Strain Name:
C57BL/6J-MtgxR3742Btlr/Mmmh
Stock Number:
040728-MU
Citation ID:
RRID:MMRRC_040728-MU
Other Names:
R3742 (G1), C57BL/6J-MtgxR3742Btlr
Major Collection:

Gene Information

Mtss1
Name: MTSS I-BAR domain containing 1
Synonyms: MIM, D130001D01Rik, 2310003N14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 211401
VEGA: 15
Homologene: 8841
Nup210l
Name: nucleoporin 210-like
Synonyms: 4930548O11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 77595
Homologene: 28122
Bclaf3
Name: Bclaf1 and Thrap3 family member 3
Synonyms: LOC382252, A830080D01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 382252
Homologene: 28098
Epb41l5
Name: erythrocyte membrane protein band 4.1 like 5
Synonyms: NBL5, 1700030C16Rik, E230025E14Rik, Lulu1, Epb4.1l5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226352
Homologene: 32492
Nsf
Name: N-ethylmaleimide sensitive fusion protein
Synonyms: SKD2, N-ethylmaleimide sensitive factor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 18195
HGNC: HGNC:8016
Homologene: 4502
Pop1
Name: processing of precursor 1, ribonuclease P/MRP family, (S. cerevisiae)
Synonyms: 4932434G09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 67724
Homologene: 41000
Dab1
Name: disabled 1
Synonyms: C630028C02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 13131
HGNC: HGNC:2661
Homologene: 32084
Frem1
Name: Fras1 related extracellular matrix protein 1
Synonyms: eyem02Jus, heb, QBRICK, eyes2, crf11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 329872
Homologene: 27049
Dsg4
Name: desmoglein 4
Synonyms: lah, CDHF13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 16769
Homologene: 65341
Zfp335
Name: zinc finger protein 335
Synonyms: 1810045J01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 329559
Homologene: 11129
Nol11
Name: nucleolar protein 11
Synonyms: 1500002M01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 68979
Homologene: 32264
Ing5
Name: inhibitor of growth family, member 5
Synonyms: 1810018M11Rik, 1700027H23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 66262
Homologene: 90955
Zfp386
Name: zinc finger protein 386 (Kruppel-like)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 56220
Homologene: 51668
Pde4d
Name: phosphodiesterase 4D, cAMP specific
Synonyms: dunce, Dpde3, 9630011N22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 238871
HGNC: HGNC:8783
Dnah11
Name: dynein, axonemal, heavy chain 11
Synonyms: lrd, b2b1279Clo, b2b1203Clo, b2b598Clo, b2b1289Clo, b2b1727Clo, Dnahc11, avc4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 13411
HGNC: HGNC:2942
Homologene: 2801
Pde5a
Name: phosphodiesterase 5A, cGMP-specific
Synonyms: PDE5A1, Pde5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 242202
HGNC: HGNC:8784
Homologene: 842
Zfp605
Name: zinc finger protein 605
Synonyms: A830023I12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 675812
Homologene: 52335
B4galt3
Name: UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 3
Synonyms: beta4GalT-III, ESTM26, 9530061M23Rik, R74981
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 57370
HGNC: HGNC:926
Homologene: 48241
Mroh2a
Name: maestro heat-like repeat family member 2A
Synonyms: ENSMUSG00000044873, OTTMUSG00000020804, Heatr7b1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 100040766
Homologene: 85300
Mbd6
Name: methyl-CpG binding domain protein 6
Synonyms: D10Wsu93e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 110962
Homologene: 14171
Bsn
Name: bassoon
Synonyms: presynaptic cytomatrix protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12217
HGNC: HGNC:1117
Homologene: 31161
Hinfp
Name: histone H4 transcription factor
Synonyms: DKFZp434F162, Mizf
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 102423
VEGA: 9
Homologene: 9174
Olfr859
Name: olfactory receptor 859
Synonyms: GA_x6K02T2PVTD-13548326-13549255, MOR146-3, MOR146-10_p
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258519
Homologene: 134093
Shisa9
Name: shisa family member 9
Synonyms: 2700045P11Rik, CKAMP44
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 72555
Homologene: 109462
Tiam2
Name: T cell lymphoma invasion and metastasis 2
Synonyms: STEF, 3000002F19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 24001
VEGA: 17
Homologene: 40796
Ctso
Name: cathepsin O
Synonyms: A330105D01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229445
HGNC: HGNC:2542
Homologene: 1020
Cdh18
Name: cadherin 18
Synonyms: B230220E17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 320865
HGNC: HGNC:1757
Homologene: 55858
Dip2a
Name: disco interacting protein 2 homolog A
Synonyms: Kiaa0184-hp, 4931420H10Rik, Dip2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 64451
Homologene: 41012
Olfr1113
Name: olfactory receptor 1113
Synonyms: GA_x6K02T2Q125-48697747-48698727, MOR264-25
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 404327
Homologene: 27114
Olfr843
Name: olfactory receptor 843
Synonyms: GA_x6K02T2PVTD-12986331-12985390, MOR155-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258560
Homologene: 74251
Atp8b2
Name: ATPase, class I, type 8B, member 2
Synonyms: Id
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 54667
Homologene: 23226
Fbxo6
Name: F-box protein 6
Synonyms: Fbx6b, FBG2, Fbs2, Fbxo6b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 50762
Homologene: 9274
Tmem88b
Name: transmembrane protein 88B
Synonyms: A230069A22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 320587
Homologene: 85849
Olfr1459
Name: olfactory receptor 1459
Synonyms: GA_x6K02T2RE5P-3473421-3472498, MOR202-17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 258684
Homologene: 115532
Gtpbp2
Name: GTP binding protein 2
Synonyms: nmf205
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 56055
HGNC: HGNC:4670
Homologene: 10420
Hemgn
Name: hemogen
Synonyms: EDAG, 4921524M03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 93966
Homologene: 14223
Hoxc13
Name: homeobox C13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 15422
HGNC: HGNC:5125
Homologene: 7770
Syngr4
Name: synaptogyrin 4
Synonyms: 1700016O14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 58867
Homologene: 8258
AC121888.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 31,287,683 bp
  • CTCTCTCTCTCTCTCTCTCTC to CTCTCTCTCTCTCTCTCTCTCTCTCTCTC, chromosome 1 at 88,247,720 bp
  • T to A, chromosome 1 at 93,812,676 bp
  • T to C, chromosome 1 at 119,605,243 bp
  • C to A, chromosome 1 at 171,274,043 bp
  • A to G, chromosome 2 at 87,212,996 bp
  • G to A, chromosome 2 at 164,907,414 bp
  • G to A, chromosome 3 at 81,952,249 bp
  • C to G, chromosome 3 at 89,946,031 bp
  • A to T, chromosome 3 at 90,207,394 bp
  • T to C, chromosome 3 at 122,835,650 bp
  • T to C, chromosome 4 at 46,396,421 bp
  • A to C, chromosome 4 at 83,011,867 bp
  • C to T, chromosome 4 at 104,731,751 bp
  • A to G, chromosome 4 at 148,149,633 bp
  • A to G, chromosome 4 at 155,785,427 bp
  • G to T, chromosome 5 at 110,128,698 bp
  • T to C, chromosome 7 at 45,895,770 bp
  • A to G, chromosome 9 at 19,248,683 bp
  • A to T, chromosome 9 at 19,808,899 bp
  • A to G, chromosome 9 at 44,302,515 bp
  • C to A, chromosome 9 at 108,105,739 bp
  • A to T, chromosome 10 at 76,276,714 bp
  • G to A, chromosome 10 at 127,284,943 bp
  • C to T, chromosome 11 at 103,930,752 bp
  • G to A, chromosome 11 at 107,180,031 bp
  • T to A, chromosome 12 at 116,059,550 bp
  • A to G, chromosome 12 at 118,131,341 bp
  • T to G, chromosome 13 at 109,740,479 bp
  • T to A, chromosome 15 at 23,226,991 bp
  • T to C, chromosome 15 at 34,528,868 bp
  • C to T, chromosome 15 at 58,947,534 bp
  • G to A, chromosome 15 at 102,921,438 bp
  • G to A, chromosome 16 at 12,267,664 bp
  • A to G, chromosome 17 at 3,414,113 bp
  • A to G, chromosome 17 at 46,165,882 bp
  • A to T, chromosome 18 at 20,471,001 bp
  • A to G, chromosome 19 at 13,145,894 bp
  • T to A, chromosome X at 159,551,832 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3742 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040728-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.