Strain Name:
C57BL/6J-MtgxR3929Btlr/Mmmh
Stock Number:
040824-MU
Citation ID:
RRID:MMRRC_040824-MU
Other Names:
R3929 (G1), C57BL/6J-MtgxR3929Btlr
Major Collection:

Gene Information

Trmo
Name: tRNA methyltransferase O
Synonyms: 5830415F09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 74753
Homologene: 32316
Xrn1
Name: 5'-3' exoribonuclease 1
Synonyms: mXrn1, Dhm2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 24127
Homologene: 5894
Morf4l1
Name: mortality factor 4 like 1
Synonyms: TEG-189, MRG15, MORFRG15, Tex189
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 21761
Homologene: 86043
Ctage5
Name: CTAGE family, member 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Cabin1
Name: calcineurin binding protein 1
Synonyms: Ppp3in, Cain, A330070M20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 104248
VEGA: 10
Homologene: 49307
Atrx
Name: ATRX, chromatin remodeler
Synonyms: DXHXS6677E, Rad54, Hp1bp2, XH2, Xnp, HP1-BP38, 4833408C14Rik, alpha thalassemia/mental retardation syndrome X-linked
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 22589
HGNC: HGNC:886
Homologene: 416
Ccnf
Name: cyclin F
Synonyms: CycF, Fbxo1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 12449
VEGA: 17
HGNC: HGNC:1591
Homologene: 1335
Sin3a
Name: transcriptional regulator, SIN3A (yeast)
Synonyms: Sin3, mSin3A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 20466
Homologene: 32124
Tbl1xr1
Name: transducin (beta)-like 1X-linked receptor 1
Synonyms: Ira1, TBLR1, DC42, C21, C230089I12Rik, A630076E03Rik, 8030499H02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 81004
Homologene: 69382
Ppp2r1a
Name: protein phosphatase 2, regulatory subunit A, alpha
Synonyms: PR65, protein phosphatase PP2A, 6330556D22Rik, PP2A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 51792
HGNC: HGNC:9302
Homologene: 68559
Ctps
Name: cytidine 5'-triphosphate synthase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 51797
HGNC: HGNC:2519
Homologene: 20446
Tnrc6c
Name: trinucleotide repeat containing 6C
Synonyms: 9930033H14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217351
Homologene: 23137
Tarsl2
Name: threonyl-tRNA synthetase-like 2
Synonyms: A530046H20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 272396
Homologene: 65036
Prdm10
Name: PR domain containing 10
Synonyms: tristanin, LOC382066
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 382066
Homologene: 45718
Muc5ac
Name: mucin 5, subtypes A and C, tracheobronchial/gastric
Synonyms: MGM, 2210005L13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 17833
HGNC: HGNC:7515
Homologene: 137237
Itpr2
Name: inositol 1,4,5-triphosphate receptor 2
Synonyms: Ip3r2, Itpr5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 16439
HGNC: HGNC:6181
Homologene: 37593
Zim1
Name: zinc finger, imprinted 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 22776
Homologene: 129793
Nav3
Name: neuron navigator 3
Synonyms: Pomfil1p, POMFIL1, 4732483H20Rik, unc53H3, steerin 3, 9630020C08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 260315
Homologene: 56688
Vmn2r19
Name: vomeronasal 2, receptor 19
Synonyms: EG232358
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232358
Homologene: 84037
Stap2
Name: signal transducing adaptor family member 2
Synonyms: STAP-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 106766
VEGA: 17
Homologene: 9798
Me3
Name: malic enzyme 3, NADP(+)-dependent, mitochondrial
Synonyms: B230207H15Rik, 1700020C08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 109264
HGNC: HGNC:6985
Homologene: 100773
Rp1
Name: retinitis pigmentosa 1 (human)
Synonyms: oxygen-regulated protein 1, Orp1, mG145, Dcdc3, Rp1h
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 19888
Homologene: 4564
H1f8
Name: H1.8 linker histone
Synonyms: H1oo, H1foo, H1-8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 171506
Homologene: 51377
Olfr1105
Name: olfactory receptor 1105
Synonyms: GA_x6K02T2Q125-48521031-48520093, MOR172-7, MOR0-6P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258085
Homologene: 121541
Stkld1
Name: serine/threonine kinase-like domain containing 1
Synonyms: LOC279029, Gm711
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 279029
Homologene: 19586
Olfr1331
Name: olfactory receptor 1331
Synonyms: GA_x6K02T2QD9B-18670866-18669913, MOR259-3P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 258159
Homologene: 134082
E230025N22Rik
Name: Riken cDNA E230025N22 gene
Synonyms: EG240216
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 240216
Homologene: 131194
Dmrta1
Name: doublesex and mab-3 related transcription factor like family A1
Synonyms: Dmrt4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242523
Homologene: 18477
Olfr1390
Name: olfactory receptor 1390
Synonyms: GA_x6K02T2QP88-6094111-6093176, MOR256-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 259068
Trim61
Name: tripartite motif-containing 61
Synonyms: 2czf61, E330039K03Rik, Rnf35
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 260296
Vmn1r61
Name: vomeronasal 1 receptor 61
Synonyms: Gm7186
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 636731
Homologene: 41799
C9
Name: complement component 9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 12279
HGNC: HGNC:1358
Homologene: 74406
Olfr644
Name: olfactory receptor 644
Synonyms: GA_x6K02T2PBJ9-6803062-6802118, MOR13-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259125
Homologene: 17491
St6gal2
Name: beta galactoside alpha 2,6 sialyltransferase 2
Synonyms: C230064G14Rik, ST6Gal II
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 240119
Homologene: 13052
Klhl40
Name: kelch-like 40
Synonyms: 2310024D23Rik, Kbtbd5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 72330
VEGA: 9
Homologene: 17571
Olfr791
Name: olfactory receptor 791
Synonyms: GA_x6K02T2PULF-11205096-11206034, MOR114-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 258932
Homologene: 71950
Rpusd4
Name: RNA pseudouridylate synthase domain containing 4
Synonyms: 2410001E19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 71989
Homologene: 32794
Ak5
Name: adenylate kinase 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229949
HGNC: HGNC:365
Homologene: 76103
Dram1
Name: DNA-damage regulated autophagy modulator 1
Synonyms: 1200002N14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 71712
Homologene: 41255
AC079644.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Fam229a
Name: family with sequence similarity 229, member A
Synonyms: 1700125D06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 68233
Homologene: 47789
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 4,352,645 bp
  • T to A, chromosome 2 at 26,940,047 bp
  • T to A, chromosome 2 at 87,034,084 bp
  • G to C, chromosome 3 at 22,189,768 bp
  • A to C, chromosome 3 at 152,667,807 bp
  • C to T, chromosome 4 at 46,382,647 bp
  • C to T, chromosome 4 at 89,691,444 bp
  • T to C, chromosome 4 at 118,868,982 bp
  • T to A, chromosome 4 at 120,541,896 bp
  • A to G, chromosome 4 at 129,491,411 bp
  • A to G, chromosome 6 at 115,948,796 bp
  • T to C, chromosome 6 at 123,315,628 bp
  • C to A, chromosome 6 at 146,374,359 bp
  • A to G, chromosome 7 at 5,611,177 bp
  • A to G, chromosome 7 at 6,682,189 bp
  • A to G, chromosome 7 at 65,684,043 bp
  • T to C, chromosome 7 at 89,833,690 bp
  • C to T, chromosome 7 at 104,068,584 bp
  • T to C, chromosome 7 at 141,802,892 bp
  • A to G, chromosome 8 at 65,013,317 bp
  • T to C, chromosome 9 at 31,347,136 bp
  • A to G, chromosome 9 at 35,272,580 bp
  • A to G, chromosome 9 at 57,118,137 bp
  • A to G, chromosome 9 at 90,110,122 bp
  • T to C, chromosome 9 at 95,988,873 bp
  • A to G, chromosome 9 at 121,780,676 bp
  • T to C, chromosome 10 at 75,751,618 bp
  • A to T, chromosome 10 at 88,340,505 bp
  • A to G, chromosome 10 at 109,684,203 bp
  • G to A, chromosome 10 at 129,526,231 bp
  • A to T, chromosome 11 at 49,340,993 bp
  • C to T, chromosome 11 at 117,723,529 bp
  • G to T, chromosome 12 at 59,188,296 bp
  • A to T, chromosome 12 at 88,083,707 bp
  • T to A, chromosome 15 at 6,467,458 bp
  • A to T, chromosome 17 at 20,945,592 bp
  • A to G, chromosome 17 at 24,234,382 bp
  • A to G, chromosome 17 at 55,496,323 bp
  • A to C, chromosome 17 at 56,003,156 bp
  • T to C, chromosome 18 at 36,691,572 bp
  • T to C, chromosome X at 105,879,917 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3929 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040824-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.