Strain Name:
C57BL/6J-MtgxR3712Btlr/Mmmh
Stock Number:
040705-MU
Citation ID:
RRID:MMRRC_040705-MU
Other Names:
R3712 (G1), C57BL/6J-MtgxR3712Btlr
Major Collection:

Gene Information

Pi4k2a
Name: phosphatidylinositol 4-kinase type 2 alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 84095
VEGA: 19
Homologene: 101681
Ncam2
Name: neural cell adhesion molecule 2
Synonyms: Ocam, RNCAM, R4B12 antigen, Ncam-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 17968
HGNC: HGNC:7657
Homologene: 3336
Orc1
Name: origin recognition complex, subunit 1
Synonyms: MmORC1, Orc1l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 18392
HGNC: HGNC:8487
Homologene: 31221
Rprd2
Name: regulation of nuclear pre-mRNA domain containing 2
Synonyms: 6720469I21Rik, 4930535B03Rik, 2810036A19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 75137
Homologene: 19997
Kmt2e
Name: lysine (K)-specific methyltransferase 2E
Synonyms: 1810033J14Rik, 9530077A04Rik, D230038D11Rik, Mll5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 69188
Homologene: 18822
Ccdc58
Name: coiled-coil domain containing 58
Synonyms: A930007B11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 381045
VEGA: 16
Homologene: 18028
Mta3
Name: metastasis associated 3
Synonyms: 1110002J22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 116871
Homologene: 14282
Dtnb
Name: dystrobrevin, beta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 13528
HGNC: HGNC:3058
Homologene: 74875
Mgll
Name: monoglyceride lipase
Synonyms: Magl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 23945
Homologene: 38298
Rbm27
Name: RNA binding motif protein 27
Synonyms: Psc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 225432
VEGA: 18
Homologene: 35410
Nedd4l
Name: neural precursor cell expressed, developmentally down-regulated gene 4-like
Synonyms: Nedd4b, Nedd4-2, 1300012C07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 83814
VEGA: 18
HGNC: HGNC:7728
Homologene: 86986
Pdcd11
Name: programmed cell death 11
Synonyms: ALG-4, 1110021I22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 18572
VEGA: 19
Homologene: 74968
Lars2
Name: leucyl-tRNA synthetase, mitochondrial
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 102436
VEGA: 9
Homologene: 6526
Clptm1l
Name: CLPTM1-like
Synonyms: C130052I12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 218335
VEGA: 13
Homologene: 12767
Ccnyl1
Name: cyclin Y-like 1
Synonyms: 9630037P07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 227210
Homologene: 65050
Dcaf13
Name: DDB1 and CUL4 associated factor 13
Synonyms: Wdsof1, LOC223499
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 223499
Homologene: 6430
Son
Name: Son DNA binding protein
Synonyms: 2900011L12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 20658
Homologene: 10551
Alx4
Name: aristaless-like homeobox 4
Synonyms: Aristaless-like 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 11695
HGNC: HGNC:450
Homologene: 7229
Dsp
Name: desmoplakin
Synonyms: 5730453H04Rik, DP, 2300002E22Rik, rul
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 109620
HGNC: HGNC:3052
Homologene: 37922
Sun2
Name: Sad1 and UNC84 domain containing 2
Synonyms: Unc84b, B230369L08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 223697
Homologene: 9113
Rrn3
Name: RRN3 RNA polymerase I transcription factor homolog (yeast)
Synonyms: TIF-1A, E130302O19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 106298
VEGA: 16
Homologene: 39531
Eps15
Name: epidermal growth factor receptor pathway substrate 15
Synonyms: 2410112D09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 13858
HGNC: HGNC:3419
Homologene: 128359
Klf5
Name: Kruppel-like factor 5
Synonyms: 4930520J07Rik, CKLF, Bteb2, IKLF
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 12224
VEGA: 14
HGNC: HGNC:6349
Homologene: 37520
Pcnx3
Name: pecanex homolog 3
Synonyms: Pcnxl3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 104401
Homologene: 17000
Mrnip
Name: MRN complex interacting protein
Synonyms: 3010026O09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 68067
Homologene: 75241
Ppp1r21
Name: protein phosphatase 1, regulatory subunit 21
Synonyms: Ccdc128, 1110018J12Rik, Klraq1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 73825
Homologene: 44811
Gnl2
Name: guanine nucleotide binding protein-like 2 (nucleolar)
Synonyms: Ngp-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230737
Homologene: 6858
Cep95
Name: centrosomal protein 95
Synonyms: Ccdc45, 4732496G21Rik, F630025I20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 320162
Homologene: 16297
Pigt
Name: phosphatidylinositol glycan anchor biosynthesis, class T
Synonyms: CGI-06, NDAP, Ndap7, 4930534E15Rik, 2510012P17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 78928
Homologene: 6134
Cep57l1
Name: centrosomal protein 57-like 1
Synonyms: 4930484D11Rik, 2410017P07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 103268
Homologene: 12254
Cep192
Name: centrosomal protein 192
Synonyms: 4631422C13Rik, D430014P18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 70799
VEGA: 18
Homologene: 73526
Hyal4
Name: hyaluronoglucosaminidase 4
Synonyms: 4632428M18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 77042
HGNC: HGNC:5323
Homologene: 69117
Pclo
Name: piccolo (presynaptic cytomatrix protein)
Synonyms: Acz, Pico
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 26875
Homologene: 69111
Kcnu1
Name: potassium channel, subfamily U, member 1
Synonyms: Slo3, Kcnma3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 16532
Homologene: 7392
Ush2a
Name: usherin
Synonyms: Ush2a, Ushrn, MUSH2A, A930037M10Rik, A930011D15Rik, LOC269160, LOC381317
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 22283
Homologene: 66151
Celsr2
Name: cadherin, EGF LAG seven-pass G-type receptor 2
Synonyms: Adgrc2, mfmi1, EGFL2, flamingo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 53883
HGNC: HGNC:3231
Homologene: 1078
Vmn1r59
Name: vomeronasal 1 receptor 59
Synonyms: V1rd10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 404284
HGNC: null
Homologene: 41799
Pard3b
Name: par-3 family cell polarity regulator beta
Synonyms: 1810008K04Rik, 2010002N16Rik, Als2cr19, 2810455B10Rik, PAR3beta, PAR3B, PAR3L
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 72823
Homologene: 35389
Fbxo44
Name: F-box protein 44
Synonyms: FBX30, FBG3, Fbxo6a, Fbx6a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230903
Homologene: 13232
Vmn2r111
Name: vomeronasal 2, receptor 111
Synonyms: EG210876
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 210876
HGNC: null
Homologene: 86604
Ubqlnl
Name: ubiquilin-like
Synonyms: 4922504M18Rik, LOC244179
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 244179
Homologene: 17034
Irf6
Name: interferon regulatory factor 6
Synonyms: E230028I05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 54139
HGNC: HGNC:6121
Homologene: 4479
Cldn10
Name: claudin 10
Synonyms: 6720456I16Rik, D14Ertd728e, Cldn10b, Cldn10a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 58187
HGNC: HGNC:2033
Homologene: 5076
Olfr121
Name: olfactory receptor 121
Synonyms: MOR263-4, GA_x6K02T2PSCP-2211113-2212078
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 258622
HGNC: null
Homologene: 17195
Trpv3
Name: transient receptor potential cation channel, subfamily V, member 3
Synonyms: VRL3, Nh, 1110036I10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 246788
Homologene: 17040
Cpeb2
Name: cytoplasmic polyadenylation element binding protein 2
Synonyms: A630055H10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231207
Homologene: 17995
Tectb
Name: tectorin beta
Synonyms: [b]-tectorin, Tctnb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 21684
Homologene: 7568
Arhgef26
Name: Rho guanine nucleotide exchange factor (GEF) 26
Synonyms: 8430436L14Rik, 4631416L12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 622434
Homologene: 9204
Akr1c20
Name: aldo-keto reductase family 1, member C20
Synonyms: 2610528B18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 116852
HGNC: null
Homologene: null
Arhgap31
Name: Rho GTPase activating protein 31
Synonyms: CdGAP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 12549
Homologene: 10644
Smtn
Name: smoothelin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 29856
Homologene: 8482
Sphkap
Name: SPHK1 interactor, AKAP domain containing
Synonyms: A930009L15Rik, SKIP, 4930544G21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 77629
Homologene: 18172
Lrfn2
Name: leucine rich repeat and fibronectin type III domain containing 2
Synonyms: SALM1, 5730420O05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 70530
Homologene: 19182
Zpld1
Name: zona pellucida like domain containing 1
Synonyms: 9430016A21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 239852
Homologene: 18401
Olfr411
Name: olfactory receptor 411
Synonyms: GA_x6K02T2P1NL-4481525-4480578, MOR255-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 258704
Homologene: 74999
Cyp2a4
Name: cytochrome P450, family 2, subfamily a, polypeptide 4
Synonyms: D7Ucla4, Cyp15a1, testosterone 15alpha-hydroxylase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 13086
Homologene: 85917
Olfr490
Name: olfactory receptor 490
Synonyms: MOR204-17, GA_x6K02T2PBJ9-10617173-10616229
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 258491
HGNC: null
Homologene: 73955
CAAA01123846.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
Ccdc162
Name: coiled-coil domain containing 162
Synonyms: Gm29096, Gm6976, 5033413D22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 75973
Homologene: 136355
Trdn
Name: triadin
Synonyms: EG432451, triadin-1, triadin 2, triadin 1, triadin 3, 2310045H21Rik, triadin-2, triadin-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 76757
VEGA: 10
Homologene: 38137
Bag2
Name: BCL2-associated athanogene 2
Synonyms: 2610042A13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 213539
HGNC: HGNC:938
Homologene: 31233
Apol7a
Name: apolipoprotein L 7a
Synonyms: Apol3, 9130022K13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 75761
HGNC: null
Homologene: 40940
Dipk1b
Name: divergent protein kinase domain 1B
Synonyms: Fam69b, PIP49, B230317C12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 56279
Homologene: 10516
Spopl
Name: speckle-type BTB/POZ protein-like
Synonyms: 4921517N04Rik, E430033K04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 76857
Homologene: 78016
Lpcat2
Name: lysophosphatidylcholine acyltransferase 2
Synonyms: Aytl1a, LPCAT2, Aytl1, lysoPAFAT/LPCAT2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 270084
Homologene: 41201
Olfr776
Name: olfactory receptor 776
Synonyms: MOR111-12, GA_x6K02T2PULF-10947193-10948131
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 404321
HGNC: null
Homologene: 115559
Sbspon
Name: somatomedin B and thrombospondin, type 1 domain containing
Synonyms: LOC226866, Gm106
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 226866
Homologene: 45950
2310079G19Rik
Name: RIKEN cDNA 2310079G19 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 69699
HGNC: null
Homologene: 137381
Fam53b
Name: family with sequence similarity 53, member B
Synonyms: A930008G19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 77938
Homologene: 8776
Srp14
Name: signal recognition particle 14
Synonyms: 14kDa, (homologous Alu RNA binding protein)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 20813
Homologene: 37738
Rpl7a-ps10
Name: ribosomal protein L7A, pseudogene 10
Synonyms: Gm6347
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 622727
HGNC: null
Homologene: null
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 15,892,445 bp
  • T to A, chromosome 1 at 33,746,916 bp
  • T to C, chromosome 1 at 62,343,978 bp
  • G to A, chromosome 1 at 64,714,668 bp
  • C to T, chromosome 1 at 83,277,112 bp
  • G to A, chromosome 1 at 188,810,292 bp
  • G to T, chromosome 1 at 193,162,623 bp
  • C to T, chromosome 2 at 23,537,380 bp
  • T to C, chromosome 2 at 26,632,638 bp
  • G to A, chromosome 2 at 93,642,789 bp
  • A to C, chromosome 2 at 118,478,959 bp
  • A to G, chromosome 2 at 164,501,645 bp
  • A to T, chromosome 3 at 62,423,629 bp
  • A to G, chromosome 3 at 95,764,560 bp
  • T to C, chromosome 3 at 108,400,839 bp
  • T to C, chromosome 4 at 108,604,021 bp
  • T to C, chromosome 4 at 109,309,177 bp
  • T to C, chromosome 4 at 125,046,274 bp
  • A to T, chromosome 4 at 148,156,004 bp
  • T to A, chromosome 4 at 156,350,124 bp
  • T to C, chromosome 5 at 14,723,224 bp
  • G to A, chromosome 5 at 23,495,971 bp
  • T to C, chromosome 5 at 43,278,592 bp
  • A to G, chromosome 6 at 24,756,514 bp
  • T to C, chromosome 6 at 88,764,588 bp
  • A to T, chromosome 7 at 5,454,638 bp
  • A to G, chromosome 7 at 26,307,827 bp
  • A to T, chromosome 7 at 104,149,138 bp
  • A to T, chromosome 7 at 108,286,456 bp
  • A to G, chromosome 7 at 132,759,925 bp
  • A to G, chromosome 8 at 25,881,420 bp
  • T to C, chromosome 8 at 92,918,170 bp
  • A to G, chromosome 9 at 97,179,873 bp
  • C to G, chromosome 9 at 123,453,403 bp
  • T to C, chromosome 10 at 33,157,166 bp
  • C to T, chromosome 10 at 41,587,379 bp
  • A to G, chromosome 10 at 41,743,114 bp
  • A to T, chromosome 10 at 129,261,224 bp
  • A to T, chromosome 11 at 3,532,865 bp
  • T to C, chromosome 11 at 50,182,590 bp
  • A to G, chromosome 11 at 73,278,954 bp
  • A to T, chromosome 11 at 74,347,197 bp
  • G to T, chromosome 11 at 106,811,286 bp
  • T to C, chromosome 12 at 3,648,213 bp
  • T to C, chromosome 13 at 4,510,223 bp
  • T to C, chromosome 13 at 38,151,802 bp
  • T to A, chromosome 13 at 73,616,038 bp
  • C to A, chromosome 14 at 99,299,228 bp
  • A to G, chromosome 14 at 118,855,110 bp
  • A to G, chromosome 15 at 39,145,267 bp
  • G to A, chromosome 15 at 77,393,545 bp
  • A to G, chromosome 15 at 79,727,913 bp
  • T to A, chromosome 16 at 13,784,095 bp
  • T to C, chromosome 16 at 36,081,405 bp
  • T to A, chromosome 16 at 38,602,533 bp
  • A to T, chromosome 16 at 55,226,436 bp
  • G to A, chromosome 16 at 81,465,544 bp
  • C to A, chromosome 16 at 88,627,523 bp
  • A to G, chromosome 16 at 91,656,726 bp
  • T to A, chromosome 17 at 22,568,830 bp
  • T to A, chromosome 17 at 37,752,380 bp
  • A to G, chromosome 17 at 49,071,160 bp
  • A to G, chromosome 17 at 83,762,988 bp
  • G to T, chromosome 17 at 88,549,479 bp
  • T to C, chromosome 18 at 42,292,112 bp
  • G to A, chromosome 18 at 65,209,719 bp
  • C to A, chromosome 18 at 67,820,329 bp
  • G to A, chromosome 19 at 5,683,339 bp
  • C to G, chromosome 19 at 5,683,340 bp
  • G to A, chromosome 19 at 42,090,692 bp
  • T to A, chromosome 19 at 47,127,245 bp
  • C to G, chromosome 19 at 55,180,999 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3712 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040705-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.