Strain Name:
C57BL/6J-MtgxR3161Btlr/Mmmh
Stock Number:
040612-MU
Citation ID:
RRID:MMRRC_040612-MU
Other Names:
R3161 (G1), C57BL/6J-MtgxR3161Btlr
Major Collection:

Gene Information

Adcy9
Name: adenylate cyclase 9
Synonyms: D16Wsu65e, ACtp10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 11515
HGNC: HGNC:240
Homologene: 868
Pkp4
Name: plakophilin 4
Synonyms: p0071, Armrp, 5031422I09Rik, 9430019K17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227937
HGNC: HGNC:9026
Homologene: 2689
Rai14
Name: retinoic acid induced 14
Synonyms: 1700020L11Rik, Ankycorbin, Norpeg, 1700008J19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 75646
VEGA: 15
Homologene: 9199
Nup155
Name: nucleoporin 155
Synonyms: D930027M19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 170762
VEGA: 15
HGNC: HGNC:8063
Homologene: 43155
Camk1g
Name: calcium/calmodulin-dependent protein kinase I gamma
Synonyms: CLICK-III, CaMKIgamma
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 215303
Homologene: 48706
Dlg4
Name: discs large MAGUK scaffold protein 4
Synonyms: SAP90, PSD-95, SAP90A, PSD95, Dlgh4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 13385
HGNC: HGNC:2903
Homologene: 1047
Yeats2
Name: YEATS domain containing 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 208146
VEGA: 16
Homologene: 9967
Adgrl2
Name: adhesion G protein-coupled receptor L2
Synonyms: Lphh1, Lec1, Lphn2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 99633
Homologene: 22712
Ptprg
Name: protein tyrosine phosphatase, receptor type, G
Synonyms: 5430405N12Rik, RPTPgamma
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 19270
HGNC: HGNC:9671
Homologene: 2129
Daam1
Name: dishevelled associated activator of morphogenesis 1
Synonyms: 1700066F09Rik, 2310028E21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 208846
VEGA: 12
Homologene: 36635
Bptf
Name: bromodomain PHD finger transcription factor
Synonyms: 9430093H17Rik, Falz
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 207165
HGNC: HGNC:3581
Homologene: 114397
Wls
Name: wntless WNT ligand secretion mediator
Synonyms: 5031439A09Rik, Gpr177
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 68151
Homologene: 11779
Copa
Name: coatomer protein complex subunit alpha
Synonyms: xenin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12847
HGNC: HGNC:2230
Homologene: 3218
Myo9a
Name: myosin IXa
Synonyms: 4732465J09Rik, C130068I12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 270163
HGNC: HGNC:7608
Homologene: 21371
Ipo9
Name: importin 9
Synonyms: 0710008K06Rik, Imp9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226432
Homologene: 5874
Psap
Name: prosaposin
Synonyms: SGP-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 19156
HGNC: HGNC:9498
Homologene: 37680
Fbf1
Name: Fas (TNFRSF6) binding factor 1
Synonyms: 1110033G01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217335
Homologene: 16531
Zfp868
Name: zinc finger protein 868
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234362
Homologene: 74376
Hnrnpu
Name: heterogeneous nuclear ribonucleoprotein U
Synonyms: scaffold attachment factor A, Sp120, Hnrpu
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 51810
HGNC: HGNC:5048
Homologene: 22991
Garnl3
Name: GTPase activating RANGAP domain-like 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 99326
Homologene: 13003
Atad2b
Name: ATPase family, AAA domain containing 2B
Synonyms: 1110014E10Rik, D530031C13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 320817
VEGA: 12
Homologene: 86351
Gpr152
Name: G protein-coupled receptor 152
Synonyms: LOC269053, A930009H15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 269053
VEGA: 19
Homologene: 35474
1700125H20Rik
Name: RIKEN cDNA 1700125H20 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 73634
Homologene: 18763
Ppil3
Name: peptidylprolyl isomerase (cyclophilin)-like 3
Synonyms: 2510026K04Rik, Cyp10l, 2310076N22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 70225
HGNC: HGNC:9262
Homologene: 41717
Ttn
Name: titin
Synonyms: connectin, L56, mdm, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, shru
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22138
Homologene: 130650
G6pc2
Name: glucose-6-phosphatase, catalytic, 2
Synonyms: IGRP, islet specific glucose-6-phosphatase, G6pc-rs
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14378
Homologene: 41423
Vmn2r115
Name: vomeronasal 2, receptor 115
Synonyms: EG638102, V2Rp4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 638102
Homologene: 86604
Plcb1
Name: phospholipase C, beta 1
Synonyms: 3110043I21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 18795
Homologene: 22876
Ciz1
Name: CDKN1A interacting zinc finger protein 1
Synonyms: 2900056O04Rik, 0610038H21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 68379
Homologene: 8112
Aox2
Name: aldehyde oxidase 2
Synonyms: Aox3l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 213043
Homologene: 84622
Olfr213
Name: olfactory receptor 213
Synonyms: GA_x54KRFPKN04-58174409-58175392, MOR119-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 258020
Homologene: 74186
Topaz1
Name: testis and ovary specific PAZ domain containing 1
Synonyms: Gm9524
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 671232
VEGA: 9
Homologene: 19835
0610040J01Rik
Name: RIKEN cDNA 0610040J01 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 76261
Homologene: 49537
Zfp598
Name: zinc finger protein 598
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 213753
VEGA: 17
Homologene: 5672
Vmn2r117
Name: vomeronasal 2, receptor 117
Synonyms: EG619788, V2Rp6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 619788
Homologene: 86604
Amer2
Name: APC membrane recruitment 2
Synonyms: 2600011E07Rik, Amer2, Fam123a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 72125
VEGA: 14
Homologene: 45141
Olfr262
Name: olfactory receptor 262
Synonyms: GA_x6K02T2N4A9-18144-19082, MOR214-1, MOR214-9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 258683
Dapk2
Name: death-associated protein kinase 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 13143
HGNC: HGNC:2675
Homologene: 74940
Crabp2
Name: cellular retinoic acid binding protein II
Synonyms: Crabp-2, CrabpII
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 12904
HGNC: HGNC:2339
Homologene: 1415
Olfr739
Name: olfactory receptor 739
Synonyms: GA_x6K02T2PMLR-6121675-6122604, MOR106-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 258663
Homologene: 121549
Cyp27b1
Name: cytochrome P450, family 27, subfamily b, polypeptide 1
Synonyms: 1alpha(OH)ase, P450VD1alpha, 25-hydroxyvitamin D3 1alpha-hydroxylase, 25(OH)D 1alpha-hydroxylase, VddrI, P450c1, Cyp27b, Vddr, Vdd1, Pddr, Cyp1, Cp2b, Cyp40
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 13115
HGNC: HGNC:2606
Homologene: 37139
Phyh
Name: phytanoyl-CoA hydroxylase
Synonyms: Lnap1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 16922
HGNC: HGNC:8940
Homologene: 4530
Caps2
Name: calcyphosphine 2
Synonyms: D630005B03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 353025
Homologene: 72278
Gm7337
Name: predicted gene 7337
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 654494
Sult2a4
Name: sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 4
Synonyms: Gm5584
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 434121
Homologene: 37741
Olfr1351
Name: olfactory receptor 1351
Synonyms: GA_x6K02T2QGN0-2794907-2793948, MOR139-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 259042
Homologene: 133668
Disp1
Name: dispatched RND transporter family member 1
Synonyms: DispA, 1190008H24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 68897
Homologene: 14133
Vstm5
Name: V-set and transmembrane domain containing 5
Synonyms: 2200002K05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 69137
VEGA: 9
Homologene: 45982
Tacr2
Name: tachykinin receptor 2
Synonyms: Tac2r
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 21337
VEGA: 10
Homologene: 55548
Wipf1
Name: WAS/WASL interacting protein family, member 1
Synonyms: WIP, D2Ertd120e, Waspip
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 215280
Homologene: 86891
Mmp7
Name: matrix metallopeptidase 7
Synonyms: matrilysin, MAT
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 17393
HGNC: HGNC:7174
Homologene: 37619
Rps2
Name: ribosomal protein S2
Synonyms: Rps2, Llrep3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 16898
Homologene: 37714
Prokr1
Name: prokineticin receptor 1
Synonyms: Pkr1, EG-VEGFR1, Gpr73
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 58182
HGNC: HGNC:4524
Homologene: 10968
1700066M21Rik
Name: RIKEN cDNA 1700066M21 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 73467
Homologene: 13624
Fen1
Name: flap structure specific endonuclease 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 14156
HGNC: HGNC:3650
Homologene: 3034
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 57,383,075 bp
  • G to T, chromosome 1 at 58,304,438 bp
  • A to T, chromosome 1 at 58,434,414 bp
  • T to C, chromosome 1 at 135,409,476 bp
  • T to A, chromosome 1 at 172,091,233 bp
  • T to C, chromosome 1 at 178,331,125 bp
  • T to C, chromosome 1 at 183,087,242 bp
  • T to C, chromosome 1 at 193,359,807 bp
  • T to A, chromosome 2 at 4,937,671 bp
  • A to G, chromosome 2 at 32,370,063 bp
  • A to T, chromosome 2 at 33,034,711 bp
  • G to T, chromosome 2 at 59,308,105 bp
  • A to G, chromosome 2 at 69,220,112 bp
  • C to T, chromosome 2 at 73,434,949 bp
  • A to G, chromosome 2 at 76,833,237 bp
  • A to T, chromosome 2 at 135,335,482 bp
  • A to T, chromosome 3 at 87,952,177 bp
  • G to A, chromosome 3 at 148,817,551 bp
  • G to T, chromosome 3 at 159,897,436 bp
  • T to C, chromosome 5 at 63,896,490 bp
  • A to C, chromosome 5 at 87,851,557 bp
  • C to T, chromosome 6 at 87,588,431 bp
  • C to T, chromosome 6 at 116,540,846 bp
  • T to C, chromosome 7 at 13,989,471 bp
  • A to G, chromosome 8 at 69,612,085 bp
  • T to A, chromosome 9 at 7,696,189 bp
  • T to G, chromosome 9 at 15,257,298 bp
  • C to T, chromosome 9 at 59,832,315 bp
  • T to G, chromosome 9 at 66,254,611 bp
  • T to C, chromosome 9 at 122,749,381 bp
  • T to C, chromosome 10 at 60,277,753 bp
  • A to G, chromosome 10 at 62,265,245 bp
  • C to A, chromosome 10 at 79,017,604 bp
  • T to A, chromosome 10 at 93,045,278 bp
  • C to A, chromosome 10 at 112,182,486 bp
  • A to G, chromosome 10 at 127,048,478 bp
  • G to C, chromosome 11 at 70,017,225 bp
  • A to G, chromosome 11 at 85,173,284 bp
  • A to T, chromosome 11 at 107,074,476 bp
  • A to G, chromosome 11 at 116,148,220 bp
  • C to A, chromosome 12 at 4,939,689 bp
  • C to A, chromosome 12 at 71,947,098 bp
  • T to A, chromosome 14 at 12,091,192 bp
  • T to A, chromosome 14 at 50,425,031 bp
  • A to G, chromosome 14 at 60,378,551 bp
  • G to T, chromosome 15 at 8,148,383 bp
  • T to C, chromosome 15 at 10,633,164 bp
  • A to G, chromosome 16 at 4,311,588 bp
  • T to C, chromosome 16 at 20,193,645 bp
  • T to A, chromosome 17 at 23,357,024 bp
  • A to G, chromosome 17 at 23,460,378 bp
  • T to C, chromosome 17 at 24,678,725 bp
  • G to T, chromosome 17 at 24,720,978 bp
  • A to G, chromosome 19 at 4,142,714 bp
  • A to G, chromosome 19 at 10,200,291 bp
  • T to C, chromosome 19 at 12,241,496 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3161 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040612-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.