Strain Name:
C57BL/6J-MtgxR3980Btlr/Mmmh
Stock Number:
040843-MU
Citation ID:
RRID:MMRRC_040843-MU
Other Names:
R3980 (G1), C57BL/6J-MtgxR3980Btlr
Major Collection:

Strain Information

Hgs
Name: HGF-regulated tyrosine kinase substrate
Synonyms: tn, Hrs
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 15239
HGNC: HGNC:4897
Homologene: 37954
Map7
Name: microtubule-associated protein 7
Synonyms: ste, Mtap7, mste, mshi, E-MAP-115
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 17761
VEGA: 10
HGNC: HGNC:6869
Homologene: 20851
Kdm5b
Name: lysine demethylase 5B
Synonyms: Rb-Bp2, 2210016I17Rik, Jarid1b, 2010009J12Rik, D1Ertd202e, Plu1, PLU-1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 75605
Homologene: 48448
Rnf111
Name: ring finger 111
Synonyms: Arkadia
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 93836
VEGA: 9
Homologene: 9741
Mcmbp
Name: minichromosome maintenance complex binding protein
Synonyms: 1110007A13Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 210711
Homologene: 11749
Sik3
Name: SIK family kinase 3
Synonyms: 9030204A07Rik, 5730525O22Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 70661
Homologene: 57023
Depdc5
Name: DEP domain containing 5
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 277854
Homologene: 34718
Lmnb1
Name: lamin B1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 16906
HGNC: HGNC:6637
Homologene: 55912
Copz1
Name: coatomer protein complex, subunit zeta 1
Synonyms: nonclathrin coat protein zeta1-COP, 5930435A22Rik, D4Ertd360e
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 56447
VEGA: 15
HGNC: HGNC:2243
Homologene: 9366
Gabpb2
Name: GA repeat binding protein, beta 2
Synonyms: Gabpb2-1, 1810015F01Rik, 9430006E19Rik, A430024B14Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 213054
Homologene: 34921
Rapgef1
Name: Rap guanine nucleotide exchange factor (GEF) 1
Synonyms: Grf2, 4932418O06Rik, C3G
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 107746
HGNC: HGNC:4568
Homologene: 50501
Rttn
Name: rotatin
Synonyms: 4921538A15Rik, C530033I08Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 246102
VEGA: 18
Homologene: 65275
Tshr
Name: thyroid stimulating hormone receptor
Synonyms: hyt, hypothroid, pet
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 22095
Homologene: 315
Stx7
Name: syntaxin 7
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 53331
VEGA: 10
Homologene: 37823
Wbp1l
Name: WW domain binding protein 1 like
Synonyms: D19Wsu162e
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 226178
Homologene: 9839
Gm9631
Name: predicted gene 9631
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 674842
VEGA: 11
Prpf39
Name: pre-mRNA processing factor 39
Synonyms: Srcs1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 328110
Homologene: 32377
Glb1
Name: galactosidase, beta 1
Synonyms: Bge, Bgt, Bgl-t, C130097A14Rik, Bgl-e, Bgl-s, Bgl, Bgs
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 12091
VEGA: 9
HGNC: HGNC:4298
Homologene: 47922
Eif2a
Name: eukaryotic translation initiation factor 2A
Synonyms: D3Ertd194e
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229317
HGNC: HGNC:3254
Homologene: 5969
Yme1l1
Name: YME1-like 1 (S. cerevisiae)
Synonyms: ATP-dependent metalloprotease FtsH1, Ftsh
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 27377
Homologene: 31996
Mpp7
Name: membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
Synonyms: 5430426E14Rik, LOC381166, 2810038M04Rik, 1110068J02Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 75739
VEGA: 18
Homologene: 1455
Klhl2
Name: kelch-like 2, Mayven
Synonyms: Mav, ABP-KELCH, 6030411N21Rik, 8530402H02Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 77113
HGNC: HGNC:6353
Homologene: 21416
Plxna2
Name: plexin A2
Synonyms: OCT, Plxn2, 2810428A13Rik, PlexA2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 18845
HGNC: HGNC:9100
Homologene: 56427
Csmd1
Name: CUB and Sushi multiple domains 1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 94109
Homologene: 69536
Ctnnd2
Name: catenin delta 2
Synonyms: Nprap, catenin (cadherin associated protein), delta 2, Catnd2, neurojugin
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 18163
VEGA: 15
HGNC: HGNC:2516
Homologene: 55574
Pou4f2
Name: POU domain, class 4, transcription factor 2
Synonyms: Brn-3.2, Pou4f-rs1, Brn-3b, mBrn3-3R, Brn3b
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 18997
HGNC: HGNC:9219
Homologene: 20959
Csk
Name: c-src tyrosine kinase
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 12988
VEGA: 9
HGNC: HGNC:2444
Homologene: 55818
Pigo
Name: phosphatidylinositol glycan anchor biosynthesis, class O
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 56703
Homologene: 31761
Nos3
Name: nitric oxide synthase 3, endothelial cell
Synonyms: ecNOS, 2310065A03Rik, eNOS, Nos-3
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 18127
HGNC: HGNC:7876
Homologene: 504
Kidins220
Name: kinase D-interacting substrate 220
Synonyms: 3110039L19Rik, C330002I19Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 77480
VEGA: 12
Homologene: 14254
Nlrp1b
Name: NLR family, pyrin domain containing 1B
Synonyms: Nalp1b
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 637515
Homologene: 19080
Loxhd1
Name: lipoxygenase homology domains 1
Synonyms: 1700096C21Rik, sba
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 240411
Arhgef25
Name: Rho guanine nucleotide exchange factor 25
Synonyms: GEFT, D10Ertd610e, 2410008H17Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 52666
VEGA: 10
Homologene: 32691
Obscn
Name: obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Synonyms: OTTMUSG00000005786, LOC380698
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 380698
Homologene: 70869
Esyt1
Name: extended synaptotagmin-like protein 1
Synonyms: vp115, Mbc2, Fam62a
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 23943
VEGA: 10
Homologene: 40794
4930458L03Rik
Name:
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Plcb3
Name: phospholipase C, beta 3
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 18797
VEGA: 19
HGNC: HGNC:9056
Homologene: 47960
Parp3
Name: poly (ADP-ribose) polymerase family, member 3
Synonyms: Adprt3, PARP-3, A930002C11Rik, Adprtl3
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235587
HGNC: HGNC:273
Homologene: 4005
Ankhd1
Name: ankyrin repeat and KH domain containing 1
Synonyms: 9130019P20Rik, 4933432B13Rik, A530027J04Rik, 1110004O12Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 108857
Homologene: 87006
AC092752.1
Name:
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
4932441B19Rik
Name:
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Or10ak12
Name: olfactory receptor family 10 subfamily AK member 12
Synonyms: GA_x6K02T2QD9B-18726774-18727577, MOR259-5, Olfr1335, MOR259-12, GA_x6K02T2QD9B-18723799-18724749, Olfr1334-ps1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 435804
Homologene: 138635
Kcnt1
Name: potassium channel, subfamily T, member 1
Synonyms: Slack, C030030G16Rik, slo2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227632
Homologene: 11055
Col4a1
Name: collagen, type IV, alpha 1
Synonyms: Del(8)44H, Raw, Svc, Bru, alpha1(IV) collagen, Del(8)Bru44H, Col4a-1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 12826
HGNC: HGNC:2202
Homologene: 20437
Nuggc
Name: nuclear GTPase, germinal center associated
Synonyms: LOC239151, Gm600, SLIP-GC
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 100503545
Homologene: 72641
Nrap
Name: nebulin-related anchoring protein
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 18175
HGNC: HGNC:7988
Homologene: 4499
Plch2
Name: phospholipase C, eta 2
Synonyms: A930027K05Rik, PLCeta2, Plcl4
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 269615
Homologene: 85172
Bean1
Name: brain expressed, associated with Nedd4, 1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 65115
Homologene: 110172
Dab2
Name: disabled 2, mitogen-responsive phosphoprotein
Synonyms: 5730435J12Rik, p96, D15Wsu122e, D630005B22Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 13132
HGNC: HGNC:2662
Homologene: 1026
Stat6
Name: signal transducer and activator of transcription 6
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 20852
Homologene: 2373
Adgrb1
Name: adhesion G protein-coupled receptor B1
Synonyms: B830018M07Rik, Bai1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 107831
HGNC: HGNC:943
Homologene: 1287
Sphkap
Name: SPHK1 interactor, AKAP domain containing
Synonyms: 4930544G21Rik, SKIP, A930009L15Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 77629
Homologene: 18172
Ccr9
Name: C-C motif chemokine receptor 9
Synonyms: GPR-9-6, Cmkbr10
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 12769
HGNC: HGNC:1610
Homologene: 22546
Vmn1r5
Name: vomeronasal 1 receptor 5
Synonyms: V1rc19
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 171192
Homologene: 128340
Insyn2b
Name: inhibitory synaptic factor family member 2B
Synonyms: Fam196b, Gm6041
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 574403
VEGA: 11
Homologene: 107175
Slc22a14
Name: solute carrier family 22 (organic cation transporter), member 14
Synonyms: LOC382113
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 382113
HGNC: HGNC:8495
Homologene: 3530
Plekhg6
Name: pleckstrin homology domain containing, family G (with RhoGef domain) member 6
Synonyms: LOC213522
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 213522
Homologene: 32395
Tas2r103
Name: taste receptor, type 2, member 103
Synonyms: mt2r63, Tas2r3, Tas2r10, T2R3, mGR03, EG667992, TRB2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 667992
Homologene: 130076
Tfap2d
Name: transcription factor AP-2, delta
Synonyms: Tcfap2d
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226896
Homologene: 17700
Krt31
Name: keratin 31
Synonyms: Ha1, Kha1, MKHA-1, Krt1-1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 16660
HGNC: HGNC:6448
Homologene: 74433
Skint4
Name: selection and upkeep of intraepithelial T cells 4
Synonyms: 9530098N22Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 320640
Amacr
Name: alpha-methylacyl-CoA racemase
Synonyms: 2-arylpropionyl-CoA epimerase, Macr1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 17117
VEGA: 15
HGNC: HGNC:451
Homologene: 7410
Or51a25
Name: olfactory receptor family 51 subfamily A member 25
Synonyms: GA_x6K02T2PBJ9-5441154-5440198, MOR11-1, Olfr559
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 259116
Homologene: 74124
Defb30
Name: defensin beta 30
Synonyms: 2410125J01Rik, 4930449O14Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 73670
Homologene: 86862
Slc36a3
Name: solute carrier family 36 (proton/amino acid symporter), member 3
Synonyms: tramdorin2, PAT3, TRAMD2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 215332
Homologene: 76175
Mn1
Name: meningioma 1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 433938
HGNC: HGNC:7180
Homologene: 37620
Vmn1r32
Name: vomeronasal 1 receptor 32
Synonyms: V1rc15
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 171188
Homologene: 115644
Cutal
Name: cutA divalent cation tolerance homolog-like
Synonyms: D730039F16Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 77996
Homologene: 66286
Cybb
Name: cytochrome b-245, beta polypeptide
Synonyms: gp91phox, Nox2, gp91phox, Cgd
Type: Gene
Species: Mouse
Chromosome: X
NCBI: 13058
HGNC: HGNC:2578
Homologene: 68054
Dcun1d4
Name: defective in cullin neddylation 1 domain containing 4
Synonyms: DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae)
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100737
Homologene: 22867
Phc3
Name: polyhomeotic 3
Synonyms: EDR3, HPH3, E030046K01Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 241915
Homologene: 69390
Tada2a
Name: transcriptional adaptor 2A
Synonyms: Tada2l, D030022J10Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217031
Homologene: 38834
Oasl1
Name: 2'-5' oligoadenylate synthetase-like 1
Synonyms: 7530414C13Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231655
HGNC: HGNC:8090
Homologene: 2769
Ceacam16
Name: CEA cell adhesion molecule 16
Synonyms: LOC330483
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 330483
Homologene: 19857
Rdh14
Name: retinol dehydrogenase 14 (all-trans and 9-cis)
Synonyms: PAN2, 3110030G19Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 105014
VEGA: 12
Homologene: 75139
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 19,165,963 bp
  • A to T, chromosome 1 at 83,267,494 bp
  • A to G, chromosome 1 at 134,619,670 bp
  • C to T, chromosome 1 at 194,749,317 bp
  • T to C, chromosome 2 at 23,187,771 bp
  • T to C, chromosome 2 at 25,893,214 bp
  • G to A, chromosome 2 at 29,719,650 bp
  • T to C, chromosome 2 at 34,882,313 bp
  • T to A, chromosome 3 at 30,936,931 bp
  • T to C, chromosome 3 at 58,539,539 bp
  • A to T, chromosome 3 at 95,188,770 bp
  • A to G, chromosome 4 at 43,019,231 bp
  • T to A, chromosome 4 at 112,124,680 bp
  • T to A, chromosome 4 at 118,809,303 bp
  • T to C, chromosome 4 at 154,984,798 bp
  • T to A, chromosome 5 at 24,377,931 bp
  • T to C, chromosome 5 at 32,926,875 bp
  • G to T, chromosome 5 at 73,520,112 bp
  • A to T, chromosome 5 at 111,421,770 bp
  • C to T, chromosome 5 at 114,932,898 bp
  • A to G, chromosome 6 at 56,985,651 bp
  • T to A, chromosome 6 at 66,553,714 bp
  • C to A, chromosome 6 at 125,373,183 bp
  • A to G, chromosome 6 at 133,036,317 bp
  • A to T, chromosome 7 at 14,473,409 bp
  • A to G, chromosome 7 at 19,858,633 bp
  • T to C, chromosome 7 at 102,723,752 bp
  • A to G, chromosome 7 at 128,698,583 bp
  • T to C, chromosome 8 at 11,239,155 bp
  • T to A, chromosome 8 at 15,906,056 bp
  • A to T, chromosome 8 at 64,743,075 bp
  • C to A, chromosome 8 at 64,743,081 bp
  • G to T, chromosome 8 at 78,435,438 bp
  • A to T, chromosome 8 at 104,211,098 bp
  • G to A, chromosome 9 at 46,202,063 bp
  • A to G, chromosome 9 at 57,630,780 bp
  • A to T, chromosome 9 at 70,442,325 bp
  • T to C, chromosome 9 at 106,474,068 bp
  • T to A, chromosome 9 at 114,417,064 bp
  • T to C, chromosome 9 at 119,178,486 bp
  • A to T, chromosome 9 at 123,779,376 bp
  • C to A, chromosome 10 at 20,267,353 bp
  • T to C, chromosome 10 at 24,185,049 bp
  • C to A, chromosome 10 at 127,187,220 bp
  • T to C, chromosome 10 at 127,655,379 bp
  • T to A, chromosome 10 at 128,511,524 bp
  • G to A, chromosome 11 at 34,402,678 bp
  • G to A, chromosome 11 at 55,135,383 bp
  • A to G, chromosome 11 at 59,124,803 bp
  • A to T, chromosome 11 at 71,181,611 bp
  • A to T, chromosome 11 at 84,103,120 bp
  • G to T, chromosome 11 at 100,048,204 bp
  • C to T, chromosome 11 at 120,477,514 bp
  • A to G, chromosome 11 at 121,943,568 bp
  • A to G, chromosome 12 at 10,394,703 bp
  • T to C, chromosome 12 at 25,001,759 bp
  • T to C, chromosome 12 at 65,061,457 bp
  • C to A, chromosome 12 at 91,537,743 bp
  • A to T, chromosome 13 at 64,922,654 bp
  • A to G, chromosome 13 at 65,035,160 bp
  • C to A, chromosome 14 at 63,035,972 bp
  • T to C, chromosome 14 at 65,619,093 bp
  • A to G, chromosome 15 at 6,435,163 bp
  • T to A, chromosome 15 at 10,988,929 bp
  • T to A, chromosome 15 at 30,669,443 bp
  • G to A, chromosome 15 at 74,582,943 bp
  • T to A, chromosome 15 at 103,289,184 bp
  • T to C, chromosome 18 at 7,444,062 bp
  • A to T, chromosome 18 at 36,647,613 bp
  • A to G, chromosome 18 at 56,731,019 bp
  • T to C, chromosome 18 at 77,414,159 bp
  • C to T, chromosome 18 at 89,017,275 bp
  • A to G, chromosome 19 at 6,966,435 bp
  • T to A, chromosome 19 at 46,653,957 bp
  • G to A, chromosome 19 at 56,381,552 bp
  • T to C, chromosome X at 9,444,588 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3980 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
040843-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.