Strain Name:
C57BL/6J-MtgxR3896Btlr/Mmmh
Stock Number:
040807-MU
Citation ID:
RRID:MMRRC_040807-MU
Other Names:
R3896 (G1), C57BL/6J-MtgxR3896Btlr
Major Collection:

Gene Information

Gsn
Name: gelsolin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227753
HGNC: HGNC:4620
Homologene: 147
Macf1
Name: microtubule-actin crosslinking factor 1
Synonyms: trabeculin alpha, Acf7, Aclp7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 11426
Homologene: 136191
Emb
Name: embigin
Synonyms: Gp70
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 13723
Homologene: 7743
Foxp1
Name: forkhead box P1
Synonyms: 4932443N09Rik, 3110052D19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 108655
HGNC: HGNC:3823
Homologene: 13092
Ywhah
Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
Synonyms: 14-3-3 eta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 22629
Homologene: 37767
Scn8a
Name: sodium channel, voltage-gated, type VIII, alpha
Synonyms: NMF335, Nav1.6, mnd-2, NaCh6, motor end-plate disease, nmf2, seal, ataxia 3, mnd2, nur14, nmf58, C630029C19Rik, med, nmf335
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 20273
Homologene: 7927
Ints1
Name: integrator complex subunit 1
Synonyms: 1110015K06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 68510
Homologene: 53111
Taf4
Name: TATA-box binding protein associated factor 4
Synonyms: Taf4a, TAFII135, Taf2c1, TAFII130
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228980
Homologene: 55723
Myo1b
Name: myosin IB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 17912
HGNC: HGNC:7596
Homologene: 7856
Cog7
Name: component of oligomeric golgi complex 7
Synonyms: 5630400E24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233824
Homologene: 33431
Gdf10
Name: growth differentiation factor 10
Synonyms: Bmp3b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 14560
VEGA: 14
HGNC: HGNC:4215
Homologene: 3640
Rnf123
Name: ring finger protein 123
Synonyms: KPC1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 84585
Homologene: 11112
Ccdc80
Name: coiled-coil domain containing 80
Synonyms: DRO1, Ssg1, 2610001E17Rik, Urb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 67896
Homologene: 12206
Sgo2a
Name: shugoshin 2A
Synonyms: 5730576N04Rik, D1Ertd8e, Sgol2a, 1110007N04Rik, Sgol2, Tripin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 68549
Homologene: 51867
Slc25a46
Name: solute carrier family 25, member 46
Synonyms: 1200007B05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 67453
VEGA: 18
Homologene: 14518
Sox14
Name: SRY (sex determining region Y)-box 14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 20669
Homologene: 31224
Enpp3
Name: ectonucleotide pyrophosphatase/phosphodiesterase 3
Synonyms: CD203c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 209558
VEGA: 10
HGNC: HGNC:3358
Homologene: 3683
Klhl28
Name: kelch-like 28
Synonyms: 4122402F11Rik, 4931401E10Rik, Btbd5, 2810440N09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 66689
VEGA: 12
Homologene: 23036
Reg4
Name: regenerating islet-derived family, member 4
Synonyms: 2010002L15Rik, RELP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 67709
Homologene: 41671
Alas1
Name: aminolevulinic acid synthase 1
Synonyms: 5-aminolevulinate synthase, ALAS-N, Alas-1, succinyl-CoA: glycine C-succinyl transferase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 11655
HGNC: HGNC:396
Homologene: 55478
Naa35
Name: N(alpha)-acetyltransferase 35, NatC auxiliary subunit
Synonyms: C030004C14Rik, A330021G12Rik, Mak10, A330027C19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 78689
Homologene: 5781
Fam13b
Name: family with sequence similarity 13, member B
Synonyms: 2610024E20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 225358
VEGA: 18
HGNC: HGNC:1335
Homologene: 9585
Slc4a4
Name: solute carrier family 4 (anion exchanger), member 4
Synonyms: NBC1, NBC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 54403
Homologene: 55776
Hydin
Name: HYDIN, axonemal central pair apparatus protein
Synonyms: hyrh, hy3, hy-3, 1700034M11Rik, 4930545D19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 244653
Homologene: 52118
Sorcs1
Name: sortilin-related VPS10 domain containing receptor 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 58178
Homologene: 10967
Arhgap20
Name: Rho GTPase activating protein 20
Synonyms: 6530403F17Rik, A530023E23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 244867
Homologene: 18938
Cyp2c66
Name: cytochrome P450, family 2, subfamily c, polypeptide 66
Synonyms: 2010301M18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 69888
HGNC: HGNC:2623
Homologene: 133566
Lrp1b
Name: low density lipoprotein-related protein 1B
Synonyms: 9630004P12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 94217
HGNC: HGNC:6693
Homologene: 56810
Fbxw28
Name: F-box and WD-40 domain protein 28
Synonyms: Gm9337
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 668758
Homologene: 110776
Jakmip2
Name: janus kinase and microtubule interacting protein 2
Synonyms: D930046L20Rik, 6430702L21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 76217
VEGA: 18
Homologene: 8866
Syna
Name: syncytin a
Synonyms: Gm52, syncytin-A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 214292
Homologene: 86751
D130040H23Rik
Name: RIKEN cDNA D130040H23 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 211135
Homologene: 138403
Xkr4
Name: X-linked Kx blood group related 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 497097
Homologene: 45848
4930503B20Rik
Name: RIKEN cDNA 4930503B20 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 75015
Homologene: 41344
Tmbim7
Name: transmembrane BAX inhibitor motif containing 7
Synonyms: 4930403J02Rik, Lfg5, Tmbim1b, 4930511M11Rik, 4930500J03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 75010
Homologene: 81927
Zkscan16
Name: zinc finger with KRAB and SCAN domains 16
Synonyms: Zfp483
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100041581
Homologene: 26419
Vmn1r86
Name: vomeronasal 1 receptor 86
Synonyms: Gm10301
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 100312473
Homologene: 74345
Asz1
Name: ankyrin repeat, SAM and basic leucine zipper domain containing 1
Synonyms: Gasz, ORF3, 4933400N19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 74068
HGNC: HGNC:1350
Homologene: 11374
Atp8a2
Name: ATPase, aminophospholipid transporter-like, class I, type 8A, member 2
Synonyms: agil, Ib, wl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 50769
Homologene: 4443
Ccdc144b
Name: coiled-coil domain containing 144B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 241943
Homologene: 87263
4931428F04Rik
Name: RIKEN cDNA 4931428F04 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 74356
Homologene: 47588
Sdr16c5
Name: short chain dehydrogenase/reductase family 16C, member 5
Synonyms: Scdr9, Rdhe2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242285
Homologene: 15039
Atp8b2
Name: ATPase, class I, type 8B, member 2
Synonyms: Id
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 54667
Homologene: 23226
Olfr1418
Name: olfactory receptor 1418
Synonyms: MOR266-5, GA_x6K02T2RE5P-2207258-2206302
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 258227
Homologene: 79372
Casd1
Name: CAS1 domain containing 1
Synonyms: Cast1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 213819
Homologene: 11287
Map4k2
Name: mitogen-activated protein kinase kinase kinase kinase 2
Synonyms: Rab8ip, BL44
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 26412
HGNC: HGNC:6864
Homologene: 3370
Vmn1r212
Name: vomeronasal 1 receptor 212
Synonyms: V1rh18
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 171275
Homologene: 110880
Rnaseh2b
Name: ribonuclease H2, subunit B
Synonyms: Dleu8, 1110019N06Rik, 2610207P08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 67153
Homologene: 41572
Olfr1229
Name: olfactory receptor 1229
Synonyms: GA_x6K02T2Q125-50727797-50726862, MOR233-22, MOR233-19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 257921
Homologene: 79376
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 3,216,191 bp
  • A to T, chromosome 1 at 51,773,261 bp
  • T to C, chromosome 1 at 58,013,646 bp
  • T to C, chromosome 2 at 35,302,638 bp
  • A to T, chromosome 2 at 40,922,428 bp
  • A to G, chromosome 2 at 89,283,097 bp
  • A to G, chromosome 2 at 179,932,014 bp
  • A to G, chromosome 3 at 36,025,895 bp
  • A to T, chromosome 3 at 89,957,319 bp
  • A to T, chromosome 3 at 98,224,766 bp
  • A to T, chromosome 3 at 146,651,113 bp
  • T to A, chromosome 4 at 4,006,609 bp
  • C to T, chromosome 4 at 58,946,125 bp
  • A to T, chromosome 4 at 123,471,194 bp
  • C to T, chromosome 5 at 3,661,916 bp
  • A to G, chromosome 5 at 33,027,005 bp
  • A to G, chromosome 5 at 89,197,766 bp
  • T to A, chromosome 5 at 134,558,311 bp
  • C to A, chromosome 5 at 139,757,644 bp
  • T to A, chromosome 6 at 4,640,980 bp
  • A to G, chromosome 6 at 18,075,767 bp
  • T to A, chromosome 6 at 99,075,936 bp
  • T to C, chromosome 7 at 13,102,166 bp
  • C to T, chromosome 7 at 121,941,169 bp
  • T to A, chromosome 8 at 69,302,958 bp
  • T to A, chromosome 8 at 105,283,288 bp
  • T to A, chromosome 8 at 110,509,079 bp
  • A to T, chromosome 9 at 51,816,837 bp
  • G to T, chromosome 9 at 99,875,583 bp
  • G to T, chromosome 9 at 106,241,801 bp
  • G to A, chromosome 9 at 108,069,103 bp
  • A to C, chromosome 9 at 109,326,721 bp
  • A to C, chromosome 10 at 24,777,949 bp
  • A to G, chromosome 12 at 64,957,559 bp
  • T to C, chromosome 13 at 22,883,897 bp
  • C to T, chromosome 13 at 59,607,295 bp
  • A to G, chromosome 13 at 117,273,062 bp
  • A to T, chromosome 14 at 33,934,481 bp
  • C to A, chromosome 14 at 60,026,140 bp
  • A to C, chromosome 14 at 62,360,457 bp
  • A to T, chromosome 15 at 101,035,498 bp
  • A to G, chromosome 16 at 45,096,621 bp
  • A to G, chromosome 18 at 31,583,672 bp
  • T to C, chromosome 18 at 34,462,955 bp
  • A to T, chromosome 18 at 43,549,686 bp
  • G to T, chromosome 19 at 6,341,928 bp
  • T to C, chromosome 19 at 11,855,587 bp
  • T to C, chromosome 19 at 39,142,278 bp
  • A to G, chromosome 19 at 50,176,044 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3896 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040807-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.