Strain Name:
C57BL/6J-MtgxR2697Btlr/Mmmh
Stock Number:
040435-MU
Citation ID:
RRID:MMRRC_040435-MU
Other Names:
R2697 (G1), C57BL/6J-MtgxR2697Btlr
Major Collection:

Strain Information

Crhr2
Name: corticotropin releasing hormone receptor 2
Synonyms: Crfr2, CRF-R2, CRFR2beta, CRFR2alpha, CRF 2 receptor, CRH-R2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 12922
HGNC: HGNC:2358
Homologene: 55612
Cradd
Name: CASP2 and RIPK1 domain containing adaptor with death domain
Synonyms: RAIDD
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 12905
VEGA: 10
HGNC: HGNC:2340
Homologene: 2821
U2af2
Name: U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 22185
Homologene: 110853
Rps6ka2
Name: ribosomal protein S6 kinase, polypeptide 2
Synonyms: Rsk3, 90kDa, Rps6ka-rs1, p90rsk, pp90rsk, D17Wsu134e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 20112
VEGA: 17
Homologene: 100680
Gars
Name: glycyl-tRNA synthetase
Synonyms: Sgrp23, GENA202, Gena201
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 353172
HGNC: HGNC:4162
Homologene: 1547
Kif11
Name: kinesin family member 11
Synonyms: Eg5, Knsl1, Kifl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 16551
VEGA: 19
HGNC: HGNC:6388
Homologene: 3322
Ahctf1
Name: AT hook containing transcription factor 1
Synonyms: 6230412P20Rik, Elys
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226747
Homologene: 9142
Gtf3c1
Name: general transcription factor III C 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233863
HGNC: HGNC:4664
Homologene: 31040
Srbd1
Name: S1 RNA binding domain 1
Synonyms: D530025C17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 78586
VEGA: 17
Homologene: 9994
Myo1b
Name: myosin IB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 17912
HGNC: HGNC:7596
Homologene: 7856
Dhrs7b
Name: dehydrogenase/reductase (SDR family) member 7B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216820
Homologene: 41044
Mbd1
Name: methyl-CpG binding domain protein 1
Synonyms: PCM1, Cxxc3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 17190
VEGA: 18
HGNC: HGNC:6916
Homologene: 8414
Tiam1
Name: T cell lymphoma invasion and metastasis 1
Synonyms: D16Ium10, D16Ium10e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 21844
Homologene: 2443
Ccdc117
Name: coiled-coil domain containing 117
Synonyms: 1700026O03Rik, 1110004K02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 104479
Homologene: 15886
Tmem43
Name: transmembrane protein 43
Synonyms: 1200015A22Rik, LUMA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 74122
Homologene: 11532
Slc41a3
Name: solute carrier family 41, member 3
Synonyms: SLC41A1-L2, 1010001P06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 71699
Homologene: 23052
Adra2c
Name: adrenergic receptor, alpha 2c
Synonyms: alpha2-C4, subtype alpha2-C4, [a]2C, alpha2C, Adra-2c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 11553
HGNC: HGNC:283
Homologene: 20170
Rfng
Name: RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
Synonyms: radical fringe
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 19719
HGNC: HGNC:9974
Homologene: 56433
Acaca
Name: acetyl-Coenzyme A carboxylase alpha
Synonyms: acetyl-CoA carboxylase, Acc1, LOC327983, Acac, A530025K05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 107476
HGNC: HGNC:84
Homologene: 31015
Cep120
Name: centrosomal protein 120
Synonyms: Ccdc100
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 225523
VEGA: 18
Homologene: 27415
Zfp799
Name: zinc finger protein 799
Synonyms: 6030490I01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 240064
Homologene: 107106
Cabp7
Name: calcium binding protein 7
Synonyms: calneuron II
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 192650
Homologene: 16364
Adgrl4
Name: adhesion G protein-coupled receptor L4
Synonyms: EGF-TM7 receptor, Etl, 1110033N21Rik, Eltd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 170757
Homologene: 11170
P3h1
Name: prolyl 3-hydroxylase 1
Synonyms: 2410024C15Rik, Gros1, Lepre1, Leprecan
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 56401
Homologene: 10509
Nudt9
Name: nudix (nucleoside diphosphate linked moiety X)-type motif 9
Synonyms: 1190002C07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 74167
HGNC: HGNC:8056
Homologene: 11435
Rap1gds1
Name: RAP1, GTP-GDP dissociation stimulator 1
Synonyms: GDS1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229877
HGNC: HGNC:9859
Homologene: 41422
Arl13b
Name: ADP-ribosylation factor-like 13B
Synonyms: A930014M17Rik, A530097K21Rik, C530009C10Rik, Arl2l1, hnn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 68146
Homologene: 18820
Rbp3
Name: retinol binding protein 3, interstitial
Synonyms: Irbp, Rbp-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 19661
VEGA: 14
HGNC: HGNC:9921
Homologene: 9261
Fgd2
Name: FYVE, RhoGEF and PH domain containing 2
Synonyms: tcs-2, Tcd-2, tcs2, Tcd2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 26382
HGNC: HGNC:3664
Homologene: 8438
Fam184b
Name: family with sequence similarity 184, member B
Synonyms: 9630031F12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 58227
Homologene: 137353
Cpsf1
Name: cleavage and polyadenylation specific factor 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 94230
VEGA: 15
HGNC: HGNC:2324
Homologene: 40865
Zfyve9
Name: zinc finger, FYVE domain containing 9
Synonyms: Madhip
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230597
HGNC: HGNC:6775
Homologene: 3527
Polq
Name: polymerase (DNA directed), theta
Synonyms: A430110D14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 77782
HGNC: HGNC:9186
Homologene: 32727
Armc3
Name: armadillo repeat containing 3
Synonyms: 4921513G22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 70882
Homologene: 31589
Dnah9
Name: dynein, axonemal, heavy chain 9
Synonyms: D11Ertd686e, Dnahc9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237806
HGNC: HGNC:2953
Homologene: 20357
Hc
Name: hemolytic complement
Synonyms: C5a, C5, He, Hfib2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 15139
HGNC: HGNC:1331
Homologene: 20412
Osbp2
Name: oxysterol binding protein 2
Synonyms: OSBPL1, ORP-4, 1700095P05Rik, C630001G20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 74309
HGNC: HGNC:8504
Homologene: 75303
Or11g27
Name: olfactory receptor family 11 subfamily G member 27
Synonyms: GA_x6K02T2N6FY-3870-3385, GA_x6K02T2N6FY-2320-2039, GA_x6K02T2PMLR-6243196-6244132, MOR106-8P, MOR106-14, Olfr265, Olfr743-ps1, Olfr264, Olfr743
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 219019
Homologene: 74163
Myo1h
Name: myosin 1H
Synonyms: 4631401O15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231646
Homologene: 82639
Odad2
Name: outer dynein arm docking complex subunit 2
Synonyms: 4930463I21Rik, Armc4, b2b227.1Clo, b2b643Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 74934
VEGA: 18
Homologene: 9992
Sult1e1
Name: sulfotransferase family 1E, member 1
Synonyms: Ste, EST
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 20860
Homologene: 101388
Or2h15
Name: olfactory receptor family 2 subfamily H member 15
Synonyms: MOR256-49, GA_x6K02T2PSCP-2579687-2578746, Olfr132
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 257889
Homologene: 46430
Myo5c
Name: myosin VC
Synonyms: 9130003O20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 208943
VEGA: 9
HGNC: HGNC:7604
Homologene: 135711
Macrod1
Name: mono-ADP ribosylhydrolase 1
Synonyms: D930010J01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 107227
VEGA: 19
Homologene: 8549
Adam7
Name: a disintegrin and metallopeptidase domain 7
Synonyms: EAP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 11500
HGNC: HGNC:214
Homologene: 2830
Pon3
Name: paraoxonase 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 269823
HGNC: HGNC:9206
Homologene: 37371
Ano3
Name: anoctamin 3
Synonyms: B230324K02Rik, Tmem16c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228432
Homologene: 57147
Krt1
Name: keratin 1
Synonyms: Krt2-1, Krt-2.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 16678
VEGA: 15
HGNC: HGNC:6412
Homologene: 38146
Tent5a
Name: terminal nucleotidyltransferase 5A
Synonyms: D930050G01Rik, BAP014, Fam46a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 212943
Homologene: 23032
Gpam
Name: glycerol-3-phosphate acyltransferase, mitochondrial
Synonyms: GPAT1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 14732
Homologene: 7343
Zfp58
Name: zinc finger protein 58
Synonyms: Mfg-1, Mfg1, A530094I17Rik, Zfp817
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 238693
Yipf7
Name: Yip1 domain family, member 7
Synonyms: Yip1b, 2310016N21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 75581
Homologene: 69367
A630073D07Rik
Name: RIKEN cDNA A630073D07 gene
Synonyms: LOC381819
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 381819
Tacr1
Name: tachykinin receptor 1
Synonyms: neurokinin receptor 1, NK-1R, NK1-R, NK1 receptor, Tac1r, substance p receptor, SPr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 21336
Homologene: 20288
Gm340
Name: predicted gene 340
Synonyms: LOC381224
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Kcnq5
Name: potassium voltage-gated channel, subfamily Q, member 5
Synonyms: 9230107O05Rik, D1Mgi1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226922
HGNC: HGNC:6299
Homologene: 28270
Ifi213
Name: interferon activated gene 213
Synonyms: E030037K03Rik, Pydc4, Pyr-A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 623121
Homologene: 115929
Tacstd2
Name: tumor-associated calcium signal transducer 2
Synonyms: GA733-1, EGP-1, TROP2, Ly97
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 56753
Homologene: 1763
Or6c65
Name: olfactory receptor family 6 subfamily C member 65
Synonyms: GA_x6K02T2PULF-11446184-11447122, MOR112-2, Olfr808
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 258930
Homologene: 17438
Or2a57
Name: olfactory receptor family 2 subfamily A member 57
Synonyms: IB12, MOR261-9, GA_x6K02T2P3E9-4322325-4321360, Olfr47
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 18346
Homologene: 133700
Mtfmt
Name: mitochondrial methionyl-tRNA formyltransferase
Synonyms: 2310020P08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 69606
Homologene: 12320
Tmem181a
Name: transmembrane protein 181A
Synonyms: 5930418K15Rik, Gpr178, C76977, Tmem181
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 77106
Homologene: 44787
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 21,479,432 bp
  • T to C, chromosome 1 at 51,863,358 bp
  • A to T, chromosome 1 at 173,567,276 bp
  • T to C, chromosome 1 at 179,752,532 bp
  • T to C, chromosome 2 at 19,303,935 bp
  • T to C, chromosome 2 at 35,032,091 bp
  • T to C, chromosome 2 at 110,794,960 bp
  • C to T, chromosome 3 at 138,983,721 bp
  • A to C, chromosome 3 at 151,510,623 bp
  • T to C, chromosome 4 at 108,695,819 bp
  • A to G, chromosome 4 at 119,247,180 bp
  • C to A, chromosome 5 at 35,280,698 bp
  • A to G, chromosome 5 at 45,553,224 bp
  • T to A, chromosome 5 at 69,541,140 bp
  • T to C, chromosome 5 at 87,578,538 bp
  • T to C, chromosome 5 at 104,064,993 bp
  • A to G, chromosome 5 at 114,355,213 bp
  • A to G, chromosome 6 at 5,232,429 bp
  • A to T, chromosome 6 at 43,236,126 bp
  • A to T, chromosome 6 at 55,061,065 bp
  • A to G, chromosome 6 at 55,102,830 bp
  • T to A, chromosome 6 at 67,535,219 bp
  • T to A, chromosome 6 at 82,492,597 bp
  • C to A, chromosome 6 at 90,642,320 bp
  • A to G, chromosome 6 at 91,479,929 bp
  • T to C, chromosome 6 at 132,626,656 bp
  • G to A, chromosome 7 at 5,067,546 bp
  • T to A, chromosome 7 at 125,643,954 bp
  • T to C, chromosome 9 at 65,452,021 bp
  • T to C, chromosome 9 at 75,242,882 bp
  • T to C, chromosome 9 at 85,324,740 bp
  • A to G, chromosome 10 at 95,175,945 bp
  • G to A, chromosome 10 at 129,767,924 bp
  • A to T, chromosome 11 at 3,863,407 bp
  • C to T, chromosome 11 at 4,738,837 bp
  • T to C, chromosome 11 at 5,534,888 bp
  • A to G, chromosome 11 at 60,855,696 bp
  • T to C, chromosome 11 at 65,955,626 bp
  • T to A, chromosome 11 at 84,364,413 bp
  • C to A, chromosome 11 at 120,784,039 bp
  • G to A, chromosome 13 at 67,491,005 bp
  • C to T, chromosome 14 at 33,956,018 bp
  • C to T, chromosome 14 at 50,533,781 bp
  • A to T, chromosome 14 at 68,514,783 bp
  • T to C, chromosome 15 at 76,599,329 bp
  • T to A, chromosome 15 at 101,846,929 bp
  • T to G, chromosome 16 at 37,042,153 bp
  • A to G, chromosome 16 at 62,801,802 bp
  • T to C, chromosome 16 at 89,793,164 bp
  • A to G, chromosome 17 at 6,299,353 bp
  • T to G, chromosome 17 at 7,300,322 bp
  • A to T, chromosome 17 at 29,376,921 bp
  • G to A, chromosome 17 at 32,820,240 bp
  • A to G, chromosome 17 at 38,131,009 bp
  • T to A, chromosome 17 at 86,115,311 bp
  • G to T, chromosome 18 at 7,088,570 bp
  • C to T, chromosome 18 at 53,740,125 bp
  • T to C, chromosome 18 at 74,273,617 bp
  • T to C, chromosome 19 at 7,196,792 bp
  • T to A, chromosome 19 at 37,411,615 bp
  • T to A, chromosome 19 at 41,584,027 bp
  • C to T, chromosome 19 at 55,083,209 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R2697 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
040435-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.