Strain Name:
C57BL/6J-MtgxR4736Btlr/Mmmh
Stock Number:
041963-MU
Citation ID:
RRID:MMRRC_041963-MU
Other Names:
R4736 (G1), C57BL/6J-MtgxR4736Btlr
Major Collection:

Strain Information

Ulk2
Name: unc-51 like kinase 2
Synonyms: Unc51.2, A830085I22Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 29869
Homologene: 5891
Tanc1
Name: tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
Synonyms: 1200003E16Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 66860
Homologene: 18946
Xrn1
Name: 5'-3' exoribonuclease 1
Synonyms: mXrn1, Dhm2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 24127
Homologene: 5894
Yes1
Name: YES proto-oncogene 1, Src family tyrosine kinase
Synonyms: Yes
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 22612
Homologene: 55900
Eif4g3
Name: eukaryotic translation initiation factor 4 gamma, 3
Synonyms: eIF4GII, 1500002J22Rik, 4930523M17Rik, G1-419-52, repro8
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230861
HGNC: HGNC:3298
Homologene: 2789
Ctage5
Name: CTAGE family, member 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Depdc5
Name: DEP domain containing 5
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 277854
Homologene: 34718
Agrn
Name: agrin
Synonyms: NMF380, Agrin, nmf380
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 11603
HGNC: HGNC:329
Homologene: 27907
Ezr
Name: ezrin
Synonyms: ezrin, p81, cytovillin, Vil2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 22350
Homologene: 55740
Taf4
Name: TATA-box binding protein associated factor 4
Synonyms: Taf2c1, TAFII135, TAFII130, Taf4a
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228980
Homologene: 55723
Med25
Name: mediator complex subunit 25
Synonyms: ESTM2, 2610529E18Rik, 2610034E13Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 75613
Homologene: 12614
Nol10
Name: nucleolar protein 10
Synonyms: LOC217431
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217431
VEGA: 12
Homologene: 5998
Xpo6
Name: exportin 6
Synonyms: Ranbp20, C230091E20Rik, 2610005L19Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 74204
Homologene: 12544
Esf1
Name: ESF1 nucleolar pre-rRNA processing protein homolog
Synonyms: 2610101J03Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 66580
Homologene: 5717
Myo9b
Name: myosin IXb
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 17925
HGNC: HGNC:7609
Homologene: 3058
Usp34
Name: ubiquitin specific peptidase 34
Synonyms: A530081C03Rik, Murr2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 17847
Homologene: 40978
Ap1g1
Name: adaptor protein complex AP-1, gamma 1 subunit
Synonyms: gamma-adaptin, Adtg, D8Ertd374e
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 11765
HGNC: HGNC:555
Homologene: 47995
Acin1
Name: apoptotic chromatin condensation inducer 1
Synonyms: 2610510L13Rik, 2610036I19Rik, Acinus
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 56215
Homologene: 22853
Ccdc167
Name: coiled-coil domain containing 167
Synonyms: 1110021J02Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 68597
Homologene: 79796
Scube2
Name: signal peptide, CUB domain, EGF-like 2
Synonyms: ICRFP703N2430Q5.1, ICRFP703B1614Q5.1, 4932442O19Rik, Cegf1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 56788
Homologene: 36383
Cdin1
Name: CDAN1 interacting nuclease 1
Synonyms: BC052040
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 399568
Homologene: 32780
Nktr
Name: natural killer tumor recognition sequence
Synonyms: D9Wsu172e, 5330401F18Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 18087
HGNC: HGNC:7833
Homologene: 122148
Tgfbr1
Name: transforming growth factor, beta receptor I
Synonyms: TbetaR-I, TbetaRI, ALK5, Alk-5
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 21812
Homologene: 3177
Dync2h1
Name: dynein cytoplasmic 2 heavy chain 1
Synonyms: DHC1b, DHC2, 4432416O06Rik, D330044F14Rik, D030010H02Rik, Dnchc2, b2b414Clo, m407Asp, m152Asp
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 110350
HGNC: HGNC:2962
Homologene: 14468
Emc3
Name: ER membrane protein complex subunit 3
Synonyms: 0610039A15Rik, Tmem111
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 66087
Homologene: 100707
Acbd5
Name: acyl-Coenzyme A binding domain containing 5
Synonyms: 1300014E15Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 74159
Homologene: 12541
Haus8
Name: 4HAUS augmin-like complex, subunit 8
Synonyms: 2410004L22Rik, Hice1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 76478
Homologene: 12644
Siglecg
Name: sialic acid binding Ig-like lectin G
Synonyms: mSiglec-G, A630096C01Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 243958
Homologene: 13228
Slc44a3
Name: solute carrier family 44, member 3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 213603
Homologene: 64830
Clec4a2
Name: C-type lectin domain family 4, member a2
Synonyms: dendritic cell immunoreceptor, DCIR, Clecsf6, Dcir1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 26888
Homologene: 49291
Mtcl2
Name: microtubule crosslinking factor 2
Synonyms: D430036N24Rik, 9830001H06Rik, Soga1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 320706
Homologene: 52382
Abcb6
Name: ATP-binding cassette, sub-family B member 6
Synonyms: 1200005B17Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 74104
HGNC: HGNC:47
Homologene: 11375
Skic2
Name: SKI2 subunit of superkiller complex
Synonyms: Ski2w, 4930534J06Rik, Skiv2l
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 108077
Homologene: 123971
Smad3
Name: SMAD family member 3
Synonyms: Smad 3, Madh3
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 17127
HGNC: HGNC:6769
Homologene: 55937
Trmt2a
Name: TRM2 tRNA methyltransferase 2A
Synonyms: Htf9c
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 15547
Homologene: 7374
Trpc6
Name: transient receptor potential cation channel, subfamily C, member 6
Synonyms: mtrp6, Trrp6
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 22068
VEGA: 9
Homologene: 37944
Itgae
Name: integrin alpha E, epithelial-associated
Synonyms: CD103, alpha-E1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 16407
HGNC: HGNC:6147
Homologene: 113560
Lama2
Name: laminin, alpha 2
Synonyms: merosin, mer
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 16773
HGNC: HGNC:6482
Homologene: 37306
Myo16
Name: myosin XVI
Synonyms: C230040D10Rik, Nyap3, BM140241
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244281
Homologene: 34710
Kif27
Name: kinesin family member 27
Synonyms: 4930517I18Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 75050
VEGA: 13
Homologene: 69235
Dennd6b
Name: DENN domain containing 6B
Synonyms: 1700027J05Rik, Fam116b
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 69440
VEGA: 15
Homologene: 57065
Pgm5
Name: phosphoglucomutase 5
Synonyms: 9530034F03Rik, aciculin
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 226041
HGNC: HGNC:8908
Homologene: 74881
Zfp990
Name: zinc finger protein 990
Synonyms: Gm13225
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 101056073
Unc80
Name: unc-80, NALCN activator
Synonyms: C230061B10Rik, C030018G13Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 329178
Homologene: 122243
Uba7
Name: ubiquitin-like modifier activating enzyme 7
Synonyms: 1300004C08Rik, Ube1l
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 74153
Homologene: 2502
Aadat
Name: aminoadipate aminotransferase
Synonyms: mKat-2, Kat2, KATII, Kyat2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 23923
Homologene: 56540
Nynrin
Name: NYN domain and retroviral integrase containing
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 277154
VEGA: 14
Homologene: 19483
Kcna10
Name: potassium voltage-gated channel, shaker-related subfamily, member 10
Synonyms: Kv1.8, Kcna8
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 242151
HGNC: HGNC:6219
Homologene: 4054
Ccr6
Name: C-C motif chemokine receptor 6
Synonyms: Cmkbr6
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 12458
VEGA: 17
HGNC: HGNC:1607
Homologene: 3214
Dbt
Name: dihydrolipoamide branched chain transacylase E2
Synonyms: BCKAD E2, D3Wsu60e, dihydrolipoyl transacylase, dihydrolipoyllysine-residue (2-methylpropanoyl)transferase
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 13171
HGNC: HGNC:2698
Homologene: 1444
1110002E22Rik
Name: RIKEN cDNA 1110002E22 gene
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 102634333
Homologene: 131709
Obscn
Name: obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Synonyms: LOC380698, OTTMUSG00000005786
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 380698
Homologene: 70869
Arhgap5
Name: Rho GTPase activating protein 5
Synonyms: p190-B, p190B
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 11855
VEGA: 12
HGNC: HGNC:675
Homologene: 907
Gbe1
Name: 1,4-alpha-glucan branching enzyme 1
Synonyms: 2310045H19Rik, 2810426P10Rik, D16Ertd536e
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 74185
HGNC: HGNC:4180
Homologene: 129
Or4c35
Name: olfactory receptor family 4 subfamily C member 35
Synonyms: GA_x6K02T2Q125-51409740-51410672, MOR232-2, Olfr1260
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258983
Homologene: 17455
Naip1
Name: NLR family, apoptosis inhibitory protein 1
Synonyms: D13Lsd1, Naip, Birc1a
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 17940
VEGA: 13
HGNC: HGNC:7634
Homologene: 113589
Dpp6
Name: dipeptidylpeptidase 6
Synonyms: Dpp-6, Peplb, In(5)6H-p, Rw, LOC384168, B930011P16Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 13483
HGNC: HGNC:3010
Homologene: 22560
Myom2
Name: myomesin 2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 17930
HGNC: HGNC:7614
Homologene: 2953
Serpina1f
Name: serine (or cysteine) peptidase inhibitor, clade A, member 1F
Synonyms: epserin, 0610012A11Rik, Serpina2
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 68348
HGNC: HGNC:8985
Homologene: 87037
Heca
Name: hdc homolog, cell cycle regulator
Synonyms: LOC380629
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 380629
VEGA: 10
Homologene: 32300
Mybpc2
Name: myosin binding protein C, fast-type
Synonyms: Fast-type C-protein
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233199
HGNC: HGNC:7550
Homologene: 3331
Nol4
Name: nucleolar protein 4
Synonyms: 4930568N03Rik, LOC383304, 1700013J13Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 319211
HGNC: HGNC:7870
Homologene: 36142
Unc5c
Name: unc-5 netrin receptor C
Synonyms: Unc5h3, B130051O18Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 22253
Homologene: 2765
Akr1d1
Name: aldo-keto reductase family 1, member D1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 208665
HGNC: HGNC:388
Homologene: 55943
Zfp759
Name: zinc finger protein 759
Synonyms: Rslcan-8
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 268670
VEGA: 13
Stt3a
Name: STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae)
Synonyms: Itm1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 16430
HGNC: HGNC:6172
Homologene: 40617
Hivep3
Name: human immunodeficiency virus type I enhancer binding protein 3
Synonyms: Krc, E030045D18Rik, 2900056N03Rik, Shn3, Schnurri-3
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 16656
Homologene: 7803
Ttll13
Name: tubulin tyrosine ligase-like family, member 13
Synonyms: 1700111A04Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 269954
Homologene: 136186
Cyth3
Name: cytohesin 3
Synonyms: cytohesin 3, Grp1, Pscd3
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 19159
HGNC: HGNC:9504
Homologene: 3116
Vmn1r71
Name: vomeronasal 1 receptor 71
Synonyms: V1re13
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 252910
Homologene: 74352
Hpdl
Name: 4-hydroxyphenylpyruvate dioxygenase-like
Synonyms: A830048M07Rik, Gloxd1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242642
Homologene: 13109
Haus6
Name: HAUS augmin-like complex, subunit 6
Synonyms: D4Ertd27e, 6230416J20Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230376
Homologene: 9760
Asic5
Name: acid-sensing ion channel family member 5
Synonyms: brain-liver-intestine amiloride-sensitive sodium channel, BLINaC, Accn5
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 58170
Homologene: 41171
Mdfic
Name: MyoD family inhibitor domain containing
Synonyms: clone 1.5, Kdt1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16543
Homologene: 18404
Arhgap45
Name: Rho GTPase activating protein 45
Synonyms: 6330406L22Rik, Hmha1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 70719
Homologene: 69120
Mrpl19
Name: mitochondrial ribosomal protein L19
Synonyms: MRP-L15, D6Ertd157e, Rpml15, RLX1, 9030416F12Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 56284
Homologene: 8851
Cabp5
Name: calcium binding protein 5
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 29865
Homologene: 8486
Aig1
Name: androgen-induced 1
Synonyms: CGI-103, 1500031O19Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 66253
Homologene: 32297
Slc22a13
Name: solute carrier family 22 (organic cation transporter), member 13
Synonyms: OCTL3, OCTL1, ORCTL3
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 102570
VEGA: 9
HGNC: HGNC:8494
Homologene: 3140
Rspo4
Name: R-spondin 4
Synonyms: A930029K19Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228770
Homologene: 65290
C4a
Name: complement C4A (Rodgers blood group)
Synonyms: Slp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 625018
Homologene: 36030
Josd2
Name: Josephin domain containing 2
Synonyms: 1110007C05Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 66124
Homologene: 26696
Or5g23
Name: olfactory receptor family 5 subfamily G member 23
Synonyms: GA_x6K02T2Q125-47087719-47086775, MOR175-9, Olfr1000
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 257899
Rpl36al
Name: ribosomal protein L36A-like
Synonyms: RPL36A, 2410038A03Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 66483
Homologene: 133572
Otub2
Name: OTU domain, ubiquitin aldehyde binding 2
Synonyms: 2010015L18Rik, OTU2, OTB2, 4930586I02Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 68149
Homologene: 57056
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 66,649,672 bp
  • A to T, chromosome 1 at 75,173,534 bp
  • G to T, chromosome 2 at 23,099,584 bp
  • G to A, chromosome 2 at 59,817,496 bp
  • T to C, chromosome 2 at 85,607,983 bp
  • C to T, chromosome 2 at 89,978,025 bp
  • A to G, chromosome 2 at 115,581,888 bp
  • T to A, chromosome 2 at 140,124,971 bp
  • T to C, chromosome 2 at 151,843,134 bp
  • T to A, chromosome 2 at 157,020,554 bp
  • A to T, chromosome 2 at 179,924,494 bp
  • C to T, chromosome 3 at 81,999,809 bp
  • C to A, chromosome 3 at 107,195,492 bp
  • T to C, chromosome 3 at 116,539,132 bp
  • A to G, chromosome 3 at 121,510,206 bp
  • T to C, chromosome 3 at 138,068,485 bp
  • A to T, chromosome 3 at 141,816,931 bp
  • A to G, chromosome 4 at 47,383,835 bp
  • A to G, chromosome 4 at 86,600,749 bp
  • T to C, chromosome 4 at 116,821,024 bp
  • A to G, chromosome 4 at 119,872,209 bp
  • T to A, chromosome 4 at 138,198,097 bp
  • A to T, chromosome 4 at 145,536,942 bp
  • G to A, chromosome 4 at 156,172,401 bp
  • A to G, chromosome 5 at 27,712,659 bp
  • A to T, chromosome 5 at 32,660,777 bp
  • A to G, chromosome 5 at 32,975,322 bp
  • G to A, chromosome 5 at 143,684,479 bp
  • A to G, chromosome 6 at 15,741,020 bp
  • T to C, chromosome 6 at 37,557,600 bp
  • A to T, chromosome 6 at 81,964,348 bp
  • G to A, chromosome 6 at 113,531,349 bp
  • T to C, chromosome 6 at 123,140,663 bp
  • A to T, chromosome 7 at 10,747,864 bp
  • A to G, chromosome 7 at 13,400,739 bp
  • T to C, chromosome 7 at 43,417,908 bp
  • G to A, chromosome 7 at 44,468,982 bp
  • T to C, chromosome 7 at 44,512,547 bp
  • G to A, chromosome 7 at 44,892,288 bp
  • T to A, chromosome 7 at 80,248,276 bp
  • A to G, chromosome 7 at 109,831,205 bp
  • T to C, chromosome 7 at 126,140,583 bp
  • G to T, chromosome 8 at 10,373,527 bp
  • T to A, chromosome 8 at 15,081,271 bp
  • T to C, chromosome 8 at 60,540,106 bp
  • C to T, chromosome 8 at 71,257,414 bp
  • T to C, chromosome 8 at 71,356,592 bp
  • G to A, chromosome 8 at 109,855,082 bp
  • A to T, chromosome 9 at 7,006,862 bp
  • T to C, chromosome 9 at 8,609,870 bp
  • T to A, chromosome 9 at 36,749,712 bp
  • T to G, chromosome 9 at 63,757,560 bp
  • G to T, chromosome 9 at 96,033,636 bp
  • T to C, chromosome 9 at 107,980,165 bp
  • T to C, chromosome 9 at 119,193,632 bp
  • T to A, chromosome 9 at 121,749,739 bp
  • C to A, chromosome 10 at 13,801,930 bp
  • G to A, chromosome 10 at 17,915,187 bp
  • T to C, chromosome 10 at 27,204,929 bp
  • A to G, chromosome 10 at 80,026,172 bp
  • T to A, chromosome 11 at 23,393,749 bp
  • A to T, chromosome 11 at 59,063,536 bp
  • A to G, chromosome 11 at 61,833,435 bp
  • G to T, chromosome 11 at 73,114,880 bp
  • A to G, chromosome 12 at 17,355,287 bp
  • A to T, chromosome 12 at 52,519,077 bp
  • T to C, chromosome 12 at 59,170,998 bp
  • G to A, chromosome 12 at 69,182,958 bp
  • T to A, chromosome 12 at 103,392,844 bp
  • T to C, chromosome 12 at 103,693,546 bp
  • T to C, chromosome 13 at 58,328,971 bp
  • C to A, chromosome 13 at 67,139,344 bp
  • T to C, chromosome 13 at 100,444,526 bp
  • T to A, chromosome 14 at 54,648,136 bp
  • T to A, chromosome 14 at 55,863,997 bp
  • T to C, chromosome 15 at 89,185,592 bp
  • C to T, chromosome 16 at 18,251,286 bp
  • C to T, chromosome 16 at 70,495,253 bp
  • A to G, chromosome 17 at 6,741,576 bp
  • A to T, chromosome 17 at 8,256,064 bp
  • A to G, chromosome 17 at 29,700,242 bp
  • A to G, chromosome 17 at 34,816,190 bp
  • A to G, chromosome 17 at 34,848,197 bp
  • T to C, chromosome 18 at 22,718,993 bp
  • G to A, chromosome 19 at 24,834,805 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4736 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
041963-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.