Strain Name:
C57BL/6J-MtgxR4770Btlr/Mmmh
Stock Number:
042410-MU
Citation ID:
RRID:MMRRC_042410-MU
Other Names:
R4770 (G1), C57BL/6J-MtgxR4770Btlr
Major Collection:

Gene Information

Prkaca
Name: protein kinase, cAMP dependent, catalytic, alpha
Synonyms: C alpha, PKA, Pkaca, Cs
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 18747
HGNC: HGNC:9380
Homologene: 121574
Lrrn3
Name: leucine rich repeat protein 3, neuronal
Synonyms: NLRR-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 16981
VEGA: 12
Homologene: 36315
Epb41l1
Name: erythrocyte membrane protein band 4.1 like 1
Synonyms: Epb4.1l1, 4.1N
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 13821
HGNC: HGNC:3378
Homologene: 8126
Gtf2i
Name: general transcription factor II I
Synonyms: 6030441I21Rik, TFII-I, BAP-135
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 14886
HGNC: HGNC:4659
Homologene: 7748
Gli2
Name: GLI-Kruppel family member GLI2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 14633
HGNC: HGNC:4318
Homologene: 12725
Plekha1
Name: pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
Synonyms: TAPP1, C920009D07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 101476
Homologene: 11001
Fgr
Name: FGR proto-oncogene, Src family tyrosine kinase
Synonyms: Ali18, Mhdaali18
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 14191
HGNC: HGNC:3697
Homologene: 3842
Dscaml1
Name: DS cell adhesion molecule like 1
Synonyms: 4930435C18Rik, 4921507G06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 114873
VEGA: 9
Homologene: 79549
Dapp1
Name: dual adaptor for phosphotyrosine and 3-phosphoinositides 1
Synonyms: Bam32
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 26377
Homologene: 32138
Mycbp2
Name: MYC binding protein 2, E3 ubiquitin protein ligase
Synonyms: C130061D10Rik, Phr1, Pam
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 105689
Homologene: 9005
Ezh2
Name: enhancer of zeste 2 polycomb repressive complex 2 subunit
Synonyms: KMT6, Enx-1, Enx1h
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 14056
HGNC: HGNC:3527
Homologene: 37926
Syncrip
Name: synaptotagmin binding, cytoplasmic RNA interacting protein
Synonyms: hnRNP Q, GRY-RBP, pp68, Nsap1, Nsap1l, RRM RNA binding protein GRY-RBP, 2610109K23Rik, 4632417O19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 56403
Homologene: 4648
Agps
Name: alkylglycerone phosphate synthase
Synonyms: ADAPS, 9930035G10Rik, bs2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228061
HGNC: HGNC:327
Homologene: 2716
Parvb
Name: parvin, beta
Synonyms: D15Gsk1, affixin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 170736
Homologene: 8342
Anapc1
Name: anaphase promoting complex subunit 1
Synonyms: tsg24, Mcpr, 2610021O03Rik, Apc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 17222
Homologene: 7414
Rnf20
Name: ring finger protein 20
Synonyms: 4833430L21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 109331
Homologene: 5571
Gapvd1
Name: GTPase activating protein and VPS9 domains 1
Synonyms: 2010005B09Rik, 4432404J10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 66691
Homologene: 32637
Snhg5
Name: small nucleolar RNA host gene 5
Synonyms: 2810026P18Rik, mU50HG-b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 72655
Son
Name: Son DNA binding protein
Synonyms: 2900011L12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 20658
Homologene: 10551
C2cd3
Name: C2 calcium-dependent domain containing 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 277939
Homologene: 19524
Snap91
Name: synaptosomal-associated protein 91
Synonyms: F1-20, AP180, 91kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 20616
Homologene: 8429
Cntfr
Name: ciliary neurotrophic factor receptor
Synonyms: Cntfralpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 12804
HGNC: HGNC:2170
Homologene: 9619
Zfp65
Name: zinc finger protein 65
Synonyms: KRAB5, Zfp71-rs1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 235907
Homologene: 87875
Itsn2
Name: intersectin 2
Synonyms: Eh domain, SH3 domain regulator of endocytosis 2, Sh3p18, Sh3d1B, Ese2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 20403
VEGA: 12
HGNC: HGNC:6184
Homologene: 22627
Edrf1
Name: erythroid differentiation regulatory factor 1
Synonyms: 2700050L05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 214764
Homologene: 27985
Trerf1
Name: transcriptional regulating factor 1
Synonyms: Trep132, Trep-132, 9430096I18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224829
Homologene: 14129
Nr1d1
Name: nuclear receptor subfamily 1, group D, member 1
Synonyms: A530070C09Rik, REV-ERBalpha, rev-erbA(alpha)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217166
HGNC: HGNC:7962
Homologene: 23324
Ryr1
Name: ryanodine receptor 1, skeletal muscle
Synonyms: Ryr, skrr, calcium release channel isoform 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 20190
Homologene: 68069
Pou4f2
Name: POU domain, class 4, transcription factor 2
Synonyms: Brn-3.2, Pou4f-rs1, Brn3b, Brn-3b, mBrn3-3R
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 18997
HGNC: HGNC:9219
Homologene: 20959
Cubn
Name: cubilin (intrinsic factor-cobalamin receptor)
Synonyms: D2Wsu88e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 65969
HGNC: HGNC:2548
Homologene: 37434
Exosc9
Name: exosome component 9
Synonyms: PM/Scl-75, p5, RRP45, Pmscl1, p6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 50911
HGNC: HGNC:9137
Homologene: 3693
Nr3c2
Name: nuclear receptor subfamily 3, group C, member 2
Synonyms: MR, mineralocorticoid receptor, Mlr, aldosterone receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 110784
HGNC: HGNC:7979
Homologene: 121495
Uggt2
Name: UDP-glucose glycoprotein glucosyltransferase 2
Synonyms: A230065J02Rik, 3110027P15Rik, Ugcgl2, 3110001A05Rik, 1810064L21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 66435
Homologene: 56875
Kif27
Name: kinesin family member 27
Synonyms: 4930517I18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 75050
VEGA: 13
Homologene: 69235
Ush2a
Name: usherin
Synonyms: A930037M10Rik, MUSH2A, LOC381317, LOC269160, Ushrn, A930011D15Rik, Ush2a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 22283
Homologene: 66151
Zfp646
Name: zinc finger protein 646
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233905
Homologene: 8802
Il11ra1
Name: interleukin 11 receptor, alpha chain 1
Synonyms: Il-11ra, NR1, Il11ra, Il-11ra-alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 16157
HGNC: HGNC:5967
Homologene: 88705
Neb
Name: nebulin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 17996
HGNC: HGNC:7720
Homologene: 136285
Gbp5
Name: guanylate binding protein 5
Synonyms: Gbp5a, 5330409J06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229898
Homologene: 14183
Ppfia2
Name: protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
Synonyms: Liprin-alpha2, E130120L08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 327814
VEGA: 10
HGNC: HGNC:9246
Homologene: 27953
Ccser1
Name: coiled-coil serine rich 1
Synonyms: 6230405M12Rik, C130092O11Rik, Fam190a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232035
Homologene: 28086
Mast3
Name: microtubule associated serine/threonine kinase 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 546071
Homologene: 66191
Fam160b2
Name: family with sequence similarity 160, member B2
Synonyms: G430067P06Rik, Rai16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 239170
VEGA: 14
Homologene: 23379
Pik3r6
Name: phosphoinositide-3-kinase regulatory subunit 5
Synonyms: p84 Pikap, p87PIKAP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 104709
Homologene: 46215
Amigo3
Name: adhesion molecule with Ig like domain 3
Synonyms: E430002N15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 320844
Homologene: 45570
Duox2
Name: dual oxidase 2
Synonyms: A430065P05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 214593
Homologene: 9689
Ankrd36
Name: ankyrin repeat domain 36
Synonyms: 1700008J08Rik, 1700012M14Rik, GC3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 76389
Homologene: 137366
Abca8a
Name: ATP-binding cassette, sub-family A (ABC1), member 8a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217258
HGNC: HGNC:38
Homologene: 131160
Zfp747
Name: zinc finger protein 747
Synonyms: 6430604K15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 269997
Homologene: 118005
Myo1c
Name: myosin IC
Synonyms: C80397, mm1beta, myr2, myosin-Ibeta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 17913
HGNC: HGNC:7597
Homologene: 32046
Slco2b1
Name: solute carrier organic anion transporter family, member 2b1
Synonyms: Slc21a9, OATP-B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 101488
Homologene: 21419
Pde4dip
Name: phosphodiesterase 4D interacting protein (myomegalin)
Synonyms: D130016K21Rik, 4732458A06Rik, 9430063L05Rik, D3Bwg1078e, Usmg4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 83679
Homologene: 66961
Ngef
Name: neuronal guanine nucleotide exchange factor
Synonyms: ephexin, Tims2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 53972
HGNC: HGNC:7807
Homologene: 75120
Greb1
Name: gene regulated by estrogen in breast cancer protein
Synonyms: 5730583K22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 268527
Homologene: 8780
Tas2r125
Name: taste receptor, type 2, member 125
Synonyms: Tas2r25, mGR25, mt2r59, T2R26
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 387352
Homologene: 87294
Ccdc51
Name: coiled-coil domain containing 51
Synonyms: Mitok, 5730568A12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 66658
Homologene: 11646
Olfm5
Name: olfactomedin 5
Synonyms: E030002O03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 244180
Homologene: 18253
Xkr4
Name: X-linked Kx blood group related 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 497097
Homologene: 45848
Mast1
Name: microtubule associated serine/threonine kinase 1
Synonyms: 9430008B02Rik, SAST, SAST170
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 56527
Homologene: 10543
Phf2
Name: PHD finger protein 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 18676
VEGA: 13
HGNC: HGNC:8920
Homologene: 3934
Pramel26
Name: PRAME like 26
Synonyms: Gm13084
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 381569
Homologene: 77858
Nanog
Name: Nanog homeobox
Synonyms: ecat4, ENK, 2410002E02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 71950
Homologene: 78027
Itga2b
Name: integrin alpha 2b
Synonyms: GP IIb, CD41, platelet glycoprotein IIb, GpIIb, alphaIIb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 16399
HGNC: HGNC:6138
Homologene: 37304
Ecm1
Name: extracellular matrix protein 1
Synonyms: p85
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 13601
HGNC: HGNC:3153
Homologene: 3260
Setd7
Name: SET domain containing (lysine methyltransferase) 7
Synonyms: KMT7, 1600028F23Rik, Set7/9, Set7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 73251
Homologene: 12741
Gm9934
Name: predicted gene 9934
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Cyp2d9
Name: cytochrome P450, family 2, subfamily d, polypeptide 9
Synonyms: testosterone 16alpha-hydroxylase, Cyp2d, P450-2D
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 13105
VEGA: 15
Homologene: 86099
Ajm1
Name: apical junction component 1
Synonyms: Gm996, LOC381353
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 381353
Homologene: 19943
Zfp69
Name: zinc finger protein 69
Synonyms: Zfp63, KRAB2, LOC381549
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 381549
Homologene: 45693
Serpinb3d
Name: serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3D
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 394252
Homologene: 130559
Cox10
Name: heme A:farnesyltransferase cytochrome c oxidase assembly factor 10
Synonyms: 2410004F01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 70383
HGNC: HGNC:2260
Homologene: 80170
Atp8b2
Name: ATPase, class I, type 8B, member 2
Synonyms: Id
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 54667
Homologene: 23226
Poglut1
Name: protein O-glucosyltransferase 1
Synonyms: Rumi, Ktelc1, 9630046K23Rik, wsnp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 224143
Homologene: 41353
Asic2
Name: acid-sensing (proton-gated) ion channel 2
Synonyms: Accn1, BNaC1a, Mdeg, BNC1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 11418
HGNC: HGNC:99
Homologene: 137202
Zfp850
Name: zinc finger protein 850
Synonyms: C130069I09Rik, Gm4636
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 100043772
H2-DMb2
Name: histocompatibility 2, class II, locus Mb2
Synonyms: H2-M beta2, H-2Mb2, H2-Mb2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 15000
HGNC: HGNC:4935
Homologene: 68231
Tmem115
Name: transmembrane protein 115
Synonyms: Pl6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 56395
Homologene: 135207
Pinx1
Name: PIN2/TERF1 interacting, telomerase inhibitor 1
Synonyms: 2210403I16Rik, LPTS, 2610028A01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 72400
VEGA: 14
Homologene: 134540
Dmrtb1
Name: DMRT-like family B with proline-rich C-terminal, 1
Synonyms: Dmrt6, Prp13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 56296
Homologene: 13207
Fam89b
Name: family with sequence similarity 89, member B
Synonyms: Mtvr2, Fam89b, 1110021A21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 17826
Homologene: 18749
Odf3b
Name: outer dense fiber of sperm tails 3B
Synonyms: 2010001J22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 70113
VEGA: 15
Homologene: 28256
Rnf25
Name: ring finger protein 25
Synonyms: 0610009H16Rik, AO7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 57751
Homologene: 11193
Ttc39c
Name: tetratricopeptide repeat domain 39C
Synonyms: 1700008N02Rik, 2810439F02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 72747
Homologene: 124438
Lad1
Name: ladinin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 16763
HGNC: HGNC:6472
Homologene: 4059
Ring1
Name: ring finger protein 1
Synonyms: Ring1A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 19763
Homologene: 68283
RP23-191E1.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Etohd2
Name: ethanol decreased 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 13996
4930506C21Rik
Name: RIKEN cDNA 4930506C21 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 75060
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 3,216,491 bp
  • G to A, chromosome 1 at 74,593,940 bp
  • C to T, chromosome 1 at 87,477,561 bp
  • A to G, chromosome 1 at 107,078,278 bp
  • C to A, chromosome 1 at 118,982,588 bp
  • A to T, chromosome 1 at 135,825,793 bp
  • G to T, chromosome 1 at 188,549,879 bp
  • T to C, chromosome 2 at 13,314,767 bp
  • G to A, chromosome 2 at 25,579,747 bp
  • A to G, chromosome 2 at 34,691,181 bp
  • T to C, chromosome 2 at 52,149,153 bp
  • T to A, chromosome 2 at 75,891,855 bp
  • A to T, chromosome 2 at 122,284,916 bp
  • T to C, chromosome 2 at 128,686,060 bp
  • T to A, chromosome 2 at 156,529,424 bp
  • T to C, chromosome 3 at 36,553,835 bp
  • T to C, chromosome 3 at 51,521,422 bp
  • T to A, chromosome 3 at 89,957,067 bp
  • A to G, chromosome 3 at 95,737,961 bp
  • G to T, chromosome 3 at 97,767,084 bp
  • T to C, chromosome 3 at 106,297,357 bp
  • A to G, chromosome 3 at 137,981,308 bp
  • A to T, chromosome 3 at 142,508,076 bp
  • A to T, chromosome 4 at 41,663,282 bp
  • A to G, chromosome 4 at 41,768,187 bp
  • T to A, chromosome 4 at 49,633,412 bp
  • C to T, chromosome 4 at 107,683,789 bp
  • A to G, chromosome 4 at 120,934,417 bp
  • C to T, chromosome 4 at 132,987,291 bp
  • C to T, chromosome 4 at 143,811,949 bp
  • T to A, chromosome 5 at 134,243,560 bp
  • A to T, chromosome 6 at 47,540,696 bp
  • A to G, chromosome 6 at 61,311,501 bp
  • T to G, chromosome 6 at 122,711,591 bp
  • A to G, chromosome 6 at 132,909,787 bp
  • T to C, chromosome 7 at 27,984,986 bp
  • G to T, chromosome 7 at 29,109,282 bp
  • A to G, chromosome 7 at 93,052,984 bp
  • C to T, chromosome 7 at 99,670,949 bp
  • A to G, chromosome 7 at 100,443,435 bp
  • A to G, chromosome 7 at 104,160,478 bp
  • C to T, chromosome 7 at 127,375,799 bp
  • T to A, chromosome 7 at 127,883,477 bp
  • T to A, chromosome 7 at 130,904,899 bp
  • G to T, chromosome 7 at 133,658,610 bp
  • G to A, chromosome 8 at 70,786,220 bp
  • A to G, chromosome 8 at 76,908,243 bp
  • T to A, chromosome 8 at 78,436,401 bp
  • A to G, chromosome 8 at 83,990,870 bp
  • A to G, chromosome 8 at 84,929,246 bp
  • C to T, chromosome 9 at 45,670,106 bp
  • G to A, chromosome 9 at 86,773,601 bp
  • T to A, chromosome 9 at 88,479,852 bp
  • C to T, chromosome 9 at 88,522,371 bp
  • G to A, chromosome 9 at 107,534,957 bp
  • A to T, chromosome 9 at 108,053,535 bp
  • A to G, chromosome 9 at 109,090,910 bp
  • G to C, chromosome 10 at 106,762,117 bp
  • G to T, chromosome 11 at 5,590,870 bp
  • G to A, chromosome 11 at 63,964,163 bp
  • T to A, chromosome 11 at 68,529,894 bp
  • T to A, chromosome 11 at 75,660,313 bp
  • A to C, chromosome 11 at 80,971,492 bp
  • A to G, chromosome 11 at 98,770,645 bp
  • A to G, chromosome 11 at 102,460,756 bp
  • A to G, chromosome 11 at 110,071,515 bp
  • T to A, chromosome 12 at 4,627,892 bp
  • A to T, chromosome 12 at 16,681,356 bp
  • T to A, chromosome 12 at 41,452,443 bp
  • A to G, chromosome 13 at 48,803,603 bp
  • G to A, chromosome 13 at 58,344,377 bp
  • A to G, chromosome 13 at 59,772,884 bp
  • A to T, chromosome 13 at 67,708,358 bp
  • T to G, chromosome 14 at 63,872,371 bp
  • T to A, chromosome 14 at 70,588,287 bp
  • T to A, chromosome 14 at 103,219,944 bp
  • A to T, chromosome 14 at 119,029,054 bp
  • T to A, chromosome 15 at 82,452,573 bp
  • T to C, chromosome 15 at 84,303,905 bp
  • A to G, chromosome 15 at 89,379,123 bp
  • A to G, chromosome 16 at 38,534,757 bp
  • T to A, chromosome 16 at 91,658,868 bp
  • C to T, chromosome 17 at 8,293,545 bp
  • G to A, chromosome 17 at 34,023,387 bp
  • G to C, chromosome 17 at 34,148,724 bp
  • G to A, chromosome 17 at 47,319,655 bp
  • T to C, chromosome 18 at 12,734,928 bp
  • C to A, chromosome 19 at 5,729,454 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4770 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
042410-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.