Beutler Mutagenetix

Strain Name:
C57BL/6J-MtgxR3975Btlr/Mmmh
Stock Number:
040939-MU
Citation ID:
RRID:MMRRC_040939-MU
Other Names:
R3975 (G1), C57BL/6J-MtgxR3975Btlr
Major Collection:

Gene Information

Adam23
Name: a disintegrin and metallopeptidase domain 23
Synonyms: MDC3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 23792
HGNC: HGNC:202
Homologene: 2826
Armc9
Name: armadillo repeat containing 9
Synonyms: 3830422A13Rik, 5730415N24Rik, 4831423D23Rik, 4930438O05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 78795
Homologene: 11847
Lrba
Name: LPS-responsive beige-like anchor
Synonyms: D3Ertd775e, Lba
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 80877
HGNC: HGNC:1742
Homologene: 36205
Tsc22d1
Name: TSC22 domain family, member 1
Synonyms: TSC-22, Egr5, Tgfb1i4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 21807
Homologene: 7573
Arap2
Name: ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
Synonyms: Centd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 212285
Homologene: 9064
Rara
Name: retinoic acid receptor, alpha
Synonyms: RAR alpha 1, RARalpha1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 19401
HGNC: HGNC:9864
Homologene: 20262
Copa
Name: coatomer protein complex subunit alpha
Synonyms: xenin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 12847
HGNC: HGNC:2230
Homologene: 3218
Mdn1
Name: midasin AAA ATPase 1
Synonyms: LOC213784, D4Abb1e, 4833432B22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 100019
Homologene: 39689
Crot
Name: carnitine O-octanoyltransferase
Synonyms: 1200003H03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 74114
HGNC: HGNC:2366
Homologene: 10899
Cyp51
Name: cytochrome P450, family 51
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 13121
HGNC: HGNC:2649
Homologene: 55488
Gpbp1l1
Name: GC-rich promoter binding protein 1-like 1
Synonyms: 5330440M15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 77110
Homologene: 84840
Otof
Name: otoferlin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 83762
HGNC: HGNC:8515
Homologene: 12892
Smc6
Name: structural maintenance of chromosomes 6
Synonyms: 2810489L22Rik, Smc6l1, 3830418C19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 67241
VEGA: 12
Homologene: 41575
Rps6
Name: ribosomal protein S6
Synonyms: S6R
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 20104
Homologene: 85949
Tap1
Name: transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
Synonyms: Ham1, Tap-1, Ham-1, RING4, TAP, PSF-1, MTP1, Abcb2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 21354
HGNC: HGNC:43
Homologene: 495
Smad4
Name: SMAD family member 4
Synonyms: D18Wsu70e, DPC4, Madh4, Dpc4, Smad 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 17128
HGNC: HGNC:6770
Homologene: 31310
Cenpe
Name: centromere protein E
Synonyms: CENP-E, 312kDa, Kif10, N-7 kinesin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229841
HGNC: HGNC:1856
Homologene: 20429
Smad6
Name: SMAD family member 6
Synonyms: Smad 6, b2b390Clo, Madh6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 17130
HGNC: HGNC:6772
Homologene: 4079
Reln
Name: reelin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 19699
HGNC: HGNC:9957
Homologene: 3699
Ttn
Name: titin
Synonyms: shru, connectin, mdm, 2310057K23Rik, D330041I19Rik, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, L56, 2310074I15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 22138
Homologene: 130650
Dnah6
Name: dynein, axonemal, heavy chain 6
Synonyms: A730004I20Rik, Dnahc6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 330355
HGNC: HGNC:2951
Homologene: 15221
Orm3
Name: orosomucoid 3
Synonyms: Orm-3, Agp-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 18407
HGNC: HGNC:8499
Homologene: 130632
Zim1
Name: zinc finger, imprinted 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 22776
HGNC: null
Homologene: 129793
Col27a1
Name: collagen, type XXVII, alpha 1
Synonyms: 5730512J02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 373864
Homologene: 69400
Tesk1
Name: testis specific protein kinase 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 21754
Homologene: 4577
Sis
Name: sucrase isomaltase (alpha-glucosidase)
Synonyms: sucrase-isomaltase, 2010204N08Rik, Si-s
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 69983
Homologene: 37424
Adcy2
Name: adenylate cyclase 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 210044
VEGA: 13
HGNC: HGNC:233
Homologene: 75133
Umodl1
Name: uromodulin-like 1
Synonyms: D17Ertd488e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 52020
VEGA: 17
Homologene: 45466
Sorbs2
Name: sorbin and SH3 domain containing 2
Synonyms: 2010203O03Rik, 9430041O17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 234214
Homologene: 83295
Plcl1
Name: phospholipase C-like 1
Synonyms: PRIP-1, PLC-L, C230017K02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 227120
HGNC: HGNC:9063
Homologene: 38155
Bckdha
Name: branched chain ketoacid dehydrogenase E1, alpha polypeptide
Synonyms: BCKAD E1[a]
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 12039
HGNC: HGNC:986
Homologene: 569
Golgb1
Name: golgi autoantigen, golgin subfamily b, macrogolgin 1
Synonyms: Giantin, Gm6840, 6330407A06Rik, C130074L01Rik, F730017E11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 224139
HGNC: HGNC:4429
Homologene: 68401
Rp1l1
Name: retinitis pigmentosa 1 homolog like 1
Synonyms: Dcdc4, Rp1hl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 271209
VEGA: 14
Homologene: 105870
Greb1l
Name: growth regulation by estrogen in breast cancer-like
Synonyms: mKIAA4095, AK220484
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 381157
Homologene: 73393
Olfr1090
Name: olfactory receptor 1090
Synonyms: GA_x6K02T2Q125-48247345-48246404, MOR188-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258844
HGNC: null
Homologene: 17413
Cacna2d4
Name: calcium channel, voltage-dependent, alpha 2/delta subunit 4
Synonyms: 5730412N02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 319734
Homologene: 26544
Pex5l
Name: peroxisomal biogenesis factor 5-like
Synonyms: Pex2, 1700016J08Rik, PXR2, TRIP8b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 58869
Homologene: 9562
Olfr693
Name: olfactory receptor 693
Synonyms: GA_x6K02T2PBJ9-9055944-9054994, MOR283-8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 258445
HGNC: null
Homologene: null
Olfr134
Name: olfactory receptor 134
Synonyms: GA_x6K02T2PSCP-2623613-2624551, MOR256-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 258829
HGNC: null
Homologene: 110603
Fam129a
Name: family with sequence similarity 129, member A
Synonyms: Niban
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 63913
Homologene: 62170
AC162391.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
Fbh1
Name: F-box DNA helicase 1
Synonyms: Fbxo18, Fbx18
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 50755
Homologene: 9272
Olfr141
Name: olfactory receptor 141
Synonyms: MOR179-5, K17, GA_x6K02T2Q125-48299679-48298702
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 257913
HGNC: null
Homologene: 28042
Bfsp2
Name: beaded filament structural protein 2, phakinin
Synonyms: CP49
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 107993
HGNC: HGNC:1041
Homologene: 20791
Mfsd11
Name: major facilitator superfamily domain containing 11
Synonyms: 2600014M03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 69900
Homologene: 11517
Slx1b
Name: SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)
Synonyms: 4833422P03Rik, 1110030E23Rik, 2410170E21Rik, Giyd2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 75764
Homologene: 11434
Clca1
Name: chloride channel accessory 1
Synonyms: Clca3, gob-5, gob5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 23844
HGNC: HGNC:2015
Homologene: 984
Thrb
Name: thyroid hormone receptor beta
Synonyms: Thrb1, Nr1a2, T3Rbeta, Thrb2, c-erbAbeta, TR beta, T3R[b]
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 21834
Homologene: 36025
Akr1b10
Name: aldo-keto reductase family 1, member B10 (aldose reductase)
Synonyms: 2310005E10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 67861
Homologene: 128412
Gdf2
Name: growth differentiation factor 2
Synonyms: Bmp9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 12165
VEGA: 14
HGNC: HGNC:4217
Homologene: 32299
Rpe65
Name: retinal pigment epithelium 65
Synonyms: rd12, Mord1, A930029L06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 19892
Homologene: 20108
Gpx6
Name: glutathione peroxidase 6
Synonyms: olfactory, 1700020G18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 75512
HGNC: HGNC:4558
Homologene: 130008
Ccn6
Name: cellular communication network factor 6
Synonyms: LOC327743, Wisp3, CCN6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 327743
VEGA: 10
Homologene: 77038
Nat8f4
Name: N-acetyltransferase 8 (GCN5-related) family member 4
Synonyms: 1700019G17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 75541
HGNC: null
Homologene: 136346
Crb2
Name: crumbs family member 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 241324
Homologene: 45474
Svbp
Name: small vasohibin binding protein
Synonyms: 2410005K17Rik, Svbp, Ccdc23
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 69216
Homologene: 11546
Wipf1
Name: WAS/WASL interacting protein family, member 1
Synonyms: WIP, D2Ertd120e, Waspip
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 215280
Homologene: 86891
Prdm6
Name: PR domain containing 6
Synonyms: PRISM, LOC225518
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 225518
HGNC: HGNC:9350
Homologene: 79756
Nt5dc2
Name: 5'-nucleotidase domain containing 2
Synonyms: 2510015F01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 70021
VEGA: 14
Homologene: 11290
Ceacam16
Name: carcinoembryonic antigen-related cell adhesion molecule 16
Synonyms: LOC330483
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 330483
Homologene: 19857
Scrn3
Name: secernin 3
Synonyms: 4833415E20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 74616
Homologene: 11601
Gm10260
Name: predicted gene 10260
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 100039740
VEGA: 13
HGNC: null
Homologene: null
Bola3
Name: bolA-like 3 (E. coli)
Synonyms: 1810056O20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 78653
Homologene: 5288
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 55,698,215 bp
  • T to A, chromosome 1 at 63,547,729 bp
  • T to A, chromosome 1 at 86,244,551 bp
  • T to C, chromosome 1 at 151,649,335 bp
  • T to A, chromosome 1 at 172,121,245 bp
  • T to C, chromosome 2 at 11,767,210 bp
  • C to A, chromosome 2 at 37,793,668 bp
  • T to C, chromosome 2 at 73,335,777 bp
  • C to T, chromosome 2 at 73,437,169 bp
  • T to C, chromosome 2 at 76,876,653 bp
  • T to A, chromosome 2 at 86,754,543 bp
  • G to A, chromosome 2 at 86,806,460 bp
  • C to A, chromosome 3 at 33,015,015 bp
  • T to C, chromosome 3 at 72,943,635 bp
  • T to C, chromosome 3 at 86,351,255 bp
  • A to G, chromosome 3 at 135,235,225 bp
  • T to C, chromosome 3 at 135,238,472 bp
  • A to T, chromosome 3 at 145,032,639 bp
  • A to T, chromosome 3 at 159,604,585 bp
  • T to C, chromosome 4 at 32,761,380 bp
  • C to T, chromosome 4 at 43,445,786 bp
  • T to A, chromosome 4 at 63,293,535 bp
  • A to T, chromosome 4 at 63,356,158 bp
  • A to G, chromosome 4 at 86,856,813 bp
  • T to C, chromosome 4 at 116,570,985 bp
  • T to A, chromosome 4 at 119,195,893 bp
  • C to T, chromosome 5 at 4,091,877 bp
  • T to C, chromosome 5 at 8,977,541 bp
  • A to T, chromosome 5 at 21,995,366 bp
  • A to G, chromosome 5 at 30,370,712 bp
  • G to T, chromosome 5 at 62,748,894 bp
  • A to T, chromosome 6 at 7,983,149 bp
  • G to T, chromosome 6 at 34,392,496 bp
  • A to G, chromosome 6 at 73,121,992 bp
  • T to C, chromosome 6 at 83,351,267 bp
  • A to G, chromosome 6 at 85,901,070 bp
  • A to G, chromosome 6 at 119,278,173 bp
  • A to T, chromosome 7 at 6,677,130 bp
  • C to A, chromosome 7 at 19,853,612 bp
  • C to A, chromosome 7 at 25,631,433 bp
  • T to C, chromosome 7 at 106,677,785 bp
  • G to A, chromosome 7 at 126,691,807 bp
  • T to C, chromosome 8 at 45,772,710 bp
  • T to C, chromosome 8 at 107,263,014 bp
  • A to G, chromosome 9 at 64,020,930 bp
  • A to G, chromosome 9 at 103,480,072 bp
  • C to G, chromosome 10 at 39,155,098 bp
  • T to G, chromosome 11 at 98,970,569 bp
  • T to C, chromosome 11 at 116,859,606 bp
  • T to A, chromosome 12 at 11,274,074 bp
  • C to A, chromosome 13 at 21,317,658 bp
  • T to G, chromosome 13 at 68,672,027 bp
  • A to G, chromosome 14 at 18,033,456 bp
  • T to C, chromosome 14 at 31,138,875 bp
  • T to A, chromosome 14 at 33,944,834 bp
  • T to A, chromosome 14 at 64,030,309 bp
  • T to C, chromosome 14 at 76,418,609 bp
  • T to G, chromosome 16 at 36,918,571 bp
  • C to A, chromosome 17 at 30,984,789 bp
  • C to A, chromosome 17 at 34,189,567 bp
  • A to G, chromosome 17 at 38,175,495 bp
  • A to G, chromosome 18 at 10,522,247 bp
  • T to C, chromosome 18 at 53,540,206 bp
  • G to T, chromosome 18 at 73,677,736 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R3975 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
040939-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.