Strain Name:
C57BL/6J-MtgxR3799Btlr/Mmmh
Stock Number:
040877-MU
Citation ID:
RRID:MMRRC_040877-MU
Other Names:
R3799 (G1), C57BL/6J-MtgxR3799Btlr
Major Collection:

Strain Information

Fgfr1
Name: fibroblast growth factor receptor 1
Synonyms: Flt-2, Fgfr-1, Hspy, Eask, FGFR-I, Fr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 14182
HGNC: HGNC:3688
Homologene: 69065
Exog
Name: endo/exonuclease (5'-3'), endonuclease G-like
Synonyms: ENGL-a, ENDOGL2, ENGL-B, Endogl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 208194
VEGA: 9
HGNC: HGNC:3347
Homologene: 3745
Setd2
Name: SET domain containing 2
Synonyms: 4921524K10Rik, KMT3A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235626
Homologene: 56493
Nup214
Name: nucleoporin 214
Synonyms: D2H9S46E, CAN
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227720
HGNC: HGNC:8064
Homologene: 38008
Xdh
Name: xanthine dehydrogenase
Synonyms: Xox-1, Xox1, Xor, xanthine oxidase, XO
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 22436
VEGA: 17
Homologene: 324
Ralgapa1
Name: Ral GTPase activating protein, alpha subunit 1
Synonyms: 4930400K19Rik, Tulip1, 2310003F20Rik, Garnl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 56784
VEGA: 12
Homologene: 84805
Mastl
Name: microtubule associated serine/threonine kinase-like
Synonyms: THC2, 2700091H24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 67121
Homologene: 12086
Phrf1
Name: PHD and ring finger domains 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 101471
Homologene: 16377
Hjurp
Name: Holliday junction recognition protein
Synonyms: C330011F01Rik, A730008H23Rik, 6430706D22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 381280
Homologene: 10184
Adgrf3
Name: adhesion G protein-coupled receptor F3
Synonyms: LOC381628, PGR23, Gpr113
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 381628
Homologene: 17826
Calm1
Name: calmodulin 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 12313
Homologene: 116117
Glg1
Name: golgi apparatus protein 1
Synonyms: ESL-1, CFR, MG-160, MG160, CFR-1, Selel
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 20340
HGNC: HGNC:4316
Homologene: 7533
Cops7a
Name: COP9 signalosome subunit 7A
Synonyms: COP9 complex S7a, D6Ertd35e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 26894
Homologene: 22685
Trpa1
Name: transient receptor potential cation channel, subfamily A, member 1
Synonyms: ANKTM1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 277328
HGNC: HGNC:497
Homologene: 7189
Ush2a
Name: usherin
Synonyms: MUSH2A, A930011D15Rik, LOC381317, LOC269160, A930037M10Rik, Ushrn, Ush2a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 22283
Homologene: 66151
Dnah12
Name: dynein, axonemal, heavy chain 12
Synonyms: Hdhc3, HL-19, DLP12, HL19, DHC3, LOC380889, 4921531P07Rik, Dnahc7l, Dnahc12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 110083
HGNC: HGNC:2943
Homologene: 56821
Osbp2
Name: oxysterol binding protein 2
Synonyms: OSBPL1, ORP-4, 1700095P05Rik, C630001G20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 74309
HGNC: HGNC:8504
Homologene: 75303
Pard3b
Name: par-3 family cell polarity regulator beta
Synonyms: 2810455B10Rik, PAR3beta, PAR3L, PAR3B, 2010002N16Rik, Als2cr19, 1810008K04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 72823
Homologene: 35389
Vwa8
Name: von Willebrand factor A domain containing 8
Synonyms: 4932416F07Rik, 1300010F03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 219189
VEGA: 14
Homologene: 44881
Vmn2r25
Name: vomeronasal 2, receptor 25
Synonyms: EG545874
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 545874
Homologene: 135915
Mogat1
Name: monoacylglycerol O-acyltransferase 1
Synonyms: 0610030A14Rik, mDC2, MGAT1, Dgat2l1, 1110064N14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 68393
Homologene: 105237
Alpk3
Name: alpha-kinase 3
Synonyms: Midori
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 116904
Homologene: 10813
Nuggc
Name: nuclear GTPase, germinal center associated
Synonyms: LOC239151, SLIP-GC, Gm600
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 100503545
Homologene: 72641
Flnc
Name: filamin C, gamma
Synonyms: Fln2, 1110055E19Rik, actin binding protein 280
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 68794
HGNC: HGNC:3756
Homologene: 37481
Tcaf3
Name: TRPM8 channel-associated factor 3
Synonyms: Eapa2, Fam115e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 403088
Homologene: 74374
Ccna1
Name: cyclin A1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 12427
HGNC: HGNC:1577
Homologene: 31203
Zfp518a
Name: zinc finger protein 518A
Synonyms: 6330417C12Rik, 2810401C22Rik, Zfp518
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 72672
VEGA: 19
Homologene: 19378
Tmprss5
Name: transmembrane protease, serine 5 (spinesin)
Synonyms: spinesin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 80893
Homologene: 69471
A3galt2
Name: alpha 1,3-galactosyltransferase 2 (isoglobotriaosylceramide synthase)
Synonyms: LOC215493, iGb3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 215493
Homologene: 16326
Ehbp1l1
Name: EH domain binding protein 1-like 1
Synonyms: G430002G23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 114601
VEGA: 19
Homologene: 136059
Gm1527
Name: predicted gene 1527
Synonyms: LOC385263
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 385263
Homologene: 133976
Tmem8b
Name: transmembrane protein 8B
Synonyms: 4930500O05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242409
Homologene: 72894
Vmn2r76
Name: vomeronasal 2, receptor 76
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 675969
Homologene: 104330
Nans
Name: N-acetylneuraminic acid synthase (sialic acid synthase)
Synonyms: N-acetylneuraminic acid phosphate synthase, Sas, 4632418E04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 94181
Homologene: 10343
Paqr3
Name: progestin and adipoQ receptor family member III
Synonyms: 6330415A20Rik, RKTG
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231474
Homologene: 71077
Slc35g3
Name: solute carrier family 35, member G3
Synonyms: Amac1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 56293
Homologene: 89413
Tdpoz8
Name: TD and POZ domain containing 8
Synonyms: Gm4858
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229571
Homologene: 130121
Gm5799
Name: predicted gene 5799
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 108168155
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 14,893,264 bp
  • A to G, chromosome 1 at 62,161,229 bp
  • A to G, chromosome 1 at 78,529,138 bp
  • G to C, chromosome 1 at 88,277,215 bp
  • C to A, chromosome 1 at 188,626,567 bp
  • T to C, chromosome 2 at 23,140,492 bp
  • T to C, chromosome 2 at 32,034,682 bp
  • A to G, chromosome 3 at 28,926,596 bp
  • G to T, chromosome 3 at 55,050,619 bp
  • A to T, chromosome 3 at 93,074,086 bp
  • A to G, chromosome 4 at 43,673,892 bp
  • A to G, chromosome 4 at 46,492,839 bp
  • A to G, chromosome 4 at 128,767,070 bp
  • T to C, chromosome 5 at 30,196,823 bp
  • T to C, chromosome 5 at 97,111,316 bp
  • G to A, chromosome 6 at 29,443,739 bp
  • T to C, chromosome 6 at 42,597,080 bp
  • A to T, chromosome 6 at 123,853,184 bp
  • C to T, chromosome 6 at 124,959,832 bp
  • C to A, chromosome 7 at 81,092,753 bp
  • T to C, chromosome 7 at 86,226,036 bp
  • C to T, chromosome 7 at 141,259,918 bp
  • G to A, chromosome 8 at 25,572,437 bp
  • G to T, chromosome 8 at 111,173,273 bp
  • C to T, chromosome 9 at 49,102,837 bp
  • T to C, chromosome 9 at 110,549,571 bp
  • T to G, chromosome 9 at 119,449,810 bp
  • T to C, chromosome 11 at 3,717,883 bp
  • A to G, chromosome 11 at 69,760,917 bp
  • T to C, chromosome 12 at 55,659,130 bp
  • T to C, chromosome 12 at 100,205,602 bp
  • T to C, chromosome 14 at 26,770,923 bp
  • G to A, chromosome 14 at 43,543,693 bp
  • T to A, chromosome 14 at 65,619,638 bp
  • T to A, chromosome 14 at 79,064,896 bp
  • T to C, chromosome 17 at 73,907,658 bp
  • A to G, chromosome 19 at 5,719,115 bp
  • G to T, chromosome 19 at 40,915,310 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3799 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
040877-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.