Strain Name:
C57BL/6J-MtgxR3081Btlr/Mmmh
Stock Number:
040571-MU
Citation ID:
RRID:MMRRC_040571-MU
Other Names:
R3081 (G1), C57BL/6J-MtgxR3081Btlr
Major Collection:

Gene Information

Glt8d1
Name: glycosyltransferase 8 domain containing 1
Synonyms: 5430414N14Rik, 2410004H05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 76485
VEGA: 14
Homologene: 32720
Hdac5
Name: histone deacetylase 5
Synonyms: mHDA1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 15184
Homologene: 3995
Ssc4d
Name: scavenger receptor cysteine rich family, 4 domains
Synonyms: C330016E03Rik, Srcrb4d
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 109267
Homologene: 34137
Senp6
Name: SUMO/sentrin specific peptidase 6
Synonyms: 2810017C20Rik, E130319N12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 215351
Homologene: 9196
Dock6
Name: dedicator of cytokinesis 6
Synonyms: C330023D02Rik, 4931431C02Rik, 2410095B20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 319899
VEGA: 9
Homologene: 83291
Stip1
Name: stress-induced phosphoprotein 1
Synonyms: STI1, IEF SSP 3521, Hop, Hsp70/Hsp90 organizing protein, p60
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 20867
VEGA: 19
Homologene: 4965
Als2
Name: alsin Rho guanine nucleotide exchange factor
Synonyms: Als2cr6, Alsin, 3222402C23Rik, 9430073A21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 74018
HGNC: HGNC:443
Homologene: 23264
Zfp180
Name: zinc finger protein 180
Synonyms: D130011P11, 2310040I01Rik, HHZ168
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 210135
Homologene: 8306
Commd9
Name: COMM domain containing 9
Synonyms: 1810029F08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 76501
Homologene: 8584
Derl1
Name: Der1-like domain family, member 1
Synonyms: Derlin-1, 1110021N07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 67819
VEGA: 15
Homologene: 11483
Rxfp3
Name: relaxin family peptide receptor 3
Synonyms: Salpr, Rln3r1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 239336
Homologene: 9568
Dzip3
Name: DAZ interacting protein 3, zinc finger
Synonyms: 6430549P11Rik, 2A-HUB, 2310047C04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 224170
Homologene: 8771
Fbxl5
Name: F-box and leucine-rich repeat protein 5
Synonyms: Fir4, Fbl4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 242960
Homologene: 8129
Cfap77
Name: cilia and flagella associated protein 77
Synonyms: LOC329375, 1700101E01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 329375
Homologene: 45813
Cldn14
Name: claudin 14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 56173
HGNC: HGNC:2035
Homologene: 8115
Abcf3
Name: ATP-binding cassette, sub-family F (GCN20), member 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 27406
HGNC: HGNC:72
Homologene: 22784
Carm1
Name: coactivator-associated arginine methyltransferase 1
Synonyms: Prmt4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 59035
Homologene: 10990
Nol8
Name: nucleolar protein 8
Synonyms: 4921532D18Rik, 5730412B09Rik, D13Ertd548e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 70930
VEGA: 13
Homologene: 41210
Bcl9
Name: B cell CLL/lymphoma 9
Synonyms: A330041G23Rik, 2610202E01Rik, 8030475K17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 77578
HGNC: HGNC:1008
Homologene: 3191
Nmd3
Name: NMD3 ribosome export adaptor
Synonyms: C87860
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 97112
Homologene: 6127
Vps13a
Name: vacuolar protein sorting 13A
Synonyms: 4930543C13Rik, 4930516E05Rik, D330038K10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 271564
VEGA: 19
HGNC: HGNC:1908
Homologene: 22068
Dock2
Name: dedicator of cyto-kinesis 2
Synonyms: MBC, Hch, CED-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 94176
HGNC: HGNC:2988
Homologene: 37984
Lama2
Name: laminin, alpha 2
Synonyms: mer, merosin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 16773
HGNC: HGNC:6482
Homologene: 37306
Cfap70
Name: cilia and flagella associated protein 70
Synonyms: 5330402L21Rik, Ttc18
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 76670
Homologene: 17048
Slc22a4
Name: solute carrier family 22 (organic cation transporter), member 4
Synonyms: Octn1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 30805
Homologene: 81701
Tecta
Name: tectorin alpha
Synonyms: Tctna, [a]-tectorin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 21683
Homologene: 3955
Tmed4
Name: transmembrane p24 trafficking protein 4
Synonyms: 1110014L17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 103694
Homologene: 5308
Olfr901
Name: olfactory receptor 901
Synonyms: MOR162-8, GA_x6K02T2PVTD-32123032-32123967
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 258028
VEGA: 9
HGNC: null
Homologene: 79399
Phf11c
Name: PHD finger protein 11C
Synonyms: Gm6907
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 628705
Homologene: 87807
Olfr954
Name: olfactory receptor 954
Synonyms: MOR171-53, GA_x6K02T2PVTD-33158015-33158950, MOR171-42
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 258328
VEGA: 9
HGNC: null
Homologene: 71961
Ttc39d
Name: tetratricopeptide repeat domain 39D
Synonyms: 4930560E09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 67737
Homologene: 65053
Lrriq1
Name: leucine-rich repeats and IQ motif containing 1
Synonyms: LOC380658, 4930503E15Rik, Gm1557
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 74978
Homologene: 46007
Vmn2r88
Name: vomeronasal 2, receptor 88
Synonyms: V2r13, V2r3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 669149
HGNC: null
Homologene: 129606
Wnk4
Name: WNK lysine deficient protein kinase 4
Synonyms: Prkwnk4, 2010002J11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 69847
Homologene: 13020
Mgat3
Name: mannoside acetylglucosaminyltransferase 3
Synonyms: GnT-III, 1110038J12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 17309
VEGA: 15
HGNC: HGNC:7046
Homologene: 31088
Myo3b
Name: myosin IIIB
Synonyms: A430065P19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 329421
Homologene: 51393
Olfr389
Name: olfactory receptor 389
Synonyms: MOR135-6, GA_x6K02T2P1NL-3932085-3931147
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 259011
HGNC: null
Homologene: 85925
Evpl
Name: envoplakin
Synonyms: 210kDa protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 14027
HGNC: HGNC:3503
Homologene: 1506
Olfr870
Name: olfactory receptor 870
Synonyms: MOR141-1, GA_x6K02T2PVTD-13912679-13911744
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 57251
HGNC: null
Homologene: 138319
Tsen54
Name: tRNA splicing endonuclease subunit 54
Synonyms: 0610034P02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 76265
Homologene: 35476
Abcc3
Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 3
Synonyms: MRP3, 1700019L09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 76408
HGNC: HGNC:54
Homologene: 68364
Dixdc1
Name: DIX domain containing 1
Synonyms: 4930563F16Rik, Ccd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 330938
Homologene: 82369
Cdkn2aip
Name: CDKN2A interacting protein
Synonyms: 4921511I16Rik, CARF
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 70925
Homologene: 9752
Fam75d3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
Coro6
Name: coronin 6
Synonyms: clipin E
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 216961
Homologene: 104099
Rusc1
Name: RUN and SH3 domain containing 1
Synonyms: 2210403N08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 72296
Homologene: 75028
Nfxl1
Name: nuclear transcription factor, X-box binding-like 1
Synonyms: LOC381696, TCF9, 1700012H24Rik, D430033A06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 100978
Homologene: 26752
Arhgap45
Name: Rho GTPase activating protein 45
Synonyms: Hmha1, 6330406L22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 70719
Homologene: 69120
Fastkd3
Name: FAST kinase domains 3
Synonyms: 2310010B21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 69577
VEGA: 13
Homologene: 11457
Mylk2
Name: myosin, light polypeptide kinase 2, skeletal muscle
Synonyms: 9830004H17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228785
Homologene: 13223
AC159899.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
Rasl11a
Name: RAS-like, family 11, member A
Synonyms: 1110065D03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 68895
Homologene: 45783
Gpr25
Name: G protein-coupled receptor 25
Synonyms: LOC383563
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 383563
HGNC: HGNC:4480
Homologene: 3872
Efcab9
Name: EF-hand calcium binding domain 9
Synonyms: 1700007I06Rik, 4930403C08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 69306
Homologene: 12309
Tmem255b
Name: transmembrane protein 255B
Synonyms: LOC272465, Fam70b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 272465
Homologene: 18804
Asl
Name: argininosuccinate lyase
Synonyms: 2510006M18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 109900
HGNC: HGNC:746
Homologene: 32
Gm10260
Name: predicted gene 10260
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 100039740
VEGA: 13
HGNC: null
Homologene: null
Aamdc
Name: adipogenesis associated Mth938 domain containing
Synonyms: 1810020D17Rik, 1810037D19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 66273
Homologene: 11658
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 59,187,349 bp
  • A to C, chromosome 1 at 136,259,885 bp
  • T to A, chromosome 2 at 28,962,650 bp
  • A to C, chromosome 2 at 70,256,583 bp
  • G to A, chromosome 2 at 101,886,331 bp
  • A to G, chromosome 2 at 152,919,354 bp
  • A to G, chromosome 3 at 69,724,399 bp
  • A to G, chromosome 3 at 89,091,723 bp
  • A to T, chromosome 3 at 97,205,673 bp
  • A to G, chromosome 5 at 43,750,880 bp
  • C to T, chromosome 5 at 72,529,035 bp
  • T to C, chromosome 5 at 130,013,404 bp
  • T to C, chromosome 5 at 135,965,724 bp
  • G to T, chromosome 5 at 146,847,303 bp
  • A to T, chromosome 7 at 24,105,503 bp
  • T to A, chromosome 7 at 97,565,225 bp
  • T to A, chromosome 8 at 13,451,048 bp
  • T to C, chromosome 8 at 47,711,497 bp
  • T to C, chromosome 8 at 107,262,837 bp
  • C to A, chromosome 9 at 20,170,765 bp
  • C to A, chromosome 9 at 21,579,396 bp
  • A to G, chromosome 9 at 21,839,200 bp
  • T to A, chromosome 9 at 38,431,056 bp
  • G to A, chromosome 9 at 39,461,930 bp
  • A to T, chromosome 9 at 42,377,994 bp
  • G to A, chromosome 9 at 50,710,959 bp
  • G to A, chromosome 9 at 80,143,842 bp
  • A to G, chromosome 9 at 99,232,474 bp
  • C to T, chromosome 10 at 27,001,235 bp
  • G to A, chromosome 10 at 80,026,447 bp
  • T to A, chromosome 10 at 103,144,889 bp
  • T to C, chromosome 11 at 6,274,151 bp
  • T to C, chromosome 11 at 32,523,689 bp
  • T to A, chromosome 11 at 34,231,610 bp
  • A to G, chromosome 11 at 54,007,789 bp
  • A to T, chromosome 11 at 73,777,225 bp
  • T to C, chromosome 11 at 77,468,912 bp
  • T to A, chromosome 11 at 94,356,976 bp
  • A to G, chromosome 11 at 101,276,891 bp
  • A to T, chromosome 11 at 102,205,610 bp
  • T to A, chromosome 11 at 115,820,164 bp
  • T to C, chromosome 11 at 116,220,852 bp
  • C to T, chromosome 13 at 49,678,392 bp
  • T to C, chromosome 13 at 59,703,093 bp
  • T to C, chromosome 13 at 68,584,868 bp
  • A to G, chromosome 14 at 20,420,762 bp
  • T to C, chromosome 14 at 31,006,660 bp
  • A to G, chromosome 14 at 51,418,632 bp
  • A to G, chromosome 14 at 59,381,484 bp
  • T to C, chromosome 15 at 11,037,217 bp
  • C to A, chromosome 15 at 57,875,611 bp
  • A to G, chromosome 15 at 80,211,854 bp
  • T to A, chromosome 16 at 20,559,364 bp
  • T to C, chromosome 16 at 48,927,558 bp
  • T to C, chromosome 16 at 93,919,304 bp
  • A to G, chromosome 17 at 80,217,553 bp
  • C to T, chromosome 19 at 7,035,648 bp
  • G to T, chromosome 19 at 16,664,737 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3081 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040571-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.