Strain Name:
C57BL/6J-MtgxR3078Btlr/Mmmh
Stock Number:
040568-MU
Citation ID:
RRID:MMRRC_040568-MU
Other Names:
R3078 (G1), C57BL/6J-MtgxR3078Btlr
Major Collection:

Gene Information

Alg10b
Name: asparagine-linked glycosylation 10B (alpha-1,2-glucosyltransferase)
Synonyms: Deaf1, LOC380959, nse5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 380959
VEGA: 15
Homologene: 6030
Meis1
Name: Meis homeobox 1
Synonyms: C530044H18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 17268
HGNC: HGNC:7000
Homologene: 86803
Abca12
Name: ATP-binding cassette, sub-family A (ABC1), member 12
Synonyms: 4832428G11Rik, 4833417A11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 74591
Homologene: 45441
Dock6
Name: dedicator of cytokinesis 6
Synonyms: 2410095B20Rik, 4931431C02Rik, C330023D02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 319899
VEGA: 9
Homologene: 83291
Stau1
Name: staufen double-stranded RNA binding protein 1
Synonyms: 5830401L18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20853
Homologene: 3384
Dynlrb1
Name: dynein light chain roadblock-type 1
Synonyms: DNLC2A, 2010320M17Rik, 2010012N15Rik, Dncl2a, km23-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 67068
Homologene: 69161
Cct8
Name: chaperonin containing Tcp1, subunit 8 (theta)
Synonyms: Cctq, Tcpq
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 12469
HGNC: HGNC:1623
Homologene: 4802
Herc2
Name: HECT and RLD domain containing E3 ubiquitin protein ligase 2
Synonyms: D7H15F32S1, D15F32S1h, D7H15F37S1, rjs, jdf2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 15204
HGNC: HGNC:4868
Homologene: 3430
Ifnar2
Name: interferon (alpha and beta) receptor 2
Synonyms: Ifnar-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 15976
HGNC: HGNC:5433
Homologene: 49242
Inpp5j
Name: inositol polyphosphate 5-phosphatase J
Synonyms: Pipp, Pib5pa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 170835
HGNC: HGNC:8956
Homologene: 8682
Clca4a
Name: chloride channel accessory 4A
Synonyms: 9130020L07Rik, Clca6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 99663
HGNC: HGNC:2018
Homologene: 40808
Plaa
Name: phospholipase A2, activating protein
Synonyms: D4Ertd618e, Ufd3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 18786
HGNC: HGNC:9043
Homologene: 3138
Mnt
Name: max binding protein
Synonyms: Rox, bHLHd3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 17428
HGNC: HGNC:7188
Homologene: 7842
Wnt5a
Name: wingless-type MMTV integration site family, member 5A
Synonyms: Wnt-5a, 8030457G12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 22418
Homologene: 20720
Mfsd14a
Name: major facilitator superfamily domain containing 14A
Synonyms: Hiat1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 15247
Homologene: 22456
Adgrd1
Name: adhesion G protein-coupled receptor D1
Synonyms: E230012M21Rik, Gpr133
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 243277
Homologene: 34616
Med28
Name: mediator complex subunit 28
Synonyms: Eg1, 1500003D12Rik, magicin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 66999
Homologene: 11873
Cmya5
Name: cardiomyopathy associated 5
Synonyms: Myospryn, 2310076E16Rik, 2310076E21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 76469
VEGA: 13
Homologene: 137367
Wdr93
Name: WD repeat domain 93
Synonyms: EG626359
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 626359
Homologene: 56878
Ugcg
Name: UDP-glucose ceramide glucosyltransferase
Synonyms: GlcT-1, Epcs21, Ugcgl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 22234
Homologene: 37763
C5ar2
Name: complement component 5a receptor 2
Synonyms: C5L2, E030029A11Rik, Gpr77
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 319430
HGNC: HGNC:4527
Homologene: 49549
Gm10801
Name: predicted gene 10801
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Vmn2r2
Name: vomeronasal 2, receptor 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 100125586
Homologene: 129753
Myo7b
Name: myosin VIIB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 17922
HGNC: HGNC:7607
Homologene: 81947
Ltbp2
Name: latent transforming growth factor beta binding protein 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 16997
HGNC: HGNC:6715
Homologene: 369
Npr2
Name: natriuretic peptide receptor 2
Synonyms: guanylyl cyclase-B, cn, pwe
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230103
HGNC: HGNC:7944
Homologene: 2970
Olfr389
Name: olfactory receptor 389
Synonyms: GA_x6K02T2P1NL-3932085-3931147, MOR135-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 259011
Homologene: 85925
Myoz1
Name: myozenin 1
Synonyms: FATZ, calsarcin-2, 2310001N11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 59011
VEGA: 14
Homologene: 23311
Fbxw10
Name: F-box and WD-40 domain protein 10
Synonyms: SM2SH2, SM25H2, Fbw10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 213980
Homologene: 32757
Slc28a2b
Name: solute carrier family 28 member 2b
Synonyms: Gm14085
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 381417
Mto1
Name: mitochondrial tRNA translation optimization 1
Synonyms: 2310039H01Rik, 5730419A02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 68291
Homologene: 5876
Nrxn3
Name: neurexin III
Synonyms: neurexin III beta, neurexin III alpha, neurexin III beta, neurexin III alpha, 9330112C09Rik, D12Bwg0831e, 4933401A11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 18191
HGNC: HGNC:8010
Homologene: 83225
Kif14
Name: kinesin family member 14
Synonyms: N-3 kinesin, D1Ertd367e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 381293
Homologene: 8916
Phldb2
Name: pleckstrin homology like domain, family B, member 2
Synonyms: LL5beta, LL5b, C820004H04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 208177
Homologene: 17100
Whamm
Name: WAS protein homolog associated with actin, golgi membranes and microtubules
Synonyms: Whdc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 434204
Homologene: 45851
Gm5499
Name: predicted pseudogene 5499
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 433144
Klk1b9
Name: kallikrein 1-related peptidase b9
Synonyms: mGk-9, Egfbp-3, Egfbp3, Klk9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 13648
HGNC: HGNC:6364
Homologene: 68141
Olfr204
Name: olfactory receptor 204
Synonyms: GA_x54KRFPKG5P-55529713-55528796, MOR182-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 258994
Homologene: 79425
Ebf4
Name: early B cell factor 4
Synonyms: Olf-1/EBF-like 4, O/E-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228598
Homologene: 65064
Iqca1l
Name: IQ motif containing with AAA domain 1 like
Synonyms: 4931409K22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231045
Homologene: 18602
Actr3b
Name: ARP3 actin-related protein 3B
Synonyms: ARP11, Arp3b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 242894
Homologene: 4180
Insyn2a
Name: inhibitory synaptic factor 2A
Synonyms: B830028B13Rik, Fam196a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 627214
Homologene: 85469
Nhsl2
Name: NHS-like 2
Synonyms: 1110062M06Rik, Gm10456
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 100042480
Homologene: 19759
Gm9913
Name: predicted gene 9913
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 71,267,605 bp
  • T to G, chromosome 1 at 136,519,645 bp
  • T to C, chromosome 2 at 98,663,852 bp
  • T to C, chromosome 2 at 122,514,414 bp
  • A to G, chromosome 2 at 125,506,539 bp
  • G to A, chromosome 2 at 130,306,499 bp
  • T to A, chromosome 2 at 155,249,945 bp
  • T to C, chromosome 2 at 166,955,016 bp
  • T to C, chromosome 3 at 64,134,632 bp
  • T to C, chromosome 3 at 116,647,917 bp
  • C to T, chromosome 3 at 144,968,253 bp
  • T to A, chromosome 4 at 43,640,182 bp
  • T to G, chromosome 4 at 59,213,922 bp
  • T to C, chromosome 4 at 94,569,805 bp
  • G to C, chromosome 5 at 24,546,666 bp
  • A to G, chromosome 5 at 25,822,442 bp
  • A to G, chromosome 5 at 45,522,478 bp
  • A to T, chromosome 5 at 129,129,105 bp
  • G to A, chromosome 7 at 16,237,424 bp
  • A to G, chromosome 7 at 43,978,500 bp
  • A to G, chromosome 7 at 56,137,243 bp
  • T to C, chromosome 7 at 79,752,493 bp
  • G to C, chromosome 7 at 81,571,784 bp
  • A to G, chromosome 7 at 134,918,021 bp
  • G to T, chromosome 9 at 21,845,754 bp
  • A to G, chromosome 9 at 78,458,028 bp
  • T to A, chromosome 11 at 3,503,124 bp
  • A to T, chromosome 11 at 19,011,254 bp
  • C to T, chromosome 11 at 62,867,513 bp
  • G to A, chromosome 11 at 73,776,640 bp
  • G to C, chromosome 11 at 74,843,110 bp
  • C to G, chromosome 12 at 84,875,720 bp
  • T to G, chromosome 12 at 89,260,416 bp
  • A to T, chromosome 13 at 93,048,927 bp
  • T to C, chromosome 14 at 20,653,617 bp
  • T to A, chromosome 14 at 28,513,183 bp
  • T to C, chromosome 15 at 90,227,936 bp
  • T to C, chromosome 16 at 45,825,010 bp
  • A to T, chromosome 16 at 59,314,726 bp
  • A to G, chromosome 16 at 87,488,877 bp
  • T to C, chromosome 16 at 91,386,001 bp
  • T to C, chromosome 17 at 87,078,886 bp
  • T to C, chromosome 18 at 31,967,184 bp
  • C to T, chromosome X at 102,077,595 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3078 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
040568-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.