Strain Name:
C57BL/6J-MtgxR4457Btlr/Mmmh
Stock Number:
041717-MU
Citation ID:
RRID:MMRRC_041717-MU
Other Names:
R4457 (G1), C57BL/6J-MtgxR4457Btlr
Major Collection:

Gene Information

Hps5
Name: HPS5, biogenesis of lysosomal organelles complex 2 subunit 2
Synonyms: Hermansky-Pudlak syndrome 5, ruby eye 2, ru-2, ru2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 246694
Homologene: 35333
Zic4
Name: zinc finger protein of the cerebellum 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 22774
Homologene: 32075
Cdkn2d
Name: cyclin dependent kinase inhibitor 2D
Synonyms: p19, INK4d, p19INK4d, INK4d
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 12581
VEGA: 9
HGNC: HGNC:1790
Homologene: 36081
Resp18
Name: regulated endocrine-specific protein 18
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 19711
Homologene: 7516
Frrs1
Name: ferric-chelate reductase 1
Synonyms: Sdfr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 20321
Homologene: 40653
Gria4
Name: glutamate receptor, ionotropic, AMPA4 (alpha 4)
Synonyms: Gluralpha4, Glur4, spkw1, Glur-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 14802
HGNC: HGNC:4574
Homologene: 20227
Slc4a2
Name: solute carrier family 4 (anion exchanger), member 2
Synonyms: B3RP, Ae2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 20535
Homologene: 128699
Hspa4
Name: heat shock protein 4
Synonyms: Hsp110, 70kDa, Hsp70RY, APG-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 15525
HGNC: HGNC:5237
Homologene: 1624
Pogz
Name: pogo transposable element with ZNF domain
Synonyms: 9530006B08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229584
Homologene: 9022
Akap13
Name: A kinase (PRKA) anchor protein 13
Synonyms: 1700026G02Rik, 5830460E08Rik, 5730522G15Rik, AKAP-Lbc, PROTO-LBC, PROTO-LB, Ht31
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 75547
HGNC: HGNC:371
Homologene: 4903
Zgrf1
Name: zinc finger, GRF-type containing 1
Synonyms: 4930422G04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 71643
Homologene: 34708
Tet2
Name: tet methylcytosine dioxygenase 2
Synonyms: Ayu17-449, E130014J05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 214133
Homologene: 49498
Myo9b
Name: myosin IXb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 17925
HGNC: HGNC:7609
Homologene: 3058
Atg4c
Name: autophagy related 4C, cysteine peptidase
Synonyms: Apg4-C, autophagin 3, Apg4c, Autl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 242557
Homologene: 56296
Tbc1d13
Name: TBC1 domain family, member 13
Synonyms: 2600014A06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 70296
Homologene: 10068
Dnah8
Name: dynein, axonemal, heavy chain 8
Synonyms: Hst6.7b, P1-Loop, Dnahc8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 13417
VEGA: 17
HGNC: HGNC:2952
Homologene: 1049
Rnf4
Name: ring finger protein 4
Synonyms: Gtrgeo8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 19822
Homologene: 37711
Kat6a
Name: K(lysine) acetyltransferase 6A
Synonyms: 9930021N24Rik, Myst3, MOZ, Zfp220
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 244349
Homologene: 4924
Atp4a
Name: ATPase, H+/K+ exchanging, gastric, alpha polypeptide
Synonyms: H+K+-transporting alpha 1, H+/K+-ATPase alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 11944
HGNC: HGNC:819
Homologene: 68081
Mslnl
Name: mesothelin-like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 328783
VEGA: 17
Homologene: 18633
Pkp1
Name: plakophilin 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 18772
HGNC: HGNC:9023
Homologene: 253
Ttn
Name: titin
Synonyms: shru, connectin, mdm, 2310057K23Rik, D330041I19Rik, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, L56, 2310074I15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 22138
Homologene: 130650
Letmd1
Name: LETM1 domain containing 1
Synonyms: 1110019O13Rik, HCCR1, HCCR-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 68614
VEGA: 15
Homologene: 9128
Chn1
Name: chimerin 1
Synonyms: alpha1 chimaerin, alpha2 chimaerin, 1700112L09Rik, 0710001E19Rik, 2900046J01Rik, ARHGAP2, 0610007I19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 108699
HGNC: HGNC:1943
Homologene: 31056
Dnah12
Name: dynein, axonemal, heavy chain 12
Synonyms: Dnahc12, HL-19, DLP12, HL19, DHC3, 4921531P07Rik, Hdhc3, Dnahc7l, LOC380889
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 110083
HGNC: HGNC:2943
Homologene: 56821
Olfr1251
Name: olfactory receptor 1251
Synonyms: MOR231-15P, MOR231-24_p, GA_x6K02T2Q125-51109312-51108356
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 259145
Homologene: 74065
Fsip2
Name: fibrous sheath-interacting protein 2
Synonyms: OTTMUSG00000013335
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 241516
Homologene: 110349
Zan
Name: zonadhesin
Synonyms: Zan
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 22635
Homologene: 124417
Pcyox1l
Name: prenylcysteine oxidase 1 like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 240334
Homologene: 23429
Myh1
Name: myosin, heavy polypeptide 1, skeletal muscle, adult
Synonyms: myosin heavy chain 2X, IId, IId/x, Myhsf2, Myhs-f, Myhs-f2, MyHC-IId/x, A530084A17Rik, MYHC-IIX
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 17879
HGNC: HGNC:7567
Homologene: 133718
Arhgef5
Name: Rho guanine nucleotide exchange factor (GEF) 5
Synonyms: 2210412D05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 54324
Homologene: 66300
Tdrd7
Name: tudor domain containing 7
Synonyms: 5730495N10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 100121
Homologene: 8618
Htra4
Name: HtrA serine peptidase 4
Synonyms: B430206E18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 330723
Homologene: 17801
Fam227b
Name: family with sequence similarity 227, member B
Synonyms: 4930525F21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 75823
Homologene: 27384
Vwde
Name: von Willebrand factor D and EGF domains
Synonyms: LOC232585
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 232585
Homologene: 35456
Ndor1
Name: NADPH dependent diflavin oxidoreductase 1
Synonyms: NR1, 4930447P04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 78797
Homologene: 7144
Hoxb5
Name: homeobox B5
Synonyms: Hox-2.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 15413
HGNC: HGNC:5116
Homologene: 37585
Ivl
Name: involucrin
Synonyms: 1110019C06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 16447
HGNC: HGNC:6187
Homologene: 137207
Usp9y
Name: ubiquitin specific peptidase 9, Y chromosome
Synonyms: Fafl2, Dffry
Type: Gene
Species: Mus musculus (mouse)
Chromosome: Y
Alteration at locus: Chemically Induced
NCBI: 107868
Homologene: 68408
Lamp3
Name: lysosomal-associated membrane protein 3
Synonyms: DC-LAMP, 1200002D17Rik, Cd208, TSC403
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 239739
VEGA: 16
Homologene: 8670
Ehbp1l1
Name: EH domain binding protein 1-like 1
Synonyms: G430002G23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 114601
VEGA: 19
Homologene: 136059
Pif1
Name: PIF1 5'-to-3' DNA helicase
Synonyms: AI449441
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 208084
Homologene: 99775
Olfr331
Name: olfactory receptor 331
Synonyms: MOR275-4, GA_x6K02T2NKPP-912840-913784
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 100502887
Homologene: 133015
Eya4
Name: EYA transcriptional coactivator and phosphatase 4
Synonyms: B130023L16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 14051
VEGA: 10
HGNC: HGNC:3522
Homologene: 3025
Thrb
Name: thyroid hormone receptor beta
Synonyms: Thrb1, Nr1a2, T3Rbeta, Thrb2, c-erbAbeta, TR beta, T3R[b]
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 21834
Homologene: 36025
Sgms2
Name: sphingomyelin synthase 2
Synonyms: 4933405A16Rik, 5133401H06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 74442
Homologene: 32705
Dnah7c
Name: dynein, axonemal, heavy chain 7C
Synonyms: Dnahc7c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 100101919
Homologene: 41287
Ikzf2
Name: IKAROS family zinc finger 2
Synonyms: A730095J18Rik, Zfpn1a2, Helios
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 22779
Homologene: 22659
1700025G04Rik
Name: RIKEN cDNA 1700025G04 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 69399
Homologene: 12776
9030619P08Rik
Name: RIKEN cDNA 9030619P08 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 105892
Cmtr2
Name: cap methyltransferase 2
Synonyms: Ftsjd1, C730036L12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 234728
Homologene: 10144
Ndufa12
Name: NADH:ubiquinone oxidoreductase subunit A12
Synonyms: 2410011G03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 66414
Homologene: 10314
1700003F12Rik
Name: RIKEN cDNA 1700003F12 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 75480
Homologene: 136196
Pcdha9
Name: protocadherin alpha 9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 192161
HGNC: HGNC:8664
Homologene: 130700
Olfr577
Name: olfactory receptor 577
Synonyms: MOR7-2, GA_x6K02T2PBJ9-5685322-5684384
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 259113
Homologene: 64962
Gja10
Name: gap junction protein, alpha 10
Synonyms: Cx59, Cx-57, Cx57, connexin-57
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 14610
Homologene: 7733
Rab36
Name: RAB36, member RAS oncogene family
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 76877
HGNC: HGNC:9775
Homologene: 3610
1110008E08Rik
Name: RIKEN cDNA 1110008E08 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
Rpl31-ps17
Name: ribosomal protein L31, pseudogene 17
Synonyms: Gm16382
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 673582
Slc25a10
Name: solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10
Synonyms: Dic
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 27376
Homologene: 6519
Cfap73
Name: cilia and flagella associated protein 73
Synonyms: Gm5988, Ccdc42b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 546886
Homologene: 53205
Gm10045
Name: predicted pseudogene 10045
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 100043348
Homologene: 138779
Gm4956
Name: predicted gene 4956
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 241041
Olfr1174-ps
Name: olfactory receptor 1174, pseudogene
Synonyms: MOR174-18, GA_x6K02T2Q125-49796506-49795568
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 546769
Homologene: 77381
Gm2840
Name: predicted gene 2840
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 21,298,095 bp
  • A to G, chromosome 1 at 46,740,621 bp
  • T to C, chromosome 1 at 69,684,188 bp
  • A to G, chromosome 1 at 75,274,497 bp
  • CTCTTCTT to CTCTT, chromosome 1 at 135,875,624 bp
  • T to C, chromosome 1 at 151,921,054 bp
  • A to G, chromosome 2 at 25,248,116 bp
  • A to G, chromosome 2 at 30,135,438 bp
  • A to G, chromosome 2 at 73,613,083 bp
  • T to C, chromosome 2 at 76,946,913 bp
  • G to T, chromosome 2 at 82,990,776 bp
  • A to G, chromosome 2 at 88,310,829 bp
  • A to T, chromosome 2 at 89,667,083 bp
  • T to A, chromosome 2 at 126,146,268 bp
  • A to G, chromosome 2 at 154,549,887 bp
  • G to A, chromosome 3 at 92,572,366 bp
  • G to A, chromosome 3 at 94,856,063 bp
  • G to A, chromosome 3 at 116,896,728 bp
  • A to T, chromosome 3 at 127,595,929 bp
  • A to C, chromosome 3 at 131,325,016 bp
  • C to T, chromosome 3 at 133,485,563 bp
  • A to T, chromosome 4 at 32,601,073 bp
  • A to G, chromosome 4 at 46,007,526 bp
  • A to G, chromosome 4 at 99,221,304 bp
  • T to A, chromosome 5 at 24,434,330 bp
  • A to G, chromosome 5 at 34,351,361 bp
  • T to G, chromosome 5 at 96,174,328 bp
  • T to C, chromosome 5 at 120,630,150 bp
  • T to C, chromosome 5 at 137,411,516 bp
  • T to C, chromosome 6 at 13,196,101 bp
  • T to C, chromosome 6 at 43,274,093 bp
  • G to A, chromosome 7 at 30,720,225 bp
  • A to T, chromosome 7 at 46,783,613 bp
  • A to G, chromosome 7 at 75,739,465 bp
  • C to T, chromosome 7 at 102,973,527 bp
  • A to G, chromosome 8 at 22,932,113 bp
  • C to A, chromosome 8 at 25,038,658 bp
  • A to G, chromosome 8 at 71,290,999 bp
  • A to G, chromosome 8 at 110,222,252 bp
  • A to G, chromosome 9 at 4,427,074 bp
  • C to G, chromosome 9 at 21,290,889 bp
  • A to G, chromosome 9 at 65,587,776 bp
  • A to G, chromosome 9 at 91,379,262 bp
  • A to T, chromosome 10 at 23,116,668 bp
  • G to A, chromosome 10 at 75,044,496 bp
  • A to T, chromosome 10 at 94,220,818 bp
  • A to T, chromosome 11 at 53,280,568 bp
  • A to G, chromosome 11 at 58,502,118 bp
  • G to A, chromosome 11 at 67,220,615 bp
  • A to G, chromosome 11 at 96,303,720 bp
  • G to A, chromosome 11 at 120,497,089 bp
  • C to T, chromosome 12 at 54,701,612 bp
  • T to A, chromosome 14 at 18,011,187 bp
  • T to C, chromosome 14 at 26,815,507 bp
  • T to A, chromosome 15 at 75,431,400 bp
  • T to C, chromosome 15 at 100,475,130 bp
  • T to A, chromosome 16 at 19,673,529 bp
  • A to G, chromosome 16 at 90,554,372 bp
  • G to A, chromosome 17 at 25,742,934 bp
  • A to T, chromosome 17 at 29,308,612 bp
  • C to A, chromosome 17 at 30,813,151 bp
  • A to G, chromosome 18 at 36,940,546 bp
  • T to A, chromosome 18 at 61,697,868 bp
  • T to C, chromosome 19 at 5,716,293 bp
  • T to A, chromosome Y at 1,394,078 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4457 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
041717-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.