Strain Name:
C57BL/6J-MtgxR4767Btlr/Mmmh
Stock Number:
042408-MU
Citation ID:
RRID:MMRRC_042408-MU
Other Names:
R4767 (G1), C57BL/6J-MtgxR4767Btlr
Major Collection:

Gene Information

Myo5a
Name: myosin VA
Synonyms: MVa, MyoVA, Myo5, flail, 9630007J19Rik, Dbv
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 17918
HGNC: HGNC:7602
Homologene: 20100
Ap4e1
Name: adaptor-related protein complex AP-4, epsilon 1
Synonyms: 2310033A20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 108011
HGNC: HGNC:573
Homologene: 22397
Lamb1
Name: laminin B1
Synonyms: Lamb-1, C81607, C80098, D130003D08Rik, Lamb1-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 16777
HGNC: HGNC:6486
Homologene: 1722
Pax6
Name: paired box 6
Synonyms: Pax-6, Dey, Dickie's small eye, 1500038E17Rik, AEY11, Gsfaey11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 18508
HGNC: HGNC:8620
Homologene: 1212
Tmem59l
Name: transmembrane protein 59-like
Synonyms: 5330410G16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 67937
Homologene: 8104
Rbm5
Name: RNA binding motif protein 5
Synonyms: D030069N10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 83486
HGNC: HGNC:9902
Homologene: 21177
Tpr
Name: translocated promoter region, nuclear basket protein
Synonyms: 2610029M07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 108989
Homologene: 37753
Atp9b
Name: ATPase, class II, type 9B
Synonyms: IIb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 50771
VEGA: 18
Homologene: 21915
Rnf123
Name: ring finger protein 123
Synonyms: KPC1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 84585
Homologene: 11112
Syne1
Name: spectrin repeat containing, nuclear envelope 1
Synonyms: nesprin-1, SYNE-1, enaptin165, A330049M09Rik, C130039F11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 64009
VEGA: 10
Homologene: 52329
Galnt5
Name: polypeptide N-acetylgalactosaminyltransferase 5
Synonyms: ppGaNTase-T5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241391
HGNC: HGNC:4127
Homologene: 8733
Cic
Name: capicua transcriptional repressor
Synonyms: 1200010B10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 71722
Homologene: 87637
Sox14
Name: SRY (sex determining region Y)-box 14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 20669
Homologene: 31224
Apoc3
Name: apolipoprotein C-III
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 11814
HGNC: HGNC:610
Homologene: 136634
Epg5
Name: ectopic P-granules autophagy protein 5 homolog (C. elegans)
Synonyms: 5430411K18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 100502841
VEGA: 18
Homologene: 14575
Cemip
Name: cell migration inducing protein, hyaluronan binding
Synonyms: 12H19.01.T7, 6330404C01Rik, 9930013L23Rik, Hybid
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 80982
Homologene: 10268
Eva1c
Name: eva-1 homolog C (C. elegans)
Synonyms: 1700092M14Rik, Fam176c, 4931408A02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 70967
Homologene: 14383
Plaa
Name: phospholipase A2, activating protein
Synonyms: D4Ertd618e, Ufd3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 18786
HGNC: HGNC:9043
Homologene: 3138
Adam19
Name: a disintegrin and metallopeptidase domain 19 (meltrin beta)
Synonyms: Mltnb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 11492
HGNC: HGNC:197
Homologene: 74925
Csnk1d
Name: casein kinase 1, delta
Synonyms: 1200006A05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 104318
HGNC: HGNC:2452
Homologene: 74841
Ddx21
Name: DExD box helicase 21
Synonyms: RH II/Gu, D10Ertd645e, D10Wsu42e, RH-II/Gualpha, DEAD (Asp-Glu-Ala-Asp) box polypeptide 21
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 56200
VEGA: 10
HGNC: HGNC:2744
Homologene: 3473
Nhlrc2
Name: NHL repeat containing 2
Synonyms: 1200003G01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 66866
VEGA: 19
Homologene: 12048
Trpc6
Name: transient receptor potential cation channel, subfamily C, member 6
Synonyms: mtrp6, Trrp6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 22068
VEGA: 9
Homologene: 37944
Dnah5
Name: dynein, axonemal, heavy chain 5
Synonyms: Mdnah5, b2b1154Clo, b2b1134Clo, b2b1537Clo, b2b1565Clo, Dnahc5, b2b3491Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 110082
HGNC: HGNC:2950
Homologene: 1048
Lama3
Name: laminin, alpha 3
Synonyms: nicein, 150kDa, [a]3B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 16774
HGNC: HGNC:6483
Homologene: 18279
Ephb6
Name: Eph receptor B6
Synonyms: Mep, Cekl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 13848
HGNC: HGNC:3396
Homologene: 20940
Rnf185
Name: ring finger protein 185
Synonyms: 1700022N24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 193670
Homologene: 34298
Nlrp2
Name: NLR family, pyrin domain containing 2
Synonyms: PYPAF2, E330007A02Rik, Nalp2, Pan1, Nbs1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 232827
Homologene: 56789
Tbc1d17
Name: TBC1 domain family, member 17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233204
Homologene: 11656
Duox1
Name: dual oxidase 1
Synonyms: NOXEF1, THOX1, LNOX1, 9930101G15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 99439
HGNC: HGNC:3062
Homologene: 68136
Tmem266
Name: transmembrane protein 266
Synonyms: AI118078
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 244886
Homologene: 17551
Olfr347
Name: olfactory receptor 347
Synonyms: GA_x6K02T2NLDC-33428755-33429693, MOR136-9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258945
Homologene: 51790
Cracr2a
Name: calcium release activated channel regulator 2A
Synonyms: LOC381812, LOC243645, Efcab4b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 381812
Homologene: 41883
Lao1
Name: L-amino acid oxidase 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100470
Homologene: 44223
Olfr1497
Name: olfactory receptor 1497
Synonyms: GA_x6K02T2RE5P-4127765-4126821, MOR212-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 258736
Homologene: 17373
Ercc4
Name: excision repair cross-complementing rodent repair deficiency, complementation group 4
Synonyms: Xpf
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 50505
HGNC: HGNC:3436
Homologene: 3836
Zfp948
Name: zinc finger protein 948
Synonyms: BC049807
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 381066
VEGA: 17
Sh3bp1
Name: SH3-domain binding protein 1
Synonyms: 3BP-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 20401
Homologene: 7534
Slfn8
Name: schlafen 8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 276950
Homologene: 45432
Vmn2r4
Name: vomeronasal 2, receptor 4
Synonyms: EG637053
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 637053
Homologene: 129754
Olfr76
Name: olfactory receptor 76
Synonyms: V5, MOR215-3, GA_x6K02T2RE5P-2479601-2478648
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 258677
HGNC: HGNC:8319
Homologene: 17342
Parp8
Name: poly (ADP-ribose) polymerase family, member 8
Synonyms: 2810430O08Rik, D13Ertd275e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 52552
VEGA: 13
Homologene: 11621
Thnsl2
Name: threonine synthase-like 2 (bacterial)
Synonyms: TSH2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232078
Homologene: 5489
Mindy4
Name: MINDY lysine 48 deubiquitinase 4
Synonyms: LOC384387, C330043M08Rik, Fam188b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 330323
Homologene: 49991
Crocc2
Name: ciliary rootlet coiled-coil, rootletin family member 2
Synonyms: LOC381284, E030010N08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 381284
Homologene: 141152
Vmn2r86
Name: vomeronasal 2, receptor 86
Synonyms: EG625109
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 625109
Homologene: 129606
Tbrg4
Name: transforming growth factor beta regulated gene 4
Synonyms: TB-12, Cpr2, 2310042P22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 21379
Homologene: 31259
Tspan10
Name: tetraspanin 10
Synonyms: Ocsp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 208634
Homologene: 49972
Vmn1r183
Name: vomeronasal 1 receptor 183
Synonyms: LOC209824, V1rd15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 209824
Homologene: 104166
Saxo1
Name: stabilizer of axonemal microtubules 1
Synonyms: 4930500O09Rik, Fam154a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 75811
Homologene: 27548
Olfr938
Name: olfactory receptor 938
Synonyms: GA_x6K02T2PVTD-32774646-32773699, MOR171-25
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258430
VEGA: 9
Pi15
Name: peptidase inhibitor 15
Synonyms: P24TI, P25TI, SugarCrisp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 94227
HGNC: HGNC:8946
Homologene: 22935
Aig1
Name: androgen-induced 1
Synonyms: CGI-103, 1500031O19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 66253
Homologene: 32297
Ubox5
Name: U box domain containing 5
Synonyms: UIP5, 1500010O06Rik, C330018L13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 140629
Homologene: 8972
Olfr107
Name: olfactory receptor 107
Synonyms: GA_x6K02T2PSCP-1867165-1868094, MOR156-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 258504
Homologene: 115498
Sall2
Name: spalt like transcription factor 2
Synonyms: Msal-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 50524
Homologene: 9269
Dcun1d4
Name: DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100737
Homologene: 22867
Smoc1
Name: SPARC related modular calcium binding 1
Synonyms: SPARC-related protein, SRG, 2600002F22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 64075
Homologene: 56943
Alx1
Name: ALX homeobox 1
Synonyms: Cart1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216285
HGNC: HGNC:1494
Homologene: 5075
Haus4
Name: HAUS augmin-like complex, subunit 4
Synonyms: 9430093H08Rik, D14Ertd500e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 219072
VEGA: 14
Homologene: 9854
Spata31d1a
Name: spermatogenesis associated 31 subfamily D, member 1A
Synonyms: 1700013B16Rik, Fam75d3, Fam75d1a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 72219
VEGA: 13
Homologene: 122131
Igkv9-120
Name: immunoglobulin kappa chain variable 9-120
Synonyms: Gm5571
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 434025
Ighv1-13
Name: immunoglobulin heavy variable V1-13
Synonyms: Gm17686
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 780865
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 17,602,766 bp
  • G to A, chromosome 1 at 93,202,856 bp
  • T to C, chromosome 1 at 150,430,529 bp
  • A to T, chromosome 2 at 36,734,323 bp
  • T to A, chromosome 2 at 58,028,144 bp
  • T to C, chromosome 2 at 105,695,360 bp
  • A to G, chromosome 2 at 122,333,441 bp
  • T to C, chromosome 2 at 127,060,438 bp
  • A to T, chromosome 2 at 130,591,894 bp
  • C to T, chromosome 3 at 64,390,976 bp
  • T to C, chromosome 4 at 86,445,807 bp
  • A to G, chromosome 4 at 94,586,258 bp
  • T to C, chromosome 4 at 118,967,988 bp
  • G to A, chromosome 5 at 73,534,635 bp
  • A to T, chromosome 6 at 41,614,185 bp
  • A to G, chromosome 6 at 55,260,565 bp
  • G to T, chromosome 6 at 68,050,367 bp
  • A to T, chromosome 6 at 71,134,295 bp
  • A to T, chromosome 6 at 127,611,507 bp
  • C to T, chromosome 7 at 5,328,024 bp
  • TATCCATC to TATC, chromosome 7 at 24,055,106 bp
  • T to C, chromosome 7 at 25,271,600 bp
  • A to G, chromosome 7 at 44,841,352 bp
  • T to G, chromosome 7 at 83,973,306 bp
  • C to A, chromosome 8 at 70,486,098 bp
  • T to C, chromosome 9 at 8,643,686 bp
  • T to C, chromosome 9 at 39,078,692 bp
  • C to A, chromosome 9 at 46,234,535 bp
  • C to T, chromosome 9 at 55,380,741 bp
  • T to C, chromosome 9 at 75,144,076 bp
  • A to T, chromosome 9 at 99,875,633 bp
  • C to A, chromosome 9 at 107,745,213 bp
  • C to A, chromosome 9 at 108,052,089 bp
  • T to A, chromosome 10 at 5,344,866 bp
  • T to C, chromosome 10 at 13,801,858 bp
  • A to G, chromosome 10 at 62,591,972 bp
  • A to T, chromosome 10 at 103,025,186 bp
  • A to T, chromosome 10 at 130,455,737 bp
  • A to G, chromosome 11 at 3,432,551 bp
  • A to C, chromosome 11 at 6,620,909 bp
  • T to C, chromosome 11 at 46,138,977 bp
  • G to A, chromosome 11 at 83,003,197 bp
  • A to T, chromosome 11 at 120,446,166 bp
  • A to G, chromosome 11 at 120,969,128 bp
  • A to G, chromosome 12 at 31,308,011 bp
  • G to A, chromosome 12 at 81,104,773 bp
  • A to G, chromosome 12 at 114,630,936 bp
  • T to C, chromosome 13 at 59,701,155 bp
  • T to C, chromosome 13 at 116,868,536 bp
  • C to A, chromosome 14 at 52,314,960 bp
  • T to C, chromosome 14 at 54,548,885 bp
  • C to T, chromosome 15 at 28,270,474 bp
  • T to C, chromosome 15 at 78,904,497 bp
  • C to A, chromosome 16 at 13,122,095 bp
  • A to T, chromosome 16 at 90,904,347 bp
  • T to A, chromosome 17 at 21,588,307 bp
  • T to A, chromosome 17 at 37,406,200 bp
  • T to C, chromosome 18 at 12,500,563 bp
  • C to A, chromosome 18 at 78,023,283 bp
  • G to T, chromosome 18 at 80,753,070 bp
  • G to T, chromosome 19 at 12,119,936 bp
  • A to T, chromosome 19 at 13,795,045 bp
  • G to A, chromosome 19 at 56,570,466 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4767 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
042408-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.