Loading Mouse GIF
Loading...

Strain Name:
C57BL/6J-MtgxR3824Btlr/Mmmh
Stock Number:
040885-MU
Citation ID:
RRID:MMRRC_040885-MU
Other Names:
R3824 (G1), C57BL/6J-MtgxR3824Btlr
Major Collection:

Strain Information

St8sia1
Name: ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
Synonyms: alpha-2,8-sialyltransferase, ST8Sia I, GD3S, GD3 synthase, Siat8, Siat8a, 9330109E03Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 20449
Homologene: 2282
Slc12a1
Name: solute carrier family 12, member 1
Synonyms: Nkcc2, mBSC1, D630042G03Rik, urehr3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 20495
Homologene: 286
Arhgap12
Name: Rho GTPase activating protein 12
Synonyms: 2810011M08Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 75415
Homologene: 23089
Kat8
Name: K(lysine) acetyltransferase 8
Synonyms: D7Ertd629e, 5830450F21Rik, 2010203C02Rik, MOF, Myst1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 67773
Homologene: 41676
Taok3
Name: TAO kinase 3
Synonyms: A430105I05Rik, 2900006A08Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 330177
Homologene: 83279
Agrn
Name: agrin
Synonyms: NMF380, Agrin, nmf380
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 11603
HGNC: HGNC:329
Homologene: 27907
Fry
Name: FRY microtubule binding protein
Synonyms: cg003, 9330186A19Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 320365
Homologene: 113770
Nckap1
Name: NCK-associated protein 1
Synonyms: mh19, Hem-2, H19, Nap1, Hem2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 50884
HGNC: HGNC:7666
Homologene: 8384
Rack1
Name: receptor for activated C kinase 1
Synonyms: p205, GB-like, Gnb2-rs1, Gnb2l1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 14694
HGNC: HGNC:4399
Homologene: 4446
Ints8
Name: integrator complex subunit 8
Synonyms: D130008D20Rik, 2810013E07Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 72656
Homologene: 9888
Usp24
Name: ubiquitin specific peptidase 24
Synonyms: 2810030C21Rik, 2700066K03Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 329908
Homologene: 35420
Gls
Name: glutaminase
Synonyms: B230365M23Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 14660
HGNC: HGNC:4331
Homologene: 22726
Tmem259
Name: transmembrane protein 259
Synonyms: membralin, ORF61
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216157
Homologene: 14122
Drg2
Name: developmentally regulated GTP binding protein 2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 13495
HGNC: HGNC:3030
Homologene: 1061
Igfbp4
Name: insulin-like growth factor binding protein 4
Synonyms: Band 3A, IGFBP-4, Deb2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 16010
HGNC: HGNC:5473
Homologene: 1192
Ptk7
Name: PTK7 protein tyrosine kinase 7
Synonyms: 8430404F20Rik, mPTK7/CCK4, chz
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 71461
VEGA: 17
HGNC: HGNC:9618
Homologene: 43672
Ptprm
Name: protein tyrosine phosphatase receptor type M
Synonyms: RPTPmu
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 19274
VEGA: 17
HGNC: HGNC:9675
Homologene: 37694
Glmp
Name: glycosylated lysosomal membrane protein
Synonyms: NCU-G1, 0610031J06Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 56700
Homologene: 10562
2300002M23Rik
Name: RIKEN cDNA 2300002M23 gene
Synonyms: emprin
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 69542
Homologene: 49368
6030468B19Rik
Name: RIKEN cDNA 6030468B19 gene
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 77727
Homologene: 90660
9430015G10Rik
Name: RIKEN cDNA 9430015G10 gene
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230996
Homologene: 51678
Acsl5
Name: acyl-CoA synthetase long-chain family member 5
Synonyms: 1700030F05Rik, Facl5
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 433256
VEGA: 19
Homologene: 69208
Zfp12
Name: zinc finger protein 12
Synonyms: Krox-7, Zfp-12
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231866
Homologene: 65328
Myo19
Name: myosin XIX
Synonyms: 1110055A02Rik, Myohd1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 66196
Homologene: 49819
Palld
Name: palladin, cytoskeletal associated protein
Synonyms: 2410003B16Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 72333
Homologene: 75052
Kat6a
Name: K(lysine) acetyltransferase 6A
Synonyms: MOZ, Zfp220, 9930021N24Rik, Myst3
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244349
Homologene: 4924
Pigo
Name: phosphatidylinositol glycan anchor biosynthesis, class O
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 56703
Homologene: 31761
C8b
Name: complement component 8, beta polypeptide
Synonyms: 4930439B20Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 110382
HGNC: HGNC:1353
Homologene: 48
Acad10
Name: acyl-Coenzyme A dehydrogenase family, member 10
Synonyms: 2410021P16Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 71985
Homologene: 49825
Gjb4
Name: gap junction protein, beta 4
Synonyms: Cx30.3, connexin 30.3, Gjb-4
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 14621
HGNC: HGNC:4286
Homologene: 7339
Col11a2
Name: collagen, type XI, alpha 2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 12815
HGNC: HGNC:2187
Homologene: 22547
Or8b101
Name: olfactory receptor family 8 subfamily B member 101
Synonyms: GA_x6K02T2PVTD-31787920-31788864, MOR162-4, Olfr888
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258416
Homologene: 84577
Sync
Name: syncoilin
Synonyms: SNIP4, 1110057H03Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 68828
Homologene: 11351
Rin2
Name: Ras and Rab interactor 2
Synonyms: RASSF4, 4632403N06Rik, 2010003K16Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 74030
Homologene: 32430
Capn3
Name: calpain 3
Synonyms: Capa-3, Capa3, Lp82, p94
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 12335
HGNC: HGNC:1480
Homologene: 52
A2ml1
Name: alpha-2-macroglobulin like 1
Synonyms: Ovos2, BC048546
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232400
Homologene: 45969
Fetub
Name: fetuin beta
Synonyms: 2310011O17Rik, D17980
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 59083
VEGA: 16
HGNC: HGNC:3658
Homologene: 8660
Or8b1b
Name: olfactory receptor family 8 subfamily B member 1B
Synonyms: GA_x6K02T2PVTD-32156773-32157705, MOR167-3, Olfr904
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258797
VEGA: 9
Homologene: 133629
Vmn2r74
Name: vomeronasal 2, receptor 74
Synonyms: EG546980
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 546980
Homologene: 115466
Pip5kl1
Name: phosphatidylinositol-4-phosphate 5-kinase-like 1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227733
Homologene: 45457
Sdk1
Name: sidekick cell adhesion molecule 1
Synonyms: 6720466O15Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 330222
Homologene: 27395
Abcc3
Name: ATP-binding cassette, sub-family C member 3
Synonyms: 1700019L09Rik, MRP3
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 76408
HGNC: HGNC:54
Homologene: 68364
Tas2r104
Name: taste receptor, type 2, member 104
Synonyms: Tas2r4, T2R04, mGR04, mt2r45
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 387340
Homologene: 130072
Plscr3
Name: phospholipid scramblase 3
Synonyms: 2610037N06Rik, 2210403O21Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 70310
Homologene: 23219
Ptprb
Name: protein tyrosine phosphatase receptor type B
Synonyms: 3230402H02Rik, VE-PTP
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 19263
VEGA: 10
HGNC: HGNC:9665
Homologene: 2125
Or8k30
Name: olfactory receptor family 8 subfamily K member 30
Synonyms: GA_x6K02T2Q125-47993761-47994702, MOR189-2, Olfr1076
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258401
Homologene: 17233
Tsga10
Name: testis specific 10
Synonyms: 4933432N21Rik, Mtsga10
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 211484
Homologene: 23531
Or2o1
Name: olfactory receptor family 2 subfamily O member 1
Synonyms: GA_x6K02T2QP88-6274566-6273628, MOR280-1, Olfr1394
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 258273
Homologene: 138305
Sorcs3
Name: sortilin-related VPS10 domain containing receptor 3
Synonyms: 6330404A12Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 66673
VEGA: 19
Homologene: 8986
Spata31f3
Name: spermatogenesis associated 31 subfamily F member 3
Synonyms: BC049635, Fam205c
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 277773
Homologene: 77625
Vmn1r189
Name: vomeronasal 1 receptor 189
Synonyms: V1rh2
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 252906
Homologene: 110880
Spata31e3
Name: spermatogenesis associated 31 subfamily E member 3
Synonyms: LOC380882, Gm906
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 380882
VEGA: 13
Homologene: 134512
Coq6
Name: coenzyme Q6 monooxygenase
Synonyms: 5930427M12Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217707
Homologene: 6039
Btbd6
Name: BTB domain containing 6
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 399566
VEGA: 12
Homologene: 41967
Cabyr
Name: calcium binding tyrosine phosphorylation regulated
Synonyms: FSP-2, CBP86, 4933421A18Rik, 1700016C01Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 71132
Homologene: 49299
Atp4b
Name: ATPase, H+/K+ exchanging, beta polypeptide
Synonyms: H+,K+-ATPase, H,K-ATPase-Beta, H+/K+-ATPase beta
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 11945
HGNC: HGNC:820
Homologene: 20182
Or8c17
Name: olfactory receptor family 8 subfamily C member 17
Synonyms: GA_x6K02T2PVTD-31962461-31963411, MOR170-1, Olfr895
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258875
Homologene: 74253
Slco1a7
Name: solute carrier organic anion transporter family, member 1a7
Synonyms: Gm5724
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 435927
Cd200r4
Name: CD200 receptor 4
Synonyms: MCD200RLa, F630107N04Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 239849
Homologene: 45557
Ndufaf1
Name: NADH:ubiquinone oxidoreductase complex assembly factor 1
Synonyms: CGI-65, CIA30, 2410001M24Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 69702
Homologene: 32289
Tas2r107
Name: taste receptor, type 2, member 107
Synonyms: T2R07, Tas2r7, T2R4, STC 5-1, mGR06, mt2r43
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 387342
Homologene: 137369
Vmn1r2
Name: vomeronasal 1 receptor 2
Synonyms: Gm11776
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 100312470
Homologene: 128342
Cflar
Name: CASP8 and FADD-like apoptosis regulator
Synonyms: Casper, A430105C05Rik, Flip, c-Flip, 2310024N18Rik, Cash
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12633
HGNC: HGNC:1876
Homologene: 7652
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 37,834,197 bp
  • A to C, chromosome 1 at 52,232,988 bp
  • T to A, chromosome 1 at 58,735,697 bp
  • A to T, chromosome 2 at 32,583,271 bp
  • T to C, chromosome 2 at 80,540,560 bp
  • T to G, chromosome 2 at 86,509,023 bp
  • C to T, chromosome 2 at 119,660,271 bp
  • T to C, chromosome 2 at 120,484,483 bp
  • T to C, chromosome 2 at 125,184,711 bp
  • A to G, chromosome 2 at 127,535,673 bp
  • C to T, chromosome 2 at 145,860,446 bp
  • G to A, chromosome 3 at 88,326,411 bp
  • A to T, chromosome 4 at 3,172,413 bp
  • A to T, chromosome 4 at 11,225,621 bp
  • A to G, chromosome 4 at 42,873,492 bp
  • A to T, chromosome 4 at 43,020,909 bp
  • G to T, chromosome 4 at 104,783,009 bp
  • G to A, chromosome 4 at 106,379,066 bp
  • A to G, chromosome 4 at 127,351,429 bp
  • T to C, chromosome 4 at 129,294,363 bp
  • A to T, chromosome 4 at 143,726,685 bp
  • T to A, chromosome 4 at 156,119,150 bp
  • A to G, chromosome 4 at 156,169,302 bp
  • A to G, chromosome 5 at 117,255,937 bp
  • A to T, chromosome 5 at 121,622,818 bp
  • A to G, chromosome 5 at 141,936,049 bp
  • T to C, chromosome 5 at 143,240,322 bp
  • T to A, chromosome 5 at 150,496,419 bp
  • A to G, chromosome 6 at 128,568,763 bp
  • A to C, chromosome 6 at 131,659,330 bp
  • T to A, chromosome 6 at 131,685,039 bp
  • T to C, chromosome 6 at 141,754,374 bp
  • A to G, chromosome 6 at 142,829,025 bp
  • T to G, chromosome 7 at 85,958,258 bp
  • T to A, chromosome 7 at 127,924,482 bp
  • T to C, chromosome 8 at 13,393,549 bp
  • G to T, chromosome 8 at 22,862,364 bp
  • T to C, chromosome 8 at 61,709,033 bp
  • A to T, chromosome 9 at 38,108,838 bp
  • T to G, chromosome 9 at 38,268,518 bp
  • T to A, chromosome 9 at 38,464,526 bp
  • T to C, chromosome 10 at 79,978,448 bp
  • A to T, chromosome 10 at 116,350,789 bp
  • A to G, chromosome 11 at 48,802,304 bp
  • A to G, chromosome 11 at 49,160,793 bp
  • A to G, chromosome 11 at 60,459,508 bp
  • G to A, chromosome 11 at 69,850,138 bp
  • T to A, chromosome 11 at 84,885,679 bp
  • T to C, chromosome 11 at 94,368,620 bp
  • A to G, chromosome 11 at 99,048,235 bp
  • A to G, chromosome 11 at 117,802,913 bp
  • T to C, chromosome 12 at 84,372,415 bp
  • A to G, chromosome 12 at 112,976,986 bp
  • T to A, chromosome 13 at 22,102,212 bp
  • T to A, chromosome 13 at 23,480,465 bp
  • G to A, chromosome 13 at 50,245,512 bp
  • T to C, chromosome 16 at 22,935,633 bp
  • T to C, chromosome 16 at 44,820,950 bp
  • T to C, chromosome 17 at 34,054,180 bp
  • T to C, chromosome 17 at 35,567,611 bp
  • A to G, chromosome 17 at 46,565,378 bp
  • A to G, chromosome 17 at 66,809,575 bp
  • T to C, chromosome 18 at 6,061,930 bp
  • T to A, chromosome 18 at 12,751,690 bp
  • C to T, chromosome 18 at 74,661,655 bp
  • T to A, chromosome 19 at 48,722,956 bp
  • G to A, chromosome 19 at 55,283,399 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3824 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
040885-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.