Strain Name:
C57BL/6J-MtgxR3155Btlr/Mmmh
Stock Number:
040606-MU
Citation ID:
RRID:MMRRC_040606-MU
Other Names:
R3155 (G1), C57BL/6J-MtgxR3155Btlr
Major Collection:

Gene Information

Rlf
Name: rearranged L-myc fusion sequence
Synonyms: MommeD8, 9230110M18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 109263
Homologene: 8243
Stk4
Name: serine/threonine kinase 4
Synonyms: Ysk3, Kas-2, sterile 20-like kinase 1, Mst1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 58231
Homologene: 55965
Taf15
Name: TATA-box binding protein associated factor 15
Synonyms: Taf2n, 68kDa, TAFII68, 2610111C21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 70439
Homologene: 131088
Ahctf1
Name: AT hook containing transcription factor 1
Synonyms: 6230412P20Rik, Elys
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 226747
Homologene: 9142
Ccdc14
Name: coiled-coil domain containing 14
Synonyms: G630039H03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 239839
VEGA: 16
Homologene: 32549
Pawr
Name: PRKC, apoptosis, WT1, regulator
Synonyms: Par4, 2310001G03Rik, Par-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 114774
VEGA: 10
HGNC: HGNC:8614
Homologene: 1940
Rif1
Name: replication timing regulatory factor 1
Synonyms: D2Ertd145e, 6530403D07Rik, 5730435J01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 51869
Homologene: 41231
Dmbt1
Name: deleted in malignant brain tumors 1
Synonyms: gp300, Crpd, hensin, ebnerin, CRP-[a], vomeroglandin, CRP-[b], MUCLIN
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 12945
HGNC: HGNC:2926
Homologene: 68990
Aco1
Name: aconitase 1
Synonyms: Irp1, Irebp, Aco-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 11428
HGNC: HGNC:117
Homologene: 1657
Sema6a
Name: sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
Synonyms: Sema6A-1, sema, A730020P05Rik, VIa, Semaq
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 20358
Homologene: 32426
Slc15a4
Name: solute carrier family 15, member 4
Synonyms: C130069N12Rik, PTR4, PHT1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 100561
Homologene: 26432
Fbxw11
Name: F-box and WD-40 domain protein 11
Synonyms: BTRC2, BTRCP2, 2310065A07Rik, Fbxw1b, HOS
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 103583
Homologene: 76444
Fancm
Name: Fanconi anemia, complementation group M
Synonyms: C730036B14Rik, D12Ertd364e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 104806
VEGA: 12
Homologene: 35378
Rbp3
Name: retinol binding protein 3, interstitial
Synonyms: Rbp-3, Irbp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 19661
VEGA: 14
HGNC: HGNC:9921
Homologene: 9261
Anxa9
Name: annexin A9
Synonyms: 2310069F17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 71790
HGNC: HGNC:547
Homologene: 2643
Myh6
Name: myosin, heavy polypeptide 6, cardiac muscle, alpha
Synonyms: alphaMHC, alpha myosin, Myhca, alpha cardiac MHC, A830009F23Rik, Myhc-a, cardiomyopathy, hypertrophic 1, alpha-MHC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 17888
HGNC: HGNC:7576
Homologene: 124414
Gbp5
Name: guanylate binding protein 5
Synonyms: 5330409J06Rik, Gbp5a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229898
Homologene: 14183
Cdhr3
Name: cadherin-related family member 3
Synonyms: 1110049B09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 68764
VEGA: 12
Homologene: 45146
Rin2
Name: Ras and Rab interactor 2
Synonyms: 4632403N06Rik, 2010003K16Rik, RASSF4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 74030
Homologene: 32430
Ahnak
Name: AHNAK nucleoprotein (desmoyokin)
Synonyms: 1110004P15Rik, 2310047C17Rik, DY6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 66395
VEGA: 19
HGNC: HGNC:347
Homologene: 67425
Kdr
Name: kinase insert domain protein receptor
Synonyms: VEGF receptor-2, vascular endothelial growth factor receptor- 2, Flk-1, orv, Flk1, VEGFR-2, VEGFR2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 16542
HGNC: HGNC:6307
Homologene: 55639
Npc1l1
Name: NPC1 like intracellular cholesterol transporter 1
Synonyms: Niemann-Pick disease, type C1, 9130221N23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 237636
HGNC: HGNC:7898
Homologene: 56585
Klhdc7a
Name: kelch domain containing 7A
Synonyms: B230308G19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 242721
Homologene: 17567
Ppp2r3a
Name: protein phosphatase 2, regulatory subunit B'', alpha
Synonyms: 3222402P14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235542
HGNC: HGNC:9307
Homologene: 20595
Urgcp
Name: upregulator of cell proliferation
Synonyms: 2010005J08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 72046
Homologene: 69243
4933407L21Rik
Name: RIKEN cDNA 4933407L21 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 71141
Cfap61
Name: cilia and flagella associated protein 61
Synonyms: 4930529M08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 78774
Adh1
Name: alcohol dehydrogenase 1 (class I)
Synonyms: Adh1tl, class I alcohol dehydrogenase, Adh-1-t, Adh1-e, Adh-1, Adh-1t, Adh-1e, ADH-AA, Adh1-t
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 11522
Homologene: 73888
Cyp2d9
Name: cytochrome P450, family 2, subfamily d, polypeptide 9
Synonyms: Cyp2d, testosterone 16alpha-hydroxylase, P450-2D
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 13105
VEGA: 15
Homologene: 86099
Gm6871
Name: predicted gene 6871
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 102642386
Rusc1
Name: RUN and SH3 domain containing 1
Synonyms: 2210403N08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 72296
Homologene: 75028
Vmn2r76
Name: vomeronasal 2, receptor 76
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 675969
Homologene: 104330
Aebp1
Name: AE binding protein 1
Synonyms: ACLP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 11568
HGNC: HGNC:303
Homologene: 878
Fut2
Name: fucosyltransferase 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 14344
HGNC: HGNC:4013
Homologene: 10325
AC111097.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
Olfr726
Name: olfactory receptor 726
Synonyms: GA_x6K02T2PMLR-5775299-5774334, MOR246-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 258313
Homologene: 44957
Olfr895
Name: olfactory receptor 895
Synonyms: GA_x6K02T2PVTD-31962461-31963411, MOR170-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 258875
Homologene: 74253
H2-Eb1
Name: histocompatibility 2, class II antigen E beta
Synonyms: H-2Eb, Ia-4, Ia4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 14969
HGNC: HGNC:4953
Homologene: 101524
Zfp324
Name: zinc finger protein 324
Synonyms: ZF5128, D430030K24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 243834
Homologene: 8648
Map10
Name: microtubule-associated protein 10
Synonyms: 4933403G14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 74393
Homologene: 10416
Glrp1
Name: glutamine repeat protein 1
Synonyms: GRP-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 14659
Cldn34a
Name: claudin 34A
Synonyms: Gm7157
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
Alteration at locus: Chemically Induced
NCBI: 635396
VEGA: X
Homologene: 120374
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 85,931,383 bp
  • C to A, chromosome 1 at 88,503,254 bp
  • G to A, chromosome 1 at 179,755,583 bp
  • GCCACCA to GCCA, chromosome 2 at 52,110,324 bp
  • A to G, chromosome 2 at 145,860,851 bp
  • T to C, chromosome 2 at 146,128,943 bp
  • T to A, chromosome 2 at 164,151,743 bp
  • T to C, chromosome 3 at 89,091,731 bp
  • A to T, chromosome 3 at 95,302,405 bp
  • A to G, chromosome 3 at 129,791,395 bp
  • A to G, chromosome 3 at 138,280,489 bp
  • T to C, chromosome 3 at 142,503,127 bp
  • T to C, chromosome 4 at 40,182,915 bp
  • A to G, chromosome 4 at 121,149,332 bp
  • A to G, chromosome 4 at 139,967,189 bp
  • T to A, chromosome 5 at 75,968,405 bp
  • A to G, chromosome 5 at 127,604,536 bp
  • G to A, chromosome 7 at 12,968,890 bp
  • T to C, chromosome 7 at 41,573,655 bp
  • A to T, chromosome 7 at 45,650,667 bp
  • T to C, chromosome 7 at 86,225,751 bp
  • T to A, chromosome 7 at 131,050,157 bp
  • A to T, chromosome 8 at 125,671,574 bp
  • T to A, chromosome 9 at 38,268,540 bp
  • T to C, chromosome 9 at 101,212,360 bp
  • A to G, chromosome 10 at 108,409,509 bp
  • A to T, chromosome 11 at 5,716,327 bp
  • A to G, chromosome 11 at 5,871,425 bp
  • A to C, chromosome 11 at 6,221,840 bp
  • A to G, chromosome 11 at 32,739,244 bp
  • T to A, chromosome 11 at 83,502,773 bp
  • T to A, chromosome 12 at 33,049,153 bp
  • T to C, chromosome 12 at 65,116,421 bp
  • A to T, chromosome 14 at 33,957,114 bp
  • T to C, chromosome 14 at 50,084,525 bp
  • A to G, chromosome 14 at 54,944,668 bp
  • T to A, chromosome 15 at 82,452,642 bp
  • A to G, chromosome 16 at 34,723,852 bp
  • C to A, chromosome 17 at 34,314,374 bp
  • T to A, chromosome 18 at 47,306,346 bp
  • A to T, chromosome 19 at 9,010,177 bp
  • C to T, chromosome X at 152,563,844 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3155 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040606-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.