Strain Name:
C57BL/6J-MtgxR3870Btlr/Mmmh
Stock Number:
040789-MU
Citation ID:
RRID:MMRRC_040789-MU
Other Names:
R3870 (G1), C57BL/6J-MtgxR3870Btlr
Major Collection:

Gene Information

Atg7
Name: autophagy related 7
Synonyms: 1810013K23Rik, Apg7l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 74244
Homologene: 4662
Scg3
Name: secretogranin III
Synonyms: 1B1075, Chgd, SgIII
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 20255
VEGA: 9
Homologene: 7526
Vps13c
Name: vacuolar protein sorting 13C
Synonyms: C230055H22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 320528
VEGA: 9
Homologene: 41188
Prex2
Name: phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
Synonyms: Depdc2, 6230420N16Rik, C030045D06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 109294
Homologene: 23523
Pard3
Name: par-3 family cell polarity regulator
Synonyms: Pard3a, PAR-3, Par3, ASIP, D8Ertd580e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 93742
Homologene: 10489
Eif4g3
Name: eukaryotic translation initiation factor 4 gamma, 3
Synonyms: eIF4GII, G1-419-52, repro8, 4930523M17Rik, 1500002J22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230861
HGNC: HGNC:3298
Homologene: 2789
Usp14
Name: ubiquitin specific peptidase 14
Synonyms: nmf375, ax, ataxia, 2610037B11Rik, 2610005K12Rik, dUB-type TGT, NMF375
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 59025
Homologene: 3780
Usp32
Name: ubiquitin specific peptidase 32
Synonyms: 2900074J03Rik, 6430526O11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 237898
Homologene: 13066
Xrcc6
Name: X-ray repair complementing defective repair in Chinese hamster cells 6
Synonyms: G22p1, Ku p70, Ku70
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 14375
HGNC: HGNC:4055
Homologene: 37483
Exoc5
Name: exocyst complex component 5
Synonyms: SEC10, Sec10l1, PRO1912
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 105504
Homologene: 38195
Ccdc93
Name: coiled-coil domain containing 93
Synonyms: 4633402D15Rik, 9230102M16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 70829
Homologene: 10393
Lmtk2
Name: lemur tyrosine kinase 2
Synonyms: 2900041G10Rik, AATYK2, KPI-2, cprk, KPI2, A330101P12Rik, BREK
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231876
Homologene: 8948
Kctd9
Name: potassium channel tetramerisation domain containing 9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 105440
Homologene: 9754
Ehd4
Name: EH-domain containing 4
Synonyms: 2210022F10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 98878
HGNC: HGNC:3245
Homologene: 26430
Cc2d2a
Name: coiled-coil and C2 domain containing 2A
Synonyms: b2b1035Clo, 5730509K17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231214
Homologene: 18159
Gpatch2
Name: G patch domain containing 2
Synonyms: Gpatc2, 5830436K05Rik, 5830433G22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 67769
Homologene: 9976
Satb2
Name: special AT-rich sequence binding protein 2
Synonyms: BAP002
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 212712
Homologene: 32249
Tnfrsf10b
Name: tumor necrosis factor receptor superfamily, member 10b
Synonyms: TRAILR2, TRICK2A, Trail Receptor, Ly98, Killer/Dr5, DR5, TRICK2B, KILLER, TRICKB, TRAIL-R2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 21933
VEGA: 14
Homologene: 129806
Glud1
Name: glutamate dehydrogenase 1
Synonyms: Gdh-X, Glud
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 14661
HGNC: HGNC:4335
Homologene: 55885
Lingo1
Name: leucine rich repeat and Ig domain containing 1
Synonyms: LERN1, LINGO-1, 4930471K13Rik, Lrrn6a, UNQ201
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235402
Homologene: 41891
Pfkl
Name: phosphofructokinase, liver, B-type
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 18641
HGNC: HGNC:8876
Homologene: 55668
Akap8
Name: A kinase (PRKA) anchor protein 8
Synonyms: AKAP95, 1200016A02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 56399
VEGA: 17
HGNC: HGNC:378
Homologene: 4278
Dbr1
Name: debranching RNA lariats 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 83703
Homologene: 9428
Map1s
Name: microtubule-associated protein 1S
Synonyms: Bpy2ip1, 6430517J16Rik, Mtap1s, Map8, VCY2IP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 270058
Homologene: 10047
Dhx37
Name: DEAH (Asp-Glu-Ala-His) box polypeptide 37
Synonyms: LOC208144, LOC381671
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 208144
Homologene: 6641
Slc35f5
Name: solute carrier family 35, member F5
Synonyms: 1300003P13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 74150
Homologene: 5745
Uncx
Name: UNC homeobox
Synonyms: Uncx4.1, Chx4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 22255
Homologene: 56598
Tas1r3
Name: taste receptor, type 1, member 3
Synonyms: T1r3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 83771
Homologene: 12890
Ldb3
Name: LIM domain binding 3
Synonyms: cypher, ZASP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 24131
VEGA: 14
Homologene: 134626
Stxbp2
Name: syntaxin binding protein 2
Synonyms: Sxtp2, muSec1, Munc18b, Munc-18b, C79054, Munc-18-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 20911
Homologene: 55530
Myo16
Name: myosin XVI
Synonyms: BM140241, C230040D10Rik, Nyap3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 244281
Homologene: 34710
Magi2
Name: membrane associated guanylate kinase, WW and PDZ domain containing 2
Synonyms: S-SCAM, Acvrinp1, Magi-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 50791
Homologene: 8189
Vmn2r6
Name: vomeronasal 2, receptor 6
Synonyms: EG620718, EG667069
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 667069
Homologene: 129754
Ncoa6
Name: nuclear receptor coactivator 6
Synonyms: AIB3, RAP250, PRIP, NRC, ASC2, ASC-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 56406
Homologene: 137337
Tppp
Name: tubulin polymerization promoting protein
Synonyms: 2900041A09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 72948
Homologene: 21389
Cplane1
Name: ciliogenesis and planar polarity effector 1
Synonyms: Hug, Jbts17, b2b012Clo, 2410089E03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 73692
Homologene: 11315
Rubcnl
Name: RUN and cysteine rich domain containing beclin 1 interacting protein like
Synonyms: 5031414D18Rik, LOC380917
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 271221
VEGA: 14
Homologene: 57021
Plcb1
Name: phospholipase C, beta 1
Synonyms: 3110043I21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 18795
Homologene: 22876
Gm10985
Name: predicted gene 10985
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
Zscan20
Name: zinc finger and SCAN domains 20
Synonyms: Zfp31
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 269585
Homologene: 51463
Vmn2r77
Name: vomeronasal 2, receptor 77
Synonyms: EG546983
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 546983
Homologene: 115466
Rasal3
Name: RAS protein activator like 3
Synonyms: A430107D22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 320484
Homologene: 18901
Stat2
Name: signal transducer and activator of transcription 2
Synonyms: 1600010G07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 20847
VEGA: 10
Homologene: 3952
Vstm4
Name: V-set and transmembrane domain containing 4
Synonyms: E130203B14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 320736
Homologene: 18707
Ces1d
Name: carboxylesterase 1D
Synonyms: Ces3, TGH
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 104158
HGNC: HGNC:1863
Homologene: 35606
Trim12c
Name: tripartite motif-containing 12C
Synonyms: Trim12-2, 9230105E10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 319236
Homologene: 75345
Adam22
Name: a disintegrin and metallopeptidase domain 22
Synonyms: 2900022I03Rik, MDC2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 11496
HGNC: HGNC:201
Homologene: 37898
4832428D23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
Atxn7l3b
Name: ataxin 7-like 3B
Synonyms: ENSMUSG00000074747, 4921506J03Rik, 6230409E21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 382423
Homologene: 115930
Snx33
Name: sorting nexin 33
Synonyms: Sh3px3, E130307J07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235406
VEGA: 9
Homologene: 45165
Pgbd1
Name: piggyBac transposable element derived 1
Synonyms: 4921509E05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 319207
Homologene: 130030
Mast1
Name: microtubule associated serine/threonine kinase 1
Synonyms: SAST, SAST170, 9430008B02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 56527
Homologene: 10543
Olfr701
Name: olfactory receptor 701
Synonyms: 4932441H21Rik, GA_x6K02T2PBJ9-9195805-9196755, MOR283-1, 4933433E02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 66786
Homologene: 12558
Ttbk2
Name: tau tubulin kinase 2
Synonyms: 2610507N02Rik, B930008N24Rik, TTK
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 140810
Homologene: 62795
Cntnap5a
Name: contactin associated protein-like 5A
Synonyms: Caspr5-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 636808
Homologene: 43974
Hrh1
Name: histamine receptor H1
Synonyms: Bphs, Hir
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 15465
HGNC: HGNC:5182
Homologene: 668
Mfsd4a
Name: major facilitator superfamily domain containing 4A
Synonyms: A930031D07Rik, Mfsd4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 213006
Homologene: 45419
Togaram1
Name: TOG array regulator of axonemal microtubules 1
Synonyms: A430041B07Rik, Fam179b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 328108
VEGA: 12
Homologene: 15025
Gm11555
Name: predicted gene 11555
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 546511
Ryk
Name: receptor-like tyrosine kinase
Synonyms: Vik, ERK-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 20187
Homologene: 68287
Armcx2
Name: armadillo repeat containing, X-linked 2
Synonyms: 3230401N03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
Alteration at locus: Chemically Induced
NCBI: 67416
Homologene: 12125
Gcm1
Name: glial cells missing homolog 1
Synonyms: glide, GCMa, Gcm1-rs1, glial cell deficient, Gcm 1, Gcm a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 14531
VEGA: 9
HGNC: HGNC:4197
Homologene: 2702
Tlr12
Name: toll-like receptor 12
Synonyms: LOC384059, Tlr11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 384059
Homologene: 135964
Sall2
Name: spalt like transcription factor 2
Synonyms: Msal-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 50524
Homologene: 9269
Mmel1
Name: membrane metallo-endopeptidase-like 1
Synonyms: NEPLP gamma, NEPLP beta, Mell1, Nep2, NEPLP alpha, SEP, Nl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 27390
Homologene: 22778
Nipa2
Name: non imprinted in Prader-Willi/Angelman syndrome 2 homolog (human)
Synonyms: 3830408P04Rik, 2600017P10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 93790
Homologene: 11368
Oaf
Name: out at first homolog
Synonyms: D130038B21Rik, D9Ucla1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 102644
VEGA: 9
Homologene: 14334
1700028J19Rik
Name: RIKEN cDNA 1700028J19 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 70004
Crygs
Name: crystallin, gamma S
Synonyms: Opj
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 12970
VEGA: 16
HGNC: HGNC:2417
Homologene: 40695
Hnrnpa0
Name: heterogeneous nuclear ribonucleoprotein A0
Synonyms: 1110055B05Rik, 3010025E17Rik, Hnrpa0
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 77134
VEGA: 13
HGNC: HGNC:5030
Homologene: 136809
Gm5468
Name: predicted gene 5468
Synonyms: 100040583
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 432939
VEGA: 15
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 11,160,192 bp
  • G to A, chromosome 1 at 44,206,364 bp
  • A to G, chromosome 1 at 56,891,220 bp
  • A to G, chromosome 1 at 116,060,249 bp
  • A to G, chromosome 1 at 121,463,114 bp
  • A to G, chromosome 1 at 125,562,361 bp
  • G to A, chromosome 1 at 132,046,353 bp
  • T to A, chromosome 1 at 187,322,294 bp
  • T to A, chromosome 2 at 120,136,953 bp
  • T to G, chromosome 2 at 120,740,019 bp
  • A to C, chromosome 2 at 135,325,671 bp
  • T to C, chromosome 2 at 155,415,557 bp
  • TTCTCTCTCTCTCTCTCT to TTCTCTCTCTCTCTCT, chromosome 3 at 53,845,205 bp
  • T to C, chromosome 3 at 64,556,621 bp
  • A to G, chromosome 4 at 128,586,425 bp
  • T to A, chromosome 4 at 128,616,568 bp
  • T to A, chromosome 4 at 138,096,900 bp
  • T to C, chromosome 4 at 154,883,638 bp
  • A to T, chromosome 4 at 155,861,353 bp
  • C to A, chromosome 5 at 8,132,418 bp
  • T to C, chromosome 5 at 20,609,251 bp
  • C to A, chromosome 5 at 43,718,691 bp
  • G to A, chromosome 5 at 125,418,648 bp
  • T to C, chromosome 5 at 139,547,365 bp
  • T to G, chromosome 5 at 144,166,427 bp
  • A to G, chromosome 6 at 114,480,919 bp
  • T to C, chromosome 6 at 114,697,047 bp
  • T to A, chromosome 7 at 44,231,404 bp
  • T to C, chromosome 7 at 55,932,942 bp
  • T to C, chromosome 7 at 86,811,842 bp
  • T to C, chromosome 7 at 104,348,337 bp
  • T to A, chromosome 7 at 106,818,840 bp
  • A to G, chromosome 8 at 3,634,079 bp
  • A to T, chromosome 8 at 10,442,239 bp
  • A to G, chromosome 8 at 70,917,101 bp
  • G to A, chromosome 8 at 84,918,731 bp
  • C to G, chromosome 8 at 93,175,086 bp
  • T to C, chromosome 8 at 127,409,686 bp
  • C to T, chromosome 9 at 43,222,758 bp
  • A to T, chromosome 9 at 56,619,725 bp
  • T to C, chromosome 9 at 56,926,740 bp
  • A to G, chromosome 9 at 67,884,726 bp
  • T to C, chromosome 9 at 75,675,499 bp
  • T to A, chromosome 9 at 78,059,841 bp
  • A to T, chromosome 9 at 99,576,561 bp
  • A to G, chromosome 9 at 102,891,228 bp
  • A to G, chromosome 10 at 78,001,509 bp
  • A to G, chromosome 10 at 112,928,828 bp
  • T to A, chromosome 10 at 128,277,893 bp
  • A to T, chromosome 11 at 85,007,055 bp
  • G to T, chromosome 11 at 99,649,990 bp
  • A to C, chromosome 12 at 65,002,645 bp
  • C to T, chromosome 13 at 21,434,370 bp
  • G to A, chromosome 13 at 58,127,899 bp
  • A to G, chromosome 13 at 74,030,772 bp
  • C to T, chromosome 14 at 32,863,755 bp
  • T to A, chromosome 14 at 34,325,580 bp
  • A to T, chromosome 14 at 34,567,483 bp
  • A to G, chromosome 14 at 49,019,396 bp
  • C to A, chromosome 14 at 52,313,994 bp
  • T to C, chromosome 14 at 67,733,152 bp
  • T to G, chromosome 14 at 69,773,456 bp
  • C to T, chromosome 14 at 75,040,916 bp
  • A to T, chromosome 15 at 8,218,464 bp
  • A to G, chromosome 15 at 25,414,475 bp
  • T to A, chromosome 15 at 82,025,684 bp
  • C to T, chromosome 16 at 22,805,551 bp
  • G to A, chromosome 17 at 32,317,839 bp
  • G to A, chromosome 17 at 32,393,548 bp
  • A to G, chromosome 18 at 10,002,370 bp
  • A to T, chromosome X at 134,806,299 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3870 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040789-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.