Strain Name:
C57BL/6J-MtgxR4975Btlr/Mmmh
Stock Number:
042570-MU
Citation ID:
RRID:MMRRC_042570-MU
Other Names:
R4975 (G1), C57BL/6J-MtgxR4975Btlr
Major Collection:

Gene Information

Myh7
Name: myosin, heavy polypeptide 7, cardiac muscle, beta
Synonyms: MYH-beta/slow, MyHC-I, Myhc-b, Myhcb, B-MHC, beta-MHC, betaMHC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 140781
HGNC: HGNC:7577
Homologene: 68044
Snx1
Name: sorting nexin 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 56440
Homologene: 99716
Il21
Name: interleukin 21
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 60505
HGNC: HGNC:6005
Homologene: 11032
Msi2
Name: musashi RNA-binding protein 2
Synonyms: msi2h, Musashi2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 76626
Homologene: 62199
Abcc8
Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 8
Synonyms: SUR1, Sur, D930031B21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 20927
HGNC: HGNC:59
Homologene: 68048
Kansl1
Name: KAT8 regulatory NSL complex subunit 1
Synonyms: 1700081L11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 76719
Homologene: 9140
Setx
Name: senataxin
Synonyms: A930037J23Rik, Als4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 269254
HGNC: HGNC:445
Homologene: 41003
Srrm1
Name: serine/arginine repetitive matrix 1
Synonyms: SRm160
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 51796
Homologene: null
Clasp2
Name: CLIP associating protein 2
Synonyms: CLASP2alpha, 1500004F14Rik, CLASP2, 8030404L10Rik, CLASP2gamma, CLASP2beta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 76499
VEGA: 9
Homologene: 24944
Ralgapb
Name: Ral GTPase activating protein, beta subunit (non-catalytic)
Synonyms: B230339M05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228850
Homologene: 10666
Hectd1
Name: HECT domain E3 ubiquitin protein ligase 1
Synonyms: b2b327Clo, A630086P08Rik, opm
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 207304
VEGA: 12
Homologene: 9115
Zfp619
Name: zinc finger protein 619
Synonyms: 3000002G13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 70227
Homologene: 133818
Tet2
Name: tet methylcytosine dioxygenase 2
Synonyms: Ayu17-449, E130014J05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 214133
Homologene: 49498
Gtf2ird1
Name: general transcription factor II I repeat domain-containing 1
Synonyms: BEN, ESTM9, MusTRD1, Tg(Alb1-Myc)166.8Sst, Alb-c-myc line 166.8, GTF3, Alb/c-myc line 166.8, c-myc line 166.8, WBSCR11, Cream1, binding factor for early enhancer
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 57080
HGNC: HGNC:4661
Homologene: 4158
Rapgef1
Name: Rap guanine nucleotide exchange factor (GEF) 1
Synonyms: Grf2, 4932418O06Rik, C3G
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 107746
HGNC: HGNC:4568
Homologene: 50501
Rttn
Name: rotatin
Synonyms: C530033I08Rik, 4921538A15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 246102
VEGA: 18
Homologene: 65275
Nol6
Name: nucleolar protein family 6 (RNA-associated)
Synonyms: Nrap
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230082
Homologene: 41505
Stk39
Name: serine/threonine kinase 39
Synonyms: Rnl5, SPAK, RF005, DCHT
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 53416
Homologene: 22739
Dmap1
Name: DNA methyltransferase 1-associated protein 1
Synonyms: 1500016M21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 66233
Homologene: 41311
Ccni
Name: cyclin I
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 12453
HGNC: HGNC:1595
Homologene: 4979
Vps8
Name: VPS8 CORVET complex subunit
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 209018
Homologene: 44592
Cpsf2
Name: cleavage and polyadenylation specific factor 2
Synonyms: Cpsf, 100kDa, 2610024B04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 51786
VEGA: 12
HGNC: HGNC:2325
Homologene: 6460
Mia3
Name: melanoma inhibitory activity 3
Synonyms: LOC385255, 9130229H14Rik, Tango, A930039G15Rik, B230399H06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 338366
Homologene: 85165
Lama1
Name: laminin, alpha 1
Synonyms: Lama
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 16772
VEGA: 17
HGNC: HGNC:6481
Homologene: 21146
Dnah8
Name: dynein, axonemal, heavy chain 8
Synonyms: Hst6.7b, P1-Loop, Dnahc8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 13417
VEGA: 17
HGNC: HGNC:2952
Homologene: 1049
Twf2
Name: twinfilin actin binding protein 2
Synonyms: Twf2, Twinfilin-2, Ptk9l, A6-related
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 23999
HGNC: HGNC:9621
Homologene: 5272
Svil
Name: supervillin
Synonyms: B430302E16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 225115
Homologene: 25090
Siglece
Name: sialic acid binding Ig-like lectin E
Synonyms: Siglec5, mSiglec-E, Siglecl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 83382
Homologene: 130669
Lmo2
Name: LIM domain only 2
Synonyms: Rbtn-2, Rhom-2, Rbtn2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 16909
HGNC: HGNC:6642
Homologene: 4072
Hmcn2
Name: hemicentin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 665700
Homologene: 90772
Reln
Name: reelin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 19699
HGNC: HGNC:9957
Homologene: 3699
Olfr648
Name: olfactory receptor 648
Synonyms: GA_x6K02T2PBJ9-6914780-6913830, MOR31-12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 258746
Homologene: 82999
Zfp608
Name: zinc finger protein 608
Synonyms: 4932417D18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 269023
VEGA: 18
Homologene: 18485
Olfr73
Name: olfactory receptor 73
Synonyms: GA_x6K02T2Q125-49527073-49526132, mOR-EG, MOR174-9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 117004
Homologene: 133889
Rab11fip4
Name: RAB11 family interacting protein 4 (class II)
Synonyms: A730072L08Rik, RAB11-FIP4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 268451
Homologene: 8803
Sybu
Name: syntabulin (syntaxin-interacting)
Synonyms: A830027B17Rik, Golsyn/Syntabulin, 5730410E15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 319613
VEGA: 15
Homologene: 9838
Gm6614
Name: predicted gene 6614
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 625716
Homologene: 87075
Tfip11
Name: tuftelin interacting protein 11
Synonyms: Tip39
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 54723
Homologene: 40813
Xylt1
Name: xylosyltransferase 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233781
Homologene: 32534
Otog
Name: otogelin
Synonyms: Otgn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 18419
HGNC: HGNC:8516
Homologene: 8421
Cdsn
Name: corneodesmosin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 386463
HGNC: HGNC:1802
Homologene: null
Chtf18
Name: CTF18, chromosome transmission fidelity factor 18
Synonyms: CTF18, 6030457M03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 214901
Homologene: 32532
Cdkl4
Name: cyclin-dependent kinase-like 4
Synonyms: LOC381113
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 381113
VEGA: 17
Homologene: 28725
Ror2
Name: receptor tyrosine kinase-like orphan receptor 2
Synonyms: Ntrkr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 26564
Homologene: 55831
C130079G13Rik
Name: RIKEN cDNA C130079G13 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229333
HGNC: null
Homologene: null
Cyld
Name: CYLD lysine 63 deubiquitinase
Synonyms: CYLD1, 2900009M21Rik, C130039D01Rik, 2010013M14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 74256
HGNC: HGNC:2584
Homologene: 9069
Ergic3
Name: ERGIC and golgi 3
Synonyms: D2Ucla1, 2310015B14Rik, CGI-54, NY-BR-84, Sdbcag84
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 66366
Homologene: 5289
Med16
Name: mediator complex subunit 16
Synonyms: Thrap5, 95kDa, Trap95
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 216154
Homologene: 64602
Disp3
Name: dispatched RND transporter family member 3
Synonyms: Ptchd2, G630052C06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 242748
Homologene: 25712
Cttnbp2
Name: cortactin binding protein 2
Synonyms: ORF4, 3010022N24Rik, Cortbp2, 9130022E09Rik, 4732477G22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 30785
Homologene: 14125
4930452B06Rik
Name: RIKEN cDNA 4930452B06 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 74430
Homologene: 18873
Rgs22
Name: regulator of G-protein signalling 22
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 626596
Homologene: 75047
Tmc1
Name: transmembrane channel-like gene family 1
Synonyms: 4933416G09Rik, Bth, Beethoven
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 13409
VEGA: 19
Homologene: 23670
Bmp2k
Name: BMP2 inducible kinase
Synonyms: 4933417M22Rik, BIKE
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 140780
Homologene: 34134
Aldh1a3
Name: aldehyde dehydrogenase family 1, subfamily A3
Synonyms: ALDH6, RALDH3, retinaldehyde dehydrogenase 3, V1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 56847
HGNC: HGNC:409
Homologene: 68080
Itih4
Name: inter alpha-trypsin inhibitor, heavy chain 4
Synonyms: Itih-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 16427
HGNC: HGNC:6169
Homologene: 1670
Olfr1287
Name: olfactory receptor 1287
Synonyms: GA_x6K02T2Q125-72500603-72501520, MOR248-15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 257935
HGNC: null
Homologene: null
Gpbar1
Name: G protein-coupled bile acid receptor 1
Synonyms: GPR131, TGR5, BG37, M-BAR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 227289
Homologene: 18125
Rps6ka4
Name: ribosomal protein S6 kinase, polypeptide 4
Synonyms: 90kDa, 1110069D02Rik, MSK2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 56613
VEGA: 19
Homologene: 69288
Cyp3a41a
Name: cytochrome P450, family 3, subfamily a, polypeptide 41A
Synonyms: Cyp3a41, steroid inducible
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 53973
HGNC: HGNC:2638
Homologene: 133568
Olfr775
Name: olfactory receptor 775
Synonyms: GA_x6K02T2PULF-10936819-10937757, MOR111-7, MOR111-6, Olfr1518, MOR111-7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 258538
HGNC: null
Homologene: 115559
Zscan4d
Name: zinc finger and SCAN domain containing 4D
Synonyms: EG545913
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 545913
HGNC: null
Homologene: 85986
Pus7l
Name: pseudouridylate synthase 7-like
Synonyms: 3000003F02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 78895
Homologene: 12842
Krt27
Name: keratin 27
Synonyms: stpm, mIRSa3.1, Krt1-c29
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 16675
Homologene: 7805
Nhlrc1
Name: NHL repeat containing 1
Synonyms: B230309E09Rik, Malin, EPM2B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 105193
VEGA: 13
Homologene: 18439
Ptprv
Name: protein tyrosine phosphatase, receptor type, V
Synonyms: OST-PTP, Esp, mOST-PTP, OST
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 13924
Homologene: 7306
Runx3
Name: runt related transcription factor 3
Synonyms: Cbfa3, AML2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 12399
Homologene: 37914
Sun3
Name: Sad1 and UNC84 domain containing 3
Synonyms: D630047F21Rik, Sunc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 194974
Homologene: 51273
Atp6v1g2
Name: ATPase, H+ transporting, lysosomal V1 subunit G2
Synonyms: VAG2, lysosomal 13kDa, 1500002D01Rik, Atp6g2, NG38
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 66237
HGNC: HGNC:862
Homologene: 41518
Gm867
Name: predicted gene 867
Synonyms: LOC333670, LOC327769
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 333670
Homologene: 122921
Fkbp14
Name: FK506 binding protein 14
Synonyms: FKBP22
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 231997
Homologene: 23059
Olfr1222
Name: olfactory receptor 1222
Synonyms: GA_x6K02T2Q125-50604368-50603433, MOR233-14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258177
HGNC: null
Homologene: 73988
Gm7135
Name: predicted gene 7135
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 634346
HGNC: null
Homologene: 86643
Gm4845
Name: predicted gene 4845
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 226472
HGNC: null
Homologene: null
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • TACCAC to TAC, chromosome 1 at 74,279,545 bp
  • A to T, chromosome 1 at 97,354,076 bp
  • A to G, chromosome 1 at 135,118,848 bp
  • T to A, chromosome 1 at 141,256,885 bp
  • T to C, chromosome 1 at 183,331,115 bp
  • A to G, chromosome 2 at 29,164,550 bp
  • C to T, chromosome 2 at 29,733,655 bp
  • A to G, chromosome 2 at 31,393,025 bp
  • A to T, chromosome 2 at 68,220,992 bp
  • T to C, chromosome 2 at 88,034,661 bp
  • T to C, chromosome 2 at 89,125,338 bp
  • T to A, chromosome 2 at 103,976,143 bp
  • T to C, chromosome 2 at 111,449,683 bp
  • T to C, chromosome 2 at 156,017,718 bp
  • A to G, chromosome 2 at 158,435,508 bp
  • C to A, chromosome 3 at 37,232,504 bp
  • A to C, chromosome 3 at 59,932,740 bp
  • A to G, chromosome 3 at 133,486,759 bp
  • C to T, chromosome 4 at 41,120,167 bp
  • T to C, chromosome 4 at 117,681,036 bp
  • A to G, chromosome 4 at 135,171,135 bp
  • A to G, chromosome 4 at 135,346,720 bp
  • C to T, chromosome 4 at 148,244,216 bp
  • A to G, chromosome 5 at 21,960,426 bp
  • A to T, chromosome 5 at 93,187,694 bp
  • A to G, chromosome 5 at 97,087,085 bp
  • G to T, chromosome 5 at 112,335,747 bp
  • T to A, chromosome 5 at 134,395,627 bp
  • A to G, chromosome 5 at 145,720,048 bp
  • C to A, chromosome 6 at 18,406,526 bp
  • A to G, chromosome 6 at 54,592,958 bp
  • T to C, chromosome 6 at 141,980,873 bp
  • A to T, chromosome 7 at 11,165,347 bp
  • T to G, chromosome 7 at 39,537,080 bp
  • C to T, chromosome 7 at 43,658,972 bp
  • T to C, chromosome 7 at 46,150,867 bp
  • T to C, chromosome 7 at 46,287,991 bp
  • C to T, chromosome 7 at 66,419,179 bp
  • A to T, chromosome 7 at 104,179,529 bp
  • A to T, chromosome 7 at 117,667,342 bp
  • T to G, chromosome 8 at 88,707,232 bp
  • A to T, chromosome 9 at 66,104,905 bp
  • G to T, chromosome 9 at 106,212,340 bp
  • T to A, chromosome 9 at 113,903,916 bp
  • A to G, chromosome 10 at 75,939,802 bp
  • A to G, chromosome 10 at 79,903,005 bp
  • T to C, chromosome 10 at 129,251,272 bp
  • G to A, chromosome 11 at 9,038,311 bp
  • A to G, chromosome 11 at 79,619,671 bp
  • T to C, chromosome 11 at 88,394,655 bp
  • G to A, chromosome 11 at 99,346,896 bp
  • A to T, chromosome 11 at 104,335,564 bp
  • A to G, chromosome 12 at 51,762,497 bp
  • A to G, chromosome 12 at 101,983,493 bp
  • A to G, chromosome 13 at 47,013,740 bp
  • C to T, chromosome 13 at 53,131,918 bp
  • A to G, chromosome 14 at 8,518,736 bp
  • T to A, chromosome 14 at 30,892,287 bp
  • T to C, chromosome 14 at 54,971,671 bp
  • A to C, chromosome 15 at 36,054,876 bp
  • T to A, chromosome 15 at 44,677,667 bp
  • A to G, chromosome 15 at 94,529,488 bp
  • T to A, chromosome 16 at 21,466,469 bp
  • T to C, chromosome 17 at 25,724,566 bp
  • T to C, chromosome 17 at 30,656,985 bp
  • A to G, chromosome 17 at 35,237,172 bp
  • T to C, chromosome 17 at 35,555,429 bp
  • C to A, chromosome 17 at 67,738,834 bp
  • C to A, chromosome 17 at 80,525,335 bp
  • A to G, chromosome 18 at 5,054,025 bp
  • T to G, chromosome 18 at 54,889,890 bp
  • T to A, chromosome 18 at 89,064,085 bp
  • A to T, chromosome 19 at 6,840,310 bp
  • A to C, chromosome 19 at 20,906,955 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4975 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
042570-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.