Strain Name:
C57BL/6J-MtgxR3797Btlr/Mmmh
Stock Number:
040758-MU
Citation ID:
RRID:MMRRC_040758-MU
Other Names:
R3797 (G1), C57BL/6J-MtgxR3797Btlr
Major Collection:

Gene Information

Itgb8
Name: integrin beta 8
Synonyms: 4832412O06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 320910
HGNC: HGNC:6163
Homologene: 18567
Limch1
Name: LIM and calponin homology domains 1
Synonyms: 3732412D22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 77569
Homologene: 18953
Lmf1
Name: lipase maturation factor 1
Synonyms: Tmem112, 2400010G15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 76483
Homologene: 23384
Mtarc2
Name: mitochondrial amidoxime reducing component 2
Synonyms: Marc2, Mosc2, 2810484M10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 67247
Homologene: 9904
Zfp934
Name: zinc finger protein 934
Synonyms: 6720457D02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 77117
VEGA: 13
Xpnpep1
Name: X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
Synonyms: D230045I08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 170750
Homologene: 6424
B4galt1
Name: UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
Synonyms: Ggtb2, GalT, Ggtb, B-1,4-GalT1, beta-1,4-GalT1, beta 1,4-Galactosyltransferase I, b1,4-Galactosyltransferase I
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 14595
HGNC: HGNC:924
Homologene: 20378
Fgfr1
Name: fibroblast growth factor receptor 1
Synonyms: Hspy, FGFR-I, Flt-2, Eask, Fr1, Fgfr-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 14182
HGNC: HGNC:3688
Homologene: 69065
Polk
Name: polymerase (DNA directed), kappa
Synonyms: Dinb1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 27015
VEGA: 13
HGNC: HGNC:9183
Homologene: 32140
Setd2
Name: SET domain containing 2
Synonyms: KMT3A, 4921524K10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235626
Homologene: 56493
Rab11fip3
Name: RAB11 family interacting protein 3 (class II)
Synonyms: Rab11-FIP3, D030060O14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 215445
Homologene: 49396
Cdc73
Name: cell division cycle 73, Paf1/RNA polymerase II complex component
Synonyms: 8430414L16Rik, Hrpt2, C130030P16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 214498
Homologene: 11571
Xdh
Name: xanthine dehydrogenase
Synonyms: xanthine oxidase, Xox1, Xox-1, Xor, XO
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 22436
VEGA: 17
Homologene: 324
Basp1
Name: brain abundant, membrane attached signal protein 1
Synonyms: Ckap3, CAP-23, 2610024P12Rik, CAP23
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 70350
VEGA: 15
HGNC: HGNC:957
Homologene: 38168
Dsp
Name: desmoplakin
Synonyms: 2300002E22Rik, rul, 5730453H04Rik, DP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 109620
HGNC: HGNC:3052
Homologene: 37922
Pacs1
Name: phosphofurin acidic cluster sorting protein 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 107975
VEGA: 19
Homologene: 9970
Phrf1
Name: PHD and ring finger domains 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 101471
Homologene: 16377
Eif3d
Name: eukaryotic translation initiation factor 3, subunit D
Synonyms: Eif3s7, eIF3p66, 66/67kDa, mouse translation initiation factor eIF3 p66
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 55944
VEGA: 15
HGNC: HGNC:3278
Homologene: 2782
Clec14a
Name: C-type lectin domain family 14, member a
Synonyms: 1200003C23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 66864
VEGA: 12
Homologene: 12047
Adgrf3
Name: adhesion G protein-coupled receptor F3
Synonyms: Gpr113, LOC381628, PGR23
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 381628
Homologene: 17826
Cops7a
Name: COP9 signalosome subunit 7A
Synonyms: D6Ertd35e, COP9 complex S7a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 26894
Homologene: 22685
Svil
Name: supervillin
Synonyms: B430302E16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 225115
Homologene: 25090
Vps13a
Name: vacuolar protein sorting 13A
Synonyms: D330038K10Rik, 4930543C13Rik, 4930516E05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 271564
VEGA: 19
HGNC: HGNC:1908
Homologene: 22068
Ltbp1
Name: latent transforming growth factor beta binding protein 1
Synonyms: 9430031G15Rik, Ltbp1L, LTBP-1, b2b1000Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 268977
HGNC: HGNC:6714
Homologene: 522
Wdfy4
Name: WD repeat and FYVE domain containing 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 545030
Homologene: 83473
Pak5
Name: p21 (RAC1) activated kinase 5
Synonyms: Pak5, Pak7, 2900083L08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241656
Homologene: 22211
Vmn2r72
Name: vomeronasal 2, receptor 72
Synonyms: EG244114, Vmn2r72-ps
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 244114
Homologene: 115466
Alpk3
Name: alpha-kinase 3
Synonyms: Midori
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 116904
Homologene: 10813
Ephb1
Name: Eph receptor B1
Synonyms: Net, C130099E04Rik, Hek6, Cek6, Elk, Elkh
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 270190
HGNC: HGNC:3392
Homologene: 20936
Ugt3a1
Name: UDP glycosyltransferases 3 family, polypeptide A1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 105887
Homologene: 122787
Ccdc170
Name: coiled-coil domain containing 170
Synonyms: Gm221, LOC237250
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 100504234
Homologene: 69393
Capn5
Name: calpain 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 12337
HGNC: HGNC:1482
Homologene: 31212
Clns1a
Name: chloride channel, nucleotide-sensitive, 1A
Synonyms: Clcni, 2610100O04Rik, ICLN, 2610036D06Rik, Clci
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 12729
HGNC: HGNC:2080
Homologene: 990
Skida1
Name: SKI/DACH domain containing 1
Synonyms: 2810030E01Rik, 5730507N06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 72668
Homologene: 66327
Gm2128
Name: predicted gene 2128
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 100039269
Homologene: 45597
Olfr620
Name: olfactory receptor 620
Synonyms: GA_x6K02T2PBJ9-6335095-6334154, MOR4-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258808
Homologene: 103777
H2-Q7
Name: histocompatibility 2, Q region locus 7
Synonyms: H-2Q7, Ped, Qa7, Qa-7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 15018
HGNC: HGNC:4931
Homologene: 128352
Ppl
Name: periplakin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 19041
VEGA: 16
HGNC: HGNC:9273
Homologene: 2026
Slc35g3
Name: solute carrier family 35, member G3
Synonyms: Amac1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 56293
Homologene: 89413
Fam43b
Name: family with sequence similarity 43, member B
Synonyms: OTTMUSG00000009974
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 625638
Homologene: 45810
Gm16170
Name: predicted gene 16170
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 143,677,723 bp
  • T to C, chromosome 1 at 184,841,308 bp
  • C to A, chromosome 2 at 18,045,897 bp
  • T to C, chromosome 2 at 136,100,826 bp
  • G to A, chromosome 4 at 40,807,258 bp
  • G to C, chromosome 4 at 138,395,098 bp
  • T to C, chromosome 5 at 30,196,823 bp
  • A to G, chromosome 5 at 66,969,079 bp
  • C to T, chromosome 6 at 124,959,832 bp
  • G to A, chromosome 7 at 41,157,835 bp
  • C to A, chromosome 7 at 81,092,753 bp
  • T to C, chromosome 7 at 85,738,077 bp
  • G to A, chromosome 7 at 97,696,835 bp
  • C to T, chromosome 7 at 98,125,829 bp
  • C to T, chromosome 7 at 103,611,447 bp
  • C to T, chromosome 7 at 141,259,918 bp
  • G to A, chromosome 8 at 25,572,437 bp
  • T to C, chromosome 9 at 101,971,267 bp
  • T to C, chromosome 9 at 110,549,571 bp
  • G to A, chromosome 10 at 4,560,920 bp
  • A to G, chromosome 11 at 48,845,670 bp
  • A to G, chromosome 11 at 69,760,917 bp
  • G to A, chromosome 12 at 58,267,909 bp
  • T to C, chromosome 12 at 119,163,469 bp
  • T to A, chromosome 13 at 38,177,284 bp
  • T to C, chromosome 13 at 62,517,888 bp
  • A to T, chromosome 13 at 96,486,982 bp
  • A to T, chromosome 14 at 33,140,645 bp
  • G to A, chromosome 15 at 9,310,641 bp
  • C to A, chromosome 15 at 25,364,312 bp
  • A to G, chromosome 15 at 77,968,569 bp
  • T to C, chromosome 16 at 5,104,550 bp
  • G to A, chromosome 17 at 25,654,471 bp
  • A to G, chromosome 17 at 26,068,526 bp
  • C to T, chromosome 17 at 35,439,438 bp
  • T to C, chromosome 17 at 73,907,658 bp
  • A to G, chromosome 17 at 75,362,630 bp
  • T to A, chromosome 18 at 5,060,534 bp
  • T to C, chromosome 19 at 5,167,912 bp
  • T to C, chromosome 19 at 16,745,947 bp
  • A to T, chromosome 19 at 53,006,342 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3797 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040758-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.