Strain Name:
C57BL/6J-MtgxR3855Btlr/Mmmh
Stock Number:
040901-MU
Citation ID:
RRID:MMRRC_040901-MU
Other Names:
R3855 (G1), C57BL/6J-MtgxR3855Btlr
Major Collection:

Gene Information

Ntrk2
Name: neurotrophic tyrosine kinase, receptor, type 2
Synonyms: trkB, C030027L06Rik, Tkrb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 18212
VEGA: 13
HGNC: HGNC:8032
Homologene: 4504
Lmf1
Name: lipase maturation factor 1
Synonyms: Tmem112, 2400010G15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 76483
Homologene: 23384
Nfia
Name: nuclear factor I/A
Synonyms: NF1A, 9430022M17Rik, NF1-A, 1110047K16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 18027
HGNC: HGNC:7784
Homologene: 4086
Rnf145
Name: ring finger protein 145
Synonyms: 3732413I11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 74315
Homologene: 14427
Sgsm1
Name: small G protein signaling modulator 1
Synonyms: Rutbc2, D5Bwg1524e, 2410098H20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 52850
Homologene: 64485
Kmt2a
Name: lysine (K)-specific methyltransferase 2A
Synonyms: HTRX1, Mll1, Cxxc7, All1, ALL-1, trithorax Drosophila, Mll
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 214162
HGNC: HGNC:7132
Homologene: 4338
Nufip2
Name: nuclear fragile X mental retardation protein interacting protein 2
Synonyms: 1110001M19Rik, 9530056D24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 68564
Homologene: 10808
Dennd4c
Name: DENN/MADD domain containing 4C
Synonyms: 1700065A05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 329877
Homologene: 23057
Vps26c
Name: VPS26 endosomal protein sorting factor C
Synonyms: Down syndrome critical region gene 3, Dscr3, Dcra
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 13185
HGNC: HGNC:3044
Homologene: 4415
Zfp512
Name: zinc finger protein 512
Synonyms: 2500002M11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 269639
Homologene: 13026
Hk2
Name: hexokinase 2
Synonyms: HKII
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 15277
HGNC: HGNC:4923
Homologene: 37273
Mdh1
Name: malate dehydrogenase 1, NAD (soluble)
Synonyms: B230377B03Rik, MDH-s, Mor2, Mor-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 17449
HGNC: HGNC:6970
Homologene: 4324
Sox11
Name: SRY (sex determining region Y)-box 11
Synonyms: 1110038H03Rik, 6230403H02Rik, end1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 20666
Homologene: 37733
Arhgef1
Name: Rho guanine nucleotide exchange factor (GEF) 1
Synonyms: Lsc, Lbcl2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 16801
HGNC: HGNC:681
Homologene: 3454
Itgb3bp
Name: integrin beta 3 binding protein (beta3-endonexin)
Synonyms: 4930471O16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 67733
HGNC: HGNC:6157
Homologene: 8617
Apex1
Name: apurinic/apyrimidinic endonuclease 1
Synonyms: Ref-1, HAP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 11792
HGNC: HGNC:587
Homologene: 1241
Nhlrc2
Name: NHL repeat containing 2
Synonyms: 1200003G01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 66866
VEGA: 19
Homologene: 12048
Usp54
Name: ubiquitin specific peptidase 54
Synonyms: C030002J06Rik, 4930429G18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 78787
Homologene: 90902
Prmt9
Name: protein arginine methyltransferase 9
Synonyms: Prmt10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 102182
Homologene: 16298
Pkd1l1
Name: polycystic kidney disease 1 like 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 171395
Homologene: 51376
Nbas
Name: neuroblastoma amplified sequence
Synonyms: 4933425L03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 71169
VEGA: 12
Homologene: 41073
Atp1a3
Name: ATPase, Na+/K+ transporting, alpha 3 polypeptide
Synonyms: Atpa-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 232975
HGNC: HGNC:801
Homologene: 113729
Kmt5c
Name: lysine methyltransferase 5C
Synonyms: Suv4-20h2, Suv420h2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 232811
Homologene: 32792
Kif17
Name: kinesin family member 17
Synonyms: N-4 kinesin, 5930435E01Rik, Kif17b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 16559
Homologene: 5883
Ppfia2
Name: protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
Synonyms: Liprin-alpha2, E130120L08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 327814
VEGA: 10
HGNC: HGNC:9246
Homologene: 27953
Xylt1
Name: xylosyltransferase 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233781
Homologene: 32534
Otog
Name: otogelin
Synonyms: Otgn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 18419
HGNC: HGNC:8516
Homologene: 8421
Akna
Name: AT-hook transcription factor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100182
Homologene: 49947
Pear1
Name: platelet endothelial aggregation receptor 1
Synonyms: 3110045G13Rik, Jedi-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 73182
Homologene: 12492
Gpr179
Name: G protein-coupled receptor 179
Synonyms: 5330439C02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217143
Homologene: 34917
Prg4
Name: proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)
Synonyms: DOL54, MSF, lubricin, SZP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 96875
HGNC: HGNC:9364
Homologene: 137352
Cog2
Name: component of oligomeric golgi complex 2
Synonyms: Cog2, 1190002B08Rik, 2700012E02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 76332
HGNC: HGNC:6546
Homologene: 7206
Grik5
Name: glutamate receptor, ionotropic, kainate 5 (gamma 2)
Synonyms: GluRgamma2, KA2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 14809
HGNC: HGNC:4583
Homologene: 1578
Dthd1
Name: death domain containing 1
Synonyms: Gm17384
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100322896
Homologene: 123510
Pla2g4a
Name: phospholipase A2, group IVA (cytosolic, calcium-dependent)
Synonyms: cPLA2, Type IV PLA2, cytosolic PLA2, cPLA2alpha, Pla2g4, cytosolic phospholipase A2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 18783
HGNC: HGNC:9035
Homologene: 32059
Olfr1380
Name: olfactory receptor 1380
Synonyms: GA_x6K02T2QP88-5871967-5871032, MOR256-66_i
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 404336
Homologene: 72463
Idi1
Name: isopentenyl-diphosphate delta isomerase
Synonyms: 4832416K17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 319554
HGNC: HGNC:5387
Homologene: 3315
Ppig
Name: peptidyl-prolyl isomerase G (cyclophilin G)
Synonyms: SRCyp, B230312B02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228005
Homologene: 3520
Apbb1ip
Name: amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
Synonyms: 9930118P07Rik, proline-rich protein 48, Prp48
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 54519
Homologene: 32434
Sv2c
Name: synaptic vesicle glycoprotein 2c
Synonyms: 4930527L09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 75209
Homologene: 57152
Galnt7
Name: polypeptide N-acetylgalactosaminyltransferase 7
Synonyms: ppGaNTase-T7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 108150
HGNC: HGNC:4129
Homologene: 9685
Nt5c2
Name: 5'-nucleotidase, cytosolic II
Synonyms: cN-II, NT5B, PNT5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 76952
HGNC: HGNC:8022
Homologene: 8158
Olfr364-ps1
Name: olfactory receptor 364, pseudogene 1
Synonyms: MOR138-4P, MOR138-7, GA_x6K02T2NLDC-33831282-33832243
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227794
HGNC: HGNC:8216
Gm4868
Name: predicted gene 4868
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231736
Homologene: 138658
Sepsecs
Name: Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
Synonyms: D5Ertd135e, SecS, SLA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 211006
Homologene: 15031
Nme5
Name: NME/NM23 family member 5
Synonyms: Nm23-M5, non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase), 1700019D05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 75533
HGNC: HGNC:7853
Homologene: 2628
Khk
Name: ketohexokinase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 16548
HGNC: HGNC:6315
Homologene: 38187
Ccnq
Name: cyclin Q
Synonyms: 1810009O10Rik, Fam58b, cyclin M
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 69109
Homologene: 13362
Fxyd1
Name: FXYD domain-containing ion transport regulator 1
Synonyms: PLM, 0610012C17Rik, 1110006M24Rik, phospholemman, PML
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 56188
HGNC: HGNC:4025
Homologene: 3691
Ggnbp1
Name: gametogenetin binding protein 1
Synonyms: 0610031G08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 70772
Homologene: 79568
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 149,830,177 bp
  • T to C, chromosome 1 at 150,452,000 bp
  • T to C, chromosome 2 at 22,875,175 bp
  • A to T, chromosome 2 at 37,146,823 bp
  • G to A, chromosome 2 at 69,749,375 bp
  • T to C, chromosome 3 at 87,751,921 bp
  • A to T, chromosome 4 at 63,373,468 bp
  • G to A, chromosome 4 at 86,779,847 bp
  • A to G, chromosome 4 at 98,063,022 bp
  • T to C, chromosome 4 at 99,798,720 bp
  • A to G, chromosome 4 at 138,291,510 bp
  • A to G, chromosome 5 at 30,927,057 bp
  • A to G, chromosome 5 at 31,480,249 bp
  • G to A, chromosome 5 at 52,664,274 bp
  • T to A, chromosome 5 at 62,827,129 bp
  • T to C, chromosome 5 at 62,888,023 bp
  • A to G, chromosome 5 at 113,263,259 bp
  • A to G, chromosome 5 at 125,848,545 bp
  • T to C, chromosome 6 at 82,736,676 bp
  • T to C, chromosome 7 at 4,746,256 bp
  • G to A, chromosome 7 at 24,919,272 bp
  • A to G, chromosome 7 at 24,989,979 bp
  • A to C, chromosome 7 at 25,015,539 bp
  • G to A, chromosome 7 at 31,053,878 bp
  • T to C, chromosome 7 at 46,273,760 bp
  • T to G, chromosome 7 at 117,593,550 bp
  • T to C, chromosome 8 at 57,532,624 bp
  • G to A, chromosome 8 at 77,568,265 bp
  • T to C, chromosome 8 at 124,530,003 bp
  • A to G, chromosome 9 at 44,830,499 bp
  • G to A, chromosome 10 at 106,858,411 bp
  • A to G, chromosome 11 at 8,965,047 bp
  • C to T, chromosome 11 at 21,559,281 bp
  • G to A, chromosome 11 at 44,531,293 bp
  • A to G, chromosome 11 at 49,564,091 bp
  • T to C, chromosome 11 at 77,692,889 bp
  • T to C, chromosome 11 at 78,751,187 bp
  • T to C, chromosome 11 at 97,341,434 bp
  • T to A, chromosome 12 at 13,279,414 bp
  • C to A, chromosome 12 at 27,341,502 bp
  • G to T, chromosome 13 at 8,885,932 bp
  • T to A, chromosome 13 at 58,871,782 bp
  • T to C, chromosome 13 at 96,030,474 bp
  • C to A, chromosome 14 at 20,588,420 bp
  • A to G, chromosome 14 at 50,926,257 bp
  • A to G, chromosome 16 at 94,510,806 bp
  • G to A, chromosome 17 at 25,654,471 bp
  • T to C, chromosome 17 at 27,032,548 bp
  • A to G, chromosome 18 at 34,569,831 bp
  • A to G, chromosome 19 at 46,896,518 bp
  • T to C, chromosome 19 at 56,588,271 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3855 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040901-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.