Strain Name:
C57BL/6J-MtgxR4968Btlr/Mmmh
Stock Number:
042564-MU
Citation ID:
RRID:MMRRC_042564-MU
Other Names:
R4968 (G1), C57BL/6J-MtgxR4968Btlr
Major Collection:

Gene Information

Myo10
Name: myosin X
Synonyms: D15Ertd600e, myosin-X
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 17909
HGNC: HGNC:7593
Homologene: 36328
B4galt6
Name: UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 56386
VEGA: 18
HGNC: HGNC:929
Homologene: 3506
Lmf1
Name: lipase maturation factor 1
Synonyms: Tmem112, 2400010G15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 76483
Homologene: 23384
Snx1
Name: sorting nexin 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 56440
Homologene: 99716
Thbs4
Name: thrombospondin 4
Synonyms: TSP-4, TSP4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 21828
Homologene: 20691
Mtss1
Name: MTSS I-BAR domain containing 1
Synonyms: MIM, 2310003N14Rik, D130001D01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 211401
VEGA: 15
Homologene: 8841
Lpp
Name: LIM domain containing preferred translocation partner in lipoma
Synonyms: B130055L10Rik, 9430020K16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 210126
VEGA: 16
HGNC: HGNC:6679
Homologene: 4075
Hsp90ab1
Name: heat shock protein 90 alpha (cytosolic), class B member 1
Synonyms: Hspcb, Hsp90, C81438, Hsp84-1, Hsp84
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 15516
HGNC: HGNC:5258
Homologene: 74306
Ttc30b
Name: tetratricopeptide repeat domain 30B
Synonyms: 2510042P03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 72421
Homologene: 71716
Cyp11b2
Name: cytochrome P450, family 11, subfamily b, polypeptide 2
Synonyms: aldosterone synthase, steroid-11-beta-hydroxylase, Cyp11b, Cyp11b-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 13072
Homologene: 128035
Neurl4
Name: neuralized E3 ubiquitin protein ligase 4
Synonyms: 0610025P10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216860
Homologene: 13029
Myh10
Name: myosin, heavy polypeptide 10, non-muscle
Synonyms: Fltn, nonmuscle myosin heavy chain IIB, 5730504C04Rik, nonmuscle myosin heavy chain II-B, Myosin IIB, 9330167F11Rik, NMHC II-B, NMHC-B, Myhn2, SMemb, myosin IIB, Myhn-2, Fltn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 77579
HGNC: HGNC:7568
Homologene: 55941
Triobp
Name: TRIO and F-actin binding protein
Synonyms: Mus EST 478828, Tara, EST478828
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 110253
Homologene: 5104
Btaf1
Name: B-TFIID TATA-box binding protein associated factor 1
Synonyms: E430027O22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 107182
Homologene: 31978
Ddx5
Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 5
Synonyms: p68, 2600009A06Rik, Hlr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 13207
HGNC: HGNC:2746
Homologene: 6797
Nsf
Name: N-ethylmaleimide sensitive fusion protein
Synonyms: N-ethylmaleimide sensitive factor, SKD2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 18195
HGNC: HGNC:8016
Homologene: 4502
Tpr
Name: translocated promoter region, nuclear basket protein
Synonyms: 2610029M07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 108989
Homologene: 37753
Nup133
Name: nucleoporin 133
Synonyms: 4832420O05Rik, mermaid
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234865
Homologene: 32402
Mphosph10
Name: M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
Synonyms: 2810453H10Rik, 5730405D16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 67973
HGNC: HGNC:7213
Homologene: 134741
Ccdc34
Name: coiled-coil domain containing 34
Synonyms: 2810027O19Rik, 4930522P10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 68201
Homologene: 12245
Syngr2
Name: synaptogyrin 2
Synonyms: Clast2, cellugyrin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20973
Homologene: 20987
Iars2
Name: isoleucine-tRNA synthetase 2, mitochondrial
Synonyms: 2010002H18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 381314
Homologene: 7118
Atp5b
Name: ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 11947
HGNC: HGNC:830
Homologene: 1273
2810021J22Rik
Name: RIKEN cDNA 2810021J22 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 69944
Homologene: 138400
Enpp6
Name: ectonucleotide pyrophosphatase/phosphodiesterase 6
Synonyms: D8Ertd514e, 4833421B01Rik, B830047L21Rik, Npp6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 320981
Homologene: 62657
Cdh19
Name: cadherin 19, type 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227485
HGNC: HGNC:1758
Homologene: 23286
Sptbn2
Name: spectrin beta, non-erythrocytic 2
Synonyms: Spnb3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 20743
VEGA: 19
Homologene: 48482
Septin10
Name: septin 10
Synonyms: Sept10, 4921515A04Rik, 9430099J10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 103080
VEGA: 10
Homologene: 27035
Rufy1
Name: RUN and FYVE domain containing 1
Synonyms: 3000002E04Rik, ZFYVE12, Rabip4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216724
Homologene: 23522
Zswim4
Name: zinc finger SWIM-type containing 4
Synonyms: E130119J17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 212168
Homologene: 18183
Lrrc8c
Name: leucine rich repeat containing 8 family, member C
Synonyms: E430036I04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100604
Homologene: 12997
Zfp280b
Name: zinc finger protein 280B
Synonyms: Suhw2, D10Jhu82e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 64453
VEGA: 10
Homologene: 62794
Selenok
Name: selenoprotein K
Synonyms: Selk, 30kDa, HSPC030
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 80795
Homologene: 56870
Nlrc4
Name: NLR family, CARD domain containing 4
Synonyms: Card12, 9530011P19Rik, Ipaf
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 268973
VEGA: 17
Homologene: 10924
Hmcn1
Name: hemicentin 1
Synonyms: EG545370, LOC240793
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 545370
Homologene: 23741
Piezo2
Name: piezo-type mechanosensitive ion channel component 2
Synonyms: 9430028L06Rik, Piezo2, Fam38b2, Fam38b, 9030411M15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 667742
Homologene: 49695
Kcp
Name: kielin/chordin-like protein
Synonyms: LOC333088, Crim2, KCP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 333088
Homologene: 87817
Olfr639
Name: olfactory receptor 639
Synonyms: GA_x6K02T2PBJ9-6747143-6746193, MOR12-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259088
Homologene: 17497
Aplnr
Name: apelin receptor
Synonyms: APJ, msr/apj, Agtrl1, apelin receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 23796
HGNC: HGNC:339
Homologene: 3784
Fhad1
Name: forkhead-associated (FHA) phosphopeptide binding domain 1
Synonyms: 2900090M10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 329977
Homologene: 77947
Lrp1b
Name: low density lipoprotein-related protein 1B
Synonyms: 9630004P12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 94217
HGNC: HGNC:6693
Homologene: 56810
Vmn2r61
Name: vomeronasal 2, receptor 61
Synonyms: Casr-rs2, Gprc2a-rs2, EG637873
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 637873
Homologene: 129683
Tuba8
Name: tubulin, alpha 8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 53857
Homologene: 56766
Deup1
Name: deuterosome assembly protein 1
Synonyms: Ccdc67, 4933401K09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 234964
Homologene: 18760
Alpi
Name: alkaline phosphatase, intestinal
Synonyms: 2010001C14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 76768
Homologene: 122414
Ahnak
Name: AHNAK nucleoprotein (desmoyokin)
Synonyms: DY6, 1110004P15Rik, 2310047C17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 66395
VEGA: 19
HGNC: HGNC:347
Homologene: 67425
Slfn10-ps
Name: schlafen 10, pseudogene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237887
Ripor3
Name: RIPOR family member 3
Synonyms: Fam65c, 2310033K02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 69553
Homologene: 15438
Pxdn
Name: peroxidasin
Synonyms: VPO1, 2310075M15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 69675
Homologene: 33907
Pign
Name: phosphatidylinositol glycan anchor biosynthesis, class N
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 27392
HGNC: HGNC:8967
Homologene: 6330
St6galnac6
Name: ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
Synonyms: Siat7f, ST6GalNAcVI
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 50935
Homologene: 8390
Pla2r1
Name: phospholipase A2 receptor 1
Synonyms: PLA2-I receptor, Pla2g1br, M-type receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 18779
HGNC: HGNC:9042
Homologene: 32016
Cep89
Name: centrosomal protein 89
Synonyms: 2610507L03Rik, Ccdc123
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 72140
Homologene: 12444
Ccdc36
Name: coiled-coil domain containing 36
Synonyms: Iho1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 434438
Homologene: 52256
Dcbld2
Name: discoidin, CUB and LCCL domain containing 2
Synonyms: 1700055P21Rik, Esdn, CLCP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 73379
Homologene: 12499
Vwa5b2
Name: von Willebrand factor A domain containing 5B2
Synonyms: EG328644
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 328643
Homologene: 28056
F11
Name: coagulation factor XI
Synonyms: 1600027G01Rik, Cf11, FXI, plasma thromboplastin antecedent
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 109821
HGNC: HGNC:3529
Homologene: 86654
Arhgap9
Name: Rho GTPase activating protein 9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216445
VEGA: 10
Homologene: 13041
Prob1
Name: proline rich basic protein 1
Synonyms: Gm1614, LOC381148
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 381148
Homologene: 83773
P3h2
Name: prolyl 3-hydroxylase 2
Synonyms: Leprel1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 210530
Homologene: 10062
Lcmt2
Name: leucine carboxyl methyltransferase 2
Synonyms: Tyw4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 329504
Homologene: 19642
4921513D11Rik
Name: RIKEN cDNA 4921513D11 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Selplg
Name: selectin, platelet (p-selectin) ligand
Synonyms: Psgl-1, CD162, Psgl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 20345
Homologene: 2261
Ikbke
Name: inhibitor of kappaB kinase epsilon
Synonyms: IKK-i, IKKepsilon
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 56489
Homologene: 23168
Lrfn5
Name: leucine rich repeat and fibronectin type III domain containing 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 238205
Homologene: 17582
Ace
Name: angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
Synonyms: CD143
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 11421
HGNC: HGNC:2707
Homologene: 37351
Bco1
Name: beta-carotene oxygenase 1
Synonyms: Bcdo, Bcmo1, beta-CD, betaCMOOX, Bcdo1, Cmoi
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 63857
Homologene: 41172
Kcnk10
Name: potassium channel, subfamily K, member 10
Synonyms: 1700024D23Rik, 3010005K24Rik, Trek2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 72258
VEGA: 12
HGNC: HGNC:6273
Homologene: 11321
Cyp21a1
Name: cytochrome P450, family 21, subfamily a, polypeptide 1
Synonyms: 21OH, Oh21-1, 21-OH, Oh21-1, 21-hydroxylase, Cyp21, 21OHA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 13079
Homologene: 68063
Mpp2
Name: membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
Synonyms: D11Bwg0652e, Dlgh2, Dlg2, Pals4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 50997
HGNC: HGNC:7220
Homologene: 3920
Fhit
Name: fragile histidine triad gene
Synonyms: Fra14A2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 14198
HGNC: HGNC:3701
Homologene: 21661
Asah1
Name: N-acylsphingosine amidohydrolase 1
Synonyms: acid ceramidase, 2310081N20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 11886
HGNC: HGNC:735
Homologene: 10504
Anks6
Name: ankyrin repeat and sterile alpha motif domain containing 6
Synonyms: 2210417J20Rik, b2b1801.1Clo, LOC269533, SamCystin, Samd6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 75691
Homologene: 19545
N4bp2l2
Name: NEDD4 binding protein 2-like 2
Synonyms: zag1, 2700092H06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 381695
Homologene: 115380
Grtp1
Name: GH regulated TBC protein 1
Synonyms: 5430401C05Rik, Tbc1d6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 66790
Homologene: 84592
Olfr1386
Name: olfactory receptor 1386
Synonyms: GA_x6K02T2QP88-5964781-5963852, MOR256-50
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 257888
Homologene: 86692
Gjb5
Name: gap junction protein, beta 5
Synonyms: Gjb-5, Cnx31.1, Cx31.1, connexin 31.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 14622
HGNC: HGNC:4287
Homologene: 3858
Rpl27a-ps1
Name: ribosomal protein L27A, pseudogene 1
Synonyms: Gm4923
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 237361
VEGA: 10
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 87,101,525 bp
  • A to T, chromosome 1 at 105,646,858 bp
  • T to C, chromosome 1 at 110,925,228 bp
  • GCC to G, chromosome 1 at 131,275,267 bp
  • A to G, chromosome 1 at 150,393,555 bp
  • A to G, chromosome 1 at 150,657,470 bp
  • G to A, chromosome 1 at 185,323,072 bp
  • C to T, chromosome 2 at 32,608,086 bp
  • T to C, chromosome 2 at 40,702,707 bp
  • C to T, chromosome 2 at 41,789,062 bp
  • C to T, chromosome 2 at 60,420,314 bp
  • T to C, chromosome 2 at 75,938,047 bp
  • T to C, chromosome 2 at 85,136,945 bp
  • G to T, chromosome 2 at 110,040,733 bp
  • T to C, chromosome 2 at 121,139,736 bp
  • T to C, chromosome 2 at 167,985,117 bp
  • C to T, chromosome 4 at 47,030,795 bp
  • A to T, chromosome 4 at 127,356,222 bp
  • C to A, chromosome 4 at 141,918,307 bp
  • A to G, chromosome 5 at 105,607,127 bp
  • T to C, chromosome 5 at 113,819,726 bp
  • A to G, chromosome 5 at 150,661,413 bp
  • A to T, chromosome 6 at 29,497,629 bp
  • T to A, chromosome 6 at 121,220,589 bp
  • A to G, chromosome 7 at 35,409,630 bp
  • A to G, chromosome 7 at 42,300,054 bp
  • A to G, chromosome 7 at 64,382,908 bp
  • T to C, chromosome 7 at 104,012,570 bp
  • A to T, chromosome 8 at 13,192,184 bp
  • A to G, chromosome 8 at 41,354,030 bp
  • G to A, chromosome 8 at 45,245,733 bp
  • A to G, chromosome 8 at 47,065,848 bp
  • A to T, chromosome 8 at 84,217,372 bp
  • A to T, chromosome 8 at 117,131,094 bp
  • A to T, chromosome 8 at 123,915,196 bp
  • T to C, chromosome 9 at 15,592,428 bp
  • T to A, chromosome 9 at 66,094,342 bp
  • C to T, chromosome 9 at 108,412,514 bp
  • A to G, chromosome 10 at 59,181,121 bp
  • A to G, chromosome 10 at 61,310,127 bp
  • G to T, chromosome 10 at 76,039,354 bp
  • G to A, chromosome 10 at 127,327,006 bp
  • T to C, chromosome 10 at 128,083,987 bp
  • T to C, chromosome 11 at 49,470,531 bp
  • T to A, chromosome 11 at 50,410,607 bp
  • A to T, chromosome 11 at 58,878,790 bp
  • A to G, chromosome 11 at 68,793,223 bp
  • T to C, chromosome 11 at 69,907,308 bp
  • C to T, chromosome 11 at 83,030,381 bp
  • T to C, chromosome 11 at 102,064,298 bp
  • T to C, chromosome 11 at 103,861,871 bp
  • A to G, chromosome 11 at 105,981,853 bp
  • T to C, chromosome 11 at 106,784,127 bp
  • T to C, chromosome 11 at 117,813,470 bp
  • T to A, chromosome 12 at 30,000,012 bp
  • C to A, chromosome 12 at 61,839,675 bp
  • T to C, chromosome 12 at 98,434,902 bp
  • A to G, chromosome 13 at 92,758,068 bp
  • C to T, chromosome 14 at 10,421,522 bp
  • T to A, chromosome 14 at 29,970,107 bp
  • T to C, chromosome 15 at 25,808,184 bp
  • A to G, chromosome 15 at 58,943,918 bp
  • A to T, chromosome 15 at 74,854,005 bp
  • T to A, chromosome 15 at 78,966,616 bp
  • T to C, chromosome 16 at 20,597,212 bp
  • A to G, chromosome 16 at 24,979,314 bp
  • A to G, chromosome 16 at 25,992,662 bp
  • A to G, chromosome 16 at 58,424,711 bp
  • A to G, chromosome 17 at 25,585,618 bp
  • A to G, chromosome 17 at 34,803,409 bp
  • T to C, chromosome 17 at 45,571,036 bp
  • A to G, chromosome 17 at 74,446,941 bp
  • T to C, chromosome 17 at 79,628,222 bp
  • G to T, chromosome 18 at 20,727,969 bp
  • T to C, chromosome 18 at 35,652,552 bp
  • A to T, chromosome 18 at 63,144,971 bp
  • A to T, chromosome 19 at 4,729,202 bp
  • C to A, chromosome 19 at 9,015,100 bp
  • T to A, chromosome 19 at 36,969,951 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4968 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
042564-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.