Strain Name:
C57BL/6J-MtgxR4947Btlr/Mmmh
Stock Number:
042544-MU
Citation ID:
RRID:MMRRC_042544-MU
Other Names:
R4947 (G1), C57BL/6J-MtgxR4947Btlr
Major Collection:

Gene Information

Myo5a
Name: myosin VA
Synonyms: MVa, MyoVA, Myo5, flail, 9630007J19Rik, Dbv
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 17918
HGNC: HGNC:7602
Homologene: 20100
Acvr1c
Name: activin A receptor, type IC
Synonyms: ALK7, Alk-7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 269275
Homologene: 26724
Grm1
Name: glutamate receptor, metabotropic 1
Synonyms: mGluR1, Grm1, Gprc1a, nmf373, rcw, 4930455H15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 14816
HGNC: HGNC:4593
Homologene: 649
D630045J12Rik
Name: RIKEN cDNA D630045J12 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 330286
Homologene: 19782
Unc93b1
Name: unc-93 homolog B1, TLR signaling regulator
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 54445
Homologene: 41325
Strn
Name: striatin, calmodulin binding protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 268980
Homologene: 2380
Ctbp2
Name: C-terminal binding protein 2
Synonyms: D7Ertd45e, Ribeye, Gtrgeo6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 13017
HGNC: HGNC:2495
Homologene: 75187
Phf20
Name: PHD finger protein 20
Synonyms: 6820402O20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228829
Homologene: 9507
Mif4gd
Name: MIF4G domain containing
Synonyms: 1110014L05Rik, 2310075G12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 69674
Homologene: 41389
Cyp11b2
Name: cytochrome P450, family 11, subfamily b, polypeptide 2
Synonyms: aldosterone synthase, Cyp11b-2, Cyp11b, steroid-11-beta-hydroxylase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 13072
Homologene: 128035
Thbs3
Name: thrombospondin 3
Synonyms: Thbs-3, TSP3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 21827
Homologene: 5159
Mcmbp
Name: minichromosome maintenance complex binding protein
Synonyms: 1110007A13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 210711
Homologene: 11749
Zfp532
Name: zinc finger protein 532
Synonyms: C530030I18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 328977
Homologene: 138627
Kdm5a
Name: lysine (K)-specific demethylase 5A
Synonyms: RBP2, Rbbp2, Jarid1a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 214899
HGNC: HGNC:9886
Homologene: 3419
Zc3h14
Name: zinc finger CCCH type containing 14
Synonyms: 1700016A15Rik, 1010001P15Rik, 2700069A02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 75553
VEGA: 12
Homologene: 32605
Tacc2
Name: transforming, acidic coiled-coil containing protein 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 57752
Homologene: 5087
Cdk5rap2
Name: CDK5 regulatory subunit associated protein 2
Synonyms: 2900018K03Rik, an
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 214444
Homologene: 49533
2310057M21Rik
Name: RIKEN cDNA 2310057M21 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 68277
Homologene: 11793
Polr3a
Name: polymerase (RNA) III (DNA directed) polypeptide A
Synonyms: RPC155, RPC1, 9330175N20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 218832
VEGA: 14
Homologene: 5124
Pid1
Name: phosphotyrosine interaction domain containing 1
Synonyms: 5033414K04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 98496
Homologene: 9924
Nbr1
Name: NBR1, autophagy cargo receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 17966
HGNC: HGNC:6746
Homologene: 7438
Lrpprc
Name: leucine-rich PPR-motif containing
Synonyms: Lrp130, 3110001K13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 72416
Homologene: 32695
Frem1
Name: Fras1 related extracellular matrix protein 1
Synonyms: eyem02Jus, heb, QBRICK, eyes2, crf11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 329872
Homologene: 27049
Prokr2
Name: prokineticin receptor 2
Synonyms: PKR2, B830005M06Rik, EG-VEGRF2, Gpr73l1, Gpcr73l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 246313
Homologene: 16368
Ms4a4b
Name: membrane-spanning 4-domains, subfamily A, member 4B
Synonyms: Chandra, Ly116
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 60361
Homologene: 113790
Mta2
Name: metastasis-associated gene family, member 2
Synonyms: mmta2, Mta1l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 23942
HGNC: HGNC:7411
Homologene: 3480
Copg1
Name: coatomer protein complex, subunit gamma 1
Synonyms: D6Ertd71e, D6Wsu16e, Copg
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 54161
HGNC: HGNC:2236
Homologene: 56745
Timm50
Name: translocase of inner mitochondrial membrane 50
Synonyms: TIM50L, 2810403L02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 66525
Homologene: 57031
Lrrc40
Name: leucine rich repeat containing 40
Synonyms: 2610040E16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 67144
Homologene: 9825
Fmnl2
Name: formin-like 2
Synonyms: 5430425K04Rik, man
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 71409
Homologene: 70871
Ibtk
Name: inhibitor of Bruton agammaglobulinemia tyrosine kinase
Synonyms: 5430411K16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 108837
Homologene: 34661
Serinc1
Name: serine incorporator 1
Synonyms: TMS-2, 1500011D18Rik, Tde1l, Tde2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 56442
Homologene: 41334
Pcgf3
Name: polycomb group ring finger 3
Synonyms: D630042K08Rik, RNF3A, DONG1, 2310035N15Rik, Rnf3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 69587
Homologene: 4605
Bcl2a1a
Name: B cell leukemia/lymphoma 2 related protein A1a
Synonyms: A1, Bfl-1, Bcl2a1, Hbpa1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12044
HGNC: HGNC:991
Homologene: 2988
Tbkbp1
Name: TBK1 binding protein 1
Synonyms: 3110043L15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 73174
Homologene: 8820
Nos3
Name: nitric oxide synthase 3, endothelial cell
Synonyms: eNOS, ecNOS, Nos-3, 2310065A03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 18127
HGNC: HGNC:7876
Homologene: 504
Dnah5
Name: dynein, axonemal, heavy chain 5
Synonyms: Mdnah5, b2b1154Clo, b2b1134Clo, b2b1537Clo, b2b1565Clo, Dnahc5, b2b3491Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 110082
HGNC: HGNC:2950
Homologene: 1048
Pcdh7
Name: protocadherin 7
Synonyms: BH-protocadherin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 54216
HGNC: HGNC:8659
Homologene: 36101
Wdr11
Name: WD repeat domain 11
Synonyms: 2900055P10Rik, Wdr11, Brwd2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 207425
Homologene: 41229
Vmn2r57
Name: vomeronasal 2, receptor 57
Synonyms: EG269902
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 269902
Homologene: 104832
Sntg1
Name: syntrophin, gamma 1
Synonyms: G1SYN, SYN4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 71096
Homologene: 56834
Olfr109
Name: olfactory receptor 109
Synonyms: MOR250-1, GA_x6K02T2PSCP-1914078-1915022
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 258832
Homologene: 12811
Me3
Name: malic enzyme 3, NADP(+)-dependent, mitochondrial
Synonyms: B230207H15Rik, 1700020C08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 109264
HGNC: HGNC:6985
Homologene: 100773
H2-Q3
Name: histocompatibility 2, Q region locus 3
Synonyms: Qa3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 625285
Olfr186
Name: olfactory receptor 186
Synonyms: GA_x54KRFPKG5P-55257214-55256285, MOR183-9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 258318
Homologene: 133671
Lamtor3
Name: late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
Synonyms: MEK binding partner 1, Mp1, Map2k1ip1, Mapksp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 56692
Homologene: 10539
C130026I21Rik
Name: RIKEN cDNA C130026I21 gene
Synonyms: OTTMUSG00000029174
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 620078
Homologene: 131208
Vmn2r80
Name: vomeronasal 2, receptor 80
Synonyms: EG624765
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 624765
Homologene: 83483
Evpl
Name: envoplakin
Synonyms: 210kDa protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 14027
HGNC: HGNC:3503
Homologene: 1506
Upk3bl
Name: uroplakin 3B-like
Synonyms: 2310043J07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 69665
Homologene: 78581
Olfr376
Name: olfactory receptor 376
Synonyms: GA_x6K02T2P1NL-3535075-3536028, MOR135-12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 258924
Homologene: 133579
D630003M21Rik
Name: RIKEN cDNA D630003M21 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228846
Homologene: 18598
Gtdc1
Name: glycosyltransferase-like domain containing 1
Synonyms: E330008O22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227835
Homologene: 32590
Wiz
Name: widely-interspaced zinc finger motifs
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 22404
Homologene: 7997
Cstdc6
Name: cystatin domain containing 6
Synonyms: Gm1975, BC117090
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 100038854
VEGA: 16
HGNC: HGNC:2481
Homologene: 104045
Fcgbp
Name: Fc fragment of IgG binding protein
Synonyms: A430096B05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 215384
Homologene: 68369
Vmn2r112
Name: vomeronasal 2, receptor 112
Synonyms: EG628185
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 628185
Homologene: 86604
Gm14226
Name: predicted gene 14226
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Gm16332
Name: predicted gene 16332
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 100417200
Fez1
Name: fasciculation and elongation protein zeta 1 (zygin I)
Synonyms: UNC-76, UNC76
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235180
HGNC: HGNC:3659
Homologene: 21063
Olfr669
Name: olfactory receptor 669
Synonyms: GA_x6K02T2PBJ9-7567376-7568329, MOR34-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259045
Homologene: 72057
Rnf141
Name: ring finger protein 141
Synonyms: ZNF230, ZFP36, 2610110L04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 67150
Homologene: 9503
Skint11
Name: selection and upkeep of intraepithelial T cells 11
Synonyms: A630098G03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230623
Homologene: 136292
Tmem132a
Name: transmembrane protein 132A
Synonyms: 6720481D13Rik, Hspa5bp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 98170
Homologene: 75076
Flacc1
Name: flagellum associated containing coiled-coil domains 1
Synonyms: 4933405P16Rik, 4933425F06Rik, Als2cr12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 108812
Homologene: 51399
Tas2r139
Name: taste receptor, type 2, member 139
Synonyms: mt2r34, Tas2r39
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 353148
Homologene: 52214
Gm9871
Name: predicted gene 9871
Synonyms: EG207157
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 207157
Donson
Name: downstream neighbor of SON
Synonyms: Donson, 1110025J21Rik, ORF60
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 60364
HGNC: HGNC:2993
Homologene: 32350
Ocln
Name: occludin
Synonyms: Ocl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 18260
HGNC: HGNC:8104
Homologene: 1905
Maml3
Name: mastermind like transcriptional coactivator 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 433586
Homologene: 41284
Slc22a28
Name: solute carrier family 22, member 28
Synonyms: Gm5631
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 434674
VEGA: 19
Homologene: 77136
Ifi204
Name: interferon activated gene 204
Synonyms: p204
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 15951
HGNC: HGNC:5395
Homologene: 115929
Kcnn1
Name: potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
Synonyms: SK1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 84036
HGNC: HGNC:6290
Homologene: 37595
Keap1
Name: kelch-like ECH-associated protein 1
Synonyms: ring canal protein, INrf2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 50868
Homologene: 8184
Crb2
Name: crumbs family member 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241324
Homologene: 45474
Mlana
Name: melan-A
Synonyms: Mart1, A930034P04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 77836
VEGA: 19
HGNC: HGNC:7124
Homologene: 4026
Gm10754
Name: predicted gene 10754
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 100038699
VEGA: 10
Mpnd
Name: MPN domain containing
Synonyms: E130307M08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 68047
Homologene: 12231
Gm12680
Name: predicted gene 12680
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Lat
Name: linker for activation of T cells
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 16797
Homologene: 7811
Gm20528
Name: predicted gene 20528
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Gm9866
Name: predicted gene 9866
Synonyms: EG636791
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 636791
Gm21718
Name: predicted gene, 21718
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Zfp729b
Name: zinc finger protein 729b
Synonyms: AA987161
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 100416706
Homologene: 133713
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to A, chromosome 1 at 8,782,798 bp
  • T to A, chromosome 1 at 58,676,539 bp
  • A to T, chromosome 1 at 84,038,260 bp
  • G to A, chromosome 1 at 85,112,482 bp
  • CAGAGAGAGAGAGA to CAGAGAGAGAGA, chromosome 1 at 88,211,984 bp
  • G to A, chromosome 1 at 139,865,992 bp
  • A to G, chromosome 1 at 173,755,750 bp
  • C to T, chromosome 2 at 37,795,331 bp
  • T to C, chromosome 2 at 44,591,956 bp
  • T to G, chromosome 2 at 53,073,710 bp
  • T to A, chromosome 2 at 58,315,975 bp
  • T to C, chromosome 2 at 132,373,653 bp
  • A to T, chromosome 2 at 155,024,959 bp
  • T to C, chromosome 2 at 156,254,270 bp
  • T to A, chromosome 2 at 158,186,196 bp
  • A to G, chromosome 3 at 51,856,539 bp
  • T to C, chromosome 3 at 89,226,431 bp
  • T to A, chromosome 3 at 137,925,109 bp
  • A to G, chromosome 3 at 158,063,835 bp
  • A to G, chromosome 4 at 70,228,592 bp
  • A to G, chromosome 4 at 82,966,134 bp
  • A to T, chromosome 4 at 85,764,800 bp
  • T to C, chromosome 4 at 114,191,510 bp
  • G to A, chromosome 5 at 24,377,855 bp
  • A to G, chromosome 5 at 57,721,916 bp
  • T to C, chromosome 5 at 108,487,961 bp
  • T to C, chromosome 5 at 136,057,245 bp
  • C to T, chromosome 6 at 38,148,543 bp
  • A to G, chromosome 6 at 42,141,566 bp
  • C to A, chromosome 6 at 87,903,473 bp
  • A to G, chromosome 6 at 101,796,773 bp
  • T to C, chromosome 6 at 120,402,559 bp
  • A to G, chromosome 7 at 28,089,812 bp
  • G to T, chromosome 7 at 28,310,044 bp
  • A to T, chromosome 7 at 41,400,495 bp
  • A to G, chromosome 7 at 89,633,014 bp
  • A to G, chromosome 7 at 104,938,742 bp
  • T to C, chromosome 7 at 110,825,320 bp
  • A to G, chromosome 7 at 126,367,938 bp
  • A to T, chromosome 7 at 128,712,696 bp
  • T to A, chromosome 7 at 129,616,604 bp
  • A to T, chromosome 7 at 130,625,899 bp
  • T to A, chromosome 7 at 131,357,614 bp
  • C to A, chromosome 7 at 132,999,283 bp
  • C to A, chromosome 8 at 70,844,429 bp
  • T to G, chromosome 9 at 21,237,553 bp
  • A to C, chromosome 9 at 36,868,875 bp
  • A to G, chromosome 9 at 75,123,048 bp
  • T to C, chromosome 9 at 85,710,412 bp
  • G to A, chromosome 9 at 88,957,282 bp
  • A to G, chromosome 10 at 10,782,633 bp
  • T to C, chromosome 10 at 57,523,045 bp
  • T to G, chromosome 10 at 79,194,698 bp
  • A to T, chromosome 10 at 97,682,148 bp
  • C to T, chromosome 11 at 73,375,417 bp
  • T to C, chromosome 11 at 97,138,944 bp
  • T to C, chromosome 11 at 101,575,077 bp
  • C to A, chromosome 11 at 115,609,637 bp
  • T to C, chromosome 11 at 116,223,375 bp
  • A to T, chromosome 12 at 27,160,228 bp
  • A to G, chromosome 12 at 98,759,824 bp
  • T to C, chromosome 13 at 67,596,672 bp
  • T to C, chromosome 13 at 100,539,715 bp
  • A to C, chromosome 14 at 24,482,464 bp
  • T to A, chromosome 14 at 51,315,959 bp
  • T to A, chromosome 15 at 28,272,372 bp
  • T to C, chromosome 15 at 74,851,570 bp
  • T to C, chromosome 16 at 36,321,765 bp
  • A to G, chromosome 16 at 59,027,445 bp
  • A to T, chromosome 16 at 91,682,551 bp
  • T to A, chromosome 17 at 22,602,879 bp
  • A to G, chromosome 17 at 32,368,083 bp
  • T to A, chromosome 17 at 35,359,732 bp
  • T to C, chromosome 17 at 37,466,743 bp
  • T to A, chromosome 17 at 56,010,268 bp
  • T to C, chromosome 17 at 78,661,779 bp
  • A to T, chromosome 17 at 84,771,538 bp
  • T to C, chromosome 18 at 65,625,066 bp
  • C to A, chromosome 19 at 3,935,871 bp
  • T to C, chromosome 19 at 8,131,452 bp
  • T to C, chromosome 19 at 8,946,291 bp
  • T to C, chromosome 19 at 10,866,934 bp
  • T to C, chromosome 19 at 11,454,737 bp
  • T to C, chromosome 19 at 29,700,151 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
(Deceased) Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4947 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
042544-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.