Strain Name:
C57BL/6J-MtgxR3911Btlr/Mmmh
Stock Number:
040909-MU
Citation ID:
RRID:MMRRC_040909-MU
Other Names:
R3911 (G1), C57BL/6J-MtgxR3911Btlr
Major Collection:

Strain Information

Strap
Name: serine/threonine kinase receptor associated protein
Synonyms: Unrip, C78091
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 20901
Homologene: 43881
Cnnm2
Name: cyclin M2
Synonyms: Acdp2
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 94219
VEGA: 19
HGNC: HGNC:103
Homologene: 9761
Pank4
Name: pantothenate kinase 4
Synonyms: D030031I12Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 269614
Homologene: 41235
Itgb8
Name: integrin beta 8
Synonyms: 4832412O06Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 320910
HGNC: HGNC:6163
Homologene: 18567
Fasl
Name: Fas ligand
Synonyms: CD178, Tnfsf6, Fas-L, APT1LG1, Fasl, CD95L
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 14103
Homologene: 533
Adgre1
Name: adhesion G protein-coupled receptor E1
Synonyms: EGF-TM7, Ly71, F4/80, Emr1, TM7LN3, DD7A5-7
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 13733
VEGA: 17
HGNC: HGNC:3336
Homologene: 1493
Casp8
Name: caspase 8
Synonyms: MACH, FLICE, Caspase-8, Mch5
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12370
HGNC: HGNC:1509
Homologene: 7657
Epha7
Name: Eph receptor A7
Synonyms: MDK1, Hek11, Mdk1, Cek11, Ebk, Ehk3
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 13841
HGNC: HGNC:3390
Homologene: 20935
Cd2ap
Name: CD2-associated protein
Synonyms: METS-1, Mets1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 12488
VEGA: 17
Homologene: 7663
Pds5b
Name: PDS5 cohesin associated factor B
Synonyms: Aprin, AS3
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100710
Homologene: 41001
Map1b
Name: microtubule-associated protein 1B
Synonyms: Mtap1b, Mtap5, LC1, MAP5, Mtap-5
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 17755
VEGA: 13
HGNC: HGNC:6836
Homologene: 38111
Tmem63b
Name: transmembrane protein 63b
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224807
Homologene: 101682
Vps35l
Name: VPS35 endosomal protein sorting factor like
Synonyms: Vsp35l, 9030624J02Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 71517
Homologene: 10659
Aebp2
Name: AE binding protein 2
Synonyms: B230313N05Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 11569
Homologene: 40690
Sf3b1
Name: splicing factor 3b, subunit 1
Synonyms: Targ4, SAP155, 2810001M05Rik, SF3b155, Prp10
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 81898
Homologene: 6696
Kat14
Name: lysine acetyltransferase 14
Synonyms: D2Wsu131e, Csrp2bp, 2510008M08Rik, ATAC2, D2Ertd473e
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228714
Homologene: 10745
Sh3d19
Name: SH3 domain protein D19
Synonyms: Kryn
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 27059
Homologene: 19064
Pou4f1
Name: POU domain, class 4, transcription factor 1
Synonyms: Brn-3, E130119J07Rik, Brn3, Brn-3.0, Brn3a
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 18996
HGNC: HGNC:9218
Homologene: 21255
Mcm2
Name: minichromosome maintenance complex component 2
Synonyms: Mcmd2, BM28, CDCL1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 17216
HGNC: HGNC:6944
Homologene: 3325
Rlim
Name: ring finger protein, LIM domain interacting
Synonyms: Rnf12, Rlim1, Ha1r
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 19820
Homologene: 7920
Bod1l
Name: biorientation of chromosomes in cell division 1-like
Synonyms: A230054D04Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 665775
Homologene: 45109
Tmtc3
Name: transmembrane and tetratricopeptide repeat containing 3
Synonyms: mSmile, 9130014E20Rik, B130008E12Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 237500
Homologene: 27616
Gab2
Name: growth factor receptor bound protein 2-associated protein 2
Synonyms: p97, D130058I17Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 14389
Homologene: 69067
Fcrl2
Name: Fc receptor like 2
Synonyms: Fcrls, 2810439C17Rik, IFGP2, Msr2, Fcrh2, moFcRH2sc
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 80891
Homologene: 57117
Hepacam2
Name: HEPACAM family member 2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 101202
Homologene: 18724
Tcf7
Name: transcription factor 7, T cell specific
Synonyms: Tcf1, TCF-1, T cell factor-1, T-cell factor 1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 21414
Homologene: 137220
Cntrl
Name: centriolin
Synonyms: Cep110, b2b1468Clo, IB3/5, Ma2a8, 6720467O09Rik, Cep1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 26920
HGNC: HGNC:1858
Homologene: 38260
Kirrel1
Name: kirre like nephrin family adhesion molecule 1
Synonyms: Kirrel, Kirrel1, 6720469N11Rik, Neph1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 170643
Homologene: 10089
Asap3
Name: ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
Synonyms: UPLC1, Ddefl1, 9430088F20Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230837
Homologene: 41190
Tns2
Name: tensin 2
Synonyms: nep, nph, Tenc1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 209039
VEGA: 15
Homologene: 37077
Tnfrsf11b
Name: tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)
Synonyms: OPG, Opg, osteoclastogenesis inhibitory factor, OCIF, TR1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 18383
VEGA: 15
Homologene: 1912
Ush2a
Name: usherin
Synonyms: MUSH2A, LOC269160, Ush2a, A930037M10Rik, A930011D15Rik, LOC381317, Ushrn
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 22283
Homologene: 66151
Dnah17
Name: dynein, axonemal, heavy chain 17
Synonyms: LOC382552, Dnahcl1, Dnahc17, 2810003K23Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 69926
HGNC: HGNC:2946
Homologene: 72102
Gm17067
Name: predicted gene 17067
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 115486519
Gpld1
Name: glycosylphosphatidylinositol specific phospholipase D1
Synonyms: 6330541J12Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 14756
HGNC: HGNC:4459
Homologene: 1152
Megf10
Name: multiple EGF-like-domains 10
Synonyms: 3000002B06Rik, LOC240312
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 70417
Homologene: 23771
Abcc12
Name: ATP-binding cassette, sub-family C member 12
Synonyms: 4930467B22Rik, MRP9
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244562
Homologene: 57211
Dhrs11
Name: dehydrogenase/reductase 11
Synonyms: dehydrogenase/reductase (SDR family) member 11
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 192970
Homologene: 41560
Abcb9
Name: ATP-binding cassette, sub-family B member 9
Synonyms: TAPL
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 56325
HGNC: HGNC:50
Homologene: 10491
Flg
Name: filaggrin
Synonyms: ft, fillagrin, profilaggrin
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 14246
VEGA: 3
Trim30a
Name: tripartite motif-containing 30A
Synonyms: Trim30, Rpt-1, Rpt1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 20128
Homologene: 114426
Npr2
Name: natriuretic peptide receptor 2
Synonyms: cn, guanylyl cyclase-B, pwe
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230103
HGNC: HGNC:7944
Homologene: 2970
Krtap4-8
Name: keratin associated protein 4-8
Synonyms: OTTMUSG00000002541
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 665992
Or51ai2
Name: olfactory receptor family 51 subfamily AI member 2
Synonyms: Olfr632, GA_x6K02T2PBJ9-6671256-6672209, MOR2-1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 259123
Homologene: 64963
Gucy1a2
Name: guanylate cyclase 1, soluble, alpha 2
Synonyms: A230060L24Rik, 6330407I18Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 234889
HGNC: HGNC:4684
Homologene: 47953
Proc
Name: protein C
Synonyms: PC, inactivator of coagulation factors Va, VIII
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 19123
VEGA: 18
HGNC: HGNC:9451
Homologene: 37288
Cyp2b23
Name: cytochrome P450, family 2, subfamily b, polypeptide 23
Synonyms: EG243881
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 243881
HGNC: HGNC:2615
Homologene: 117483
Mcpt9
Name: mast cell protease 9
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 17232
VEGA: 14
Homologene: 115745
Vmn2r99
Name: vomeronasal 2, receptor 99
Synonyms: EG665376
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 665376
Homologene: 115024
Serpinb6c
Name: serine (or cysteine) peptidase inhibitor, clade B, member 6c
Synonyms: Spi3C, ovalbumin, SPIC
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 97848
HGNC: HGNC:8950
Ptk2b
Name: PTK2 protein tyrosine kinase 2 beta
Synonyms: Raftk, CAKbeta, cellular adhesion kinase beta, proline-rich tyrosine kinase 2, related adhesion focal tyrosine kinase, E430023O05Rik, PYK2, calcium-dependent tyrosine kinase
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 19229
HGNC: HGNC:9612
Homologene: 23001
Krt90
Name: keratin 90
Synonyms: 4732456N10Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 239673
Homologene: 72272
Clip1
Name: CAP-GLY domain containing linker protein 1
Synonyms: Clip 170, Clip50, CLIP-170, 4631429H07Rik, cytoplasmic linker protein 50, Rsn, restin, 1110007I12Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 56430
Homologene: 74455
Edc3
Name: enhancer of mRNA decapping 3
Synonyms: Yjdc, Lsm16
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 353190
Homologene: 11827
Fnip2
Name: folliculin interacting protein 2
Synonyms: D630023B12Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 329679
Homologene: 46417
Iqca1l
Name: IQ motif containing with AAA domain 1 like
Synonyms: 4931409K22Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231045
Homologene: 18602
Wdr35
Name: WD repeat domain 35
Synonyms: 4930459M12Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 74682
Homologene: 10814
Pfkm
Name: phosphofructokinase, muscle
Synonyms: Pfkx, PFK-A, Pfk4, PFK-M, Pfk-4
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 18642
VEGA: 15
HGNC: HGNC:8877
Homologene: 20101
Klhl18
Name: kelch-like 18
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 270201
Homologene: 14805
Ovch2
Name: ovochymase 2
Synonyms: 9230106D23Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 244199
Homologene: 18255
Spata1
Name: spermatogenesis associated 1
Synonyms: SP-2, 4921536I21Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 70951
Homologene: 23356
Tpi1
Name: triosephosphate isomerase 1
Synonyms: Tpi-1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 21991
Homologene: 128432
Slc30a8
Name: solute carrier family 30 (zinc transporter), member 8
Synonyms: C820002P14Rik, ZnT-8, ZnT8
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 239436
Homologene: 13795
Phc2
Name: polyhomeotic 2
Synonyms: Edr2, D130050K19Rik, Mph2, D4Ertd810e
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 54383
HGNC: HGNC:3183
Homologene: 75090
Or2ag18
Name: olfactory receptor family 2 subfamily AG member 18
Synonyms: MOR283-4, GA_x6K02T2PBJ9-9184187-9183237, Olfr700
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258593
Homologene: 64895
Wnt10b
Name: wingless-type MMTV integration site family, member 10B
Synonyms: Wnt12
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 22410
VEGA: 15
Homologene: 20721
Cchcr1
Name: coiled-coil alpha-helical rod protein 1
Synonyms: Hcr
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 240084
Homologene: 10396
Lsp1
Name: lymphocyte specific 1
Synonyms: Lsp-1, lymphocyte-specific protein 1, leukocyte-specific protein 1, p50, pp52, leukocyte specific protein 1, WP34
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 16985
HGNC: HGNC:6707
Homologene: 1750
Tmem114
Name: transmembrane protein 114
Synonyms: 4930511J11Rik, Cldn26
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 74720
VEGA: 16
Homologene: 12583
Cimip3
Name: ciliary microtubule inner protein 3
Synonyms: 1700001C19Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 75462
Homologene: 129540
Gpr137c
Name: G protein-coupled receptor 137C
Synonyms: LOC380893, TM7SF1L2, 6330416L11Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 70713
Homologene: 28613
Cdk5rap1
Name: CDK5 regulatory subunit associated protein 1
Synonyms: 2310066P17Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 66971
Homologene: 9502
Kcnj15
Name: potassium inwardly-rectifying channel, subfamily J, member 15
Synonyms: Kir4.2, IRKK, 4930414N08Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 16516
HGNC: HGNC:6261
Homologene: 1690
Emg1
Name: EMG1 N1-specific pseudouridine methyltransferase
Synonyms: Grcc2f
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 14791
Homologene: 4617
AC090887.5
Name:
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to A, chromosome 1 at 55,019,389 bp
  • A to T, chromosome 1 at 58,833,705 bp
  • C to A, chromosome 1 at 161,788,191 bp
  • T to A, chromosome 1 at 188,399,954 bp
  • G to A, chromosome 2 at 35,120,049 bp
  • T to C, chromosome 2 at 144,404,062 bp
  • A to G, chromosome 2 at 154,345,854 bp
  • A to T, chromosome 3 at 79,479,505 bp
  • G to A, chromosome 3 at 86,107,227 bp
  • C to T, chromosome 3 at 87,089,151 bp
  • A to T, chromosome 3 at 87,259,351 bp
  • A to T, chromosome 3 at 93,280,000 bp
  • T to A, chromosome 3 at 146,475,324 bp
  • G to A, chromosome 4 at 28,938,680 bp
  • C to T, chromosome 4 at 43,633,745 bp
  • T to C, chromosome 4 at 128,743,558 bp
  • A to G, chromosome 4 at 136,229,457 bp
  • A to G, chromosome 4 at 154,969,601 bp
  • A to T, chromosome 5 at 24,545,442 bp
  • T to C, chromosome 5 at 41,817,098 bp
  • T to A, chromosome 5 at 123,590,834 bp
  • T to A, chromosome 5 at 124,089,846 bp
  • T to A, chromosome 5 at 150,746,706 bp
  • A to G, chromosome 6 at 3,494,477 bp
  • A to G, chromosome 6 at 88,888,252 bp
  • T to A, chromosome 6 at 124,705,046 bp
  • A to T, chromosome 6 at 124,812,923 bp
  • T to G, chromosome 6 at 137,735,382 bp
  • T to A, chromosome 6 at 140,647,981 bp
  • A to T, chromosome 7 at 26,681,417 bp
  • T to A, chromosome 7 at 42,710,680 bp
  • A to G, chromosome 7 at 97,299,073 bp
  • A to T, chromosome 7 at 103,937,409 bp
  • A to G, chromosome 7 at 104,411,141 bp
  • A to T, chromosome 7 at 106,805,865 bp
  • T to A, chromosome 7 at 107,788,590 bp
  • A to G, chromosome 7 at 118,746,390 bp
  • C to T, chromosome 7 at 142,486,361 bp
  • A to C, chromosome 8 at 86,528,419 bp
  • T to C, chromosome 9 at 3,894,489 bp
  • A to T, chromosome 9 at 57,748,403 bp
  • A to T, chromosome 9 at 110,436,083 bp
  • A to C, chromosome 10 at 100,449,026 bp
  • C to A, chromosome 11 at 52,282,966 bp
  • A to T, chromosome 11 at 84,821,753 bp
  • A to T, chromosome 11 at 99,780,037 bp
  • C to T, chromosome 11 at 118,080,849 bp
  • A to T, chromosome 12 at 8,986,077 bp
  • A to T, chromosome 12 at 113,597,440 bp
  • T to A, chromosome 12 at 119,168,005 bp
  • A to G, chromosome 13 at 24,962,322 bp
  • T to C, chromosome 13 at 33,893,905 bp
  • A to G, chromosome 13 at 99,431,072 bp
  • C to A, chromosome 14 at 45,278,935 bp
  • T to C, chromosome 14 at 56,027,679 bp
  • C to T, chromosome 14 at 66,157,068 bp
  • C to T, chromosome 14 at 104,466,175 bp
  • A to G, chromosome 15 at 52,321,701 bp
  • G to A, chromosome 15 at 54,256,182 bp
  • A to G, chromosome 15 at 98,125,047 bp
  • G to T, chromosome 15 at 98,774,338 bp
  • G to A, chromosome 15 at 101,562,783 bp
  • T to C, chromosome 15 at 102,113,837 bp
  • A to T, chromosome 16 at 8,412,190 bp
  • C to T, chromosome 16 at 95,296,470 bp
  • T to C, chromosome 17 at 19,394,373 bp
  • T to C, chromosome 17 at 35,525,336 bp
  • T to A, chromosome 17 at 42,816,089 bp
  • A to G, chromosome 17 at 45,677,958 bp
  • AC to A, chromosome 17 at 47,433,423 bp
  • G to T, chromosome 17 at 57,447,860 bp
  • A to G, chromosome 18 at 32,123,705 bp
  • A to T, chromosome 18 at 57,289,393 bp
  • A to G, chromosome 19 at 46,877,936 bp
  • T to C, chromosome X at 103,962,661 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3911 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
040909-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.