Strain Name:
C57BL/6J-MtgxR4997Btlr/Mmmh
Stock Number:
042591-MU
Citation ID:
RRID:MMRRC_042591-MU
Other Names:
R4997 (G1), C57BL/6J-MtgxR4997Btlr
Major Collection:

Gene Information

Prss12
Name: protease, serine 12 neurotrypsin (motopsin)
Synonyms: motopsin, Bssp-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 19142
HGNC: HGNC:9477
Homologene: 7490
Foxm1
Name: forkhead box M1
Synonyms: Mpm2, Fkh16, WIN, HFH-11B, Trident, Foxm1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 14235
HGNC: HGNC:3818
Homologene: 7318
Pik3cd
Name: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
Synonyms: 2410099E07Rik, 2610208K16Rik, p110delta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 18707
HGNC: HGNC:8977
Homologene: 3686
Inpp5a
Name: inositol polyphosphate-5-phosphatase A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 212111
HGNC: HGNC:6076
Homologene: 4045
Ulk2
Name: unc-51 like kinase 2
Synonyms: Unc51.2, A830085I22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 29869
Homologene: 5891
Zmynd8
Name: zinc finger, MYND-type containing 8
Synonyms: 3632413B07Rik, RACK7, Prkcbp1, ZMYND8, 1110013E22Rik, 2010005I16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228880
HGNC: HGNC:9397
Homologene: 32679
Prrc2b
Name: proline-rich coiled-coil 2B
Synonyms: Bat2l, 5830434P21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227723
Homologene: 106649
Rad54l2
Name: RAD54 like 2 (S. cerevisiae)
Synonyms: Arip4, G630026H09Rik, Srisnf2l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 81000
Homologene: 56698
Qtrt1
Name: queuine tRNA-ribosyltransferase catalytic subunit 1
Synonyms: tRNA-guanine transglycosylase, 2610028E17Rik, Tgt
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 60507
VEGA: 9
Homologene: 11061
Zfp553
Name: zinc finger protein 553
Synonyms: C330013F15Rik, ENSMUSG00000054461, 2600009K23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233887
Homologene: 27098
Adgrg1
Name: adhesion G protein-coupled receptor G1
Synonyms: Cyt28, Gpr56
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 14766
HGNC: HGNC:4512
Homologene: 4156
Prkci
Name: protein kinase C, iota
Synonyms: Pkcl, 2310021H13Rik, PKClambda, Prkcl, aPKClambda, Pkci
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 18759
HGNC: HGNC:9404
Homologene: 37667
Wasf1
Name: WAS protein family, member 1
Synonyms: Scar, WAVE, WAVE-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 83767
Homologene: 2920
Xpnpep3
Name: X-prolyl aminopeptidase 3, mitochondrial
Synonyms: E430012M05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 321003
Scn8a
Name: sodium channel, voltage-gated, type VIII, alpha
Synonyms: ataxia 3, nmf58, mnd-2, motor end-plate disease, NMF335, nmf335, mnd2, med, nmf2, seal, NaCh6, Nav1.6, nur14, C630029C19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 20273
Homologene: 7927
Ttc3
Name: tetratricopeptide repeat domain 3
Synonyms: D16Ium21e, 2610202A04Rik, TPRD, D16Ium21
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 22129
Homologene: 2487
Supt5
Name: suppressor of Ty 5, DSIF elongation factor subunit
Synonyms: Supt5h, Spt5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 20924
Homologene: 2384
Abcc4
Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 4
Synonyms: MOAT-B, D630049P08Rik, MRP4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 239273
VEGA: 14
HGNC: HGNC:55
Homologene: 74563
Ppp1r10
Name: protein phosphatase 1, regulatory subunit 10
Synonyms: D17Ertd808e, 2610025H06Rik, PNUTS
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 52040
HGNC: HGNC:9284
Homologene: 2033
Ncor2
Name: nuclear receptor co-repressor 2
Synonyms: SMRTe, SMRT
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 20602
HGNC: HGNC:7673
Homologene: 31370
Brca1
Name: breast cancer 1, early onset
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 12189
HGNC: HGNC:1100
Homologene: 5276
Nubp1
Name: nucleotide binding protein 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 26425
HGNC: HGNC:8041
Homologene: 1857
Plekhg5
Name: pleckstrin homology domain containing, family G (with RhoGef domain) member 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 269608
Homologene: 10768
Ryr2
Name: ryanodine receptor 2, cardiac
Synonyms: 9330127I20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 20191
VEGA: 13
Homologene: 37423
Coch
Name: cochlin
Synonyms: D12H14S564E, Coch-5B2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 12810
VEGA: 12
HGNC: HGNC:2180
Homologene: 20868
Adcy1
Name: adenylate cyclase 1
Synonyms: D11Bwg1392e, I-AC, AC1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 432530
HGNC: HGNC:232
Homologene: 41419
Rph3a
Name: rabphilin 3A
Synonyms: 2900002P20Rik, Doc2 family
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 19894
Homologene: 7921
Arhgap23
Name: Rho GTPase activating protein 23
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 58996
Homologene: 104145
Epgn
Name: epithelial mitogen
Synonyms: epigen, 2310069M11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 71920
Homologene: 19527
Fchsd1
Name: FCH and double SH3 domains 1
Synonyms: A030002D08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 319262
Homologene: 14127
Mpzl1
Name: myelin protein zero-like 1
Synonyms: 1110007A10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 68481
HGNC: HGNC:7226
Homologene: 2939
Olfml1
Name: olfactomedin-like 1
Synonyms: MVAL564, mONT2, ONT2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 244198
Homologene: 45688
Tpd52
Name: tumor protein D52
Synonyms: mD52
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 21985
Homologene: 38007
Tiprl
Name: TIP41, TOR signalling pathway regulator-like (S. cerevisiae)
Synonyms: 1810011K17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226591
Homologene: 7140
Cep152
Name: centrosomal protein 152
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 99100
Homologene: 37159
Trerf1
Name: transcriptional regulating factor 1
Synonyms: Trep-132, 9430096I18Rik, Trep132
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224829
Homologene: 14129
Dpy19l4
Name: dpy-19-like 4 (C. elegans)
Synonyms: LOC381510, Narg3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 381510
Homologene: 18773
Thsd1
Name: thrombospondin, type I, domain 1
Synonyms: Tmtsp, 4833423O18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 56229
Homologene: 10264
Tnfrsf19
Name: tumor necrosis factor receptor superfamily, member 19
Synonyms: TRADE, TAJ, Troy, TAJ-ALPHA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 29820
VEGA: 14
Homologene: 8481
Tnfrsf25
Name: tumor necrosis factor receptor superfamily, member 25
Synonyms: WSL-LR, Tnfrsf12, Wsl, DR3, TRAMP, LARD, WSL-1, DDR3, TR3, APO-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 85030
Homologene: 13202
Invs
Name: inversin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 16348
Homologene: 7786
Muc19
Name: mucin 19
Synonyms: sld, apomucin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239611
Syk
Name: spleen tyrosine kinase
Synonyms: Sykb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 20963
Homologene: 2390
Hmcn2
Name: hemicentin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 665700
Homologene: 90772
Ttn
Name: titin
Synonyms: D830007G01Rik, L56, 1100001C23Rik, mdm, D330041I19Rik, 2310057K23Rik, 2310074I15Rik, 2310036G12Rik, shru, connectin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22138
Homologene: 130650
Piezo2
Name: piezo-type mechanosensitive ion channel component 2
Synonyms: Fam38b, Fam38b2, Piezo2, 9430028L06Rik, 9030411M15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 667742
Homologene: 49695
Egfem1
Name: EGF-like and EMI domain containing 1
Synonyms: 6130401L20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 75740
Homologene: 135950
Spata31
Name: spermatogenesis associated 31
Synonyms: Fam75a, Spata31a, 4930458L03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 78124
Homologene: 84621
Nlrp1b
Name: NLR family, pyrin domain containing 1B
Synonyms: Nalp1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 637515
Homologene: 19080
Lama4
Name: laminin, alpha 4
Synonyms: laminin [a]4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 16775
HGNC: HGNC:6484
Homologene: 37604
Tmed4
Name: transmembrane p24 trafficking protein 4
Synonyms: 1110014L17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 103694
Homologene: 5308
Calcrl
Name: calcitonin receptor-like
Synonyms: CRLR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 54598
Homologene: 21179
Afap1l1
Name: actin filament associated protein 1-like 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 106877
Homologene: 18728
Antxr2
Name: anthrax toxin receptor 2
Synonyms: 2310046B19Rik, cI-35, CMG-2, CMG2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 71914
Homologene: 43236
Slc16a12
Name: solute carrier family 16 (monocarboxylic acid transporters), member 12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 240638
Homologene: 130007
Il1r2
Name: interleukin 1 receptor, type II
Synonyms: Il1r-2, CD121b, IL-1 receptor beta chain
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 16178
HGNC: HGNC:5994
Homologene: 7783
9530053A07Rik
Name: RIKEN cDNA 9530053A07 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 319482
Homologene: 130055
Per2
Name: period circadian clock 2
Synonyms: mPer2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 18627
HGNC: HGNC:8846
Homologene: 7885
Accs
Name: 1-aminocyclopropane-1-carboxylate synthase (non-functional)
Synonyms: 2610203E10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 329470
Homologene: 75335
Prkcg
Name: protein kinase C, gamma
Synonyms: Prkcc, PKCgamma, Pkcc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 18752
HGNC: HGNC:9402
Homologene: 20602
Trim30a
Name: tripartite motif-containing 30A
Synonyms: Trim30, Rpt-1, Rpt1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 20128
Homologene: 114426
Itgad
Name: integrin, alpha D
Synonyms: Cd11d
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 381924
HGNC: HGNC:6146
Homologene: 56919
Dis3l
Name: DIS3 like exosome 3'-5' exoribonuclease
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 213550
Homologene: 15797
Nsun7
Name: NOL1/NOP2/Sun domain family, member 7
Synonyms: 4921525L17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 70918
Homologene: 11653
Myo3b
Name: myosin IIIB
Synonyms: A430065P19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 329421
Homologene: 51393
Rufy4
Name: RUN and FYVE domain containing 4
Synonyms: F930048N03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 435626
Homologene: 52359
Adam6a
Name: a disintegrin and metallopeptidase domain 6A
Synonyms: Adam6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 238406
HGNC: HGNC:213
Homologene: 128362
Serping1
Name: serine (or cysteine) peptidase inhibitor, clade G, member 1
Synonyms: C1 inhibitor, C1INH, C1nh
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 12258
HGNC: HGNC:1228
Homologene: 44
Dnaic1
Name: dynein, axonemal, intermediate chain 1
Synonyms: b2b1526Clo, 1110066F04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 68922
HGNC: HGNC:2954
Homologene: 8122
Gsdmc
Name: gasdermin C
Synonyms: Gsdmc1, Mlze
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 83492
HGNC: HGNC:7151
Homologene: 69487
Il27ra
Name: interleukin 27 receptor, alpha
Synonyms: Tccr, IL-27R, WSX-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 50931
Homologene: 3562
Col5a1
Name: collagen, type V, alpha 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 12831
HGNC: HGNC:2209
Homologene: 55434
Osmr
Name: oncostatin M receptor
Synonyms: OSMRB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 18414
HGNC: HGNC:8507
Homologene: 2972
Olfr498
Name: olfactory receptor 498
Synonyms: GA_x6K02T2PBJ9-10795522-10796514, MOR204-36
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258304
Homologene: 133600
Spata13
Name: spermatogenesis associated 13
Synonyms: ESTM11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 219140
Homologene: 19482
Llgl1
Name: LLGL1 scribble cell polarity complex component
Synonyms: Lgl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 16897
HGNC: HGNC:6628
Homologene: 31220
Shank3
Name: SH3 and multiple ankyrin repeat domains 3
Synonyms: ProSAP2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 58234
Homologene: 75163
Klk14
Name: kallikrein related-peptidase 14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 317653
HGNC: HGNC:6362
Homologene: 69348
Endou
Name: endonuclease, polyU-specific
Synonyms: Tcl-30, Pp11r
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 19011
VEGA: 15
Homologene: 48394
Pik3c2b
Name: phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta
Synonyms: PI3K-C2beta, C330011J12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 240752
HGNC: HGNC:8972
Homologene: 20582
Aldh3a1
Name: aldehyde dehydrogenase family 3, subfamily A1
Synonyms: Ahd-4, Ahd4, Aldh, Aldh3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 11670
HGNC: HGNC:405
Homologene: 20175
Hs3st2
Name: heparan sulfate (glucosamine) 3-O-sulfotransferase 2
Synonyms: A830061E14Rik, 6430516N12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 195646
HGNC: HGNC:5195
Homologene: 21220
Abca7
Name: ATP-binding cassette, sub-family A (ABC1), member 7
Synonyms: Abc51
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 27403
HGNC: HGNC:37
Homologene: 22783
Wnt10b
Name: wingless-type MMTV integration site family, member 10B
Synonyms: Wnt12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 22410
VEGA: 15
Homologene: 20721
Fitm1
Name: fat storage-inducing transmembrane protein 1
Synonyms: Cg10671, Fit1, 1110028A07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 68680
Homologene: 41695
Rhov
Name: ras homolog family member V
Synonyms: A030005A06Rik, Arhv
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228543
Homologene: 26426
Ppl
Name: periplakin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 19041
VEGA: 16
HGNC: HGNC:9273
Homologene: 2026
Isg15
Name: ISG15 ubiquitin-like modifier
Synonyms: G1p2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100038882
VEGA: 4
HGNC: HGNC:4053
Homologene: 48326
Spem2
Name: SPEM family member 2
Synonyms: 4933402P03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 108803
Homologene: 52178
Zfp41
Name: zinc finger protein 41
Synonyms: CTfin92, Zfp-41
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 22701
Homologene: 65280
Mad2l1bp
Name: MAD2L1 binding protein
Synonyms: CMT2B, CMT2A, 0610009D16Rik, 2510031P20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 66591
VEGA: 17
Homologene: 11990
A630023A22Rik
Name: RIKEN cDNA A630023A22 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 105518
VEGA: 14
Lce1a2
Name: late cornified envelope 1A2
Synonyms: 1110004E04Rik, Sprrl2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 73722
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 40,121,046 bp
  • T to C, chromosome 1 at 74,147,663 bp
  • T to A, chromosome 1 at 91,450,783 bp
  • C to T, chromosome 1 at 133,105,081 bp
  • A to G, chromosome 1 at 165,220,190 bp
  • A to C, chromosome 1 at 165,601,781 bp
  • T to A, chromosome 2 at 28,032,782 bp
  • T to A, chromosome 2 at 31,401,708 bp
  • A to G, chromosome 2 at 32,222,311 bp
  • A to G, chromosome 2 at 70,258,083 bp
  • C to T, chromosome 2 at 76,884,059 bp
  • T to C, chromosome 2 at 76,946,271 bp
  • A to T, chromosome 2 at 84,351,248 bp
  • T to C, chromosome 2 at 84,770,285 bp
  • A to T, chromosome 2 at 93,841,883 bp
  • C to T, chromosome 2 at 119,270,468 bp
  • T to C, chromosome 2 at 125,586,351 bp
  • G to T, chromosome 2 at 165,792,816 bp
  • A to G, chromosome 3 at 8,934,996 bp
  • A to G, chromosome 3 at 29,153,590 bp
  • T to C, chromosome 3 at 31,031,226 bp
  • A to G, chromosome 3 at 92,669,088 bp
  • T to C, chromosome 3 at 123,447,208 bp
  • A to G, chromosome 4 at 11,287,493 bp
  • A to G, chromosome 4 at 41,597,919 bp
  • A to G, chromosome 4 at 48,396,332 bp
  • A to C, chromosome 4 at 149,658,984 bp
  • A to C, chromosome 4 at 152,107,996 bp
  • T to C, chromosome 4 at 152,117,696 bp
  • C to T, chromosome 4 at 156,199,697 bp
  • A to G, chromosome 5 at 66,295,839 bp
  • A to G, chromosome 5 at 91,032,239 bp
  • A to G, chromosome 5 at 97,977,694 bp
  • A to T, chromosome 5 at 120,963,843 bp
  • T to C, chromosome 5 at 125,034,010 bp
  • A to G, chromosome 6 at 128,365,768 bp
  • T to C, chromosome 7 at 3,322,581 bp
  • T to G, chromosome 7 at 28,143,924 bp
  • T to C, chromosome 7 at 28,316,037 bp
  • G to A, chromosome 7 at 43,692,077 bp
  • T to A, chromosome 7 at 104,411,620 bp
  • A to G, chromosome 7 at 107,571,206 bp
  • C to A, chromosome 7 at 108,465,494 bp
  • T to A, chromosome 7 at 121,500,456 bp
  • T to A, chromosome 7 at 127,235,511 bp
  • C to T, chromosome 7 at 128,174,067 bp
  • A to T, chromosome 7 at 139,400,738 bp
  • T to A, chromosome 8 at 22,243,324 bp
  • A to T, chromosome 8 at 84,039,527 bp
  • A to G, chromosome 8 at 95,009,520 bp
  • A to G, chromosome 9 at 21,417,358 bp
  • A to G, chromosome 9 at 64,311,942 bp
  • A to C, chromosome 9 at 106,722,909 bp
  • C to A, chromosome 10 at 39,092,266 bp
  • C to T, chromosome 10 at 40,934,604 bp
  • C to A, chromosome 10 at 80,007,320 bp
  • T to A, chromosome 11 at 6,274,500 bp
  • A to C, chromosome 11 at 7,161,298 bp
  • C to T, chromosome 11 at 60,709,568 bp
  • T to C, chromosome 11 at 61,212,311 bp
  • T to C, chromosome 11 at 61,799,156 bp
  • T to C, chromosome 11 at 69,817,732 bp
  • T to A, chromosome 11 at 71,218,334 bp
  • T to A, chromosome 11 at 97,452,020 bp
  • A to C, chromosome 11 at 101,524,333 bp
  • T to A, chromosome 12 at 51,603,181 bp
  • G to T, chromosome 12 at 113,545,371 bp
  • A to T, chromosome 13 at 11,595,306 bp
  • A to T, chromosome 13 at 52,612,448 bp
  • G to A, chromosome 13 at 64,919,723 bp
  • A to T, chromosome 14 at 34,053,666 bp
  • T to C, chromosome 14 at 55,576,907 bp
  • T to C, chromosome 14 at 60,709,459 bp
  • T to C, chromosome 14 at 60,971,209 bp
  • C to T, chromosome 14 at 118,516,503 bp
  • G to T, chromosome 15 at 6,815,639 bp
  • A to T, chromosome 15 at 63,776,780 bp
  • C to T, chromosome 15 at 75,618,768 bp
  • T to A, chromosome 15 at 81,448,376 bp
  • T to A, chromosome 15 at 89,549,698 bp
  • G to A, chromosome 15 at 91,927,774 bp
  • A to G, chromosome 15 at 97,719,577 bp
  • C to A, chromosome 15 at 98,774,203 bp
  • A to G, chromosome 15 at 100,957,054 bp
  • C to A, chromosome 16 at 5,089,371 bp
  • T to C, chromosome 16 at 10,421,321 bp
  • T to G, chromosome 16 at 94,452,982 bp
  • A to G, chromosome 17 at 35,924,084 bp
  • G to T, chromosome 17 at 46,152,878 bp
  • A to T, chromosome 17 at 47,315,040 bp
  • C to T, chromosome 18 at 37,959,873 bp
  • C to T, chromosome 18 at 61,751,808 bp
  • A to G, chromosome 18 at 63,083,113 bp
  • T to A, chromosome 19 at 34,674,958 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4997 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
042591-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.