Strain Name:
C57BL/6J-MtgxR4573Btlr/Mmmh
Stock Number:
041598-MU
Citation ID:
RRID:MMRRC_041598-MU
Other Names:
R4573 (G1), C57BL/6J-MtgxR4573Btlr
Major Collection:

Gene Information

Myo5a
Name: myosin VA
Synonyms: 9630007J19Rik, MyoVA, flail, MVa, Myo5, Dbv
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 17918
HGNC: HGNC:7602
Homologene: 20100
Pou2f1
Name: POU domain, class 2, transcription factor 1
Synonyms: Oct-1A, Otf1, Otf-1, Oct1, oct-1, 2810482H01Rik, Oct-1C, Oct-1z, Oct-1B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 18986
HGNC: HGNC:9212
Homologene: 37658
Gsr
Name: glutathione reductase
Synonyms: Gr1, Gr-1, D8Ertd238e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 14782
HGNC: HGNC:4623
Homologene: 531
Ppp1r14c
Name: protein phosphatase 1, regulatory inhibitor subunit 14C
Synonyms: 6330514J04Rik, KEPI
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 76142
VEGA: 10
Homologene: 12805
Mthfd1
Name: methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase
Synonyms: E430024A07Rik, Mthfd, DCS
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 108156
VEGA: 12
HGNC: HGNC:7432
Homologene: 55940
Prrc2b
Name: proline-rich coiled-coil 2B
Synonyms: 5830434P21Rik, Bat2l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 227723
Homologene: 106649
Paics
Name: phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase
Synonyms: AIRC, ADE2H1, 2610511I09Rik, PAIS
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 67054
HGNC: HGNC:8587
Homologene: 4710
Ppil2
Name: peptidylprolyl isomerase (cyclophilin)-like 2
Synonyms: C130078A06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 66053
HGNC: HGNC:9261
Homologene: 8643
Rabep1
Name: rabaptin, RAB GTPase binding effector protein 1
Synonyms: rabaptin-5, neurocrescin, RAB5 effector protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 54189
Homologene: 3451
Mycbp2
Name: MYC binding protein 2, E3 ubiquitin protein ligase
Synonyms: Phr1, C130061D10Rik, Pam
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 105689
Homologene: 9005
Sec24d
Name: Sec24 related gene family, member D (S. cerevisiae)
Synonyms: LOC383951, 2310020L09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 69608
Homologene: 40986
Cdc42bpb
Name: CDC42 binding protein kinase beta
Synonyms: DMPK-like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 217866
VEGA: 12
HGNC: HGNC:1738
Homologene: 55945
Cep290
Name: centrosomal protein 290
Synonyms: Nphp6, b2b1752Clo, Kiaa, b2b1454Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 216274
VEGA: 10
Homologene: 77213
Chka
Name: choline kinase alpha
Synonyms: EtnK-alpha, ChoK, Chk, CK/EK-alpha, choline/ethanolamine kinase alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 12660
HGNC: HGNC:1937
Homologene: 88575
Aspm
Name: abnormal spindle microtubule assembly
Synonyms: Sha1, D330028K02Rik, Calmbp1, Aspm, MCPH5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 12316
Homologene: 7650
Pcmtd1
Name: protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
Synonyms: A030012M09Rik, 8430411F12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 319263
Homologene: 14180
Ncor2
Name: nuclear receptor co-repressor 2
Synonyms: SMRT, SMRTe
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 20602
HGNC: HGNC:7673
Homologene: 31370
Dyrk1a
Name: dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a
Synonyms: 2310043O08Rik, D16Ertd493e, Mnbh, D16Ertd272e, Dyrk
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 13548
HGNC: HGNC:3091
Homologene: 55576
Lrp6
Name: low density lipoprotein receptor-related protein 6
Synonyms: skam26Jus, skax26, Cd, ska26
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 16974
HGNC: HGNC:6698
Homologene: 1747
Yap1
Name: yes-associated protein 1
Synonyms: Yki, Yap, yorkie
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 22601
Homologene: 4452
Trio
Name: triple functional domain (PTPRF interacting)
Synonyms: Solo, 6720464I07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 223435
VEGA: 15
Homologene: 20847
Gucy1a1
Name: guanylate cyclase 1, soluble, alpha 1
Synonyms: alpha 1 sGC, sGC-alpha1, 1200016O07Rik, Gucy1a3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 60596
HGNC: HGNC:4685
Homologene: 37360
Syt7
Name: synaptotagmin VII
Synonyms: B230112P13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 54525
VEGA: 19
Homologene: 20889
Ppp1r2
Name: protein phosphatase 1, regulatory inhibitor subunit 2
Synonyms: 0610025N14Rik, 2310007G06Rik, 4930440J04Rik, 5430408E15Rik, I-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 66849
HGNC: HGNC:9288
Homologene: 4546
Arsg
Name: arylsulfatase G
Synonyms: 6330406P08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 74008
Homologene: 8978
Mrpl2
Name: mitochondrial ribosomal protein L2
Synonyms: MRP-L14, Rpml14, CGI-22
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 27398
Homologene: 69198
Dnah8
Name: dynein, axonemal, heavy chain 8
Synonyms: Hst6.7b, P1-Loop, Dnahc8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 13417
VEGA: 17
HGNC: HGNC:2952
Homologene: 1049
Sept10
Name: septin 10
Synonyms: 4921515A04Rik, 9430099J10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 103080
VEGA: 10
Homologene: 27035
Zfp157
Name: zinc finger protein 157
Synonyms: A630094N24Rik, Roma, 2610020C11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 72154
Homologene: 57009
Pnpla7
Name: patatin-like phospholipase domain containing 7
Synonyms: E430013P11Rik, NRE
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 241274
Homologene: 62431
Atad2b
Name: ATPase family, AAA domain containing 2B
Synonyms: D530031C13Rik, 1110014E10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 320817
VEGA: 12
Homologene: 86351
Slamf7
Name: SLAM family member 7
Synonyms: 4930560D03Rik, CS1, 19A24, 19A, novel Ly9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 75345
Homologene: 49660
Vat1
Name: vesicle amine transport 1
Synonyms: VAT-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 26949
Homologene: 36200
Adam15
Name: a disintegrin and metallopeptidase domain 15 (metargidin)
Synonyms: metargidin, MDC15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 11490
HGNC: HGNC:193
Homologene: 2829
H2-K1
Name: histocompatibility 2, K1, K region
Synonyms: H-2K
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 14972
HGNC: HGNC:4931
Homologene: 128352
Tnfaip2
Name: tumor necrosis factor, alpha-induced protein 2
Synonyms: Tnfip2, Exoc3l3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 21928
Homologene: 4583
Dnah6
Name: dynein, axonemal, heavy chain 6
Synonyms: A730004I20Rik, Dnahc6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 330355
HGNC: HGNC:2951
Homologene: 15221
Trpm3
Name: transient receptor potential cation channel, subfamily M, member 3
Synonyms: LTRPC3, 6330504P12Rik, MLSN2, melastatin 2, B930001P07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 226025
VEGA: 19
Homologene: 62287
Fer1l6
Name: fer-1-like 6 (C. elegans)
Synonyms: EG631797
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 631797
Homologene: 53396
Asic3
Name: acid-sensing (proton-gated) ion channel 3
Synonyms: Accn3, DRASIC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 171209
HGNC: HGNC:101
Homologene: 20999
Sis
Name: sucrase isomaltase (alpha-glucosidase)
Synonyms: sucrase-isomaltase, 2010204N08Rik, Si-s
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 69983
Homologene: 37424
Elmod1
Name: ELMO/CED-12 domain containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 270162
VEGA: 9
Homologene: 10280
Fsip2
Name: fibrous sheath-interacting protein 2
Synonyms: OTTMUSG00000013335
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 241516
Homologene: 110349
Ryr3
Name: ryanodine receptor 3
Synonyms: calcium release channel isoform 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 20192
Homologene: 68151
Cdhr3
Name: cadherin-related family member 3
Synonyms: 1110049B09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 68764
VEGA: 12
Homologene: 45146
Ptchd4
Name: patched domain containing 4
Synonyms: 3110082D06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 627626
VEGA: 17
Homologene: 78322
Bpifb2
Name: BPI fold containing family B, member 2
Synonyms: 2310034L21Rik, Bpil1, 2310069A01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 66557
Homologene: 11884
Hsd3b5
Name: hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5
Synonyms: 3(beta)HSDV
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 15496
Homologene: 104115
Tshz1
Name: teashirt zinc finger family member 1
Synonyms: Sdccag33, NY-CO-33, teashirt1, Tsh1, 5730407I04Rik, D18Bwg1409e, Mtsh1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 110796
Homologene: 4227
Vmn2r5
Name: vomeronasal 2, receptor 5
Synonyms: EG667060
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 667060
Olfr50
Name: olfactory receptor 50
Synonyms: GA_x6K02T2NLDC-33487752-33488690, MOR136-6, ID3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 18350
Homologene: 74212
Olfr353
Name: olfactory receptor 353
Synonyms: MOR127-3, GA_x6K02T2NLDC-33585366-33584431
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258943
HGNC: HGNC:8221
Homologene: 115503
Slc6a7
Name: solute carrier family 6 (neurotransmitter transporter, L-proline), member 7
Synonyms: Prot
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 240332
VEGA: 18
Homologene: 8592
Mcemp1
Name: mast cell expressed membrane protein 1
Synonyms: 1810033B17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 69189
Homologene: 52162
Nrap
Name: nebulin-related anchoring protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 18175
HGNC: HGNC:7988
Homologene: 4499
Atp1a2
Name: ATPase, Na+/K+ transporting, alpha 2 polypeptide
Synonyms: Atpa-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 98660
HGNC: HGNC:800
Homologene: 47947
Ofcc1
Name: orofacial cleft 1 candidate 1
Synonyms: Opo, ojoplano
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 218165
VEGA: 13
Homologene: 125376
Ces1d
Name: carboxylesterase 1D
Synonyms: Ces3, TGH
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 104158
HGNC: HGNC:1863
Homologene: 35606
Mul1
Name: mitochondrial ubiquitin ligase activator of NFKB 1
Synonyms: 0610009K11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 68350
Homologene: 11576
Ap1m2
Name: adaptor protein complex AP-1, mu 2 subunit
Synonyms: D9Ertd818e, [m]1B, mu1B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 11768
VEGA: 9
HGNC: HGNC:558
Homologene: 55906
Tm4sf1
Name: transmembrane 4 superfamily member 1
Synonyms: M3s1, L6, L6 antigen, 12A8 target antigen
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 17112
Homologene: 7409
Arhgef33
Name: Rho guanine nucleotide exchange factor (GEF) 33
Synonyms: Gm941, LOC381112
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 381112
VEGA: 17
Homologene: 55190
Osbpl5
Name: oxysterol binding protein-like 5
Synonyms: 1110006M06Rik, Obph1, ORP5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 79196
Homologene: 98024
Fam129a
Name: family with sequence similarity 129, member A
Synonyms: Niban
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 63913
Homologene: 62170
Mterf1a
Name: mitochondrial transcription termination factor 1a
Synonyms: 9230106K09Rik, Mterf, 4931431L11Rik, Mterf1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 545725
Homologene: 5073
Rgs6
Name: regulator of G-protein signaling 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 50779
Homologene: 68385
Pgbd5
Name: piggyBac transposable element derived 5
Synonyms: 2900019M05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 209966
Homologene: 11583
Carf
Name: calcium response factor
Synonyms: Als2cr8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 241066
Homologene: 11689
Vmn1r70
Name: vomeronasal 1 receptor 70
Synonyms: V1rl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 171262
Homologene: 74361
Zbed6
Name: zinc finger, BED type containing 6
Synonyms: MGR, Gm8466, similar to Zinc finger BED domain containing protein 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 667118
Homologene: 130066
Akr1b10
Name: aldo-keto reductase family 1, member B10 (aldose reductase)
Synonyms: 2310005E10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 67861
Homologene: 128412
Cd1d2
Name: CD1d2 antigen
Synonyms: Cd1b, CD1.2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 12480
HGNC: HGNC:1637
C1s2
Name: complement component 1, s subcomponent 2
Synonyms: Gm5077
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 317677
HGNC: HGNC:1247
Homologene: 1314
Cyp4f37
Name: cytochrome P450, family 4, subfamily f, polypeptide 37
Synonyms: Gm9705
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 677156
VEGA: 17
Homologene: 135840
March5
Name: membrane-associated ring finger (C3HC4) 5
Synonyms: MITOL, 1810015H18Rik, MARCH-V, E130202O05Rik, 2310008I22Rik, 5730499H23Rik, Rnf153, 2700055A20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 69104
Homologene: 9862
Hoxb13
Name: homeobox B13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 15408
HGNC: HGNC:5112
Homologene: 4640
Cbarp
Name: calcium channel, voltage-dependent, beta subunit associated regulatory protein
Synonyms: Dos, R29144/1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 100503659
Homologene: 82309
Slc15a1
Name: solute carrier family 15 (oligopeptide transporter), member 1
Synonyms: PECT1, PEPT1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 56643
VEGA: 14
Homologene: 38006
Rpl12
Name: ribosomal protein L12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 269261
Homologene: 128047
Adam1b
Name: a disintegrin and metallopeptidase domain 1b
Synonyms: fertilin alpha, PH-30 alpha, Ftna
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 280667
Homologene: 136485
Cltb
Name: clathrin, light polypeptide (Lcb)
Synonyms: 2310046E19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 74325
HGNC: HGNC:2091
Homologene: 37532
Dhrs9
Name: dehydrogenase/reductase (SDR family) member 9
Synonyms: Rdh15, C730025I08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 241452
Homologene: 26079
Gm5709
Name: predicted gene 5709
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 435732
Homologene: 33954
Ninj1
Name: ninjurin 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 18081
HGNC: HGNC:7824
Homologene: 88815
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 7,120,367 bp
  • G to T, chromosome 1 at 60,148,112 bp
  • A to G, chromosome 1 at 133,659,389 bp
  • G to T, chromosome 1 at 139,479,507 bp
  • T to C, chromosome 1 at 151,703,766 bp
  • G to A, chromosome 1 at 165,913,261 bp
  • T to C, chromosome 1 at 171,636,366 bp
  • T to C, chromosome 1 at 172,278,637 bp
  • T to C, chromosome 2 at 25,050,873 bp
  • A to T, chromosome 2 at 32,221,434 bp
  • T to G, chromosome 2 at 32,962,038 bp
  • T to A, chromosome 2 at 36,793,479 bp
  • T to C, chromosome 2 at 36,890,190 bp
  • C to A, chromosome 2 at 69,397,641 bp
  • A to T, chromosome 2 at 82,986,166 bp
  • C to T, chromosome 2 at 112,755,174 bp
  • C to T, chromosome 2 at 153,889,492 bp
  • A to T, chromosome 3 at 57,294,785 bp
  • A to T, chromosome 3 at 59,635,636 bp
  • C to T, chromosome 3 at 64,503,918 bp
  • T to C, chromosome 3 at 72,928,237 bp
  • A to G, chromosome 3 at 82,108,922 bp
  • A to G, chromosome 3 at 86,987,554 bp
  • T to C, chromosome 3 at 89,345,986 bp
  • T to C, chromosome 3 at 98,619,648 bp
  • G to A, chromosome 3 at 123,358,870 bp
  • T to C, chromosome 4 at 138,436,349 bp
  • G to A, chromosome 5 at 3,891,119 bp
  • A to G, chromosome 5 at 24,417,192 bp
  • T to C, chromosome 5 at 76,956,603 bp
  • A to C, chromosome 5 at 121,500,793 bp
  • A to T, chromosome 5 at 125,055,825 bp
  • A to G, chromosome 5 at 138,456,929 bp
  • T to C, chromosome 6 at 34,392,129 bp
  • T to A, chromosome 6 at 73,086,181 bp
  • T to C, chromosome 6 at 124,628,243 bp
  • G to A, chromosome 6 at 134,470,730 bp
  • C to A, chromosome 7 at 10,633,629 bp
  • C to A, chromosome 7 at 143,694,316 bp
  • A to G, chromosome 8 at 3,665,835 bp
  • A to G, chromosome 8 at 33,693,853 bp
  • A to C, chromosome 8 at 93,181,534 bp
  • G to A, chromosome 8 at 124,376,227 bp
  • T to C, chromosome 9 at 7,934,681 bp
  • T to C, chromosome 9 at 21,305,758 bp
  • T to C, chromosome 9 at 53,925,972 bp
  • A to T, chromosome 9 at 75,201,297 bp
  • A to G, chromosome 10 at 3,463,416 bp
  • T to A, chromosome 10 at 59,192,329 bp
  • G to T, chromosome 10 at 80,131,411 bp
  • A to G, chromosome 10 at 100,518,850 bp
  • G to C, chromosome 11 at 70,917,751 bp
  • A to G, chromosome 11 at 96,194,951 bp
  • A to T, chromosome 11 at 101,460,615 bp
  • T to C, chromosome 11 at 109,517,282 bp
  • T to C, chromosome 12 at 4,954,663 bp
  • A to T, chromosome 12 at 33,068,153 bp
  • A to G, chromosome 12 at 76,294,138 bp
  • T to A, chromosome 12 at 83,066,015 bp
  • A to T, chromosome 12 at 111,323,141 bp
  • T to C, chromosome 12 at 111,450,712 bp
  • G to A, chromosome 13 at 40,015,388 bp
  • A to G, chromosome 13 at 49,194,987 bp
  • C to T, chromosome 13 at 54,598,761 bp
  • G to T, chromosome 14 at 103,346,297 bp
  • A to G, chromosome 14 at 121,487,029 bp
  • CCTTCTTCTTCT to CCTTCTTCT, chromosome 15 at 27,772,998 bp
  • G to A, chromosome 15 at 58,626,280 bp
  • A to G, chromosome 16 at 17,093,045 bp
  • A to G, chromosome 16 at 31,260,637 bp
  • A to G, chromosome 16 at 94,692,023 bp
  • T to C, chromosome 17 at 30,700,406 bp
  • A to G, chromosome 17 at 32,629,087 bp
  • T to C, chromosome 17 at 33,996,469 bp
  • T to C, chromosome 17 at 42,502,777 bp
  • G to T, chromosome 17 at 46,649,041 bp
  • T to C, chromosome 17 at 80,365,282 bp
  • A to T, chromosome 18 at 61,002,181 bp
  • A to T, chromosome 18 at 84,015,082 bp
  • A to G, chromosome 19 at 3,885,960 bp
  • C to T, chromosome 19 at 10,439,212 bp
  • C to T, chromosome 19 at 22,902,142 bp
  • T to A, chromosome 19 at 37,220,394 bp
  • T to C, chromosome 19 at 56,342,338 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4573 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
041598-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.