Strain Name:
C57BL/6J-MtgxR4719Btlr/Mmmh
Stock Number:
041957-MU
Citation ID:
RRID:MMRRC_041957-MU
Other Names:
R4719 (G1), C57BL/6J-MtgxR4719Btlr
Major Collection:

Gene Information

Slc12a1
Name: solute carrier family 12, member 1
Synonyms: Nkcc2, mBSC1, D630042G03Rik, urehr3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20495
Homologene: 286
Lyst
Name: lysosomal trafficking regulator
Synonyms: D13Sfk13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 17101
VEGA: 13
HGNC: HGNC:1968
Homologene: 61
Dgat2
Name: diacylglycerol O-acyltransferase 2
Synonyms: 0610010B06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 67800
Homologene: 23580
Nudc
Name: nudC nuclear distribution protein
Synonyms: NudC, Silg92
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 18221
HGNC: HGNC:8045
Homologene: 4812
Lefty1
Name: left right determination factor 1
Synonyms: lefty-1, Stra3, Lefty, Ebaf
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 13590
HGNC: HGNC:6552
Homologene: 49231
Sash1
Name: SAM and SH3 domain containing 1
Synonyms: A330076K04Rik, 1100001C18Rik, 2500002E12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 70097
Homologene: 69182
Secisbp2
Name: SECIS binding protein 2
Synonyms: 2210413N07Rik, SBP2, 2810012K13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 75420
Homologene: 11415
Kmt2e
Name: lysine (K)-specific methyltransferase 2E
Synonyms: 1810033J14Rik, D230038D11Rik, 9530077A04Rik, Mll5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 69188
Homologene: 18822
Nfib
Name: nuclear factor I/B
Synonyms: 6720429L07Rik, E030026I10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 18028
HGNC: HGNC:7785
Homologene: 4087
Thbs3
Name: thrombospondin 3
Synonyms: Thbs-3, TSP3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 21827
Homologene: 5159
Dscaml1
Name: DS cell adhesion molecule like 1
Synonyms: 4930435C18Rik, 4921507G06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 114873
VEGA: 9
Homologene: 79549
Foxo3
Name: forkhead box O3
Synonyms: FKHRL1, Fkhr2, 2010203A17Rik, 1110048B16Rik, Foxo3a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 56484
HGNC: HGNC:3821
Homologene: 31039
Ints3
Name: integrator complex subunit 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229543
Homologene: 11309
Pcmtd1
Name: protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
Synonyms: 8430411F12Rik, A030012M09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 319263
Homologene: 14180
Senp1
Name: SUMO1/sentrin specific peptidase 1
Synonyms: 2310046A20Rik, E330036L07Rik, D15Ertd528e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223870
Homologene: 8731
Zfp141
Name: zinc finger protein 141
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 434178
Car9
Name: carbonic anhydrase 9
Synonyms: CAIX, MN/CA9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230099
HGNC: HGNC:1383
Homologene: 20325
Fcrl5
Name: Fc receptor-like 5
Synonyms: BXMAS1-like protein 2, Fcrh3, mBXMH2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 329693
Homologene: 137404
Havcr1
Name: hepatitis A virus cellular receptor 1
Synonyms: Tim1, TIM-1, KIM-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 171283
Homologene: 136301
Lrrn2
Name: leucine rich repeat protein 2, neuronal
Synonyms: NLRR-2, 5730406J09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 16980
Homologene: 21274
Zfp169
Name: zinc finger protein 169
Synonyms: 4930429A13Rik, 1700025J14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 67911
Homologene: 2572
Slc25a36
Name: solute carrier family 25, member 36
Synonyms: C330005L02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 192287
Homologene: 10039
Fancm
Name: Fanconi anemia, complementation group M
Synonyms: C730036B14Rik, D12Ertd364e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 104806
VEGA: 12
Homologene: 35378
Nbeal1
Name: neurobeachin like 1
Synonyms: A530050O19Rik, ALS2CR17, A530083I02Rik, 2310076G13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 269198
Homologene: 16453
Pigt
Name: phosphatidylinositol glycan anchor biosynthesis, class T
Synonyms: CGI-06, 4930534E15Rik, Ndap7, NDAP, 2510012P17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 78928
Homologene: 6134
Pomgnt1
Name: protein O-linked mannose beta 1,2-N-acetylglucosaminyltransferase
Synonyms: 0610016I07Rik, 4930467B06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 68273
Homologene: 9806
Limd2
Name: LIM domain containing 2
Synonyms: 0610025L06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 67803
Homologene: 12731
Srcap
Name: Snf2-related CREBBP activator protein
Synonyms: F630004O05Rik, B930091H02Rik, D030022P06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 100043597
Homologene: 38213
Fance
Name: Fanconi anemia, complementation group E
Synonyms: 2810451D06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 72775
HGNC: HGNC:3586
Homologene: 11066
Gpr152
Name: G protein-coupled receptor 152
Synonyms: LOC269053, A930009H15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 269053
VEGA: 19
Homologene: 35474
Muc5ac
Name: mucin 5, subtypes A and C, tracheobronchial/gastric
Synonyms: MGM, 2210005L13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 17833
HGNC: HGNC:7515
Homologene: 137237
Rnf213
Name: ring finger protein 213
Synonyms: D11Ertd759e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 672511
Homologene: 45439
Mcoln2
Name: mucolipin 2
Synonyms: 3300002C04Rik, mucolipidin 2, TRPML2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 68279
Homologene: 12258
Ncoa6
Name: nuclear receptor coactivator 6
Synonyms: PRIP, ASC2, RAP250, AIB3, NRC, ASC-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 56406
Homologene: 137337
Wdr17
Name: WD repeat domain 17
Synonyms: 3010002I12Rik, B230207L18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 244484
Homologene: 12460
Cngb3
Name: cyclic nucleotide gated channel beta 3
Synonyms: CNG6, CCNC2, Cngbeta2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 30952
HGNC: HGNC:2153
Homologene: 40908
Kcna10
Name: potassium voltage-gated channel, shaker-related subfamily, member 10
Synonyms: Kv1.8, Kcna8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 242151
HGNC: HGNC:6219
Homologene: 4054
Abcb11
Name: ATP-binding cassette, sub-family B (MDR/TAP), member 11
Synonyms: PFIC2, ABC16, PGY4, Lith1, sister of P-glycoprotein, Bsep
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 27413
HGNC: HGNC:42
Homologene: 74509
Tnxb
Name: tenascin XB
Synonyms: Tnx, TN-MHC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 81877
Homologene: 49589
Mrps21
Name: mitochondrial ribosomal protein S21
Synonyms: 1810031B19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 66292
Homologene: 45365
Ptprn2
Name: protein tyrosine phosphatase, receptor type, N polypeptide 2
Synonyms: PTP-NP, IA-2 beta, phogrin, IA-2beta, 4930425H11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 19276
HGNC: HGNC:9677
Homologene: 2134
Hltf
Name: helicase-like transcription factor
Synonyms: P113, Snf2l3, Smarca3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 20585
Homologene: 30136
Col6a4
Name: collagen, type VI, alpha 4
Synonyms: EG235580, 1110001D15Rik, Dvwa, Vwa6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 68553
Homologene: 130754
Adamtsl4
Name: ADAMTS-like 4
Synonyms: Tsrc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229595
Homologene: 23141
Mdga2
Name: MAM domain containing glycosylphosphatidylinositol anchor 2
Synonyms: Mdga2, 9330209L04Rik, 6720489L24Rik, Mamdc1, Adp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 320772
Homologene: 45659
Cpne9
Name: copine family member IX
Synonyms: A730016F12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 211232
Homologene: 84686
Cdh20
Name: cadherin 20
Synonyms: Cdh7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 23836
HGNC: HGNC:1760
Homologene: 8015
Agbl2
Name: ATP/GTP binding protein-like 2
Synonyms: A430081C19Rik, Ccp2, Ccp2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 271813
Homologene: 11715
Gabbr2
Name: gamma-aminobutyric acid (GABA) B receptor, 2
Synonyms: Gababr2, LOC242425, Gpr51, GB2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242425
HGNC: HGNC:4507
Homologene: 55902
Arhgef40
Name: Rho guanine nucleotide exchange factor (GEF) 40
Synonyms: E130112L23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 268739
Homologene: 19560
Hdac10
Name: histone deacetylase 10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 170787
Homologene: 23749
Olfr643
Name: olfactory receptor 643
Synonyms: GA_x6K02T2PBJ9-6793628-6792684, MOR13-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259081
Homologene: 17491
Nostrin
Name: nitric oxide synthase trafficker
Synonyms: mDaIP2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 329416
Homologene: 43142
Tas2r131
Name: taste receptor, type 2, member 131
Synonyms: mGR31, Tas2r31, mt2r61, T2R31
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 387356
Homologene: 52298
Wnt10a
Name: wingless-type MMTV integration site family, member 10A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 22409
Homologene: 22525
Ces1g
Name: carboxylesterase 1G
Synonyms: Ses-1, Ces-1, Ces1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 12623
HGNC: HGNC:1863
Homologene: 137354
Sv2c
Name: synaptic vesicle glycoprotein 2c
Synonyms: 4930527L09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 75209
Homologene: 57152
Vmn1r43
Name: vomeronasal 1 receptor 43
Synonyms: V1ra5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 113847
Homologene: 130651
Atpsckmt
Name: ATP synthase C subunit lysine N-methyltransferase
Synonyms: A930016P21Rik, Fam173b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 68073
Homologene: 16780
Gm2128
Name: predicted gene 2128
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 100039269
Homologene: 45597
Mpp2
Name: membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
Synonyms: Dlg2, Dlgh2, Pals4, D11Bwg0652e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 50997
HGNC: HGNC:7220
Homologene: 3920
Mrgprb5
Name: MAS-related GPR, member B5
Synonyms: MrgB5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 404239
Homologene: 115575
Toporsl
Name: topoisomerase I binding, arginine/serine-rich like
Synonyms: 4930547C10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 68274
Homologene: 130753
Actr5
Name: ARP5 actin-related protein 5
Synonyms: B430109J19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 109275
Homologene: 6818
Art5
Name: ADP-ribosyltransferase 5
Synonyms: Yac-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 11875
Homologene: 7231
Faim2
Name: Fas apoptotic inhibitory molecule 2
Synonyms: NMP25, 2900002L20Rik, lifeguard, Lfg, Tmbim2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 72393
VEGA: 15
Homologene: 8192
Gatd1
Name: glutamine amidotransferase like class 1 domain containing 1
Synonyms: D230016J19Rik, Pddc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 213350
Homologene: 35234
Loxl4
Name: lysyl oxidase-like 4
Synonyms: 4833426I20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 67573
Homologene: 12977
Pramel6
Name: PRAME like 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 347711
Homologene: 77635
Ankdd1b
Name: ankyrin repeat and death domain containing 1B
Synonyms: 9330128J19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 271144
Homologene: 19566
Ifit3b
Name: interferon-induced protein with tetratricopeptide repeats 3B
Synonyms: I830012O16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 667370
HGNC: HGNC:5411
Homologene: 1189
Rasl10a
Name: RAS-like, family 10, member A
Synonyms: 2210403B10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 75668
Homologene: 4732
Rps4l-ps
Name: ribosomal protein S4-like, pseudogene
Synonyms: Gm6816
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 627967
RP23-211F21.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 7,155,101 bp
  • T to A, chromosome 1 at 60,235,563 bp
  • G to A, chromosome 1 at 74,803,603 bp
  • T to C, chromosome 1 at 104,934,310 bp
  • T to C, chromosome 1 at 132,939,177 bp
  • T to C, chromosome 1 at 136,118,652 bp
  • A to T, chromosome 1 at 180,937,712 bp
  • G to T, chromosome 2 at 69,144,812 bp
  • T to C, chromosome 2 at 69,259,627 bp
  • C to T, chromosome 2 at 87,510,752 bp
  • A to G, chromosome 2 at 90,815,389 bp
  • T to C, chromosome 2 at 125,153,993 bp
  • T to C, chromosome 2 at 155,391,161 bp
  • T to A, chromosome 2 at 158,626,513 bp
  • T to C, chromosome 2 at 164,501,624 bp
  • T to C, chromosome 3 at 20,064,701 bp
  • A to T, chromosome 3 at 87,444,189 bp
  • A to G, chromosome 3 at 89,216,840 bp
  • A to G, chromosome 3 at 90,415,521 bp
  • A to G, chromosome 3 at 95,679,586 bp
  • G to A, chromosome 3 at 95,862,797 bp
  • A to G, chromosome 3 at 107,194,901 bp
  • A to G, chromosome 3 at 146,175,713 bp
  • T to A, chromosome 4 at 19,309,562 bp
  • G to A, chromosome 4 at 43,508,616 bp
  • A to G, chromosome 4 at 46,718,797 bp
  • A to G, chromosome 4 at 52,611,996 bp
  • C to A, chromosome 4 at 82,504,730 bp
  • T to C, chromosome 4 at 116,155,775 bp
  • A to G, chromosome 4 at 133,533,265 bp
  • A to C, chromosome 5 at 23,492,315 bp
  • C to A, chromosome 6 at 89,869,855 bp
  • C to T, chromosome 6 at 113,302,060 bp
  • T to A, chromosome 6 at 132,956,973 bp
  • T to C, chromosome 7 at 41,157,932 bp
  • T to C, chromosome 7 at 42,476,687 bp
  • T to C, chromosome 7 at 48,168,778 bp
  • T to C, chromosome 7 at 99,158,297 bp
  • A to G, chromosome 7 at 102,098,494 bp
  • T to A, chromosome 7 at 104,058,733 bp
  • T to C, chromosome 7 at 114,927,302 bp
  • T to A, chromosome 7 at 127,541,559 bp
  • A to C, chromosome 7 at 141,411,068 bp
  • A to T, chromosome 7 at 141,789,763 bp
  • T to A, chromosome 8 at 54,639,876 bp
  • T to C, chromosome 8 at 93,317,090 bp
  • T to C, chromosome 9 at 45,672,695 bp
  • A to G, chromosome 9 at 97,090,119 bp
  • A to T, chromosome 9 at 106,068,252 bp
  • T to A, chromosome 10 at 8,729,713 bp
  • G to A, chromosome 10 at 42,197,778 bp
  • G to A, chromosome 11 at 5,058,517 bp
  • A to G, chromosome 11 at 46,752,441 bp
  • T to A, chromosome 11 at 102,064,433 bp
  • A to G, chromosome 11 at 106,158,788 bp
  • A to G, chromosome 11 at 119,420,067 bp
  • G to T, chromosome 12 at 65,121,706 bp
  • C to T, chromosome 12 at 66,471,001 bp
  • T to A, chromosome 12 at 116,824,396 bp
  • T to C, chromosome 13 at 13,650,350 bp
  • T to C, chromosome 13 at 48,490,158 bp
  • T to A, chromosome 13 at 51,652,732 bp
  • T to C, chromosome 13 at 95,986,811 bp
  • T to A, chromosome 13 at 96,417,747 bp
  • C to T, chromosome 14 at 52,004,938 bp
  • T to G, chromosome 15 at 31,608,097 bp
  • A to T, chromosome 15 at 89,126,221 bp
  • A to T, chromosome 15 at 98,056,850 bp
  • C to T, chromosome 15 at 99,527,579 bp
  • T to C, chromosome 17 at 28,318,319 bp
  • C to T, chromosome 17 at 34,689,420 bp
  • C to A, chromosome 19 at 4,143,224 bp
  • A to T, chromosome 19 at 34,612,630 bp
  • T to A, chromosome 19 at 42,607,591 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4719 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
041957-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.