Strain Name:
C57BL/6J-MtgxR4734Btlr/Mmmh
Stock Number:
041961-MU
Citation ID:
RRID:MMRRC_041961-MU
Other Names:
R4734 (G1), C57BL/6J-MtgxR4734Btlr
Major Collection:

Strain Information

Gpr37
Name: G protein-coupled receptor 37
Synonyms: parkin-associated endothelin B-like receptor, Pael-R
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 14763
HGNC: HGNC:4494
Homologene: 3875
Vps54
Name: VPS54 GARP complex subunit
Synonyms: 5330404P15Rik, Vps54l, wr, mSLP8
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 245944
Homologene: 5605
Mef2c
Name: myocyte enhancer factor 2C
Synonyms: 9930028G15Rik, 5430401D19Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 17260
HGNC: HGNC:6996
Homologene: 31087
Helb
Name: helicase (DNA) B
Synonyms: D10Ertd664e
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 117599
Homologene: 50463
Pcnt
Name: pericentrin (kendrin)
Synonyms: m275Asp, Pcnt2, m239Asp
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 18541
VEGA: 10
Trappc8
Name: trafficking protein particle complex 8
Synonyms: 5033403J15Rik, Trs85, D030074E01Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 75964
VEGA: 18
Homologene: 40993
Eif2ak4
Name: eukaryotic translation initiation factor 2 alpha kinase 4
Synonyms: GCN2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 27103
Homologene: 40891
Sdad1
Name: SDA1 domain containing 1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231452
Homologene: 6036
Mms19
Name: MMS19 cytosolic iron-sulfur assembly component
Synonyms: 2610042O15Rik, C86341, Mms19, Mms19l
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 72199
Homologene: 41480
Ccnt1
Name: cyclin T1
Synonyms: 2810478G24Rik, CycT1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 12455
HGNC: HGNC:1599
Homologene: 947
Impact
Name: impact, RWD domain protein
Synonyms: E430016J11Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 16210
VEGA: 18
Homologene: 5490
Eif2d
Name: eukaryotic translation initiation factor 2D
Synonyms: Lgtn, D1Ertd5e
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 16865
HGNC: HGNC:6583
Homologene: 38244
Ryr2
Name: ryanodine receptor 2, cardiac
Synonyms: 9330127I20Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 20191
VEGA: 13
Homologene: 37423
Supt6
Name: SPT6, histone chaperone and transcription elongation factor
Synonyms: SPT6, Supt6h, 5131400N11Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 20926
Homologene: 40661
Zc3h18
Name: zinc finger CCCH-type containing 18
Synonyms: 1190001B23Rik, 5830416A07Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 76014
Homologene: 44894
Htr2c
Name: 5-hydroxytryptamine (serotonin) receptor 2C
Synonyms: Htr1c, 5-HT2C receptor, 5-HT2cR, SR1, 5HT1c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 15560
HGNC: HGNC:5295
Homologene: 20242
Oit3
Name: oncoprotein induced transcript 3
Synonyms: EF-9
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 18302
Homologene: 7870
Dpf2
Name: double PHD fingers 2
Synonyms: ubi-d4, Req, 2210010M07Rik, requiem, Baf45d
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 19708
HGNC: HGNC:9964
Homologene: 21265
Kirrel1
Name: kirre like nephrin family adhesion molecule 1
Synonyms: Kirrel, Kirrel1, 6720469N11Rik, Neph1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 170643
Homologene: 10089
Pdia5
Name: protein disulfide isomerase associated 5
Synonyms: Pdir, 2700053F16Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 72599
VEGA: 16
Homologene: 4957
2700049A03Rik
Name: RIKEN cDNA 2700049A03 gene
Synonyms: Ta3, talpid3
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 76967
Homologene: 8839
Ccdc88a
Name: coiled coil domain containing 88A
Synonyms: GIV, C330012F17Rik, A430106J12Rik, D130005J21Rik, HkRP1, C130096N06Rik, Girdin
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 108686
Homologene: 41180
Gnl2
Name: guanine nucleotide binding protein nucleolar 2
Synonyms: Ngp-1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230737
Homologene: 6858
Piezo1
Name: piezo-type mechanosensitive ion channel component 1
Synonyms: Fam38a, Piezo1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234839
Homologene: 124356
Hectd4
Name: HECT domain E3 ubiquitin protein ligase 4
Synonyms: Gm15800
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 269700
Homologene: 28297
Slc29a3
Name: solute carrier family 29 (nucleoside transporters), member 3
Synonyms: Ent3, 4933435C21Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 71279
Homologene: 56805
Ddr2
Name: discoidin domain receptor family, member 2
Synonyms: Ntrkr3
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 18214
HGNC: HGNC:2731
Homologene: 68505
Ppil3
Name: peptidylprolyl isomerase (cyclophilin)-like 3
Synonyms: Cyp10l, 2510026K04Rik, 2310076N22Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 70225
HGNC: HGNC:9262
Homologene: 41717
Tfeb
Name: transcription factor EB
Synonyms: Tcfeb, bHLHe35, TFEB
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 21425
Homologene: 5182
Tspear
Name: thrombospondin type laminin G domain and EAR repeats
Synonyms: ORF65, C330046G03Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 252974
HGNC: HGNC:1268
Homologene: 36972
Dennd5b
Name: DENN domain containing 5B
Synonyms: 9330160C06Rik, D030011O10Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 320560
Homologene: 44911
Trim9
Name: tripartite motif-containing 9
Synonyms: C030048G07Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 94090
VEGA: 12
Homologene: 9045
Arap3
Name: ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
Synonyms: DRAG1, Centd3, E030006K04Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 106952
VEGA: 18
Homologene: 11199
Fat2
Name: FAT atypical cadherin 2
Synonyms: EMI2, mKIAA0811, LOC245827, Fath2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 245827
HGNC: HGNC:3596
Homologene: 1110
Chsy3
Name: chondroitin sulfate synthase 3
Synonyms: 4833446K15Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 78923
VEGA: 18
Homologene: 28624
Avl9
Name: AVL9 cell migration associated
Synonyms: D730049P16Rik, 5830411G16Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 78937
Homologene: 62425
Dnah9
Name: dynein, axonemal, heavy chain 9
Synonyms: Dnahc9, D11Ertd686e
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237806
HGNC: HGNC:2953
Homologene: 20357
Ryr3
Name: ryanodine receptor 3
Synonyms: calcium release channel isoform 3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 20192
Homologene: 68151
Scn5a
Name: sodium channel, voltage-gated, type V, alpha
Synonyms: Nav1.5, mH1, SkM2, Nav1.5c
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 20271
Homologene: 22738
Abcb11
Name: ATP-binding cassette, sub-family B member 11
Synonyms: ABC16, Lith1, PFIC2, sister of P-glycoprotein, Bsep, PGY4
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 27413
HGNC: HGNC:42
Homologene: 74509
Trpm5
Name: transient receptor potential cation channel, subfamily M, member 5
Synonyms: Ltrpc5, Mtr1, 9430099A16Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 56843
Homologene: 22818
Vmn2r102
Name: vomeronasal 2, receptor 102
Synonyms: EG224572
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224572
Homologene: 115024
Lnx2
Name: ligand of numb-protein X 2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 140887
Homologene: 17737
Dennd5a
Name: DENN domain containing 5A
Synonyms: 1500012B19Rik, ORF37, Rab6ip1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 19347
Homologene: 14584
Cfap96
Name: cilia and flagella associated protein 96
Synonyms: 1700029J07Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 69479
Homologene: 45977
Fscb
Name: fibrous sheath CABYR binding protein
Synonyms: EG623046
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 623046
VEGA: 12
Homologene: 136275
Myt1l
Name: myelin transcription factor 1-like
Synonyms: Pmng1, C630034G21Rik, 2900093J19Rik, Png-1, 2900046C06Rik, Nztf1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 17933
VEGA: 12
HGNC: HGNC:7623
Homologene: 7435
Vmn2r63
Name: vomeronasal 2, receptor 63
Synonyms: EG435975
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 435975
Homologene: 104832
Trmt1l
Name: tRNA methyltransferase 1 like
Synonyms: 1190005F20Rik, Trm1-like
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 98685
Homologene: 12801
Or5p51
Name: olfactory receptor family 5 subfamily P member 51
Synonyms: Olfr470, GA_x6K02T2PBJ9-10175273-10174329, MOR204-22
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258417
Shroom1
Name: shroom family member 1
Synonyms: Shrm1, Apx, 1300007L22Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 71774
Homologene: 12411
Lrrc19
Name: leucine rich repeat containing 19
Synonyms: 9130022A01Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 100061
Homologene: 36410
Thap12
Name: THAP domain containing 12
Synonyms: Dap4, Prkrir, 2900052B10Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 72981
HGNC: HGNC:9440
Homologene: 37952
Nuggc
Name: nuclear GTPase, germinal center associated
Synonyms: LOC239151, Gm600, SLIP-GC
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 100503545
Homologene: 72641
Cpb1
Name: carboxypeptidase B1
Synonyms: 1810063F02Rik, 0910001A18Rik, 2210008M23Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 76703
HGNC: HGNC:2299
Homologene: 68127
Usp20
Name: ubiquitin specific peptidase 20
Synonyms: Vdu2, 1700055M05Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 74270
Homologene: 4861
Cdhr18
Name: cadherin related family member 18
Synonyms: Gm281, LOC238939
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 238939
Homologene: 141164
Slc2a9
Name: solute carrier family 2 (facilitated glucose transporter), member 9
Synonyms: Glut9, SLC2a9A, SLC2A9B
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 117591
Homologene: 69290
Or5p1
Name: olfactory receptor family 5 subfamily P member 1
Synonyms: GA_x6K02T2PBJ9-10646917-10647849, MOR204-11, Olfr491
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258731
Homologene: 128150
Cyp2c65
Name: cytochrome P450, family 2, subfamily c, polypeptide 65
Synonyms: 2210009K14Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 72303
Homologene: 133566
Snx33
Name: sorting nexin 33
Synonyms: E130307J07Rik, Sh3px3
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235406
VEGA: 9
Homologene: 45165
Rassf8
Name: Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
Synonyms: 5133400D11Rik, mHoj-1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 71323
Homologene: 5219
Or4d1
Name: olfactory receptor family 4 subfamily D member 1
Synonyms: GA_x6K02T2PAEV-9555122-9554181, Olfr464, MOR240-2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 258407
HGNC: HGNC:8293
Homologene: 44975
Pdzrn4
Name: PDZ domain containing RING finger 4
Synonyms: 1110017D07Rik, LNX4, SAMCAP3L
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 239618
VEGA: 15
Homologene: 85433
Lrrcc1
Name: leucine rich repeat and coiled-coil domain containing 1
Synonyms: 4932441F23Rik, 1200008A14Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 71710
Homologene: 12559
Fhod3
Name: formin homology 2 domain containing 3
Synonyms: A930009H06Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 225288
VEGA: 18
Homologene: 45323
Zdhhc1
Name: zinc finger, DHHC domain containing 1
Synonyms: 4432412D04Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 70796
Homologene: 36891
Prb1c
Name: proline-rich protein BstNI subfamily 1C
Synonyms: Gm8882
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 667929
1700030K09Rik
Name: RIKEN cDNA 1700030K09 gene
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 72254
Homologene: 12975
Coro2b
Name: coronin, actin binding protein, 2B
Synonyms: E130012P22Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235431
HGNC: HGNC:2256
Homologene: 21228
Oog2
Name: oogenesin 2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 381570
Homologene: 77858
Gnpda2
Name: glucosamine-6-phosphate deaminase 2
Synonyms: Gnp2, 4921523I18Rik, 4933412A11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 67980
Homologene: 12381
Maml3
Name: mastermind like transcriptional coactivator 3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 433586
Homologene: 41284
2700062C07Rik
Name: RIKEN cDNA 2700062C07 gene
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 68046
VEGA: 18
Homologene: 12230
Glra1
Name: glycine receptor, alpha 1 subunit
Synonyms: B230397M16Rik, oscillator, nmf11, ot
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 14654
HGNC: HGNC:4326
Homologene: 20083
Or51f1
Name: olfactory receptor family 51 subfamily F member 1
Synonyms: Olfr566, MOR14-7P, GA_x6K02T2PBJ9-5560696-5559746
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258168
Homologene: 133721
G730003C15Rik
Name: RIKEN cDNA G730003C15 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Dcaf15
Name: DDB1 and CUL4 associated factor 15
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 212123
Homologene: 18182
Ttc9b
Name: tetratricopeptide repeat domain 9B
Synonyms: 2900074C18Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 73032
Homologene: 19938
Rpl31-ps17
Name: ribosomal protein L31, pseudogene 17
Synonyms: Gm16382
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 673582
Spata31d1b
Name: spermatogenesis associated 31 subfamily D, member 1B
Synonyms: Gm4934, Fam75d1b
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 238662
VEGA: 13
Gdpd2
Name: glycerophosphodiester phosphodiesterase domain containing 2
Synonyms: GDE3, 9130017L10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 71584
Homologene: 9792
Nphs1os
Name: nephrosis 1 homolog, nephrin, opposite strand
Synonyms: Nphs1as
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 445267
Btf3-ps5
Name: basic transcription factor 3, pseudogene 5
Synonyms: Gm5341
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 384719
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 58,431,269 bp
  • G to A, chromosome 1 at 59,120,190 bp
  • G to T, chromosome 1 at 131,165,152 bp
  • A to T, chromosome 1 at 151,442,637 bp
  • T to A, chromosome 1 at 169,998,088 bp
  • A to G, chromosome 2 at 31,019,824 bp
  • T to A, chromosome 2 at 69,323,962 bp
  • T to A, chromosome 2 at 112,910,502 bp
  • A to T, chromosome 2 at 118,422,087 bp
  • G to T, chromosome 3 at 14,562,285 bp
  • A to G, chromosome 3 at 20,263,712 bp
  • A to T, chromosome 3 at 51,689,875 bp
  • C to T, chromosome 3 at 87,089,151 bp
  • T to C, chromosome 4 at 94,638,349 bp
  • T to C, chromosome 4 at 125,041,018 bp
  • T to C, chromosome 4 at 144,196,451 bp
  • C to A, chromosome 5 at 38,382,099 bp
  • G to T, chromosome 5 at 69,577,368 bp
  • C to T, chromosome 5 at 92,304,977 bp
  • A to T, chromosome 5 at 121,341,977 bp
  • C to T, chromosome 5 at 147,029,137 bp
  • C to A, chromosome 6 at 25,689,086 bp
  • T to C, chromosome 6 at 56,736,494 bp
  • T to A, chromosome 6 at 132,361,928 bp
  • G to T, chromosome 6 at 145,815,540 bp
  • T to A, chromosome 6 at 149,019,412 bp
  • G to A, chromosome 7 at 27,656,018 bp
  • T to C, chromosome 7 at 30,463,498 bp
  • C to T, chromosome 7 at 42,928,120 bp
  • G to T, chromosome 7 at 90,107,807 bp
  • G to T, chromosome 7 at 98,715,954 bp
  • T to A, chromosome 7 at 98,715,955 bp
  • A to G, chromosome 7 at 102,856,979 bp
  • T to C, chromosome 7 at 107,845,428 bp
  • A to T, chromosome 7 at 108,317,752 bp
  • C to T, chromosome 7 at 109,896,336 bp
  • C to A, chromosome 7 at 143,082,785 bp
  • A to T, chromosome 8 at 45,970,417 bp
  • T to C, chromosome 8 at 72,458,635 bp
  • A to G, chromosome 8 at 84,097,728 bp
  • CGGGGG to CGGGGGG, chromosome 8 at 105,483,744 bp
  • A to T, chromosome 8 at 122,383,643 bp
  • G to T, chromosome 8 at 122,498,206 bp
  • T to A, chromosome 9 at 56,925,901 bp
  • T to C, chromosome 9 at 62,426,578 bp
  • T to C, chromosome 9 at 119,539,538 bp
  • A to T, chromosome 10 at 59,424,082 bp
  • A to G, chromosome 10 at 60,716,326 bp
  • T to C, chromosome 10 at 76,437,206 bp
  • C to T, chromosome 10 at 77,864,695 bp
  • T to C, chromosome 10 at 120,084,849 bp
  • A to T, chromosome 11 at 21,292,156 bp
  • A to G, chromosome 11 at 29,482,720 bp
  • C to T, chromosome 11 at 53,465,233 bp
  • A to G, chromosome 11 at 55,311,468 bp
  • C to A, chromosome 11 at 55,536,384 bp
  • G to A, chromosome 11 at 65,834,115 bp
  • T to C, chromosome 11 at 78,224,683 bp
  • T to A, chromosome 11 at 87,914,190 bp
  • T to C, chromosome 12 at 29,919,926 bp
  • A to G, chromosome 12 at 54,701,381 bp
  • T to C, chromosome 12 at 64,474,470 bp
  • T to C, chromosome 12 at 70,248,273 bp
  • T to A, chromosome 12 at 71,151,397 bp
  • T to C, chromosome 13 at 11,737,753 bp
  • G to A, chromosome 13 at 59,718,358 bp
  • T to A, chromosome 13 at 83,662,629 bp
  • T to C, chromosome 14 at 13,845,292 bp
  • T to C, chromosome 14 at 65,623,230 bp
  • A to T, chromosome 15 at 92,770,252 bp
  • G to A, chromosome 15 at 98,567,544 bp
  • A to T, chromosome 16 at 35,456,513 bp
  • T to A, chromosome 17 at 19,677,533 bp
  • T to C, chromosome 17 at 47,785,862 bp
  • T to A, chromosome 18 at 12,985,289 bp
  • G to A, chromosome 18 at 20,841,572 bp
  • A to G, chromosome 18 at 24,470,904 bp
  • T to A, chromosome 18 at 25,028,135 bp
  • A to G, chromosome 18 at 37,996,275 bp
  • C to A, chromosome 18 at 59,179,413 bp
  • A to G, chromosome 19 at 5,906,999 bp
  • A to G, chromosome 19 at 39,072,334 bp
  • T to A, chromosome 19 at 41,944,558 bp
  • G to A, chromosome X at 100,734,193 bp
  • A to G, chromosome X at 147,193,797 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4734 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
041961-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.