Strain Name:
C57BL/6J-MtgxR3055Btlr/Mmmh
Stock Number:
040564-MU
Citation ID:
RRID:MMRRC_040564-MU
Other Names:
R3055 (G1), C57BL/6J-MtgxR3055Btlr
Major Collection:

Gene Information

Drd4
Name: dopamine receptor D4
Synonyms: Drd-4, D4R
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 13491
HGNC: HGNC:3025
Homologene: 20215
Rictor
Name: RPTOR independent companion of MTOR, complex 2
Synonyms: 6030405M08Rik, D530039E11Rik, 4921505C17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 78757
VEGA: 15
Homologene: 34317
Stk11ip
Name: serine/threonine kinase 11 interacting protein
Synonyms: LKB1IP, LIP1, 1200014D22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 71728
Homologene: 12406
Mier3
Name: MIER family member 3
Synonyms: D130064H19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 218613
Homologene: 18196
Mrpl20
Name: mitochondrial ribosomal protein L20
Synonyms: 4930425I20Rik, 2610008D01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 66448
Homologene: 9941
Fxr1
Name: fragile X mental retardation gene 1, autosomal homolog
Synonyms: 1110050J02Rik, 9530073J07Rik, Fxr1h, Fxr1p
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 14359
HGNC: HGNC:4023
Homologene: 3573
Mms19
Name: MMS19 cytosolic iron-sulfur assembly component
Synonyms: Mms19l, 2610042O15Rik, C86341, Mms19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 72199
Homologene: 41480
Bard1
Name: BRCA1 associated RING domain 1
Synonyms: ENSMUSG00000073653, ENSMUSG00000060893
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 12021
HGNC: HGNC:952
Homologene: 400
Atxn10
Name: ataxin 10
Synonyms: TEG-169, E46, Tex169, Sca10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 54138
VEGA: 15
Homologene: 40858
Ints12
Name: integrator complex subunit 12
Synonyms: 1110020M19Rik, A230056J18Rik, 4930529N21Rik, Phf22, 2810027J24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 71793
Homologene: 32474
Rasa2
Name: RAS p21 protein activator 2
Synonyms: 5430433H21Rik, GAP1m
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 114713
HGNC: HGNC:9872
Homologene: 4745
Vps13b
Name: vacuolar protein sorting 13B
Synonyms: 2310042E16Rik, Coh1, 1810042B05Rik, C330002D13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 666173
VEGA: 15
HGNC: HGNC:2183
Homologene: 49516
Prune2
Name: prune homolog 2
Synonyms: 6330414G02Rik, A230083H22Rik, A330102H22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 353211
VEGA: 19
Homologene: 18939
Xrcc4
Name: X-ray repair complementing defective repair in Chinese hamster cells 4
Synonyms: 2310057B22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 108138
Homologene: 2555
Rbm19
Name: RNA binding motif protein 19
Synonyms: 1200009A02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 74111
Homologene: 7158
Kalrn
Name: kalirin, RhoGEF kinase
Synonyms: 2210407G14Rik, Hapip, E530005C20Rik, LOC224126
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 545156
HGNC: HGNC:4814
Homologene: 57160
Abca16
Name: ATP-binding cassette, sub-family A (ABC1), member 16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233810
Homologene: 132942
Slc4a4
Name: solute carrier family 4 (anion exchanger), member 4
Synonyms: NBC, NBC1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 54403
Homologene: 55776
Naip5
Name: NLR family, apoptosis inhibitory protein 5
Synonyms: Birc1e, Naip-rs3, Lgn1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 17951
HGNC: HGNC:7634
Homologene: 113589
Ahrr
Name: aryl-hydrocarbon receptor repressor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 11624
HGNC: HGNC:346
Homologene: 49215
Olfr875
Name: olfactory receptor 875
Synonyms: MOR161-4, GA_x6K02T2PVTD-31458511-31459443
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 258744
Homologene: 121527
Dscam
Name: DS cell adhesion molecule
Synonyms: 4932410A21Rik, Down syndrome cell adhesion molecule
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 13508
HGNC: HGNC:3039
Homologene: 74393
Muc5b
Name: mucin 5, subtype B, tracheobronchial
Synonyms: MUC5, MUC9, 2300002I04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 74180
HGNC: HGNC:7516
Homologene: 136756
Stil
Name: Scl/Tal1 interrupting locus
Synonyms: Sil
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 20460
Homologene: 2283
Ccdc150
Name: coiled-coil domain containing 150
Synonyms: 4930511H11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 78016
Homologene: 15814
Unc5d
Name: unc-5 netrin receptor D
Synonyms: D930029E11Rik, Unc5h4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 210801
Homologene: 15450
Rufy4
Name: RUN and FYVE domain containing 4
Synonyms: F930048N03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 435626
Homologene: 52359
Acad11
Name: acyl-Coenzyme A dehydrogenase family, member 11
Synonyms: 5730439E10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 102632
Homologene: 49896
Tctn2
Name: tectonic family member 2
Synonyms: Tect2, 4432405B04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 67978
Homologene: 11729
Pkd1l2
Name: polycystic kidney disease 1 like 2
Synonyms: 1700126L06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 76645
Homologene: 124481
Serpina3m
Name: serine (or cysteine) peptidase inhibitor, clade A, member 3M
Synonyms: Spi2.4, contrapsin-like, MMSPi2.4, Spi2-rs1, antitrypsin, alpha-1 antiproteinase, Spi-2l, 3e46, MMCM7, Spi-2rs1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 20717
HGNC: HGNC:16
Homologene: 111129
Catsper3
Name: cation channel, sperm associated 3
Synonyms: 4921522D01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 76856
Homologene: 12658
Aldh1l2
Name: aldehyde dehydrogenase 1 family, member L2
Synonyms: D330038I09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 216188
Homologene: 51942
5730596B20Rik
Name: RIKEN cDNA 5730596B20 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 77580
VEGA: 6
Evi5l
Name: ecotropic viral integration site 5 like
Synonyms: 2310039H16Rik, 3110007G05Rik, B130050I23Rik, 1700084G18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 213027
Homologene: 134635
Vmn2r28
Name: vomeronasal 2, receptor 28
Synonyms: EG665255
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 665255
Homologene: 129605
Vmn1r121
Name: vomeronasal 1 receptor 121
Synonyms: Gm8533
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 667240
Homologene: 104166
Ugt2b35
Name: UDP glucuronosyltransferase 2 family, polypeptide B35
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 243085
Homologene: 128251
Radil
Name: Ras association and DIL domains
Synonyms: D930005D10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231858
Homologene: 77648
Gm436
Name: predicted gene 436
Synonyms: LOC230890
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230890
Homologene: 135765
Lgr5
Name: leucine rich repeat containing G protein coupled receptor 5
Synonyms: Gpr49
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 14160
HGNC: HGNC:4504
Homologene: 20807
Cxcr6
Name: chemokine (C-X-C motif) receptor 6
Synonyms: BONZO, STRL33
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 80901
VEGA: 9
Homologene: 38197
Olfr463
Name: olfactory receptor 463
Synonyms: MOR240-1, GA_x6K02T2PAEV-9540823-9539888
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 258408
HGNC: HGNC:8294
Homologene: 64870
Abca7
Name: ATP-binding cassette, sub-family A (ABC1), member 7
Synonyms: Abc51
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 27403
HGNC: HGNC:37
Homologene: 22783
Olfr1094
Name: olfactory receptor 1094
Synonyms: GA_x6K02T2Q125-48321457-48322449, MOR179-7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258362
Homologene: 133609
Tjp3
Name: tight junction protein 3
Synonyms: ZO-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 27375
VEGA: 10
Homologene: 8458
Rasgrf2
Name: RAS protein-specific guanine nucleotide-releasing factor 2
Synonyms: Grf2, 6330417G04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 19418
HGNC: HGNC:9876
Homologene: 2169
Ddx25
Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 25
Synonyms: GRTH
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 30959
Homologene: 8310
Utp14b
Name: UTP14B small subunit processome component
Synonyms: jsd, 4932411L21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 195434
Homologene: 78703
Shfl
Name: shiftless antiviral inhibitor of ribosomal frameshifting
Synonyms: A230050P20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 319278
Homologene: 10165
Yae1d1
Name: Yae1 domain containing 1
Synonyms: 1600012F09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 67008
VEGA: 13
Homologene: 10615
2610042L04Rik
Name: RIKEN cDNA 2610042L04 gene
Synonyms: Tksn, takusan
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 554327
Gldn
Name: gliomedin
Synonyms: Crlg2, CRG-L2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235379
Homologene: 14529
Radx
Name: RPA1 related single stranded DNA binding protein, X-linked
Synonyms: D330045A20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
Alteration at locus: Chemically Induced
NCBI: 102871
Homologene: 9962
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 54,288,842 bp
  • A to G, chromosome 1 at 71,088,231 bp
  • T to C, chromosome 1 at 74,147,663 bp
  • C to A, chromosome 1 at 75,525,843 bp
  • T to A, chromosome 1 at 78,664,725 bp
  • T to C, chromosome 2 at 86,829,127 bp
  • A to G, chromosome 3 at 34,049,184 bp
  • G to A, chromosome 3 at 133,109,365 bp
  • T to A, chromosome 4 at 115,014,069 bp
  • A to G, chromosome 4 at 144,674,698 bp
  • G to T, chromosome 4 at 155,803,872 bp
  • A to T, chromosome 5 at 87,001,598 bp
  • T to A, chromosome 5 at 89,132,507 bp
  • T to C, chromosome 5 at 89,225,948 bp
  • C to T, chromosome 5 at 120,133,010 bp
  • T to A, chromosome 5 at 124,627,144 bp
  • T to C, chromosome 5 at 142,495,406 bp
  • A to T, chromosome 6 at 52,179,128 bp
  • A to T, chromosome 7 at 5,481,392 bp
  • G to A, chromosome 7 at 21,098,465 bp
  • A to G, chromosome 7 at 120,435,851 bp
  • T to C, chromosome 7 at 141,294,479 bp
  • G to T, chromosome 7 at 141,864,041 bp
  • C to T, chromosome 8 at 4,191,603 bp
  • A to T, chromosome 8 at 28,761,891 bp
  • T to A, chromosome 8 at 117,068,315 bp
  • AGAGGAGGAGGAGGAGGAGGAGGAGGA to AGAGGAGGAGGAGGAGGAGGAGGA, chromosome 9 at 20,873,717 bp
  • A to G, chromosome 9 at 35,551,351 bp
  • G to T, chromosome 9 at 37,773,193 bp
  • A to T, chromosome 9 at 54,338,523 bp
  • G to A, chromosome 9 at 96,611,473 bp
  • A to G, chromosome 9 at 104,076,336 bp
  • A to T, chromosome 9 at 123,810,464 bp
  • G to A, chromosome 10 at 79,999,747 bp
  • T to C, chromosome 10 at 81,280,507 bp
  • T to C, chromosome 10 at 83,502,472 bp
  • T to A, chromosome 10 at 115,466,123 bp
  • A to G, chromosome 11 at 87,893,372 bp
  • T to C, chromosome 12 at 104,391,446 bp
  • T to C, chromosome 13 at 17,993,242 bp
  • T to C, chromosome 13 at 55,808,896 bp
  • A to G, chromosome 13 at 74,224,887 bp
  • T to C, chromosome 13 at 90,062,077 bp
  • A to G, chromosome 13 at 92,029,075 bp
  • T to C, chromosome 13 at 100,221,878 bp
  • T to A, chromosome 13 at 111,691,303 bp
  • A to G, chromosome 14 at 4,348,878 bp
  • G to A, chromosome 15 at 6,778,231 bp
  • A to G, chromosome 15 at 35,646,361 bp
  • A to G, chromosome 15 at 85,387,005 bp
  • C to A, chromosome 16 at 34,198,382 bp
  • G to A, chromosome 16 at 96,801,355 bp
  • A to G, chromosome 19 at 17,125,043 bp
  • A to T, chromosome 19 at 41,950,088 bp
  • T to A, chromosome X at 139,511,557 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3055 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040564-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.