Strain Name:
C57BL/6J-MtgxR4655Btlr/Mmmh
Stock Number:
041915-MU
Citation ID:
RRID:MMRRC_041915-MU
Other Names:
R4655 (G1), C57BL/6J-MtgxR4655Btlr
Major Collection:

Strain Information

Slc12a6
Name: solute carrier family 12, member 6
Synonyms: KCC3, gaxp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 107723
Homologene: 21069
Eno2
Name: enolase 2, gamma neuronal
Synonyms: Eno-2, D6Ertd375e, NSE
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 13807
HGNC: HGNC:3353
Homologene: 74414
Rasgrp2
Name: RAS, guanyl releasing protein 2
Synonyms: CalDAG-GEFI, Caldaggef1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 19395
HGNC: HGNC:9879
Homologene: 4250
Npl
Name: N-acetylneuraminate pyruvate lyase
Synonyms: 0610033B02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 74091
Homologene: 12533
Srsf11
Name: serine and arginine-rich splicing factor 11
Synonyms: 0610009J05Rik, 2610019N13Rik, Sfrs11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 69207
Homologene: 36164
Tle1
Name: transducin-like enhancer of split 1
Synonyms: Grg1, Estm14, C230057C06Rik, Tle4l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 21885
Homologene: 21058
Akap9
Name: A kinase (PRKA) anchor protein (yotiao) 9
Synonyms: AKAP450, 5730481H23Rik, G1-448-15, repro12, mei2-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100986
HGNC: HGNC:379
Homologene: 134583
Prrc2a
Name: proline-rich coiled-coil 2A
Synonyms: G2, Bat-2, D17H6S51E, Wbp12, 3110039B05Rik, Bat2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 53761
Homologene: 10567
Itpr1
Name: inositol 1,4,5-trisphosphate receptor 1
Synonyms: P400, IP3R1, Pcp-1, Itpr-1, Ip3r, opt, InsP3R type I, Pcp1, wblo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 16438
HGNC: HGNC:6180
Homologene: 1673
Sfxn1
Name: sideroflexin 1
Synonyms: 2810002O05Rik, A930015P12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 14057
VEGA: 13
Homologene: 41494
Cyb5r4
Name: cytochrome b5 reductase 4
Synonyms: B5+B5R, b5/b5r, 2810034J18Rik, Ncb5or
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 266690
Homologene: 69207
Pus10
Name: pseudouridylate synthase 10
Synonyms: 2810013G11Rik, 4933435A13Rik, Ccdc139
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 74467
Homologene: 12566
Vps13b
Name: vacuolar protein sorting 13B
Synonyms: 1810042B05Rik, Coh1, C330002D13Rik, 2310042E16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 666173
VEGA: 15
HGNC: HGNC:2183
Homologene: 49516
Cux2
Name: cut-like homeobox 2
Synonyms: Cux-2, Cux2, ENSMUSG00000072641, Cutl2, 1700051K22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 13048
Homologene: 22426
Htt
Name: huntingtin
Synonyms: huntingtin, HD, htt, IT15, C430023I11Rik, Hdh
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 15194
HGNC: HGNC:4851
Homologene: 1593
Mtr
Name: 5-methyltetrahydrofolate-homocysteine methyltransferase
Synonyms: methionine synthase, MS, D830038K18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 238505
VEGA: 13
HGNC: HGNC:7468
Homologene: 37280
Psmd4
Name: proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
Synonyms: Mcb1, multiubiquitin-chain-binding protein, Af1, angiocidin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 19185
HGNC: HGNC:9561
Homologene: 55691
Acsl3
Name: acyl-CoA synthetase long-chain family member 3
Synonyms: 2610510B12Rik, C85929, Facl3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 74205
HGNC: HGNC:3570
Homologene: 3278
Tpcn1
Name: two pore channel 1
Synonyms: 5730403B01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 252972
Homologene: 9905
Tmprss4
Name: transmembrane protease, serine 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 214523
Homologene: 80930
Flt3
Name: FMS-like tyrosine kinase 3
Synonyms: CD135, Flk-2, Flt-3, Flk2, wmfl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 14255
HGNC: HGNC:3765
Homologene: 3040
Ucp3
Name: uncoupling protein 3 (mitochondrial, proton carrier)
Synonyms: UCP-3, Slc25a9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 22229
Homologene: 2517
Itga2
Name: integrin alpha 2
Synonyms: VLA-2 receptor, alpha 2 subunit, CD49B, DX5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 16398
VEGA: 13
HGNC: HGNC:6137
Homologene: 1662
Pclo
Name: piccolo (presynaptic cytomatrix protein)
Synonyms: Acz, Pico
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 26875
Homologene: 69111
Mmp9
Name: matrix metallopeptidase 9
Synonyms: gelatinase B, Gel B, B/MMP9, MMP-9, Clg4b, Gelatinase B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 17395
HGNC: HGNC:7176
Homologene: 3659
Abca4
Name: ATP-binding cassette, sub-family A (ABC1), member 4
Synonyms: Rim protein, RmP, Abc10, D430003I15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 11304
HGNC: HGNC:34
Homologene: 298
Or8b1c
Name: olfactory receptor family 8 subfamily B member 1C
Synonyms: GA_x6K02T2PVTD-32165709-32166641, MOR167-1, Olfr905
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258800
VEGA: 9
Homologene: 110524
Unc80
Name: unc-80, NALCN activator
Synonyms: C230061B10Rik, C030018G13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 329178
Homologene: 122243
Tppp
Name: tubulin polymerization promoting protein
Synonyms: 2900041A09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 72948
Homologene: 21389
Neb
Name: nebulin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 17996
HGNC: HGNC:7720
Homologene: 136285
Fbxo30
Name: F-box protein 30
Synonyms: 1700026A16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 71865
Homologene: 12959
Wdfy4
Name: WD repeat and FYVE domain containing 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 545030
Homologene: 83473
Pfdn6
Name: prefoldin subunit 6
Synonyms: Ke-2, H-2Ke2, H2-Ke2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 14976
HGNC: HGNC:4926
Homologene: 40720
Pus3
Name: pseudouridine synthase 3
Synonyms: 2610020J05Rik, 5730412F04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 67049
Homologene: 11339
Rab44
Name: RAB44, member RAS oncogene family
Synonyms: 9830134C10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 442827
Homologene: 53300
Dnah9
Name: dynein, axonemal, heavy chain 9
Synonyms: D11Ertd686e, Dnahc9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237806
HGNC: HGNC:2953
Homologene: 20357
Ephb3
Name: Eph receptor B3
Synonyms: Sek4, MDK5, HEK2, Etk2, Tyro6, Cek10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 13845
HGNC: HGNC:3394
Homologene: 20938
Eml1
Name: echinoderm microtubule associated protein like 1
Synonyms: ELP79, 1110008N23Rik, A930030P13Rik, heco
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 68519
HGNC: HGNC:3330
Homologene: 20931
Pilra
Name: paired immunoglobin-like type 2 receptor alpha
Synonyms: FDF03
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231805
Homologene: 8387
Vmn2r26
Name: vomeronasal 2, receptor 26
Synonyms: V2r1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 56552
Homologene: 135915
Vmn1r69
Name: vomeronasal 1 receptor 69
Synonyms: V1re9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 252904
Homologene: 120153
Wnk2
Name: WNK lysine deficient protein kinase 2
Synonyms: ESTM15, 1810073P09Rik, X83337
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 75607
Homologene: 19155
Rhobtb2
Name: Rho-related BTB domain containing 2
Synonyms: Dbc2, E130206H14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 246710
VEGA: 14
Homologene: 22873
Fbxl13
Name: F-box and leucine-rich repeat protein 13
Synonyms: 4921539K22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 320118
Homologene: 27057
Gas2l2
Name: growth arrest-specific 2 like 2
Synonyms: OTTMUSG00000000934
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237891
Homologene: 16409
Dcaf10
Name: DDB1 and CUL4 associated factor 10
Synonyms: Wdr32
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242418
Homologene: 32581
Cgn
Name: cingulin
Synonyms: 6330408J11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 70737
Homologene: 41394
Ttc21a
Name: tetratricopeptide repeat domain 21A
Synonyms: 4921538N17Rik, Thm2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 74052
Homologene: 14728
Ahnak
Name: AHNAK nucleoprotein (desmoyokin)
Synonyms: DY6, 2310047C17Rik, 1110004P15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 66395
VEGA: 19
HGNC: HGNC:347
Homologene: 67425
Vmn2r84
Name: vomeronasal 2, receptor 84
Synonyms: EG625068
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 625068
Homologene: 129606
Aadacl4fm2
Name: AADACL4 family member 2
Synonyms: Gm13124
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 627085
Homologene: 135767
Myo15b
Name: myosin XVB
Synonyms: LOC217328, LOC380737, E330039G21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217328
Vmn2r53
Name: vomeronasal 2, receptor 53
Synonyms: EG637908
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 637908
Homologene: 104040
Vmn2r74
Name: vomeronasal 2, receptor 74
Synonyms: EG546980
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 546980
Homologene: 115466
Ccs
Name: copper chaperone for superoxide dismutase
Synonyms: CCS, Ccsd
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 12460
VEGA: 19
HGNC: HGNC:1613
Homologene: 3762
Krt42
Name: keratin 42
Synonyms: Ka22, K17n, ecat6, 2410039E07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 68239
Homologene: 107091
Tmc6
Name: transmembrane channel-like gene family 6
Synonyms: EVER1, D11Ertd204e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217353
Homologene: 5258
Hddc2
Name: HD domain containing 2
Synonyms: 2310057G13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 69692
Homologene: 5431
Dyrk1b
Name: dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
Synonyms: Mirk
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 13549
HGNC: HGNC:3092
Homologene: 31253
4921509C19Rik
Name: RIKEN cDNA 4921509C19 gene
Synonyms: LOC381389
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 381393
Homologene: 72396
Hkdc1
Name: hexokinase domain containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216019
Homologene: 128937
Ptger4
Name: prostaglandin E receptor 4 (subtype EP4)
Synonyms: Ptgerep4, EP4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 19219
HGNC: HGNC:9596
Homologene: 20261
Or8k3
Name: olfactory receptor family 8 subfamily K member 3
Synonyms: GA_x6K02T2Q125-47703682-47702723, MOR188-3, Olfr1047, Olfr1060, Gm13721, MOR190-5_p, MOR190-4P, GA_x6K02T2Q125-47867369-47866428, Olfr1060-ps1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 259014
Homologene: 133664
Gm10334
Name: predicted gene 10334
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 100040233
Homologene: 88408
Pdp2
Name: pyruvate dehydrogenase phosphatase catalytic subunit 2
Synonyms: LOC382051, 4833426J09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 382051
Homologene: 36388
Togaram1
Name: TOG array regulator of axonemal microtubules 1
Synonyms: A430041B07Rik, Fam179b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 328108
VEGA: 12
Homologene: 15025
Smyd4
Name: SET and MYND domain containing 4
Synonyms: G430029E23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 319822
Homologene: 35098
Or1af1
Name: olfactory receptor family 1 subfamily AF member 1
Synonyms: GA_x6K02T2NLDC-33902472-33903401, MOR138-5P, MOR138-6, Olfr366
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 236509
Homologene: 114744
Cdc14a
Name: CDC14 cell division cycle 14A
Synonyms: CDC14A2, CDC14a1, Cdc14, A830059A17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229776
HGNC: HGNC:1718
Homologene: 75343
Akr1c6
Name: aldo-keto reductase family 1, member C6
Synonyms: estradiol 17-beta-dehydrogenase (A-specific), 3alpha-HSD, Akr1c1, Hsd17b5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 83702
Homologene: 84695
Lyrm7
Name: LYR motif containing 7
Synonyms: 9330147L21Rik, 1700024C24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 75530
Homologene: 18762
Rpl31-ps20
Name: ribosomal protein L31, pseudogene 20
Synonyms: Gm6635
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 625917
Evx1
Name: even-skipped homeobox 1
Synonyms: Evx-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 14028
HGNC: HGNC:3506
Homologene: 1507
Tuba3a
Name: tubulin, alpha 3A
Synonyms: M[a]3, Tuba3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 22144
Homologene: 128229
H3c7
Name: H3 clustered histone 7
Synonyms: H3.2-221, Hist1h3f
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 260423
Homologene: 133885
Grifin
Name: galectin-related inter-fiber protein
Synonyms: E130101O17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 77998
HGNC: HGNC:4577
Homologene: 14293
Gm18856
Name: predicted gene, 18856
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 100417835
VEGA: 13
Gm7358
Name: predicted gene 7358
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 664831
Homologene: 133217
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to G, chromosome 1 at 66,671,662 bp
  • A to G, chromosome 1 at 78,690,346 bp
  • T to C, chromosome 1 at 153,515,406 bp
  • A to G, chromosome 2 at 37,219,873 bp
  • A to G, chromosome 2 at 52,227,299 bp
  • A to G, chromosome 2 at 86,228,693 bp
  • A to G, chromosome 2 at 112,357,766 bp
  • A to G, chromosome 2 at 151,472,858 bp
  • A to G, chromosome 2 at 164,951,202 bp
  • G to A, chromosome 3 at 94,779,249 bp
  • G to A, chromosome 3 at 95,036,739 bp
  • T to A, chromosome 3 at 116,328,487 bp
  • A to G, chromosome 3 at 122,147,498 bp
  • A to G, chromosome 3 at 158,023,335 bp
  • G to A, chromosome 4 at 45,372,769 bp
  • A to G, chromosome 4 at 72,145,344 bp
  • A to T, chromosome 4 at 144,555,075 bp
  • G to A, chromosome 5 at 4,046,403 bp
  • T to C, chromosome 5 at 14,682,383 bp
  • A to G, chromosome 5 at 21,582,039 bp
  • A to G, chromosome 5 at 34,906,132 bp
  • A to G, chromosome 5 at 120,539,257 bp
  • G to A, chromosome 5 at 121,885,934 bp
  • C to T, chromosome 5 at 137,835,326 bp
  • A to G, chromosome 5 at 140,564,545 bp
  • G to A, chromosome 5 at 147,349,593 bp
  • T to A, chromosome 6 at 41,446,050 bp
  • A to T, chromosome 6 at 52,314,197 bp
  • G to A, chromosome 6 at 108,481,293 bp
  • T to A, chromosome 6 at 124,061,416 bp
  • T to C, chromosome 6 at 124,763,926 bp
  • A to G, chromosome 6 at 125,281,167 bp
  • A to G, chromosome 7 at 10,580,099 bp
  • G to A, chromosome 7 at 12,582,005 bp
  • T to C, chromosome 7 at 28,185,751 bp
  • T to C, chromosome 7 at 85,961,347 bp
  • A to C, chromosome 7 at 100,480,524 bp
  • A to G, chromosome 8 at 104,594,536 bp
  • A to C, chromosome 9 at 35,564,932 bp
  • C to A, chromosome 9 at 38,472,824 bp
  • T to C, chromosome 9 at 45,176,404 bp
  • A to G, chromosome 9 at 87,059,429 bp
  • A to G, chromosome 9 at 119,961,762 bp
  • T to C, chromosome 10 at 11,291,093 bp
  • G to T, chromosome 10 at 31,328,020 bp
  • T to A, chromosome 10 at 62,400,463 bp
  • A to T, chromosome 10 at 130,394,104 bp
  • T to C, chromosome 11 at 23,672,707 bp
  • T to C, chromosome 11 at 54,848,608 bp
  • T to C, chromosome 11 at 65,955,732 bp
  • C to T, chromosome 11 at 75,390,732 bp
  • T to C, chromosome 11 at 83,423,175 bp
  • C to A, chromosome 11 at 100,269,845 bp
  • T to C, chromosome 11 at 115,890,697 bp
  • A to T, chromosome 11 at 117,773,042 bp
  • A to G, chromosome 12 at 64,967,120 bp
  • G to A, chromosome 12 at 108,534,713 bp
  • T to C, chromosome 13 at 4,449,429 bp
  • A to G, chromosome 13 at 12,227,793 bp
  • T to C, chromosome 13 at 13,965,647 bp
  • T to C, chromosome 13 at 23,544,753 bp
  • T to G, chromosome 13 at 49,056,883 bp
  • C to A, chromosome 13 at 54,092,438 bp
  • G to T, chromosome 13 at 74,030,864 bp
  • A to C, chromosome 13 at 114,873,269 bp
  • T to C, chromosome 14 at 32,989,936 bp
  • T to A, chromosome 14 at 69,795,989 bp
  • C to A, chromosome 15 at 5,243,064 bp
  • T to C, chromosome 15 at 35,770,689 bp
  • G to A, chromosome 16 at 21,222,208 bp
  • A to T, chromosome 17 at 14,059,148 bp
  • A to G, chromosome 17 at 29,139,194 bp
  • A to T, chromosome 17 at 33,940,040 bp
  • A to T, chromosome 17 at 35,155,614 bp
  • A to G, chromosome 19 at 4,839,204 bp
  • T to C, chromosome 19 at 6,404,846 bp
  • A to G, chromosome 19 at 9,008,701 bp
  • A to T, chromosome 19 at 30,160,702 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4655 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
041915-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.