Strain Name:
C57BL/6J-MtgxR3930Btlr/Mmmh
Stock Number:
040917-MU
Citation ID:
RRID:MMRRC_040917-MU
Other Names:
R3930 (G1), C57BL/6J-MtgxR3930Btlr
Major Collection:

Gene Information

Sez6
Name: seizure related gene 6
Synonyms: sez-6, D11Bhm177e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20370
Homologene: 10948
Crhr1
Name: corticotropin releasing hormone receptor 1
Synonyms: CRFR1, CRF-R1alpha, CRF 1 receptor, CRF1R
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 12921
HGNC: HGNC:2357
Homologene: 20920
Gpr37l1
Name: G protein-coupled receptor 37-like 1
Synonyms: CAG-18, D0Kist8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 171469
Homologene: 3500
Map3k4
Name: mitogen-activated protein kinase kinase kinase 4
Synonyms: MTK1, MAPKKK4, D17Rp17, RP17, D17Rp17e, Mekk4, Tas
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 26407
VEGA: 17
HGNC: HGNC:6856
Homologene: 31346
Nfkbil1
Name: nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor like 1
Synonyms: Def-7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 18038
HGNC: HGNC:7800
Homologene: 3671
Nmt1
Name: N-myristoyltransferase 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 18107
HGNC: HGNC:7857
Homologene: 69027
Tnks
Name: tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
Synonyms: 4930554K12Rik, D130072O21Rik, tankyrase 1, TANK1, mTNKS1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 21951
Homologene: 18405
Ubr1
Name: ubiquitin protein ligase E3 component n-recognin 1
Synonyms: E3 alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22222
Homologene: 7582
Itpr1
Name: inositol 1,4,5-trisphosphate receptor 1
Synonyms: P400, IP3R1, Pcp-1, Itpr-1, Ip3r, opt, InsP3R type I, Pcp1, wblo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 16438
HGNC: HGNC:6180
Homologene: 1673
Trappc10
Name: trafficking protein particle complex 10
Synonyms: LOC380642, B230307C21Rik, Tmem1, b2b2613Clo, b2b2416Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216131
VEGA: 10
Homologene: 37751
Rrp36
Name: ribosomal RNA processing 36
Synonyms: BC011248
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224823
VEGA: 17
Homologene: 40346
Grid2ip
Name: glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein 1
Synonyms: delphilin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 170935
Homologene: 15781
Fzd10
Name: frizzled class receptor 10
Synonyms: Fz-10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 93897
HGNC: HGNC:4039
Homologene: 21411
Sfrp5
Name: secreted frizzled-related sequence protein 5
Synonyms: SARP3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 54612
Homologene: 2268
Lrrk2
Name: leucine-rich repeat kinase 2
Synonyms: cI-46, LOC381026, 9330188B09Rik, D630001M17Rik, 4921513O20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 66725
Homologene: 18982
Hjurp
Name: Holliday junction recognition protein
Synonyms: C330011F01Rik, A730008H23Rik, 6430706D22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 381280
Homologene: 10184
Uqcc3
Name: ubiquinol-cytochrome c reductase complex assembly factor 3
Synonyms: Cbp4, AI462493
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 107197
VEGA: 19
Homologene: 84061
Igf2r
Name: insulin-like growth factor 2 receptor
Synonyms: Mpr300, CI-MPR, IGF-II/CI-MPR, M6P/IGF2R, CD222, mannose-6-phosphate receptor, cation independent
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 16004
HGNC: HGNC:5467
Homologene: 676
Hp1bp3
Name: heterochromatin protein 1, binding protein 3
Synonyms: Hp1bp74
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 15441
Homologene: 7774
Kirrel
Name: kirre like nephrin family adhesion molecule 1
Synonyms: Neph1, Kirrel1, 6720469N11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 170643
Homologene: 10089
Sympk
Name: symplekin
Synonyms: 4632415H16Rik, 1500016F02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 68188
Homologene: 37969
Plxna2
Name: plexin A2
Synonyms: OCT, Plxn2, 2810428A13Rik, PlexA2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 18845
HGNC: HGNC:9100
Homologene: 56427
Bpifb1
Name: BPI fold containing family B, member 1
Synonyms: von Ebner minor salivary protein, LPlunc1, U46068
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228801
Homologene: 50047
Dnah17
Name: dynein, axonemal, heavy chain 17
Synonyms: LOC382552, 2810003K23Rik, Dnahcl1, Dnahc17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 69926
HGNC: HGNC:2946
Homologene: 72102
Hsf5
Name: heat shock transcription factor family member 5
Synonyms: LOC327992
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 327992
Homologene: 52701
Cyp4a10
Name: cytochrome P450, family 4, subfamily a, polypeptide 10
Synonyms: RP1, Cyp4a, D4Rp1, Msp-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 13117
HGNC: HGNC:2642
Homologene: 128044
Olfr432
Name: olfactory receptor 432
Synonyms: GA_x6K02T2P20D-21124681-21123743, MOR123-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 258711
Homologene: 81532
Gm10801
Name: predicted gene 10801
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Vmn2r26
Name: vomeronasal 2, receptor 26
Synonyms: V2r1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 56552
Homologene: 135915
Umodl1
Name: uromodulin-like 1
Synonyms: D17Ertd488e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 52020
VEGA: 17
Homologene: 45466
Ros1
Name: Ros1 proto-oncogene
Synonyms: Ros-1, c-ros
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 19886
Homologene: 2207
Dnm3
Name: dynamin 3
Synonyms: B230343F03Rik, 9630020E24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 103967
Homologene: 22906
Slc35d3
Name: solute carrier family 35, member D3
Synonyms: 6230421J19Rik, Frcl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 76157
VEGA: 10
Homologene: 19123
Mpo
Name: myeloperoxidase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 17523
HGNC: HGNC:7218
Homologene: 55450
Sumf2
Name: sulfatase modifying factor 2
Synonyms: 2610040F05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 67902
Homologene: 41037
Trim43c
Name: tripartite motif-containing 43C
Synonyms: Trim43
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 666731
Homologene: 105432
Zscan12
Name: zinc finger and SCAN domain containing 12
Synonyms: Zfp96
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 22758
Homologene: 86980
Nin
Name: ninein
Synonyms: 3110068G20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 18080
Homologene: 40632
Dcbld2
Name: discoidin, CUB and LCCL domain containing 2
Synonyms: 1700055P21Rik, Esdn, CLCP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 73379
Homologene: 12499
Rin1
Name: Ras and Rab interactor 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 225870
VEGA: 19
Homologene: 3170
Tmem38b
Name: transmembrane protein 38B
Synonyms: 1600017F22Rik, D4Ertd89e, TRIC-B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 52076
Homologene: 10010
Lrrc14
Name: leucine rich repeat containing 14
Synonyms: E130306I01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223664
Homologene: 40970
Olfr430
Name: olfactory receptor 430
Synonyms: GA_x6K02T2P20D-21108443-21107490, MOR105-5P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 258713
Homologene: 17362
4933416C03Rik
Name: RIKEN cDNA 4933416C03 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Cep250
Name: centrosomal protein 250
Synonyms: Inmp, B230210E21Rik, Cep2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 16328
HGNC: HGNC:1859
Homologene: 38286
Aadacl4fm4
Name: AADACL4 family member 4
Synonyms: LOC230890, Gm436
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230890
Homologene: 135765
Lrrc45
Name: leucine rich repeat containing 45
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217366
Homologene: 17019
Slc25a54
Name: solute carrier family 25, member 54
Synonyms: 4930443G12Rik, SCaMC-1like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 74686
Homologene: 82464
Hace1
Name: HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1
Synonyms: A730034A22Rik, 1700042J16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 209462
Homologene: 10807
Olfr629
Name: olfactory receptor 629
Synonyms: GA_x6K02T2PBJ9-6466772-6465828, MOR26-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258818
Homologene: 105159
Optc
Name: opticin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 269120
HGNC: HGNC:8158
Homologene: 8652
Gm525
Name: predicted gene 525
Synonyms: LOC217071
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217071
Homologene: 129636
AC238940.3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Tulp1
Name: tubby like protein 1
Synonyms: Tulp1l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 22157
Homologene: 2491
Oxct1
Name: 3-oxoacid CoA transferase 1
Synonyms: 2610008O03Rik, Scot-s
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 67041
HGNC: HGNC:8527
Homologene: 377
D1Pas1
Name: DNA segment, Chr 1, Pasteur Institute 1
Synonyms: Pl10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 110957
Homologene: 135966
Gyg
Name: glycogenin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 27357
HGNC: HGNC:4699
Homologene: 31219
Olfr1215
Name: olfactory receptor 1215
Synonyms: GA_x6K02T2Q125-50482823-50481885, MOR233-13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258451
Homologene: 74071
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • GT to GTT, chromosome 1 at 88,266,524 bp
  • T to A, chromosome 1 at 133,901,182 bp
  • T to C, chromosome 1 at 135,161,362 bp
  • T to C, chromosome 1 at 162,084,130 bp
  • A to T, chromosome 1 at 174,050,510 bp
  • T to A, chromosome 1 at 174,069,581 bp
  • G to T, chromosome 1 at 186,968,280 bp
  • G to A, chromosome 1 at 194,794,910 bp
  • A to G, chromosome 2 at 89,002,033 bp
  • T to A, chromosome 2 at 98,664,016 bp
  • T to C, chromosome 2 at 120,916,470 bp
  • A to G, chromosome 2 at 154,215,322 bp
  • G to A, chromosome 2 at 155,992,632 bp
  • A to T, chromosome 3 at 20,155,025 bp
  • C to T, chromosome 3 at 87,089,151 bp
  • T to A, chromosome 3 at 109,116,504 bp
  • T to C, chromosome 4 at 53,854,398 bp
  • G to T, chromosome 4 at 115,524,783 bp
  • C to T, chromosome 4 at 138,221,707 bp
  • C to T, chromosome 4 at 144,670,128 bp
  • G to A, chromosome 5 at 128,602,412 bp
  • A to G, chromosome 5 at 129,849,979 bp
  • T to G, chromosome 5 at 143,386,039 bp
  • A to G, chromosome 6 at 108,394,841 bp
  • T to A, chromosome 6 at 124,025,979 bp
  • A to G, chromosome 7 at 19,047,522 bp
  • A to C, chromosome 7 at 103,740,587 bp
  • T to A, chromosome 8 at 34,940,812 bp
  • A to T, chromosome 9 at 88,583,078 bp
  • T to C, chromosome 10 at 19,848,859 bp
  • G to A, chromosome 10 at 45,711,508 bp
  • A to T, chromosome 10 at 52,194,848 bp
  • A to T, chromosome 10 at 78,210,403 bp
  • G to T, chromosome 10 at 116,112,635 bp
  • T to C, chromosome 11 at 77,976,882 bp
  • A to G, chromosome 11 at 87,631,682 bp
  • A to G, chromosome 11 at 87,801,040 bp
  • T to A, chromosome 11 at 89,075,004 bp
  • T to C, chromosome 11 at 103,052,233 bp
  • T to A, chromosome 11 at 104,153,551 bp
  • C to T, chromosome 11 at 118,080,849 bp
  • C to T, chromosome 11 at 120,718,677 bp
  • C to T, chromosome 12 at 70,078,242 bp
  • A to G, chromosome 13 at 21,368,630 bp
  • G to A, chromosome 13 at 120,154,832 bp
  • T to A, chromosome 15 at 4,037,119 bp
  • T to C, chromosome 15 at 76,713,565 bp
  • T to A, chromosome 15 at 91,767,461 bp
  • T to C, chromosome 16 at 58,465,338 bp
  • T to C, chromosome 17 at 12,235,993 bp
  • T to C, chromosome 17 at 12,705,829 bp
  • T to C, chromosome 17 at 28,353,709 bp
  • T to C, chromosome 17 at 30,992,069 bp
  • G to T, chromosome 17 at 35,220,956 bp
  • G to T, chromosome 17 at 46,672,806 bp
  • G to T, chromosome 19 at 5,052,974 bp
  • C to T, chromosome 19 at 8,880,705 bp
  • T to G, chromosome 19 at 42,201,818 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
(Deceased) Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3930 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040917-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.