synonyms: 2210414L24Rik, Dcsn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 58860
VEGA: 14
Homologene: 8711
Olfr693
Name: olfactory receptor 693
Synonyms: GA_x6K02T2PBJ9-9055944-9054994, MOR283-8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258445
Npas1
Name: neuronal PAS domain protein 1
Synonyms: MOP5, bHLHe11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 18142
HGNC: HGNC:7894
Homologene: 1886
2210408I21Rik
Name: RIKEN cDNA 2210408I21 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 72371
Homologene: 89234
Ube2q2
Name: ubiquitin-conjugating enzyme E2Q family member 2
Synonyms: 3010021M21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 109161
Homologene: 45455
Laptm5
Name: lysosomal-associated protein transmembrane 5
Synonyms: E3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 16792
Homologene: 4922
Nrsn2
Name: neurensin 2
Synonyms: LOC228777, Neurensin-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228777
Homologene: 11802
Usp36
Name: ubiquitin specific peptidase 36
Synonyms: 2700002L06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 72344
Homologene: 11828
Tmem132a
Name: transmembrane protein 132A
Synonyms: 6720481D13Rik, Hspa5bp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 98170
Homologene: 75076
Soga3
Name: SOGA family member 3
Synonyms: 6330407J23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 67412
VEGA: 10
Homologene: 28227
Oas1c
Name: 2'-5' oligoadenylate synthetase 1C
Synonyms: Oasl5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 114643
HGNC: HGNC:8086
Homologene: 110815
Btnl7-ps
Name: butyrophilin-like 7, pseudogene
Synonyms: Btnl7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 195349
Olfr58
Name: olfactory receptor 58
Synonyms: IG6, MOR146-7P, GA_x6K02T2PVTD-13523015-13523944, MOR146-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 18358
Homologene: 134093
Cyp4f37
Name: cytochrome P450, family 4, subfamily f, polypeptide 37
Synonyms: Gm9705
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 677156
VEGA: 17
Homologene: 135840
Frmd3
Name: FERM domain containing 3
Synonyms: EPB41L4O, P410, 4.1O, 9430066I12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242506
Homologene: 16012
Zfp593
Name: zinc finger protein 593
Synonyms: E130106C14Rik, 3110024A21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 68040
Homologene: 41070
Vmn1r159
Name: vomeronasal 1 receptor 159
Synonyms: Gm16507
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 670857
Homologene: 104166
C1qc
Name: complement component 1, q subcomponent, C chain
Synonyms: C1qg
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 12262
HGNC: HGNC:1245
Homologene: 32020
Adam1b
Name: a disintegrin and metallopeptidase domain 1b
Synonyms: Ftna, PH-30 alpha, fertilin alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 280667
Homologene: 136485
Olfr545
Name: olfactory receptor 545
Synonyms: GA_x6K02T2PBJ9-5216160-5215210, MOR42-1, S50
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258837
Homologene: 17410
Lsm10
Name: U7 snRNP-specific Sm-like protein LSM10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 116748
Homologene: 13154
Sgpp2
Name: sphingosine-1-phosphate phosphatase 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 433323
Homologene: 51848
Trib3
Name: tribbles pseudokinase 3
Synonyms: Trb3, Nipk, SKIP3, Ifld2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228775
Homologene: 10902
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 24,021,964 bp
  • C to T, chromosome 1 at 58,988,584 bp
  • T to A, chromosome 1 at 78,360,150 bp
  • A to G, chromosome 1 at 131,292,508 bp
  • G to T, chromosome 1 at 157,161,300 bp
  • G to A, chromosome 1 at 180,150,177 bp
  • A to T, chromosome 2 at 24,606,637 bp
  • A to G, chromosome 2 at 24,815,741 bp
  • A to T, chromosome 2 at 37,844,783 bp
  • A to C, chromosome 2 at 71,873,560 bp
  • A to T, chromosome 2 at 118,823,801 bp
  • A to T, chromosome 2 at 152,343,236 bp
  • A to T, chromosome 2 at 152,369,821 bp
  • T to C, chromosome 2 at 166,085,801 bp
  • T to A, chromosome 3 at 145,933,030 bp
  • T to C, chromosome 4 at 63,306,672 bp
  • T to A, chromosome 4 at 74,153,559 bp
  • T to C, chromosome 4 at 101,837,246 bp
  • T to C, chromosome 4 at 106,585,832 bp
  • T to C, chromosome 4 at 126,097,923 bp
  • T to C, chromosome 4 at 130,932,047 bp
  • C to A, chromosome 4 at 134,245,558 bp
  • T to C, chromosome 4 at 136,890,091 bp
  • A to G, chromosome 5 at 30,355,265 bp
  • A to C, chromosome 5 at 30,420,966 bp
  • A to G, chromosome 5 at 114,857,544 bp
  • T to C, chromosome 5 at 120,805,438 bp
  • A to T, chromosome 5 at 121,501,748 bp
  • T to A, chromosome 5 at 121,630,204 bp
  • T to C, chromosome 5 at 125,028,800 bp
  • T to C, chromosome 6 at 31,474,291 bp
  • T to C, chromosome 7 at 16,474,703 bp
  • T to C, chromosome 7 at 22,842,882 bp
  • T to C, chromosome 7 at 102,493,899 bp
  • A to G, chromosome 7 at 106,677,667 bp
  • T to C, chromosome 7 at 127,314,096 bp
  • A to T, chromosome 7 at 144,068,770 bp
  • C to T, chromosome 8 at 25,945,252 bp
  • A to G, chromosome 8 at 116,589,237 bp
  • T to A, chromosome 9 at 19,784,009 bp
  • G to T, chromosome 9 at 42,332,552 bp
  • T to A, chromosome 9 at 55,191,856 bp
  • C to T, chromosome 9 at 104,086,244 bp
  • T to G, chromosome 10 at 4,368,673 bp
  • A to T, chromosome 10 at 29,146,765 bp
  • A to T, chromosome 10 at 39,075,358 bp
  • T to A, chromosome 10 at 39,106,047 bp
  • T to C, chromosome 11 at 4,094,504 bp
  • T to G, chromosome 11 at 98,203,792 bp
  • A to T, chromosome 11 at 100,710,822 bp
  • T to A, chromosome 11 at 104,733,664 bp
  • T to A, chromosome 11 at 118,053,038 bp
  • T to C, chromosome 11 at 118,262,515 bp
  • A to C, chromosome 12 at 85,332,546 bp
  • T to C, chromosome 13 at 4,142,164 bp
  • C to T, chromosome 13 at 48,586,063 bp
  • T to A, chromosome 13 at 56,638,708 bp
  • T to A, chromosome 13 at 77,245,374 bp
  • T to C, chromosome 14 at 29,987,282 bp
  • T to A, chromosome 14 at 68,579,208 bp
  • A to G, chromosome 14 at 97,901,411 bp
  • CCTTTGCGCTT to CCTT, chromosome 15 at 47,741,236 bp
  • C to A, chromosome 15 at 89,370,475 bp
  • C to T, chromosome 16 at 34,310,495 bp
  • T to C, chromosome 16 at 44,216,381 bp
  • G to A, chromosome 16 at 66,815,383 bp
  • A to T, chromosome 17 at 20,227,323 bp
  • A to T, chromosome 17 at 24,703,316 bp
  • C to T, chromosome 17 at 32,625,119 bp
  • A to T, chromosome 17 at 34,533,518 bp
  • T to C, chromosome 17 at 35,200,500 bp
  • T to A, chromosome 17 at 55,778,878 bp
  • A to T, chromosome 17 at 62,881,028 bp
  • G to A, chromosome 18 at 44,443,012 bp
  • A to T, chromosome 18 at 74,654,076 bp
  • T to A, chromosome 19 at 4,106,631 bp
  • C to A, chromosome 19 at 5,874,712 bp
  • A to T, chromosome 19 at 10,859,742 bp
  • T to A, chromosome 19 at 20,699,956 bp
  • C to G, chromosome 19 at 40,090,320 bp
  • C to G, chromosome 19 at 55,180,999 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R2570 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
040428-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.