Strain Name:
C57BL/6J-MtgxR4599Btlr/Mmmh
Stock Number:
041815-MU
Citation ID:
RRID:MMRRC_041815-MU
Other Names:
R4599 (G1), C57BL/6J-MtgxR4599Btlr
Major Collection:

Gene Information

Cdk4
Name: cyclin-dependent kinase 4
Synonyms: p34PSK-J3/cdk4, Crk3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 12567
HGNC: HGNC:1773
Homologene: 55429
Sema6d
Name: sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
Synonyms: Sema6D-5, Sema6D-2, Sema6D-4, 1110067B02Rik, Sema6D-1, Sema6D-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 214968
Homologene: 16195
Chrna7
Name: cholinergic receptor, nicotinic, alpha polypeptide 7
Synonyms: alpha7 nicotinic receptor, Acra7, alpha7-nAChR, alpha7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 11441
HGNC: HGNC:1960
Homologene: 593
Pik3cb
Name: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
Synonyms: 1110001J02Rik, p110beta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 74769
HGNC: HGNC:8976
Homologene: 21250
Nrxn2
Name: neurexin II
Synonyms: neurexin II alpha, neurexin II beta, 6430591O13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 18190
HGNC: HGNC:8009
Homologene: 86984
Tns3
Name: tensin 3
Synonyms: F830010I22Rik, TEM6, Tens1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 319939
Homologene: 49713
Dclre1c
Name: DNA cross-link repair 1C
Synonyms: Art, 9930121L06Rik, Artemis
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227525
Homologene: 32547
Plxnd1
Name: plexin D1
Synonyms: b2b553Clo, b2b1863Clo, 6230425C21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 67784
HGNC: HGNC:9107
Homologene: 22866
Gart
Name: phosphoribosylglycinamide formyltransferase
Synonyms: Gaps, Prgs
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 14450
HGNC: HGNC:4163
Homologene: 637
Ndc80
Name: NDC80 kinetochore complex component
Synonyms: Kntc2, HEC1, 2610020P18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 67052
VEGA: 17
Homologene: 38141
Prmt7
Name: protein arginine N-methyltransferase 7
Synonyms: 4933402B05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 214572
Homologene: 10382
Msh2
Name: mutS homolog 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 17685
HGNC: HGNC:7325
Homologene: 210
Pspc1
Name: paraspeckle protein 1
Synonyms: PSP1, 5730470C09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 66645
Homologene: 10108
Med27
Name: mediator complex subunit 27
Synonyms: Crsp8, D2Ertd434e, 2310042P07Rik, 1500015J03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 68975
HGNC: HGNC:2377
Homologene: 3152
Ints12
Name: integrator complex subunit 12
Synonyms: A230056J18Rik, 2810027J24Rik, Phf22, 1110020M19Rik, 4930529N21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 71793
Homologene: 32474
Ccdc34
Name: coiled-coil domain containing 34
Synonyms: 2810027O19Rik, 4930522P10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 68201
Homologene: 12245
Clock
Name: circadian locomotor output cycles kaput
Synonyms: bHLHe8, 5330400M04Rik, KAT13D
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 12753
HGNC: HGNC:2082
Homologene: 3603
Dab1
Name: disabled 1
Synonyms: C630028C02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 13131
HGNC: HGNC:2661
Homologene: 32084
Galnt4
Name: polypeptide N-acetylgalactosaminyltransferase 4
Synonyms: ppGaNTase-T4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 14426
HGNC: HGNC:4126
Homologene: 74511
Zp3
Name: zona pellucida glycoprotein 3
Synonyms: Zp-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 22788
Homologene: 5178
Pfas
Name: phosphoribosylformylglycinamidine synthase (FGAR amidotransferase)
Synonyms: 4432409B16Rik, Sofa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237823
HGNC: HGNC:8863
Homologene: 5970
Ror1
Name: receptor tyrosine kinase-like orphan receptor 1
Synonyms: 2810404D04Rik, Ntrkr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 26563
Homologene: 3675
Apc
Name: APC, WNT signaling pathway regulator
Synonyms: adenomatosis polyposis coli, Min, CC1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 11789
HGNC: HGNC:583
Homologene: 30950
Rsu1
Name: Ras suppressor protein 1
Synonyms: RsuI, rsp-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20163
Homologene: 7521
Gcnt2
Name: glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
Synonyms: IGnT, IGnTC, IGnTB, IGnTA, 5330430K10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 14538
VEGA: 13
HGNC: HGNC:4204
Homologene: 41535
Dapk1
Name: death associated protein kinase 1
Synonyms: DAP-Kinase, 2810425C21Rik, 2310039H24Rik, D13Ucla1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 69635
VEGA: 13
HGNC: HGNC:2674
Homologene: 3626
Stard3nl
Name: STARD3 N-terminal like
Synonyms: 6530409L22Rik, 0610035N01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 76205
Homologene: 11501
Ttc7b
Name: tetratricopeptide repeat domain 7B
Synonyms: Ttc7l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 104718
VEGA: 12
Homologene: 14675
Spint1
Name: serine protease inhibitor, Kunitz type 1
Synonyms: HAI-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20732
Homologene: 9653
Tmem107
Name: transmembrane protein 107
Synonyms: 2810049P21Rik, 1110004B13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 66910
Homologene: 12052
Dock2
Name: dedicator of cyto-kinesis 2
Synonyms: CED-5, MBC, Hch
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 94176
HGNC: HGNC:2988
Homologene: 37984
Cd22
Name: CD22 antigen
Synonyms: Lyb-8, Lyb8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 12483
HGNC: HGNC:1643
Homologene: 31052
Rundc1
Name: RUN domain containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217201
Homologene: 15095
Pla2g4e
Name: phospholipase A2, group IVE
Synonyms: 2310026J01Rik, Pla2epsilon
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 329502
Homologene: 65339
Atp6v0a4
Name: ATPase, H+ transporting, lysosomal V0 subunit A4
Synonyms: Atp6n1b, V-ATPase alpha 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 140494
HGNC: HGNC:866
Homologene: 39904
Tns2
Name: tensin 2
Synonyms: nph, Tenc1, nep
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 209039
VEGA: 15
Homologene: 37077
Col5a3
Name: collagen, type V, alpha 3
Synonyms: Pro-alpha3(V)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 53867
Homologene: 9253
Ush2a
Name: usherin
Synonyms: MUSH2A, LOC381317, Ushrn, A930011D15Rik, LOC269160, A930037M10Rik, Ush2a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 22283
Homologene: 66151
Krt35
Name: keratin 35
Synonyms: Ha5, Krt1-24
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 53617
HGNC: HGNC:6453
Homologene: 1715
Clspn
Name: claspin
Synonyms: C85083, E130314M08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 269582
Homologene: 11138
D430041D05Rik
Name: RIKEN cDNA D430041D05 gene
Synonyms: G2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241589
Homologene: 115928
Tcp10a
Name: t-complex protein 10a
Synonyms: D17Leh66aa, Gm10326, D17Leh66A, Tcp-10a, T66A-a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 21461
Homologene: 83254
Dpp6
Name: dipeptidylpeptidase 6
Synonyms: LOC384168, Peplb, Dpp-6, B930011P16Rik, In(5)6H-p, Rw
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 13483
HGNC: HGNC:3010
Homologene: 22560
Tie1
Name: tyrosine kinase with immunoglobulin-like and EGF-like domains 1
Synonyms: tie-1, D430008P04Rik, TIE
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 21846
Homologene: 3957
Myo1c
Name: myosin IC
Synonyms: myr2, mm1beta, myosin-Ibeta, C80397
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 17913
HGNC: HGNC:7597
Homologene: 32046
Tnfrsf18
Name: tumor necrosis factor receptor superfamily, member 18
Synonyms: Gitr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 21936
Homologene: 48270
Myo1a
Name: myosin IA
Synonyms: Myhl, BBM-I, brush border myosin 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 432516
VEGA: 10
HGNC: HGNC:7595
Homologene: 21113
Csmd2
Name: CUB and Sushi multiple domains 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 329942
Homologene: 89034
Abca14
Name: ATP-binding cassette, sub-family A (ABC1), member 14
Synonyms: 1700110B15Rik, 4930539G24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 67928
Homologene: 86128
Vmn2r13
Name: vomeronasal 2, receptor 13
Synonyms: Gm4867
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231589
Homologene: 129606
Clta
Name: clathrin, light polypeptide (Lca)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 12757
HGNC: HGNC:2090
Homologene: 1384
Kif26b
Name: kinesin family member 26B
Synonyms: N-11 kinesin, D230039L06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 269152
Homologene: 18623
Rilp
Name: Rab interacting lysosomal protein
Synonyms: LOC333615
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 280408
Homologene: 19596
Olfr1380
Name: olfactory receptor 1380
Synonyms: GA_x6K02T2QP88-5871967-5871032, MOR256-66_i
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 404336
Homologene: 72463
Herc6
Name: hect domain and RLD 6
Synonyms: Herc5, CEB1, 2510038N07Rik, 4930427L17Rik, 1700121D12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 67138
Homologene: 70768
Laptm5
Name: lysosomal-associated protein transmembrane 5
Synonyms: E3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 16792
Homologene: 4922
Dyrk1b
Name: dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
Synonyms: Mirk
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 13549
HGNC: HGNC:3092
Homologene: 31253
Ankrd13b
Name: ankyrin repeat domain 13b
Synonyms: B930093C12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 268445
Homologene: 27367
Cab39
Name: calcium binding protein 39
Synonyms: 39kDa, MO25alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12283
Homologene: 69212
Tspoap1
Name: TSPO associated protein 1
Synonyms: peripheral, Bzrap1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 207777
Homologene: 37961
Psme3
Name: proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)
Synonyms: REGgamma, pa28g, PA28gamma, Ki
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 19192
HGNC: HGNC:9570
Homologene: 2111
Slc5a11
Name: solute carrier family 5 (sodium/glucose cotransporter), member 11
Synonyms: Kst1, 2010013B02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233836
Homologene: 14184
Padi3
Name: peptidyl arginine deiminase, type III
Synonyms: PAD type III, Pad3, Pdi3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 18601
Homologene: 7882
Myrip
Name: myosin VIIA and Rab interacting protein
Synonyms: A230081N12Rik, Slac2-c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 245049
Homologene: 9150
Coq6
Name: coenzyme Q6 monooxygenase
Synonyms: 5930427M12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 217707
Homologene: 6039
Irx1
Name: Iroquois homeobox 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 16371
Homologene: 19065
Apold1
Name: apolipoprotein L domain containing 1
Synonyms: LOC381823
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 381823
Homologene: 12781
Fam166b
Name: family with sequence similarity 166, member B
Synonyms: 4833436C18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 329831
Homologene: 52229
Mterf3
Name: mitochondrial transcription termination factor 3
Synonyms: 2410017I18Rik, Mterfd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 66410
Homologene: 9310
1700001J03Rik
Name: RIKEN cDNA 1700001J03 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 69282
Homologene: 86127
Tlr12
Name: toll-like receptor 12
Synonyms: LOC384059, Tlr11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 384059
Homologene: 135964
Olfr676
Name: olfactory receptor 676
Synonyms: GA_x6K02T2PBJ9-7664016-7664969, MOR32-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259099
Homologene: 64955
Lin7a
Name: lin-7 homolog A (C. elegans)
Synonyms: TIP-33, LIN-7A, MALS-1, Veli
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 108030
VEGA: 10
Homologene: 20976
Pdrg1
Name: p53 and DNA damage regulated 1
Synonyms: 1110004D19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 68559
Homologene: 12779
Epor
Name: erythropoietin receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 13857
VEGA: 9
HGNC: HGNC:3416
Homologene: 95
Pcdhgb1
Name: protocadherin gamma subfamily B, 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93699
HGNC: HGNC:8708
Homologene: 81867
Gale
Name: galactose-4-epimerase, UDP
Synonyms: 2310002A12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 74246
HGNC: HGNC:4116
Homologene: 347
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 85,848,329 bp
  • A to G, chromosome 1 at 178,530,459 bp
  • A to G, chromosome 1 at 188,911,647 bp
  • T to A, chromosome 2 at 3,433,761 bp
  • T to C, chromosome 2 at 13,170,004 bp
  • A to G, chromosome 2 at 29,524,458 bp
  • A to T, chromosome 2 at 104,208,183 bp
  • A to T, chromosome 2 at 110,044,448 bp
  • T to C, chromosome 2 at 119,246,460 bp
  • T to G, chromosome 2 at 120,186,382 bp
  • T to A, chromosome 2 at 124,654,231 bp
  • T to C, chromosome 2 at 153,012,390 bp
  • T to A, chromosome 3 at 133,098,453 bp
  • T to C, chromosome 4 at 43,427,574 bp
  • C to T, chromosome 4 at 44,012,819 bp
  • A to G, chromosome 4 at 100,407,910 bp
  • C to A, chromosome 4 at 104,704,220 bp
  • A to G, chromosome 4 at 118,472,634 bp
  • A to G, chromosome 4 at 126,581,460 bp
  • G to T, chromosome 4 at 127,988,128 bp
  • T to C, chromosome 4 at 128,617,332 bp
  • G to T, chromosome 4 at 130,916,005 bp
  • C to A, chromosome 4 at 135,967,837 bp
  • T to C, chromosome 4 at 140,798,111 bp
  • T to A, chromosome 4 at 156,028,788 bp
  • G to T, chromosome 5 at 27,634,548 bp
  • T to C, chromosome 5 at 76,235,810 bp
  • A to T, chromosome 5 at 109,156,456 bp
  • A to T, chromosome 5 at 135,984,235 bp
  • G to A, chromosome 5 at 146,184,229 bp
  • T to C, chromosome 6 at 38,078,802 bp
  • A to G, chromosome 6 at 57,659,713 bp
  • A to T, chromosome 6 at 115,994,276 bp
  • A to G, chromosome 6 at 134,984,069 bp
  • T to C, chromosome 7 at 28,182,431 bp
  • T to A, chromosome 7 at 30,875,900 bp
  • A to G, chromosome 7 at 63,103,790 bp
  • A to G, chromosome 7 at 105,036,073 bp
  • T to C, chromosome 7 at 120,255,403 bp
  • A to G, chromosome 7 at 123,258,378 bp
  • A to G, chromosome 8 at 106,250,329 bp
  • A to G, chromosome 9 at 20,774,559 bp
  • A to G, chromosome 9 at 21,961,859 bp
  • C to T, chromosome 9 at 99,061,764 bp
  • A to G, chromosome 9 at 120,464,784 bp
  • T to A, chromosome 10 at 99,109,493 bp
  • T to C, chromosome 10 at 107,412,166 bp
  • T to C, chromosome 10 at 127,064,846 bp
  • A to T, chromosome 10 at 127,720,151 bp
  • T to C, chromosome 11 at 8,531,747 bp
  • T to A, chromosome 11 at 34,239,536 bp
  • T to C, chromosome 11 at 49,564,718 bp
  • T to C, chromosome 11 at 68,991,069 bp
  • T to A, chromosome 11 at 69,071,448 bp
  • T to C, chromosome 11 at 75,512,760 bp
  • T to C, chromosome 11 at 75,668,193 bp
  • T to C, chromosome 11 at 77,471,668 bp
  • C to T, chromosome 11 at 87,779,521 bp
  • T to C, chromosome 11 at 100,094,008 bp
  • T to C, chromosome 11 at 101,319,527 bp
  • A to G, chromosome 11 at 101,433,926 bp
  • T to C, chromosome 12 at 84,362,139 bp
  • G to A, chromosome 12 at 100,500,117 bp
  • A to G, chromosome 13 at 19,367,753 bp
  • G to T, chromosome 13 at 40,887,490 bp
  • C to T, chromosome 13 at 60,718,047 bp
  • A to G, chromosome 13 at 66,929,910 bp
  • C to A, chromosome 13 at 71,960,113 bp
  • A to C, chromosome 14 at 56,777,789 bp
  • C to T, chromosome 15 at 102,108,934 bp
  • A to T, chromosome 16 at 91,622,945 bp
  • A to C, chromosome 17 at 7,336,924 bp
  • T to C, chromosome 17 at 71,521,068 bp
  • A to G, chromosome 17 at 87,708,578 bp
  • T to A, chromosome 18 at 34,317,987 bp
  • A to T, chromosome 18 at 37,681,557 bp
  • A to G, chromosome 19 at 6,455,252 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4599 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
041815-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.