Strain Name:
C57BL/6J-MtgxR3106Btlr/Mmmh
Stock Number:
040580-MU
Citation ID:
RRID:MMRRC_040580-MU
Other Names:
R3106 (G1), C57BL/6J-MtgxR3106Btlr
Major Collection:

Gene Information

Smco3
Name: single-pass membrane protein with coiled-coil domains 3
Synonyms: C030030A07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 654818
Homologene: 79087
Grm1
Name: glutamate receptor, metabotropic 1
Synonyms: rcw, nmf373, mGluR1, Grm1, Gprc1a, 4930455H15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 14816
HGNC: HGNC:4593
Homologene: 649
Sparcl1
Name: SPARC-like 1
Synonyms: Ecm2, Sc1, hevin, mast9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 13602
Homologene: 3438
Ctnnal1
Name: catenin (cadherin associated protein), alpha-like 1
Synonyms: Catnal1, ACRP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 54366
HGNC: HGNC:2512
Homologene: 2815
Plekha7
Name: pleckstrin homology domain containing, family A member 7
Synonyms: A430081P20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233765
Homologene: 52172
Nphs1
Name: nephrosis 1, nephrin
Synonyms: nephrin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 54631
HGNC: HGNC:7908
Homologene: 20974
Tkfc
Name: triokinase, FMN cyclase
Synonyms: Dak
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 225913
VEGA: 19
Homologene: 56710
Trp53bp1
Name: transformation related protein 53 binding protein 1
Synonyms: 53BP1, p53BP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 27223
Homologene: 4137
Lemd2
Name: LEM domain containing 2
Synonyms: NET25, Lem2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 224640
VEGA: 17
Homologene: 17136
Baz2a
Name: bromodomain adjacent to zinc finger domain, 2A
Synonyms: Walp3, Tip5, C030005G16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 116848
VEGA: 10
HGNC: HGNC:962
Homologene: 8393
Atp5c1
Name: ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
Synonyms: F1 gamma, 1700094F02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 11949
HGNC: HGNC:833
Homologene: 3792
Urb1
Name: URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
Synonyms: 4921511H13Rik, 5730405K23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 207932
Homologene: 45941
Ccdc191
Name: coiled-coil domain containing 191
Synonyms: 2610015P09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 212153
Homologene: 19484
Ezh1
Name: enhancer of zeste 1 polycomb repressive complex 2 subunit
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 14055
HGNC: HGNC:3526
Homologene: 20458
Plekhg5
Name: pleckstrin homology domain containing, family G (with RhoGef domain) member 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 269608
Homologene: 10768
Ptprj
Name: protein tyrosine phosphatase, receptor type, J
Synonyms: Byp, CD148, DEP-1, RPTPJ, Scc-1, Scc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 19271
HGNC: HGNC:9673
Homologene: 2130
Galnt4
Name: polypeptide N-acetylgalactosaminyltransferase 4
Synonyms: ppGaNTase-T4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 14426
HGNC: HGNC:4126
Homologene: 74511
Pan3
Name: PAN3 poly(A) specific ribonuclease subunit
Synonyms: A430027N15Rik, 2700050F09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 72587
Homologene: 6372
Pld3
Name: phospholipase D family, member 3
Synonyms: Sam-9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 18807
Homologene: 7893
Ermard
Name: ER membrane associated RNA degradation
Synonyms: 2410011O22Rik, 2210404J11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 381062
Homologene: 19936
Hist1h1c
Name: histone cluster 1, H1c
Synonyms: H1c, 0610008C09Rik, H1f2, H1.2, H1var1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 50708
HGNC: HGNC:4716
Homologene: 68455
Emc10
Name: ER membrane protein complex subunit 10
Synonyms: Mirta22, 5430410O10Rik, 2310044H10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 69683
Homologene: 18036
Btf3
Name: basic transcription factor 3
Synonyms: 1700054E11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 218490
HGNC: HGNC:1125
Homologene: 37453
Mnd1
Name: meiotic nuclear divisions 1
Synonyms: 2610034E18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 76915
Homologene: 5890
Tmem51
Name: transmembrane protein 51
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 214359
Homologene: 9966
Ccdc184
Name: coiled-coil domain containing 184
Synonyms: AI836003
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 239650
VEGA: 15
Homologene: 18612
Adarb1
Name: adenosine deaminase, RNA-specific, B1
Synonyms: RED1, 1700057H01Rik, D10Bwg0447e, ADAR2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 110532
HGNC: HGNC:226
Homologene: 8280
Wdr19
Name: WD repeat domain 19
Synonyms: C330027H04Rik, Ift144, DYF2, D330023L08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 213081
Homologene: 11842
Stradb
Name: STE20-related kinase adaptor beta
Synonyms: Als2cr2, PRO1038, D1Ucla2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 227154
Homologene: 10237
Dgkg
Name: diacylglycerol kinase, gamma
Synonyms: Dagk3, E430001K23Rik, 2900055E17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 110197
HGNC: HGNC:2853
Homologene: 1029
Col6a3
Name: collagen, type VI, alpha 3
Synonyms: Col6a-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 12835
HGNC: HGNC:2213
Homologene: 37917
Abca15
Name: ATP-binding cassette, sub-family A (ABC1), member 15
Synonyms: 4930500I12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 320631
Homologene: 87255
Sfmbt1
Name: Scm-like with four mbt domains 1
Synonyms: 9330180L21Rik, 4930442N21Rik, Smr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 54650
Homologene: 9472
Lrrd1
Name: leucine rich repeats and death domain containing 1
Synonyms: 4932412H11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 242838
Homologene: 18247
Cntln
Name: centlein, centrosomal protein
Synonyms: B430108F07Rik, D530005L17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 338349
Homologene: 9805
Dennd3
Name: DENN/MADD domain containing 3
Synonyms: E030003N15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 105841
Homologene: 28254
Hnf4g
Name: hepatocyte nuclear factor 4, gamma
Synonyms: NR2A2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 30942
HGNC: HGNC:5026
Homologene: 37886
Fam187b
Name: family with sequence similarity 187, member B
Synonyms: 1700020B09Rik, Tmem162
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 76415
Homologene: 138431
Adam22
Name: a disintegrin and metallopeptidase domain 22
Synonyms: 2900022I03Rik, MDC2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 11496
HGNC: HGNC:201
Homologene: 37898
Olfr1136
Name: olfactory receptor 1136
Synonyms: MOR177-3, GA_x6K02T2Q125-49193051-49192119
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258653
Homologene: 74193
Dzip1l
Name: DAZ interacting protein 1-like
Synonyms: 2610524A10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 72507
Homologene: 12466
Il1rap
Name: interleukin 1 receptor accessory protein
Synonyms: IL-1R AcP, IL-1RAcP, 6430709H04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 16180
HGNC: HGNC:5995
Homologene: 1643
Tmigd1
Name: transmembrane and immunoglobulin domain containing 1
Synonyms: 2010002A20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 66601
Homologene: 41641
Clip2
Name: CAP-GLY domain containing linker protein 2
Synonyms: CLIP-115, Cyln2, WSCR4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 269713
HGNC: HGNC:2586
Homologene: 20718
Tsga10
Name: testis specific 10
Synonyms: Mtsga10, 4933432N21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 211484
Homologene: 23531
Adamts17
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 17
Synonyms: AU023434
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233332
Homologene: 16373
Gm13119
Name: predicted gene 13119
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 433779
Homologene: 83161
Coro2b
Name: coronin, actin binding protein, 2B
Synonyms: E130012P22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235431
HGNC: HGNC:2256
Homologene: 21228
Ceacam5
Name: carcinoembryonic antigen-related cell adhesion molecule 5
Synonyms: 1600029H12Rik, Psg30
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 73250
Homologene: 115938
FP885536.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
Tm4sf4
Name: transmembrane 4 superfamily member 4
Synonyms: il-TMP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229302
Homologene: 3393
Tmem212
Name: transmembrane protein 212
Synonyms: E030011K20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 208613
Homologene: 28471
Sbspon
Name: somatomedin B and thrombospondin, type 1 domain containing
Synonyms: LOC226866, Gm106
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 226866
Homologene: 45950
Sppl2b
Name: signal peptide peptidase like 2B
Synonyms: 3110056O03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 73218
VEGA: 10
Homologene: 10605
Ptpn20
Name: protein tyrosine phosphatase, non-receptor type 20
Synonyms: typ
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 19256
VEGA: 14
Homologene: 74905
Osgep
Name: O-sialoglycoprotein endopeptidase
Synonyms: PRSMG1, GCPL-1, 1500019L24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 66246
Homologene: 6395
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 15,892,582 bp
  • G to A, chromosome 1 at 37,801,791 bp
  • C to A, chromosome 1 at 58,992,291 bp
  • T to C, chromosome 1 at 90,816,302 bp
  • A to G, chromosome 2 at 10,063,465 bp
  • T to C, chromosome 2 at 87,693,505 bp
  • T to A, chromosome 2 at 90,440,631 bp
  • A to G, chromosome 2 at 121,236,652 bp
  • T to G, chromosome 3 at 3,652,856 bp
  • T to C, chromosome 3 at 27,884,870 bp
  • C to T, chromosome 3 at 57,437,622 bp
  • C to A, chromosome 3 at 84,134,109 bp
  • G to A, chromosome 4 at 56,813,246 bp
  • C to T, chromosome 4 at 84,957,169 bp
  • T to C, chromosome 4 at 142,037,724 bp
  • T to C, chromosome 4 at 144,361,676 bp
  • C to T, chromosome 4 at 152,112,178 bp
  • T to A, chromosome 4 at 156,333,435 bp
  • A to G, chromosome 5 at 3,858,839 bp
  • A to G, chromosome 5 at 8,117,583 bp
  • T to C, chromosome 5 at 65,202,623 bp
  • T to C, chromosome 5 at 104,093,337 bp
  • T to C, chromosome 5 at 134,523,064 bp
  • T to C, chromosome 5 at 147,539,379 bp
  • T to C, chromosome 6 at 136,831,180 bp
  • T to C, chromosome 7 at 17,747,323 bp
  • A to G, chromosome 7 at 27,535,787 bp
  • C to A, chromosome 7 at 30,467,540 bp
  • A to G, chromosome 7 at 30,977,240 bp
  • G to A, chromosome 7 at 44,493,192 bp
  • T to A, chromosome 7 at 67,125,072 bp
  • C to T, chromosome 7 at 116,164,404 bp
  • A to T, chromosome 7 at 120,396,633 bp
  • T to C, chromosome 9 at 62,429,212 bp
  • A to T, chromosome 9 at 99,642,572 bp
  • A to G, chromosome 9 at 99,647,121 bp
  • A to G, chromosome 10 at 11,079,857 bp
  • C to A, chromosome 10 at 77,321,757 bp
  • A to G, chromosome 10 at 80,867,491 bp
  • T to C, chromosome 10 at 99,109,381 bp
  • AGCGGCGGTACTTGCGGG to AG, chromosome 10 at 128,125,077 bp
  • A to G, chromosome 11 at 76,910,298 bp
  • A to C, chromosome 11 at 101,195,642 bp
  • G to T, chromosome 13 at 23,738,900 bp
  • T to G, chromosome 13 at 98,310,988 bp
  • G to A, chromosome 14 at 30,817,796 bp
  • A to G, chromosome 14 at 33,612,296 bp
  • T to C, chromosome 14 at 50,916,829 bp
  • C to A, chromosome 15 at 73,565,124 bp
  • G to T, chromosome 15 at 98,168,601 bp
  • T to A, chromosome 16 at 22,575,341 bp
  • A to G, chromosome 16 at 26,722,752 bp
  • T to C, chromosome 16 at 43,931,210 bp
  • C to T, chromosome 16 at 90,795,443 bp
  • C to T, chromosome 17 at 15,061,191 bp
  • C to A, chromosome 17 at 27,201,670 bp
  • G to T, chromosome 19 at 10,596,993 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3106 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040580-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.