Strain Name:
C57BL/6J-MtgxR2872Btlr/Mmmh
Stock Number:
040460-MU
Citation ID:
RRID:MMRRC_040460-MU
Other Names:
R2872 (G1), C57BL/6J-MtgxR2872Btlr
Major Collection:

Gene Information

Matr3
Name: matrin 3
Synonyms: D030046F20Rik, 2810017I02Rik, 1110061A14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 17184
HGNC: HGNC:6912
Homologene: 7830
Gria2
Name: glutamate receptor, ionotropic, AMPA2 (alpha 2)
Synonyms: GluR-B, GluR2, Glur-2, Glur2, GluA2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 14800
HGNC: HGNC:4572
Homologene: 20225
Plin2
Name: perilipin 2
Synonyms: Adrp, adipophilin, ADPH, Adfp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 11520
HGNC: HGNC:248
Homologene: 872
Arhgef10
Name: Rho guanine nucleotide exchange factor (GEF) 10
Synonyms: 6430549H08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234094
Homologene: 22827
Cilk1
Name: ciliogenesis associated kinase 1
Synonyms: 2210420N10Rik, Ick
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 56542
Homologene: 69218
Prps1
Name: phosphoribosyl pyrophosphate synthetase 1
Synonyms: Prps-1, 2310010D17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 19139
HGNC: HGNC:9462
Homologene: 68275
Mtor
Name: mechanistic target of rapamycin kinase
Synonyms: FKBP-rapamycin-associated protein FRAP, 2610315D21Rik, RAPT1, RAFT1, flat, Frap1, mechanistic target of rapamycin (serine/threonine kinase)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 56717
HGNC: HGNC:3942
Homologene: 3637
Rapgef6
Name: Rap guanine nucleotide exchange factor (GEF) 6
Synonyms: RA-GEF-2, PDZ-GEF2, Pdzgef2, C030018K18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 192786
Homologene: 22968
Parp1
Name: poly (ADP-ribose) polymerase family, member 1
Synonyms: PARP, sPARP-1, Adprp, parp-1, 5830444G22Rik, Adprt1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 11545
HGNC: HGNC:270
Homologene: 1222
Tfdp1
Name: transcription factor Dp 1
Synonyms: Dp1, Drtf1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 21781
Homologene: 38276
Tbc1d8
Name: TBC1 domain family, member 8
Synonyms: BUB2-like protein 1, HBLP1, AD3, GRAM domain
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 54610
Homologene: 31421
Myo9b
Name: myosin IXb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 17925
HGNC: HGNC:7609
Homologene: 3058
Zfp292
Name: zinc finger protein 292
Synonyms: Zn-16, Zn-15, Krox-10, Zfp-15, 9430062L07Rik, 5730450D02Rik, Zfp15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 30046
Homologene: 8493
Als2
Name: alsin Rho guanine nucleotide exchange factor
Synonyms: 3222402C23Rik, Als2cr6, 9430073A21Rik, Alsin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 74018
HGNC: HGNC:443
Homologene: 23264
Eef2
Name: eukaryotic translation elongation factor 2
Synonyms: Ef-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 13629
VEGA: 10
HGNC: HGNC:3214
Homologene: 134867
Ctnnd1
Name: catenin (cadherin associated protein), delta 1
Synonyms: P120, Ctnnd, p120-catenin, Catns
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 12388
HGNC: HGNC:2515
Homologene: 1017
Plekhg5
Name: pleckstrin homology domain containing, family G (with RhoGef domain) member 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 269608
Homologene: 10768
Klf8
Name: Kruppel-like factor 8
Synonyms: ZNF74, BKLF3, A830097P10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 245671
HGNC: HGNC:6351
Homologene: 68549
Ostc
Name: oligosaccharyltransferase complex subunit (non-catalytic)
Synonyms: 5730557H03Rik, 2310008M10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 66357
Homologene: 10933
Ppp1r7
Name: protein phosphatase 1, regulatory subunit 7
Synonyms: SDS22, 2310014J01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 66385
HGNC: HGNC:9295
Homologene: 2032
Plxna3
Name: plexin A3
Synonyms: Plxn4, SEX, Plxn3, Plxa3, PlexA3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 18846
HGNC: HGNC:9101
Homologene: 7481
Slc39a8
Name: solute carrier family 39 (metal ion transporter), member 8
Synonyms: BIGM103, 4933419D20Rik, ZIP8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 67547
Homologene: 11155
Hjurp
Name: Holliday junction recognition protein
Synonyms: C330011F01Rik, A730008H23Rik, 6430706D22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 381280
Homologene: 10184
Plekhg1
Name: pleckstrin homology domain containing, family G (with RhoGef domain) member 1
Synonyms: D10Ertd733e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 213783
Homologene: 18897
Nsun2
Name: NOL1/NOP2/Sun domain family member 2
Synonyms: Misu
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 28114
Homologene: 9817
Atp6v1g1
Name: ATPase, H+ transporting, lysosomal V1 subunit G1
Synonyms: 1810024D14Rik, VAG1, ATP6J, Vma10, Atp6g1, lysosomal 13kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 66290
HGNC: HGNC:864
Homologene: 31272
Knop1
Name: lysine rich nucleolar protein 1
Synonyms: Tsg118, 2310008H09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 66356
Homologene: 49729
2700049A03Rik
Name: RIKEN cDNA 2700049A03 gene
Synonyms: talpid3, Ta3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 76967
Homologene: 8839
Ndufs1
Name: NADH:ubiquinone oxidoreductase core subunit S1
Synonyms: 9930026A05Rik, 5830412M15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227197
HGNC: HGNC:7707
Homologene: 3670
Mideas
Name: mitotic deacetylase associated SANT domain protein
Synonyms: 9430029N19Rik, C130039O16Rik, Elmsan1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 238317
Homologene: 19330
Ift172
Name: intraflagellar transport 172
Synonyms: wim, 4930553F24Rik, avc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 67661
Homologene: 15202
Trpa1
Name: transient receptor potential cation channel, subfamily A, member 1
Synonyms: ANKTM1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 277328
HGNC: HGNC:497
Homologene: 7189
Atp12a
Name: ATPase, H+/K+ transporting, nongastric, alpha polypeptide
Synonyms: HKalpha2, cHKA, Atp1al1, ATPase H+K+-transporting, alpha 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 192113
VEGA: 14
Homologene: 68197
Rel
Name: reticuloendotheliosis oncogene
Synonyms: c-Rel
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 19696
HGNC: HGNC:9954
Homologene: 2182
Reln
Name: reelin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 19699
HGNC: HGNC:9957
Homologene: 3699
Ttn
Name: titin
Synonyms: connectin, L56, mdm, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, shru
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22138
Homologene: 130650
Hmcn1
Name: hemicentin 1
Synonyms: LOC240793, EG545370
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 545370
Homologene: 23741
Col12a1
Name: collagen, type XII, alpha 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12816
HGNC: HGNC:2188
Homologene: 3217
Eif3f
Name: eukaryotic translation initiation factor 3, subunit F
Synonyms: 0610037M02Rik, Eif3s5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 66085
HGNC: HGNC:3275
Homologene: 2783
Gpr35
Name: G protein-coupled receptor 35
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 64095
HGNC: HGNC:4492
Homologene: 3874
Hdhd2
Name: haloacid dehalogenase-like hydrolase domain containing 2
Synonyms: 0610039H12Rik, 3110052N05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 76987
Homologene: 12667
Mroh2a
Name: maestro heat-like repeat family member 2A
Synonyms: ENSMUSG00000044873, OTTMUSG00000020804, Heatr7b1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 100040766
Homologene: 85300
Nox3
Name: NADPH oxidase 3
Synonyms: het, nmf250
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224480
HGNC: HGNC:7890
Homologene: 49435
Slc6a9
Name: solute carrier family 6 (neurotransmitter transporter, glycine), member 9
Synonyms: Glyt-1, Glyt1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 14664
Homologene: 5050
Abca8b
Name: ATP-binding cassette, sub-family A (ABC1), member 8b
Synonyms: Abca8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 27404
HGNC: HGNC:38
Homologene: 56029
Tgm7
Name: transglutaminase 7
Synonyms: TGz
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 640543
Homologene: 14192
Nlrc3
Name: NLR family, CARD domain containing 3
Synonyms: D230007K08Rik, Caterpiller 16.2, CLR16.2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 268857
Homologene: 18720
Plcl1
Name: phospholipase C-like 1
Synonyms: PLC-L, C230017K02Rik, PRIP-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227120
HGNC: HGNC:9063
Homologene: 38155
Shoc1
Name: shortage in chiasmata 1
Synonyms: LOC242489, Gm426, AI481877, Mzip2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100155
Homologene: 79783
Sel1l3
Name: sel-1 suppressor of lin-12-like 3 (C. elegans)
Synonyms: 2310045A20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231238
Homologene: 9054
Palmd
Name: palmdelphin
Synonyms: 4631423C22Rik, PALML
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 114301
Homologene: 9804
Polg2
Name: polymerase (DNA directed), gamma 2, accessory subunit
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 50776
HGNC: HGNC:9180
Homologene: 5221
Gmip
Name: Gem-interacting protein
Synonyms: 5031419I10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 78816
Homologene: 9570
Pkd1l2
Name: polycystic kidney disease 1 like 2
Synonyms: 1700126L06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 76645
Homologene: 124481
Igsf9b
Name: immunoglobulin superfamily, member 9B
Synonyms: LOC235086, AI414108
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235086
Homologene: 19472
Armc2
Name: armadillo repeat containing 2
Synonyms: 2610018I05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 213402
Homologene: 41848
Ugt1a1
Name: UDP glucuronosyltransferase 1 family, polypeptide A1
Synonyms: Gnt1, Udpgt-1a, UGT1A01, UgtBr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 394436
Homologene: 128034
Tnni3k
Name: TNNI3 interacting kinase
Synonyms: Cark, D830019J24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 435766
Homologene: 41084
Uevld
Name: UEV and lactate/malate dehyrogenase domains
Synonyms: 8430408E05Rik, Attp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 54122
Homologene: 69251
Hdac10
Name: histone deacetylase 10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 170787
Homologene: 23749
Notum
Name: notum palmitoleoyl-protein carboxylesterase
Synonyms: 5730593N15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 77583
Homologene: 45335
Tdpoz3
Name: TD and POZ domain containing 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 399674
Homologene: 128308
Olfr1510
Name: olfactory receptor 1510
Synonyms: GA_x6K02T2RJGY-583652-584608, MOR223-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 258423
HGNC: HGNC:8170
Homologene: 87788
Spsb4
Name: splA/ryanodine receptor domain and SOCS box containing 4
Synonyms: D030068E18Rik, Ssb4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 211949
Homologene: 25315
Adamts17
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 17
Synonyms: AU023434
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233332
Homologene: 16373
AC140364.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Ak8
Name: adenylate kinase 8
Synonyms: 1190002A17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 68870
Homologene: 17622
Otud4
Name: OTU domain containing 4
Synonyms: 4930431L18Rik, D8Ertd69e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 73945
Homologene: 35370
Smpdl3a
Name: sphingomyelin phosphodiesterase, acid-like 3A
Synonyms: 0610010C24Rik, ASM3A, ASML3A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 57319
Homologene: 4886
Olfr654
Name: olfactory receptor 654
Synonyms: GA_x6K02T2PBJ9-7215221-7216195, MOR38-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258377
Homologene: 90859
Paqr5
Name: progestin and adipoQ receptor family member V
Synonyms: 0610010I15Rik, mPRg
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 74090
Homologene: 9788
Olfr99
Name: olfactory receptor 99
Synonyms: MOR156-1, GA_x6K02T2PSCP-1720261-1719344
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 258508
Homologene: 74030
Kif1c
Name: kinesin family member 1C
Synonyms: N-3 kinsin, D11Bwg1349e, B430105J22Rik, Orch3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 16562
HGNC: HGNC:6317
Homologene: 4821
Frmpd4
Name: FERM and PDZ domain containing 4
Synonyms: LOC237234, Pdzk10, Pdzd10, PKAP1, Preso1, Preso
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 333605
Homologene: 45843
Gpr156
Name: G protein-coupled receptor 156
Synonyms: Gababl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 239845
VEGA: 16
Homologene: 17683
Rasl12
Name: RAS-like, family 12
Synonyms: 4631404I11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 70784
VEGA: 9
Homologene: 9565
Cyp4a14
Name: cytochrome P450, family 4, subfamily a, polypeptide 14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 13119
Homologene: 134697
Olfr419
Name: olfactory receptor 419
Synonyms: GA_x6K02T2P20D-20891507-20892448, MOR267-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 258710
Homologene: 72017
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 14,887,620 bp
  • A to G, chromosome 1 at 39,405,317 bp
  • A to T, chromosome 1 at 55,697,150 bp
  • A to G, chromosome 1 at 59,211,137 bp
  • A to G, chromosome 1 at 63,164,723 bp
  • AT to A, chromosome 1 at 88,212,371 bp
  • GCCC to GC, chromosome 1 at 88,232,257 bp
  • GT to GTT, chromosome 1 at 88,266,524 bp
  • G to A, chromosome 1 at 92,983,126 bp
  • T to A, chromosome 1 at 93,357,863 bp
  • A to T, chromosome 1 at 150,738,716 bp
  • T to C, chromosome 1 at 174,250,526 bp
  • A to G, chromosome 1 at 180,573,665 bp
  • T to C, chromosome 2 at 28,742,720 bp
  • A to G, chromosome 2 at 76,750,851 bp
  • C to T, chromosome 2 at 84,620,888 bp
  • G to A, chromosome 2 at 121,109,693 bp
  • G to A, chromosome 3 at 80,702,492 bp
  • T to A, chromosome 3 at 93,826,428 bp
  • T to C, chromosome 3 at 116,923,751 bp
  • T to C, chromosome 3 at 130,703,508 bp
  • T to A, chromosome 3 at 135,886,793 bp
  • C to T, chromosome 3 at 154,938,750 bp
  • G to A, chromosome 4 at 34,808,595 bp
  • A to C, chromosome 4 at 59,093,850 bp
  • A to G, chromosome 4 at 63,550,021 bp
  • A to G, chromosome 4 at 86,668,678 bp
  • C to A, chromosome 4 at 115,487,301 bp
  • T to A, chromosome 4 at 117,849,381 bp
  • T to A, chromosome 4 at 148,540,030 bp
  • T to A, chromosome 4 at 152,107,503 bp
  • T to A, chromosome 5 at 8,180,863 bp
  • C to T, chromosome 5 at 22,049,791 bp
  • C to T, chromosome 5 at 31,257,861 bp
  • C to T, chromosome 5 at 53,137,883 bp
  • T to C, chromosome 7 at 46,947,945 bp
  • T to C, chromosome 7 at 67,027,794 bp
  • T to C, chromosome 7 at 104,588,493 bp
  • G to A, chromosome 7 at 108,940,881 bp
  • T to C, chromosome 7 at 118,855,963 bp
  • C to A, chromosome 8 at 13,372,922 bp
  • T to C, chromosome 8 at 14,975,093 bp
  • A to G, chromosome 8 at 14,975,666 bp
  • T to A, chromosome 8 at 69,816,367 bp
  • T to C, chromosome 8 at 71,290,966 bp
  • T to A, chromosome 8 at 79,661,073 bp
  • C to T, chromosome 8 at 117,038,164 bp
  • A to G, chromosome 9 at 27,322,223 bp
  • A to T, chromosome 9 at 61,968,779 bp
  • A to G, chromosome 9 at 65,408,323 bp
  • A to T, chromosome 9 at 78,140,100 bp
  • A to T, chromosome 9 at 79,699,549 bp
  • G to T, chromosome 9 at 96,996,018 bp
  • T to G, chromosome 10 at 3,963,982 bp
  • C to T, chromosome 10 at 41,966,700 bp
  • T to A, chromosome 10 at 57,802,530 bp
  • GCCC to GCCCC, chromosome 10 at 81,178,767 bp
  • T to C, chromosome 11 at 23,761,129 bp
  • T to A, chromosome 11 at 54,661,175 bp
  • A to G, chromosome 11 at 70,724,081 bp
  • A to G, chromosome 11 at 106,775,425 bp
  • A to G, chromosome 11 at 109,955,176 bp
  • A to G, chromosome 11 at 120,660,196 bp
  • T to C, chromosome 12 at 71,154,756 bp
  • C to T, chromosome 12 at 84,156,471 bp
  • A to G, chromosome 13 at 69,629,682 bp
  • T to G, chromosome 14 at 52,410,861 bp
  • A to G, chromosome 14 at 56,386,950 bp
  • G to T, chromosome 15 at 89,125,856 bp
  • T to C, chromosome 16 at 3,957,326 bp
  • T to A, chromosome 16 at 37,992,223 bp
  • T to C, chromosome 17 at 3,682,916 bp
  • A to G, chromosome 17 at 37,279,976 bp
  • T to A, chromosome 18 at 35,572,296 bp
  • T to C, chromosome 18 at 76,955,006 bp
  • T to A, chromosome X at 74,339,396 bp
  • C to T, chromosome X at 140,471,994 bp
  • A to T, chromosome X at 153,382,682 bp
  • A to T, chromosome X at 167,477,247 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R2872 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
040460-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.