Strain Name:
C57BL/6J-MtgxR4290Btlr/Mmmh
Stock Number:
041655-MU
Citation ID:
RRID:MMRRC_041655-MU
Other Names:
R4290 (G1), C57BL/6J-MtgxR4290Btlr
Major Collection:

Gene Information

Zfa-ps
Name: zinc finger protein, autosomal, pseudogene
Synonyms: Zfa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 22639
HGNC: null
Homologene: null
Nes
Name: nestin
Synonyms: RC2, Ifaprc2, ESTM46, Marc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 18008
HGNC: HGNC:7756
Homologene: 136487
Lmf1
Name: lipase maturation factor 1
Synonyms: Tmem112, 2400010G15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 76483
Homologene: 23384
Vcan
Name: versican
Synonyms: DPEAAE, heart defect, 5430420N07Rik, hdf, PG-M, Cspg2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 13003
HGNC: HGNC:2464
Homologene: 3228
En1
Name: engrailed 1
Synonyms: engrailed-1, Mo-en.1, En-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 13798
HGNC: HGNC:3342
Homologene: 50663
Chrna9
Name: cholinergic receptor, nicotinic, alpha polypeptide 9
Synonyms: Acra9, Gm8311, 2410015I05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231252
Homologene: 9729
Sash1
Name: SAM and SH3 domain containing 1
Synonyms: A330076K04Rik, 1100001C18Rik, 2500002E12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 70097
Homologene: 69182
Phf14
Name: PHD finger protein 14
Synonyms: 5730446A07Rik, 1110001C23Rik, 4932409F11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 75725
Homologene: 8775
Nup210l
Name: nucleoporin 210-like
Synonyms: 4930548O11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 77595
Homologene: 28122
Bclaf1
Name: BCL2-associated transcription factor 1
Synonyms: 2810454G14Rik, 2610102K23Rik, 2700025J07Rik, 5730534O06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 72567
Homologene: 8832
Mapkapk3
Name: mitogen-activated protein kinase-activated protein kinase 3
Synonyms: MK3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 102626
HGNC: HGNC:6888
Homologene: 55836
Auts2
Name: autism susceptibility candidate 2
Synonyms: 2700063G02Rik, D830032G16Rik, A730011F23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 319974
Homologene: 22907
Brwd1
Name: bromodomain and WD repeat domain containing 1
Synonyms: Wdr9, D530019K20Rik, 5330419I02Rik, G1-403-16, repro5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 93871
Homologene: 23130
Arid1b
Name: AT rich interactive domain 1B (SWI-like)
Synonyms: 9330189K18Rik, B230217J03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 239985
Homologene: 32344
Ift80
Name: intraflagellar transport 80
Synonyms: 4921524P20Rik, Wdr56
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 68259
Homologene: 12253
Aldoa
Name: aldolase A, fructose-bisphosphate
Synonyms: Aldo1, Aldo-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 11674
HGNC: HGNC:414
Homologene: 123896
Gucy1a1
Name: guanylate cyclase 1, soluble, alpha 1
Synonyms: alpha 1 sGC, sGC-alpha1, 1200016O07Rik, Gucy1a3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 60596
HGNC: HGNC:4685
Homologene: 37360
Nrip1
Name: nuclear receptor interacting protein 1
Synonyms: RIP140, 8430438I05Rik, 6030458L20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 268903
HGNC: HGNC:8001
Homologene: 2606
Rps27a
Name: ribosomal protein S27A
Synonyms: 0610006J14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 78294
Homologene: 37715
Hepacam2
Name: HEPACAM family member 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 101202
Homologene: 18724
Srsf6
Name: serine/arginine-rich splicing factor 6
Synonyms: 1210001E11Rik, Sfrs6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 67996
Homologene: 110783
Ttf2
Name: transcription termination factor, RNA polymerase II
Synonyms: 4632434F22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 74044
Homologene: 37826
Arid3b
Name: AT rich interactive domain 3B (BRIGHT-like)
Synonyms: Bdp, Dri2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 56380
Homologene: 4721
Lbr
Name: lamin B receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 98386
HGNC: HGNC:6518
Homologene: 2455
Dact2
Name: dishevelled-binding antagonist of beta-catenin 2
Synonyms: Dpr2, 2900084M21Rik, dapper2, Frd2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 240025
VEGA: 17
Homologene: 18237
Dlg3
Name: discs large MAGUK scaffold protein 3
Synonyms: SAP102, Dlgh3, DLG3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
Alteration at locus: Chemically Induced
NCBI: 53310
HGNC: HGNC:2902
Homologene: 41157
Ddr2
Name: discoidin domain receptor family, member 2
Synonyms: Ntrkr3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 18214
HGNC: HGNC:2731
Homologene: 68505
Kcnv1
Name: potassium channel, subfamily V, member 1
Synonyms: 2700023A03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 67498
VEGA: 15
Homologene: 22811
Fhdc1
Name: FH2 domain containing 1
Synonyms: 6330505N24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229474
Homologene: 18920
Itga2
Name: integrin alpha 2
Synonyms: DX5, CD49B, VLA-2 receptor, alpha 2 subunit
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 16398
VEGA: 13
HGNC: HGNC:6137
Homologene: 1662
Ttn
Name: titin
Synonyms: shru, connectin, mdm, 2310057K23Rik, D330041I19Rik, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, L56, 2310074I15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 22138
Homologene: 130650
Mccc1
Name: methylcrotonoyl-Coenzyme A carboxylase 1 (alpha)
Synonyms: 2310058B18Rik, MCCalpha, MCCA, 1810045E08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 72039
HGNC: HGNC:6936
Homologene: 10603
Kmt5b
Name: lysine methyltransferase 5B
Synonyms: Suv4-20h1, C630029K18Rik, Suv420h1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 225888
Homologene: 32351
Ush2a
Name: usherin
Synonyms: Ush2a, Ushrn, MUSH2A, A930037M10Rik, A930011D15Rik, LOC269160, LOC381317
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 22283
Homologene: 66151
Nlrp9a
Name: NLR family, pyrin domain containing 9A
Synonyms: D7Ertd565e, Nalp9a, Nalp-theta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233001
HGNC: null
Homologene: 116072
Plpp4
Name: phospholipid phosphatase 4
Synonyms: Ppapdc1a, LOC381925, C030048B12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 381925
Homologene: 38751
Slc22a21
Name: solute carrier family 22 (organic cation transporter), member 21
Synonyms: Slc22a9, Octn3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 56517
HGNC: null
Homologene: 137336
Pcdhb5
Name: protocadherin beta 5
Synonyms: PcdhbE, Pcdhb4A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 93876
HGNC: HGNC:8689
Homologene: 75103
Abcc9
Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 9
Synonyms: SUR2A, SUR2B, Sur2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 20928
HGNC: HGNC:60
Homologene: 56521
Kmt2b
Name: lysine (K)-specific methyltransferase 2B
Synonyms: Wbp7, 2610014H22Rik, Mll2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 75410
Homologene: 22838
Dpy19l1
Name: dpy-19-like 1 (C. elegans)
Synonyms: 1100001I19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 244745
Homologene: 14762
Olfr169
Name: olfactory receptor 169
Synonyms: MOR273-3P, GA_x54KRFPKG5P-16014972-16014031
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 258158
HGNC: null
Homologene: 128058
Olfr711
Name: olfactory receptor 711
Synonyms: MOR103-4, GA_x6K02T2PBJ9-9352783-9351839
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 259037
HGNC: null
Homologene: 128111
Ttc19
Name: tetratricopeptide repeat domain 19
Synonyms: 2010204O13Rik, 2810460C24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 72795
Homologene: 9831
Mindy2
Name: MINDY lysine 48 deubiquitinase 2
Synonyms: Fam63b, B230380D07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235461
VEGA: 9
Homologene: 101023
Atf6b
Name: activating transcription factor 6 beta
Synonyms: Crebl1, Creb-rp, ATF6beta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 12915
HGNC: HGNC:2349
Homologene: 31238
Olfr310
Name: olfactory receptor 310
Synonyms: MOR227-6P, GA_x6K02T2NHDJ-9838699-9839697
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 258222
HGNC: null
Homologene: 128066
Olfr1508
Name: olfactory receptor 1508
Synonyms: MOR244-4, GA_x6K02T2RJGY-520647-521579, MOR10, MOR244-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 57270
HGNC: HGNC:8296
Homologene: 10737
Cckar
Name: cholecystokinin A receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 12425
HGNC: HGNC:1570
Homologene: 37337
Man1c1
Name: mannosidase, alpha, class 1C, member 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230815
Homologene: 69303
Hddc2
Name: HD domain containing 2
Synonyms: 2310057G13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 69692
Homologene: 5431
Olfr1396
Name: olfactory receptor 1396
Synonyms: GA_x6K02T2QP88-6321048-6321995, MOR276-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 258334
Homologene: 28537
Cfap221
Name: cilia and flagella associated protein 221
Synonyms: Gm101, Pcdp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 226356
Homologene: 88578
Olfr926
Name: olfactory receptor 926
Synonyms: GA_x6K02T2PVTD-32573036-32573962, MOR171-8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 258811
VEGA: 9
HGNC: HGNC:8482
Homologene: 128215
Vmn2r101
Name: vomeronasal 2, receptor 101
Synonyms: EG627576
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 627576
HGNC: null
Homologene: 115024
Atpaf1
Name: ATP synthase mitochondrial F1 complex assembly factor 1
Synonyms: ATP11, ATP11p, 6330547J17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230649
Homologene: 41492
Bivm
Name: basic, immunoglobulin-like variable motif containing
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 246229
Homologene: 9783
Usp36
Name: ubiquitin specific peptidase 36
Synonyms: 2700002L06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 72344
Homologene: 11828
Stk32c
Name: serine/threonine kinase 32C
Synonyms: Pkek, YANK3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 57740
Homologene: 75157
Cox10
Name: heme A:farnesyltransferase cytochrome c oxidase assembly factor 10
Synonyms: 2410004F01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 70383
HGNC: HGNC:2260
Homologene: 80170
Kcna1
Name: potassium voltage-gated channel, shaker-related subfamily, member 1
Synonyms: MBK1, Mk-1, mceph, mouse brain potassium channel protein-1, Kv1.1, Shak
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 16485
HGNC: HGNC:6218
Homologene: 183
Vmn1r192
Name: vomeronasal 1 receptor 192
Synonyms: V1ri1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 252907
HGNC: null
Homologene: 110880
Olfr373
Name: olfactory receptor 373
Synonyms: GA_x6K02T2NUPS-231686-232630, MOR282-2, MOR282-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 258532
Homologene: 17287
Mettl5
Name: methyltransferase like 5
Synonyms: 2810410A08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 75422
Homologene: 8570
Il19
Name: interleukin 19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 329244
HGNC: HGNC:5990
Homologene: 17813
G730003C15Rik
Name: RIKEN cDNA G730003C15 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: null
HGNC: null
Homologene: null
Gm6124
Name: predicted gene 6124
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 620018
HGNC: null
Homologene: 45597
Xndc1
Name: Xrcc1 N-terminal domain containing 1
Synonyms: Xndr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 102443350
HGNC: null
Homologene: 128476
Rps15a-ps1
Name: ribosomal protein S15A, pseudogene 1
Synonyms: Gm7263
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 639162
HGNC: null
Homologene: null
Mir6963
Name: microRNA 6963
Synonyms: mmu-mir-6963
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 102466775
VEGA: 15
HGNC: null
Homologene: null
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 44,138,633 bp
  • A to G, chromosome 1 at 59,119,836 bp
  • A to G, chromosome 1 at 119,930,920 bp
  • C to A, chromosome 1 at 120,603,757 bp
  • T to A, chromosome 1 at 130,935,013 bp
  • A to G, chromosome 1 at 169,990,609 bp
  • C to T, chromosome 1 at 181,820,702 bp
  • C to T, chromosome 1 at 188,576,251 bp
  • T to C, chromosome 2 at 69,880,832 bp
  • A to T, chromosome 2 at 76,811,243 bp
  • T to C, chromosome 2 at 162,934,716 bp
  • A to G, chromosome 3 at 35,990,068 bp
  • A to G, chromosome 3 at 68,963,690 bp
  • A to T, chromosome 3 at 82,094,759 bp
  • C to A, chromosome 3 at 84,444,826 bp
  • A to G, chromosome 3 at 87,971,934 bp
  • A to T, chromosome 3 at 90,207,326 bp
  • T to C, chromosome 3 at 100,962,761 bp
  • A to T, chromosome 4 at 115,788,359 bp
  • T to A, chromosome 4 at 134,563,785 bp
  • A to G, chromosome 5 at 53,706,497 bp
  • A to G, chromosome 5 at 65,977,138 bp
  • A to G, chromosome 5 at 131,474,971 bp
  • T to A, chromosome 6 at 3,487,237 bp
  • C to T, chromosome 6 at 11,987,097 bp
  • T to C, chromosome 6 at 126,641,875 bp
  • T to C, chromosome 6 at 142,594,012 bp
  • A to G, chromosome 7 at 26,562,590 bp
  • A to T, chromosome 7 at 30,581,836 bp
  • A to T, chromosome 7 at 39,222,771 bp
  • A to T, chromosome 7 at 86,269,760 bp
  • T to A, chromosome 7 at 102,081,487 bp
  • A to C, chromosome 7 at 106,971,711 bp
  • A to G, chromosome 7 at 126,792,059 bp
  • A to G, chromosome 7 at 129,307,632 bp
  • T to C, chromosome 7 at 139,120,788 bp
  • A to G, chromosome 8 at 72,099,768 bp
  • G to A, chromosome 9 at 24,414,354 bp
  • A to G, chromosome 9 at 38,877,313 bp
  • A to T, chromosome 9 at 57,790,430 bp
  • T to A, chromosome 9 at 70,631,094 bp
  • T to C, chromosome 9 at 107,258,932 bp
  • A to G, chromosome 10 at 8,730,242 bp
  • A to G, chromosome 10 at 20,323,778 bp
  • A to T, chromosome 10 at 31,314,587 bp
  • A to T, chromosome 10 at 52,543,711 bp
  • A to G, chromosome 10 at 106,192,635 bp
  • A to G, chromosome 11 at 29,545,933 bp
  • T to A, chromosome 11 at 49,113,427 bp
  • T to C, chromosome 11 at 53,969,503 bp
  • A to G, chromosome 11 at 62,285,927 bp
  • A to T, chromosome 11 at 63,964,255 bp
  • G to A, chromosome 11 at 118,263,647 bp
  • T to A, chromosome 13 at 22,187,295 bp
  • A to G, chromosome 13 at 89,725,486 bp
  • G to A, chromosome 13 at 114,866,173 bp
  • T to C, chromosome 14 at 52,463,985 bp
  • G to A, chromosome 15 at 45,114,444 bp
  • C to T, chromosome 15 at 103,352,257 bp
  • A to T, chromosome 16 at 19,566,244 bp
  • A to G, chromosome 16 at 76,291,988 bp
  • G to A, chromosome 16 at 96,017,604 bp
  • C to A, chromosome 17 at 5,040,663 bp
  • C to T, chromosome 17 at 14,196,571 bp
  • A to T, chromosome 17 at 19,612,041 bp
  • T to C, chromosome 17 at 25,654,481 bp
  • T to A, chromosome 17 at 34,652,674 bp
  • T to A, chromosome 18 at 37,322,681 bp
  • T to C, chromosome 19 at 3,802,193 bp
  • A to T, chromosome X at 100,796,682 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4290 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
041655-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.