Strain Name:
C57BL/6J-MtgxR3909Btlr/Mmmh
Stock Number:
040814-MU
Citation ID:
RRID:MMRRC_040814-MU
Other Names:
R3909 (G1), C57BL/6J-MtgxR3909Btlr
Major Collection:

Gene Information

Atrn
Name: attractin
Synonyms: Mgca
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 11990
HGNC: HGNC:885
Homologene: 22542
Fn1
Name: fibronectin 1
Synonyms: Fn-1, Fn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 14268
HGNC: HGNC:3778
Homologene: 1533
Casp8
Name: caspase 8
Synonyms: Mch5, MACH, FLICE, Caspase-8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12370
HGNC: HGNC:1509
Homologene: 7657
Lasp1
Name: LIM and SH3 protein 1
Synonyms: SH3P6, Def-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 16796
HGNC: HGNC:6513
Homologene: 4480
Kmt2e
Name: lysine (K)-specific methyltransferase 2E
Synonyms: 1810033J14Rik, D230038D11Rik, 9530077A04Rik, Mll5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 69188
Homologene: 18822
Arid4b
Name: AT rich interactive domain 4B (RBP1-like)
Synonyms: RBBP1L1, SAP180, BRCAA1, Rbp1l1, 6720480E17Rik, 6330417L24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 94246
Homologene: 12847
Arhgap39
Name: Rho GTPase activating protein 39
Synonyms: D15Wsu169e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223666
Homologene: 27825
Rlf
Name: rearranged L-myc fusion sequence
Synonyms: 9230110M18Rik, MommeD8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 109263
Homologene: 8243
Golga4
Name: golgi autoantigen, golgin subfamily a, 4
Synonyms: golgin-245, Olp-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 54214
HGNC: HGNC:4427
Homologene: 68224
Ankrd12
Name: ankyrin repeat domain 12
Synonyms: ANCO-2, GAC-1, 2900001A12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 106585
Homologene: 9059
Fbxl17
Name: F-box and leucine-rich repeat protein 17
Synonyms: Fbx13, C130023C01Rik, 6330576B01Rik, Fbxo13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 50758
Homologene: 79859
Trim66
Name: tripartite motif-containing 66
Synonyms: D7H11orf29, Tif1d
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 330627
Homologene: 28044
Crim1
Name: cysteine rich transmembrane BMP regulator 1 (chordin like)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 50766
VEGA: 17
HGNC: HGNC:2359
Homologene: 9510
Hyls1
Name: HYLS1, centriolar and ciliogenesis associated
Synonyms: 3010015K02Rik, hydrolethalus syndrome 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 76832
Homologene: 82283
Acsl5
Name: acyl-CoA synthetase long-chain family member 5
Synonyms: 1700030F05Rik, Facl5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 433256
VEGA: 19
Homologene: 69208
Psmd2
Name: proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
Synonyms: TEG-190, Tex190, 9430095H01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 21762
HGNC: HGNC:9559
Homologene: 2101
Copg1
Name: coatomer protein complex, subunit gamma 1
Synonyms: D6Ertd71e, D6Wsu16e, Copg
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 54161
HGNC: HGNC:2236
Homologene: 56745
Dcbld1
Name: discoidin, CUB and LCCL domain containing 1
Synonyms: 4631413K11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 66686
Homologene: 12010
Zfc3h1
Name: zinc finger, C3H1-type containing
Synonyms: Psrc2, Ccdc131
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216345
Homologene: 17017
Hspa1a
Name: heat shock protein 1A
Synonyms: Hsp70.3, Hsp70-3, Hsp68, Hsp70a1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 193740
Homologene: 74294
Scn1a
Name: sodium channel, voltage-gated, type I, alpha
Synonyms: Nav1.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20265
Homologene: 21375
Muc4
Name: mucin 4
Synonyms: 4933405I11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 140474
HGNC: HGNC:7514
Homologene: 124469
Olfr1251
Name: olfactory receptor 1251
Synonyms: GA_x6K02T2Q125-51109312-51108356, MOR231-15P, MOR231-24_p
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 259145
Homologene: 74065
Cngb3
Name: cyclic nucleotide gated channel beta 3
Synonyms: CNG6, CCNC2, Cngbeta2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 30952
HGNC: HGNC:2153
Homologene: 40908
Ryr3
Name: ryanodine receptor 3
Synonyms: calcium release channel isoform 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20192
Homologene: 68151
Cacna1s
Name: calcium channel, voltage-dependent, L type, alpha 1S subunit
Synonyms: Cchl1a3, fmd, mdg, sj, muscle dysgenesis, Cav1.1, DHPR alpha1s
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12292
HGNC: HGNC:1397
Homologene: 37257
A2m
Name: alpha-2-macroglobulin
Synonyms: A2mp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232345
HGNC: HGNC:7
Homologene: 37248
Olfr304
Name: olfactory receptor 304
Synonyms: GA_x6K02T2NHDJ-9721756-9722757, MOR219-3P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258089
Homologene: 121542
Muc5b
Name: mucin 5, subtype B, tracheobronchial
Synonyms: MUC9, MUC5, 2300002I04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 74180
HGNC: HGNC:7516
Homologene: 136756
Mug1
Name: murinoglobulin 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 17836
Homologene: 136663
Olfr1153
Name: olfactory receptor 1153
Synonyms: GA_x6K02T2Q125-49395950-49396882, MOR177-7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258633
Homologene: 27230
Gbp3
Name: guanylate binding protein 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 55932
Homologene: 137329
Alk
Name: anaplastic lymphoma kinase
Synonyms: Tcrz, CD246
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 11682
VEGA: 17
HGNC: HGNC:427
Homologene: 68387
F11
Name: coagulation factor XI
Synonyms: plasma thromboplastin antecedent, FXI, Cf11, 1600027G01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 109821
HGNC: HGNC:3529
Homologene: 86654
Olfr1143
Name: olfactory receptor 1143
Synonyms: GA_x6K02T2Q125-49303473-49304405, MOR177-14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258290
Homologene: 74079
Prdm13
Name: PR domain containing 13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230025
Homologene: 11000
Prps1l1
Name: phosphoribosyl pyrophosphate synthetase 1-like 1
Synonyms: 1700011K15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 75456
HGNC: HGNC:9463
Homologene: 75282
Cacng1
Name: calcium channel, voltage-dependent, gamma subunit 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 12299
HGNC: HGNC:1405
Homologene: 582
Mxd1
Name: MAX dimerization protein 1
Synonyms: Mad, Mad1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 17119
HGNC: HGNC:6761
Homologene: 1767
Vmn2r38
Name: vomeronasal 2, receptor 38
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 434110
Homologene: 113703
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 58,844,811 bp
  • C to T, chromosome 1 at 71,607,913 bp
  • T to A, chromosome 1 at 136,084,269 bp
  • T to A, chromosome 2 at 66,273,988 bp
  • T to A, chromosome 2 at 87,802,687 bp
  • T to A, chromosome 2 at 87,896,949 bp
  • T to C, chromosome 2 at 89,667,013 bp
  • T to C, chromosome 2 at 112,636,608 bp
  • T to A, chromosome 2 at 130,994,207 bp
  • C to T, chromosome 3 at 142,566,338 bp
  • G to A, chromosome 4 at 19,461,679 bp
  • A to G, chromosome 4 at 21,685,498 bp
  • G to A, chromosome 4 at 121,149,032 bp
  • A to G, chromosome 5 at 23,501,626 bp
  • G to T, chromosome 6 at 86,650,960 bp
  • T to C, chromosome 6 at 87,892,195 bp
  • T to A, chromosome 6 at 121,648,166 bp
  • T to C, chromosome 6 at 121,873,604 bp
  • T to C, chromosome 7 at 9,075,554 bp
  • T to A, chromosome 7 at 86,385,974 bp
  • C to T, chromosome 7 at 109,458,815 bp
  • C to T, chromosome 7 at 141,849,498 bp
  • A to G, chromosome 8 at 45,248,638 bp
  • T to C, chromosome 9 at 35,561,409 bp
  • A to G, chromosome 9 at 118,558,736 bp
  • T to G, chromosome 10 at 52,319,470 bp
  • T to C, chromosome 10 at 115,419,901 bp
  • G to A, chromosome 11 at 97,799,827 bp
  • C to A, chromosome 11 at 107,716,292 bp
  • A to T, chromosome 12 at 34,985,798 bp
  • T to C, chromosome 13 at 14,132,484 bp
  • A to G, chromosome 15 at 76,751,888 bp
  • A to G, chromosome 16 at 20,655,642 bp
  • G to C, chromosome 16 at 32,753,919 bp
  • C to T, chromosome 17 at 34,971,727 bp
  • G to A, chromosome 17 at 63,499,807 bp
  • G to T, chromosome 17 at 65,984,005 bp
  • T to C, chromosome 17 at 71,897,911 bp
  • C to T, chromosome 17 at 78,281,239 bp
  • G to A, chromosome 19 at 55,283,399 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3909 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
040814-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.