Strain Name:
C57BL/6J-MtgxR4764Btlr/Mmmh
Stock Number:
042405-MU
Citation ID:
RRID:MMRRC_042405-MU
Other Names:
R4764 (G1), C57BL/6J-MtgxR4764Btlr
Major Collection:

Gene Information

Myo5a
Name: myosin VA
Synonyms: 9630007J19Rik, MyoVA, flail, MVa, Myo5, Dbv
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 17918
HGNC: HGNC:7602
Homologene: 20100
Pknox1
Name: Pbx/knotted 1 homeobox
Synonyms: D17Wsu76e, PREP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 18771
HGNC: HGNC:9022
Homologene: 3363
Aggf1
Name: angiogenic factor with G patch and FHA domains 1
Synonyms: 2010009L17Rik, 2310029P06Rik, VG5Q
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 66549
Homologene: 41220
Pax6
Name: paired box 6
Synonyms: Gsfaey11, 1500038E17Rik, AEY11, Dey, Dickie's small eye, Pax-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 18508
HGNC: HGNC:8620
Homologene: 1212
Col3a1
Name: collagen, type III, alpha 1
Synonyms: Tsk-2, Tsk2, Col3a-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 12825
HGNC: HGNC:2201
Homologene: 55433
Slit1
Name: slit guidance ligand 1
Synonyms: Slil1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 20562
Homologene: 2302
Myo1e
Name: myosin IE
Synonyms: 9130023P14Rik, 2310020N23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 71602
VEGA: 9
HGNC: HGNC:7599
Homologene: 55864
Foxj2
Name: forkhead box J2
Synonyms: Fhx
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 60611
Homologene: 10187
Elp3
Name: elongator acetyltransferase complex subunit 3
Synonyms: 2610507P14Rik, KAT9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 74195
VEGA: 14
Homologene: 7105
Axin1
Name: axin 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 12005
HGNC: HGNC:903
Homologene: 2614
Rps6ka1
Name: ribosomal protein S6 kinase polypeptide 1
Synonyms: Rsk1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 20111
Homologene: 55703
Zc3h7b
Name: zinc finger CCCH type containing 7B
Synonyms: Scrg3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 20286
VEGA: 15
Homologene: 9735
Hnrnpul1
Name: heterogeneous nuclear ribonucleoprotein U-like 1
Synonyms: E130317O14Rik, Hnrpul1, E1B-AP5, E1BAP5, Hnrnpul
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 232989
Homologene: 31419
Ptprg
Name: protein tyrosine phosphatase, receptor type, G
Synonyms: RPTPgamma, 5430405N12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 19270
HGNC: HGNC:9671
Homologene: 2129
Mtf2
Name: metal response element binding transcription factor 2
Synonyms: 9230112N11Rik, Pcl2, M96, C76717
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 17765
Homologene: 7207
Bptf
Name: bromodomain PHD finger transcription factor
Synonyms: 9430093H17Rik, Falz
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 207165
HGNC: HGNC:3581
Homologene: 114397
Usp22
Name: ubiquitin specific peptidase 22
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 216825
Homologene: 52664
Bdp1
Name: B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
Synonyms: B130055N23Rik, TFIIIB90, TAF3B1, Tfnr, G630013P12Rik, TFIIIB150, TFC5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 544971
Homologene: 34582
Dtna
Name: dystrobrevin alpha
Synonyms: a-DB-1, 87K protein, 2210407P21Rik, alpha-dystrobrevin, A0, adbn, Dtn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 13527
VEGA: 18
HGNC: HGNC:3057
Homologene: 20362
Trio
Name: triple functional domain (PTPRF interacting)
Synonyms: Solo, 6720464I07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 223435
VEGA: 15
Homologene: 20847
Foxi2
Name: forkhead box I2
Synonyms: B130055A05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 270004
Homologene: 18838
Frem1
Name: Fras1 related extracellular matrix protein 1
Synonyms: eyem02Jus, heb, eyes2, crf11, QBRICK
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 329872
Homologene: 27049
Lef1
Name: lymphoid enhancer binding factor 1
Synonyms: lymphoid enhancer factor 1, Lef-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 16842
HGNC: HGNC:6551
Homologene: 7813
Tcea1
Name: transcription elongation factor A (SII) 1
Synonyms: S-II
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 21399
Homologene: 55984
Muc2
Name: mucin 2
Synonyms: 2010015E03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 17831
HGNC: HGNC:7512
Homologene: 136755
Ppp3ca
Name: protein phosphatase 3, catalytic subunit, alpha isoform
Synonyms: Calna, CN, 2900074D19Rik, Caln, PP2BA alpha, PP2B alpha 1, CnA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 19055
HGNC: HGNC:9314
Homologene: 55497
Npat
Name: nuclear protein in the AT region
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 244879
HGNC: HGNC:7896
Homologene: 1888
Extl3
Name: exostoses (multiple)-like 3
Synonyms: 2900009G18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 54616
VEGA: 14
HGNC: HGNC:3518
Homologene: 1103
Pias4
Name: protein inhibitor of activated STAT 4
Synonyms: PIASy
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 59004
Homologene: 104136
Zfhx2
Name: zinc finger homeobox 2
Synonyms: zfh-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 239102
Homologene: 52657
Papln
Name: papilin, proteoglycan-like sulfated glycoprotein
Synonyms: E030033C16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 170721
Homologene: 71541
Cep57l1
Name: centrosomal protein 57-like 1
Synonyms: 4930484D11Rik, 2410017P07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 103268
Homologene: 12254
Sall3
Name: spalt like transcription factor 3
Synonyms: Salt, Spalt, Msal-1, B130022O04Rik, Msal
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 20689
VEGA: 18
Homologene: 18142
Myo16
Name: myosin XVI
Synonyms: BM140241, C230040D10Rik, Nyap3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 244281
Homologene: 34710
Nlrp1b
Name: NLR family, pyrin domain containing 1B
Synonyms: Nalp1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 637515
Homologene: 19080
Olfr884
Name: olfactory receptor 884
Synonyms: MOR162-9P, Olfr1550-ps1, MOR162-11P, GA_x6K02T2PVTD-31726544-31727473, MOR162-13, MOR162-11P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 257996
Homologene: 79400
Ryr3
Name: ryanodine receptor 3
Synonyms: calcium release channel isoform 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 20192
Homologene: 68151
Stxbp5
Name: syntaxin binding protein 5 (tomosyn)
Synonyms: LGL3, 0710001E20Rik, 4930565N16Rik, tomosyn 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 78808
Homologene: 16402
Tmem132e
Name: transmembrane protein 132E
Synonyms: LOC270893
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 270893
Homologene: 41524
Rims1
Name: regulating synaptic membrane exocytosis 1
Synonyms: RIM1alpha, RIM1, C030033M19Rik, RIM1a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 116837
Homologene: 128399
Otog
Name: otogelin
Synonyms: Otgn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 18419
HGNC: HGNC:8516
Homologene: 8421
Rp1
Name: retinitis pigmentosa 1 (human)
Synonyms: mG145, Rp1h, oxygen-regulated protein 1, Orp1, Dcdc3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 19888
Homologene: 4564
Akr1c13
Name: aldo-keto reductase family 1, member C13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 27384
Homologene: 121208
Frmd4a
Name: FERM domain containing 4A
Synonyms: 2700017I06Rik, C230040M21Rik, Gm13190
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 209630
Homologene: 9971
Osbpl6
Name: oxysterol binding protein-like 6
Synonyms: 1110062M20Rik, ORP-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 99031
Homologene: 101447
Acad11
Name: acyl-Coenzyme A dehydrogenase family, member 11
Synonyms: 5730439E10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 102632
Homologene: 49896
Slc7a13
Name: solute carrier family 7, (cationic amino acid transporter, y+ system) member 13
Synonyms: AGT-1, 0610009O04Rik, XAT2, AGT1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 74087
Homologene: 23656
Galc
Name: galactosylceramidase
Synonyms: Gacy, galactocerebrosidase, A930008M05Rik, 2310068B06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 14420
VEGA: 12
HGNC: HGNC:4115
Homologene: 124
C9
Name: complement component 9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 12279
HGNC: HGNC:1358
Homologene: 74406
Atxn7l1
Name: ataxin 7-like 1
Synonyms: Atxn7l4, 2810423G08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 380753
Homologene: 53366
Chst8
Name: carbohydrate sulfotransferase 8
Synonyms: 1500011J21Rik, GalNAc4ST-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 68947
Homologene: 41483
Plscr4
Name: phospholipid scramblase 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235527
Homologene: 23217
Hrh1
Name: histamine receptor H1
Synonyms: Bphs, Hir
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 15465
HGNC: HGNC:5182
Homologene: 668
Ccdc144b
Name: coiled-coil domain containing 144B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 241943
Homologene: 87263
Abcb1a
Name: ATP-binding cassette, sub-family B (MDR/TAP), member 1A
Synonyms: Mdr1a, P-glycoprotein, Evi32, mdr-3, multiple drug resistant 1a, MDR3, Pgp, Pgy-3, Pgy3, P-gp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 18671
HGNC: HGNC:40
Homologene: 55496
Arl8a
Name: ADP-ribosylation factor-like 8A
Synonyms: 1110033P22Rik, Arl10b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 68724
Homologene: 23600
Sdsl
Name: serine dehydratase-like
Synonyms: SDS-RS1, SDH1, 4432411H13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 257635
Homologene: 44224
Usp44
Name: ubiquitin specific peptidase 44
Synonyms: E430004F17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 327799
VEGA: 10
Homologene: 12961
Cbx6
Name: chromobox 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 494448
HGNC: HGNC:1556
Homologene: 8619
Polr2l
Name: polymerase (RNA) II (DNA directed) polypeptide L
Synonyms: 2510029B14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 66491
HGNC: HGNC:9199
Homologene: 129854
Plekhf1
Name: pleckstrin homology domain containing, family F (with FYVE domain) member 1
Synonyms: 1810013P09Rik, LAPF
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 72287
Homologene: 11516
1700001J03Rik
Name: RIKEN cDNA 1700001J03 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 69282
Homologene: 86127
Exoc8
Name: exocyst complex component 8
Synonyms: Exo84p, SEC84, EXO84
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 102058
Homologene: 44545
Tpp1
Name: tripeptidyl peptidase I
Synonyms: Cln2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 12751
HGNC: HGNC:2073
Homologene: 335
Disp1
Name: dispatched RND transporter family member 1
Synonyms: 1190008H24Rik, DispA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 68897
Homologene: 14133
Olfr1377
Name: olfactory receptor 1377
Synonyms: GA_x6K02T2QP88-4453480-4452557, MOR129-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 258913
Homologene: 64929
Fscn3
Name: fascin actin-bundling protein 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 56223
HGNC: HGNC:3961
Homologene: 10475
Cst12
Name: cystatin 12
Synonyms: cystatin TE-1, 1700006F03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 69362
Homologene: 17808
Onecut3
Name: one cut domain, family member 3
Synonyms: OC-3, Oc3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 246086
Homologene: 82258
Alg5
Name: asparagine-linked glycosylation 5 (dolichyl-phosphate beta-glucosyltransferase)
Synonyms: 2600005J22Rik, 1500026A19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 66248
Homologene: 7060
Gm6866
Name: predicted gene 6866
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 628304
Homologene: 80005
1700061E17Rik
Name: RIKEN cDNA 1700061E17 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
2010315B03Rik
Name: RIKEN cDNA 2010315B03 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 630836
Homologene: 136499
Raet1e
Name: retinoic acid early transcript 1E
Synonyms: Rae-1 epsilon
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 379043
Homologene: 134115
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 4,345,878 bp
  • G to A, chromosome 1 at 4,894,944 bp
  • A to C, chromosome 1 at 22,479,462 bp
  • A to C, chromosome 1 at 45,346,110 bp
  • C to A, chromosome 1 at 135,147,099 bp
  • G to T, chromosome 1 at 183,088,096 bp
  • A to T, chromosome 2 at 4,603,448 bp
  • T to A, chromosome 2 at 76,546,000 bp
  • C to A, chromosome 2 at 105,696,502 bp
  • T to A, chromosome 2 at 112,733,031 bp
  • A to G, chromosome 2 at 148,789,473 bp
  • T to G, chromosome 3 at 36,010,660 bp
  • A to G, chromosome 3 at 54,746,473 bp
  • T to C, chromosome 3 at 131,184,733 bp
  • T to C, chromosome 3 at 136,890,489 bp
  • A to G, chromosome 4 at 19,819,390 bp
  • A to T, chromosome 4 at 82,989,189 bp
  • A to T, chromosome 4 at 133,860,557 bp
  • T to A, chromosome 5 at 8,715,732 bp
  • T to C, chromosome 5 at 108,093,352 bp
  • C to T, chromosome 5 at 120,462,054 bp
  • T to G, chromosome 5 at 146,185,219 bp
  • T to A, chromosome 6 at 28,436,201 bp
  • T to C, chromosome 6 at 114,480,535 bp
  • G to T, chromosome 6 at 122,833,271 bp
  • A to G, chromosome 7 at 25,743,011 bp
  • T to C, chromosome 7 at 34,675,724 bp
  • A to G, chromosome 7 at 38,221,598 bp
  • G to T, chromosome 7 at 41,216,118 bp
  • C to T, chromosome 7 at 46,288,519 bp
  • A to T, chromosome 7 at 105,749,251 bp
  • G to T, chromosome 7 at 135,410,667 bp
  • A to T, chromosome 7 at 141,473,396 bp
  • C to T, chromosome 7 at 141,745,608 bp
  • T to C, chromosome 8 at 10,435,880 bp
  • A to G, chromosome 8 at 124,897,575 bp
  • T to G, chromosome 9 at 38,048,140 bp
  • T to C, chromosome 9 at 53,572,620 bp
  • T to C, chromosome 9 at 70,343,135 bp
  • G to T, chromosome 9 at 75,116,336 bp
  • T to C, chromosome 9 at 92,484,780 bp
  • C to A, chromosome 9 at 104,075,877 bp
  • T to C, chromosome 9 at 110,987,350 bp
  • A to C, chromosome 9 at 124,293,766 bp
  • C to A, chromosome 10 at 9,770,623 bp
  • T to G, chromosome 10 at 22,181,332 bp
  • T to C, chromosome 10 at 41,721,682 bp
  • G to T, chromosome 10 at 80,495,707 bp
  • A to G, chromosome 10 at 81,164,034 bp
  • T to A, chromosome 10 at 93,846,071 bp
  • G to A, chromosome 11 at 50,984,775 bp
  • T to A, chromosome 11 at 61,160,636 bp
  • T to A, chromosome 11 at 71,182,663 bp
  • A to T, chromosome 11 at 82,434,512 bp
  • A to T, chromosome 11 at 107,043,694 bp
  • C to T, chromosome 12 at 33,367,626 bp
  • T to C, chromosome 12 at 83,773,937 bp
  • C to T, chromosome 12 at 98,242,744 bp
  • G to A, chromosome 13 at 4,198,497 bp
  • T to A, chromosome 13 at 95,364,713 bp
  • A to G, chromosome 13 at 100,056,267 bp
  • G to A, chromosome 14 at 12,122,068 bp
  • T to C, chromosome 14 at 55,066,915 bp
  • T to C, chromosome 14 at 65,077,320 bp
  • T to A, chromosome 14 at 65,582,929 bp
  • A to T, chromosome 15 at 6,459,643 bp
  • G to A, chromosome 15 at 27,732,538 bp
  • T to C, chromosome 15 at 79,828,680 bp
  • T to C, chromosome 15 at 81,769,183 bp
  • C to A, chromosome 17 at 26,173,756 bp
  • T to A, chromosome 17 at 31,590,713 bp
  • T to G, chromosome 18 at 23,535,149 bp
  • A to G, chromosome 18 at 80,974,476 bp
  • T to A, chromosome 19 at 41,721,044 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4764 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
042405-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.