Homozygous: Progressive loss of oocytes and female fertility. Accelerated reproductive aging in females.
Heterozygous: No observed phenotype
Zhou J, Stein P, Leu NA, Chm tal L, Xue J, Ma J, Huang X, Lampson MA, Schultz RM, Wang PJ. Accelerated reproductive aging in females lacking a novel centromere protein SYCP2L. 2015 Nov 15;24(22):6505-14. Epub 2015 Sep 11. (Medline PMID: 26362258)
|Viability and Fertility:||Female||Male||Comments|
|Homozygotes are viable:||Yes||Yes|
|Homozygotes are fertile:||Reduced||Yes||Reduced fertile period in homozygous females due to accelerated reproductive aging.|
|Heterozygotes are fertile:||Yes||Yes|
|Age Reproductive Decline:||6 to 8 months||Undetermined|
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