Strain Name:
C57BL/6J-MtgxR4806Btlr/Mmmh
Stock Number:
042425-MU
Citation ID:
RRID:MMRRC_042425-MU
Other Names:
R4806 (G1), C57BL/6J-MtgxR4806Btlr
Major Collection:

Gene Information

Tln2
Name: talin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 70549
VEGA: 9
Homologene: 56692
Xrcc1
Name: X-ray repair complementing defective repair in Chinese hamster cells 1
Synonyms: Xrcc-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 22594
Homologene: 31368
Lpp
Name: LIM domain containing preferred translocation partner in lipoma
Synonyms: B130055L10Rik, 9430020K16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 210126
VEGA: 16
HGNC: HGNC:6679
Homologene: 4075
Plxnd1
Name: plexin D1
Synonyms: 6230425C21Rik, b2b553Clo, b2b1863Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 67784
HGNC: HGNC:9107
Homologene: 22866
Mapkap1
Name: mitogen-activated protein kinase associated protein 1
Synonyms: D230039K05Rik, Sin1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227743
Homologene: 11473
Prex2
Name: phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
Synonyms: 6230420N16Rik, C030045D06Rik, Depdc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 109294
Homologene: 23523
Zfp341
Name: zinc finger protein 341
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228807
Homologene: 13127
Fry
Name: FRY microtubule binding protein
Synonyms: cg003, 9330186A19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 320365
Homologene: 113770
Tsc22d1
Name: TSC22 domain family, member 1
Synonyms: TSC-22, Egr5, Tgfb1i4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 21807
Homologene: 7573
Csde1
Name: cold shock domain containing E1, RNA binding
Synonyms: unr, D3Jfr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229663
Homologene: 5179
Gtf2ird1
Name: general transcription factor II I repeat domain-containing 1
Synonyms: WBSCR11, Cream1, GTF3, MusTRD1, binding factor for early enhancer, BEN, ESTM9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 57080
HGNC: HGNC:4661
Homologene: 4158
Sin3a
Name: transcriptional regulator, SIN3A (yeast)
Synonyms: Sin3, mSin3A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 20466
Homologene: 32124
Mc4r
Name: melanocortin 4 receptor
Synonyms: Fatboy, Pkcp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 17202
VEGA: 18
HGNC: HGNC:6932
Homologene: 4320
Acin1
Name: apoptotic chromatin condensation inducer 1
Synonyms: 2610510L13Rik, 2610036I19Rik, Acinus
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 56215
Homologene: 22853
Cklf
Name: chemokine-like factor
Synonyms: CKLF5, chemokine-like factor 4, Cklf6, 1700001C14Rik, HSPC224, UCK-1, CKLF4, CKLF3, CKLF2, CKLF1, C32, A730028G07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 75458
Homologene: 9663
Csf2rb2
Name: colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)
Synonyms: AIC2A, Il3r, Il3rb2, Bil3, BetaIl3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 12984
VEGA: 15
HGNC: HGNC:2436
Homologene: 339
Med13
Name: mediator complex subunit 13
Synonyms: Trap240, 1110067M05Rik, Thrap1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 327987
Homologene: 21067
Psmg2
Name: proteasome (prosome, macropain) assembly chaperone 2
Synonyms: 1700017I17Rik, Clast3, Tnfsf5ip1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 107047
VEGA: 18
Homologene: 41354
Glmp
Name: glycosylated lysosomal membrane protein
Synonyms: NCU-G1, 0610031J06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 56700
Homologene: 10562
Dmkn
Name: dermokine
Synonyms: cI-36, sk30, sk89, Dmkn, dermokine, 1110014F24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 73712
Homologene: 136295
Ighmbp2
Name: immunoglobulin mu binding protein 2
Synonyms: Catf1, AEP, sma, Smbp2, Smubp2, p110 subunit, RIPE3b1, Smbp-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 20589
HGNC: HGNC:5542
Homologene: 1642
Kif3b
Name: kinesin family member 3B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 16569
HGNC: HGNC:6320
Homologene: 55849
2310022A10Rik
Name: RIKEN cDNA 2310022A10 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 66367
Homologene: 35272
Ints2
Name: integrator complex subunit 2
Synonyms: 2810417D08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 70422
Homologene: 10801
Ythdc1
Name: YTH domain containing 1
Synonyms: A730098D12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231386
Homologene: 15796
Dpp9
Name: dipeptidylpeptidase 9
Synonyms: DPRP2, 6430584G11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224897
VEGA: 17
Homologene: 16385
Prdm10
Name: PR domain containing 10
Synonyms: tristanin, LOC382066
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 382066
Homologene: 45718
Syk
Name: spleen tyrosine kinase
Synonyms: Sykb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 20963
Homologene: 2390
Dnah10
Name: dynein, axonemal, heavy chain 10
Synonyms: Dnahc10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 56087
HGNC: HGNC:2941
Homologene: 25816
Myh11
Name: myosin, heavy polypeptide 11, smooth muscle
Synonyms: smMHC, SM2, SM1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 17880
VEGA: 16
HGNC: HGNC:7569
Homologene: 128512
Plb1
Name: phospholipase B1
Synonyms: 4632413E21Rik, 4930433E17Rik, 4930539A06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 665270
Homologene: 82108
Cntnap4
Name: contactin associated protein-like 4
Synonyms: Caspr4, E130114F09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 170571
Homologene: 24912
Arhgap5
Name: Rho GTPase activating protein 5
Synonyms: p190-B, p190B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 11855
VEGA: 12
HGNC: HGNC:675
Homologene: 907
Csmd3
Name: CUB and Sushi multiple domains 3
Synonyms: 4930500N14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239420
Homologene: 65982
Slco1a1
Name: solute carrier organic anion transporter family, member 1a1
Synonyms: Oatp1, Slc21a1, Oatp1a1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 28248
Homologene: 137261
Gpr179
Name: G protein-coupled receptor 179
Synonyms: 5330439C02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217143
Homologene: 34917
Kcnq4
Name: potassium voltage-gated channel, subfamily Q, member 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 60613
HGNC: HGNC:6298
Homologene: 78107
Ros1
Name: Ros1 proto-oncogene
Synonyms: Ros-1, c-ros
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 19886
Homologene: 2207
Naip1
Name: NLR family, apoptosis inhibitory protein 1
Synonyms: D13Lsd1, Naip, Birc1a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 17940
VEGA: 13
HGNC: HGNC:7634
Homologene: 113589
4930562C15Rik
Name: RIKEN cDNA 4930562C15 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 78809
Homologene: 53527
Zfp53
Name: zinc finger protein 53
Synonyms: zfas8, KRAZ1, Zfp-53, Zfp118, D030067O06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 24132
VEGA: 17
Homologene: 135946
Vmn2r63
Name: vomeronasal 2, receptor 63
Synonyms: EG435975
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 435975
Homologene: 104832
Ntn4
Name: netrin 4
Synonyms: beta-netrin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 57764
Homologene: 10934
Igfn1
Name: immunoglobulin-like and fibronectin type III domain containing 1
Synonyms: 9830123M21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226438
Homologene: 130054
Vmn2r52
Name: vomeronasal 2, receptor 52
Synonyms: EG384534
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 384534
Homologene: 129605
Mdga1
Name: MAM domain containing glycosylphosphatidylinositol anchor 1
Synonyms: 1200011I03Rik, Mamdc3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 74762
Homologene: 17780
Zfp422
Name: zinc finger protein 422
Synonyms: KOX15, Krox-26, Krox26, Krox25, 2900028O21Rik, Krox-25-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 67255
Homologene: 5067
Cadps2
Name: Ca2+-dependent activator protein for secretion 2
Synonyms: cpd2, A230044C21Rik, Caps2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 320405
Homologene: 23060
Polr1e
Name: polymerase (RNA) I polypeptide E
Synonyms: 53kDa, D030019D19Rik, Paf53, Praf1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 64424
Homologene: 41486
Agbl4
Name: ATP/GTP binding protein-like 4
Synonyms: 4930578N11Rik, 4931433A01Rik, Ccp6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 78933
Homologene: 84880
Stat5b
Name: signal transducer and activator of transcription 5B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20851
Homologene: 55718
BC049715
Name: cDNA sequence BC049715
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 320135
Homologene: 52193
Edem2
Name: ER degradation enhancer, mannosidase alpha-like 2
Synonyms: 9530090G24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 108687
Homologene: 10075
Zfp707
Name: zinc finger protein 707
Synonyms: 1500031N24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 69020
Homologene: 18364
Cd84
Name: CD84 antigen
Synonyms: CDw84, SLAMF5, A130013D22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12523
HGNC: HGNC:1704
Homologene: 48249
2410137M14Rik
Name: RIKEN cDNA 2410137M14 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 76797
Acd
Name: adrenocortical dysplasia
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 497652
Homologene: 23391
Smr2
Name: submaxillary gland androgen regulated protein 2
Synonyms: MSG2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 20600
Vps45
Name: vacuolar protein sorting 45
Synonyms: mVps45
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 22365
Homologene: 5250
Med24
Name: mediator complex subunit 24
Synonyms: Trap100, D11Ertd307e, R75526, 100kDa, DRIP100, Gse2, Pparb2, Thrap4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 23989
Homologene: 40795
Clrn2
Name: clarin 2
Synonyms: EG624224, mpc169H
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 624224
Homologene: 84057
Gm20775
Name: predicted gene, 20775
Type: Gene
Species: Mus musculus (mouse)
Chromosome: Y
NCBI: 665550
Irgq
Name: immunity-related GTPase family, Q
Synonyms: FKSG27
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 210146
Homologene: 17696
Spata31d1b
Name: spermatogenesis associated 31 subfamily D, member 1B
Synonyms: Gm4934, Fam75d1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 238662
VEGA: 13
C1rb
Name: complement component 1, r subcomponent B
Synonyms: mC1rB, Gm8551
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 667277
HGNC: HGNC:1246
Homologene: 1313
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 11,068,020 bp
  • T to A, chromosome 1 at 135,967,357 bp
  • A to G, chromosome 1 at 171,852,121 bp
  • G to A, chromosome 2 at 34,597,422 bp
  • G to A, chromosome 2 at 153,320,368 bp
  • G to A, chromosome 2 at 154,645,866 bp
  • A to G, chromosome 2 at 155,728,993 bp
  • A to C, chromosome 3 at 88,326,013 bp
  • A to C, chromosome 3 at 96,046,413 bp
  • TCCTCGACCT to TCCT, chromosome 3 at 103,056,369 bp
  • T to A, chromosome 4 at 45,024,482 bp
  • T to C, chromosome 4 at 110,955,637 bp
  • A to T, chromosome 4 at 120,713,094 bp
  • G to A, chromosome 5 at 32,289,852 bp
  • T to C, chromosome 5 at 45,454,004 bp
  • T to A, chromosome 5 at 86,822,845 bp
  • T to G, chromosome 5 at 88,098,430 bp
  • A to G, chromosome 5 at 124,819,344 bp
  • A to G, chromosome 5 at 134,383,896 bp
  • A to G, chromosome 5 at 150,431,793 bp
  • C to T, chromosome 6 at 23,688,860 bp
  • A to G, chromosome 6 at 115,960,855 bp
  • A to T, chromosome 6 at 116,626,662 bp
  • A to T, chromosome 6 at 124,574,949 bp
  • A to T, chromosome 6 at 136,839,929 bp
  • G to A, chromosome 6 at 141,909,009 bp
  • T to A, chromosome 7 at 10,159,242 bp
  • T to A, chromosome 7 at 24,534,045 bp
  • C to A, chromosome 7 at 24,570,480 bp
  • A to G, chromosome 7 at 27,565,645 bp
  • C to T, chromosome 7 at 30,771,242 bp
  • A to T, chromosome 7 at 42,926,890 bp
  • C to A, chromosome 8 at 104,257,435 bp
  • A to G, chromosome 8 at 105,698,290 bp
  • A to G, chromosome 8 at 112,773,721 bp
  • T to A, chromosome 9 at 31,329,941 bp
  • G to A, chromosome 9 at 57,086,742 bp
  • G to T, chromosome 9 at 67,331,733 bp
  • T to A, chromosome 10 at 52,096,175 bp
  • C to T, chromosome 10 at 93,644,500 bp
  • A to G, chromosome 11 at 86,256,209 bp
  • A to G, chromosome 11 at 86,298,577 bp
  • T to G, chromosome 11 at 97,349,784 bp
  • C to T, chromosome 11 at 98,710,442 bp
  • G to T, chromosome 11 at 100,790,797 bp
  • A to G, chromosome 12 at 52,518,703 bp
  • A to T, chromosome 13 at 52,632,927 bp
  • C to T, chromosome 13 at 59,715,721 bp
  • G to A, chromosome 13 at 100,425,621 bp
  • A to T, chromosome 14 at 54,679,228 bp
  • A to G, chromosome 14 at 76,416,988 bp
  • T to C, chromosome 15 at 48,314,068 bp
  • C to T, chromosome 15 at 75,973,151 bp
  • T to C, chromosome 15 at 78,285,290 bp
  • T to C, chromosome 16 at 4,849,672 bp
  • A to T, chromosome 16 at 14,201,083 bp
  • A to G, chromosome 16 at 24,661,680 bp
  • T to A, chromosome 17 at 21,505,001 bp
  • T to C, chromosome 17 at 29,842,154 bp
  • T to A, chromosome 17 at 36,978,854 bp
  • A to G, chromosome 17 at 56,190,030 bp
  • T to A, chromosome 18 at 66,859,488 bp
  • T to A, chromosome 18 at 67,648,922 bp
  • A to T, chromosome 19 at 3,261,589 bp
  • T to C, chromosome Y at 10,641,885 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4806 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
042425-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.