Strain Name:
C57BL/6J-MtgxR3828Btlr/Mmmh
Stock Number:
040886-MU
Citation ID:
RRID:MMRRC_040886-MU
Other Names:
R3828 (G1), C57BL/6J-MtgxR3828Btlr
Major Collection:

Gene Information

Cdk19
Name: cyclin-dependent kinase 19
Synonyms: 2700084L06Rik, Cdc2l6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 78334
VEGA: 10
Homologene: 22862
Tmem59l
Name: transmembrane protein 59-like
Synonyms: 5330410G16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 67937
Homologene: 8104
Lrp2
Name: low density lipoprotein receptor-related protein 2
Synonyms: b2b1625.2Clo, D230004K18Rik, Megalin, Gp330
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14725
HGNC: HGNC:6694
Homologene: 20952
Prkdc
Name: protein kinase, DNA activated, catalytic polypeptide
Synonyms: dxnph, slip, DOXNPH, DNA-PK, DNA-PKcs, XRCC7, DNAPDcs
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 19090
HGNC: HGNC:9413
Homologene: 5037
Tnks
Name: tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
Synonyms: TANK1, 4930554K12Rik, mTNKS1, tankyrase 1, D130072O21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 21951
Homologene: 18405
Cep104
Name: centrosomal protein 104
Synonyms: BC046331
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230967
Homologene: 44919
Usp15
Name: ubiquitin specific peptidase 15
Synonyms: Gcap18, 4921514G19Rik, E430033I05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 14479
VEGA: 10
Homologene: 101542
Ncapg2
Name: non-SMC condensin II complex, subunit G2
Synonyms: 5830426I05Rik, mCAP-G2, Mtb, Luzp5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 76044
VEGA: 12
Homologene: 9820
Gpat4
Name: glycerol-3-phosphate acyltransferase 4
Synonyms: Agpat6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 102247
Homologene: 32425
4932438A13Rik
Name: RIKEN cDNA 4932438A13 gene
Synonyms: FSA, Tweek
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229227
Homologene: 52105
Mark4
Name: MAP/microtubule affinity regulating kinase 4
Synonyms: 2410090P21Rik, Markl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 232944
Homologene: 57146
Commd9
Name: COMM domain containing 9
Synonyms: 1810029F08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 76501
Homologene: 8584
Vps50
Name: VPS50 EARP/GARPII complex subunit
Synonyms: Ccdc132, 1700034M03Rik, 8430415E05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 73288
Homologene: 11498
Chd2
Name: chromodomain helicase DNA binding protein 2
Synonyms: 5630401D06Rik, 2810013C04Rik, 2810040A01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 244059
HGNC: HGNC:1917
Homologene: 37462
Ino80d
Name: INO80 complex subunit D
Synonyms: A430093A21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227195
Homologene: 9819
Syt14
Name: synaptotagmin XIV
Synonyms: B230320I09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 329324
Homologene: 17719
Mcm9
Name: minichromosome maintenance 9 homologous recombination repair factor
Synonyms: Mcmdc1, 9030408O17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 71567
VEGA: 10
Homologene: 13546
Stk11
Name: serine/threonine kinase 11
Synonyms: Lkb1, Par-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 20869
Homologene: 393
Mcoln1
Name: mucolipin 1
Synonyms: 2210015I05Rik, TRPML1, mucolipidin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 94178
Homologene: 10744
Slc9c1
Name: solute carrier family 9, subfamily C (Na+-transporting carboxylic acid decarboxylase), member 1
Synonyms: LOC208169, Slc9a10, spermNHE
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 208169
Homologene: 19505
Dnah17
Name: dynein, axonemal, heavy chain 17
Synonyms: Dnahcl1, Dnahc17, LOC382552, 2810003K23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 69926
HGNC: HGNC:2946
Homologene: 72102
Gm17521
Name: predicted gene, 17521
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
Col4a1
Name: collagen, type IV, alpha 1
Synonyms: alpha1(IV) collagen, Col4a-1, Del(8)Bru44H, Del(8)44H, Raw, Svc, Bru
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 12826
HGNC: HGNC:2202
Homologene: 20437
Olfr679
Name: olfactory receptor 679
Synonyms: MOR40-2, GA_x6K02T2PBJ9-7714499-7715446
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259046
Homologene: 81538
Dlg5
Name: discs large MAGUK scaffold protein 5
Synonyms: 4933429D20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 71228
HGNC: HGNC:2904
Homologene: 3486
Cbr2
Name: carbonyl reductase 2
Synonyms: MLCR, lung carbonyl reductase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 12409
Homologene: 104184
Rsph6a
Name: radial spoke head 6 homolog A (Chlamydomonas)
Synonyms: RSP4, Rshl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 83434
Homologene: 36476
Cxcr6
Name: chemokine (C-X-C motif) receptor 6
Synonyms: STRL33, BONZO
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 80901
VEGA: 9
Homologene: 38197
Cplane2
Name: ciliogenesis and planar polarity effector 2
Synonyms: 6330545A04Rik, b2b2804Clo, LOC279260, Rsg1, b2b2827Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 76166
Homologene: 12793
Mrgprb5
Name: MAS-related GPR, member B5
Synonyms: MrgB5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 404239
Homologene: 115575
Zdhhc19
Name: zinc finger, DHHC domain containing 19
Synonyms: LOC245308
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 245308
Homologene: 34922
Rtkn2
Name: rhotekin 2
Synonyms: Plekhk1, B130039D23Rik, RTKN2, Mbf
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 170799
Homologene: 17065
Camk2b
Name: calcium/calmodulin-dependent protein kinase II, beta
Synonyms: CaMK II
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 12323
HGNC: HGNC:1461
Homologene: 111050
Cx3cl1
Name: chemokine (C-X3-C motif) ligand 1
Synonyms: neurotactin, fractalkine, CX3C, D8Bwg0439e, Scyd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 20312
Homologene: 2251
Rrm2
Name: ribonucleotide reductase M2
Synonyms: R2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 20135
Homologene: 20277
Ffar2
Name: free fatty acid receptor 2
Synonyms: Gpr43
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233079
HGNC: HGNC:4501
Homologene: 133911
Gm5862
Name: predicted gene 5862
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 545739
Homologene: 69402
Mcts1
Name: malignant T cell amplified sequence 1
Synonyms: MCT-1, 1500019M23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 68995
Homologene: 5803
Fam199x
Name: family with sequence similarity 199, X-linked
Synonyms: BC031748
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 245622
Homologene: 17156
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 63,062,078 bp
  • T to C, chromosome 1 at 192,901,775 bp
  • G to A, chromosome 2 at 69,426,012 bp
  • C to A, chromosome 2 at 101,897,141 bp
  • A to G, chromosome 3 at 37,004,825 bp
  • C to T, chromosome 4 at 141,218,589 bp
  • T to G, chromosome 4 at 153,984,943 bp
  • T to G, chromosome 5 at 26,019,347 bp
  • T to C, chromosome 6 at 3,533,500 bp
  • T to C, chromosome 7 at 19,057,614 bp
  • A to G, chromosome 7 at 19,443,187 bp
  • A to T, chromosome 7 at 30,820,085 bp
  • T to A, chromosome 7 at 48,168,091 bp
  • A to G, chromosome 7 at 73,491,415 bp
  • A to G, chromosome 7 at 105,086,297 bp
  • C to T, chromosome 8 at 3,500,601 bp
  • C to A, chromosome 8 at 11,209,650 bp
  • G to A, chromosome 8 at 23,180,155 bp
  • A to G, chromosome 8 at 34,873,178 bp
  • A to G, chromosome 8 at 70,487,301 bp
  • A to T, chromosome 8 at 94,777,306 bp
  • A to T, chromosome 9 at 123,810,869 bp
  • T to C, chromosome 10 at 40,475,613 bp
  • C to A, chromosome 10 at 53,630,141 bp
  • A to T, chromosome 10 at 67,997,626 bp
  • T to C, chromosome 10 at 80,127,948 bp
  • T to A, chromosome 10 at 123,196,870 bp
  • A to G, chromosome 11 at 6,028,932 bp
  • G to A, chromosome 11 at 118,041,158 bp
  • A to T, chromosome 11 at 120,730,452 bp
  • G to T, chromosome 12 at 24,708,599 bp
  • A to T, chromosome 12 at 116,407,318 bp
  • T to A, chromosome 14 at 24,146,158 bp
  • A to G, chromosome 16 at 15,835,251 bp
  • T to C, chromosome 16 at 32,507,031 bp
  • T to C, chromosome 16 at 45,601,863 bp
  • T to C, chromosome X at 38,602,568 bp
  • C to A, chromosome X at 123,029,225 bp
  • T to C, chromosome X at 137,072,186 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3828 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040886-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.