Strain Name:
C57BL/6J-MtgxR5034Btlr/Mmmh
Stock Number:
042625-MU
Citation ID:
RRID:MMRRC_042625-MU
Other Names:
R5034 (G1), C57BL/6J-MtgxR5034Btlr
Major Collection:

Gene Information

Pcdh9
Name: protocadherin 9
Synonyms: C630029H24Rik, 1500001L12Rik, LOC382930, A730003J17Rik, C530050I23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 211712
HGNC: HGNC:8661
Homologene: 10698
Ifi203
Name: interferon activated gene 203
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 15950
HGNC: HGNC:5395
Homologene: 115929
Rilpl1
Name: Rab interacting lysosomal protein-like 1
Synonyms: 6330559I19Rik, 2900002H16Rik, GOSPEL
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 75695
Homologene: 15619
Rictor
Name: RPTOR independent companion of MTOR, complex 2
Synonyms: 6030405M08Rik, D530039E11Rik, 4921505C17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 78757
VEGA: 15
Homologene: 34317
Vps35l
Name: VPS35 endosomal protein sorting factor like
Synonyms: 9030624J02Rik, Vsp35l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 71517
Homologene: 10659
Usp48
Name: ubiquitin specific peptidase 48
Synonyms: D330022K21Rik, 2810449C13Rik, Usp31
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 170707
Homologene: 12988
Nf1
Name: neurofibromin 1
Synonyms: neurofibromin, Nf-1, Dsk9, Mhdadsk9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 18015
HGNC: HGNC:7765
Homologene: 226
Ttc3
Name: tetratricopeptide repeat domain 3
Synonyms: TPRD, D16Ium21, 2610202A04Rik, D16Ium21e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 22129
Homologene: 2487
Sfpq
Name: splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)
Synonyms: 9030402K04Rik, D4Ertd314e, 2810416M14Rik, 5730453G22Rik, 1110004P21Rik, REP1, PSF
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 71514
Homologene: 3714
Tcf3
Name: transcription factor 3
Synonyms: ALF2, E2A, E47, E12, Pan2, Pan1, A1, Tcfe2a, bHLHb21
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 21423
Homologene: 2408
Asxl2
Name: ASXL transcriptional regulator 2
Synonyms: 4930556B16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 75302
Homologene: 10102
Lin9
Name: lin-9 homolog (C. elegans)
Synonyms: 2700022J23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 72568
Homologene: 35252
Dctn4
Name: dynactin 4
Synonyms: p62, 4930547K17Rik, 1110001K06Rik, C130039E17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 67665
VEGA: 18
Homologene: 9430
Vps18
Name: VPS18 CORVET/HOPS core subunit
Synonyms: 9930024E13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228545
Homologene: 13302
Pphln1
Name: periphilin 1
Synonyms: 1600022A19Rik, 1110063K05Rik, CR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223828
VEGA: 15
Homologene: 9533
Acaca
Name: acetyl-Coenzyme A carboxylase alpha
Synonyms: acetyl-CoA carboxylase, Acc1, LOC327983, Acac, A530025K05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 107476
HGNC: HGNC:84
Homologene: 31015
Magel2
Name: MAGE family member L2
Synonyms: NDNL1, Mage-l2, nM15, ns7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 27385
HGNC: HGNC:6814
Homologene: 8460
Rmdn3
Name: regulator of microtubule dynamics 3
Synonyms: 1200015F23Rik, Fam82a2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 67809
Homologene: 34926
Hsd17b11
Name: hydroxysteroid (17-beta) dehydrogenase 11
Synonyms: Pan1b, retSDR2, Dhrs8, 17beta-HSD11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 114664
Homologene: 69209
Cops7a
Name: COP9 signalosome subunit 7A
Synonyms: COP9 complex S7a, D6Ertd35e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 26894
Homologene: 22685
Tgm3
Name: transglutaminase 3, E polypeptide
Synonyms: TG E, we
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 21818
Homologene: 20690
Foxd3
Name: forkhead box D3
Synonyms: Genesis, Hfh2, CWH3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 15221
HGNC: HGNC:3804
Homologene: 49239
Usf3
Name: upstream transcription factor family member 3
Synonyms: LOC207806, LOC385650, 5530400K22Rik, Gm608
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 207806
Homologene: 19504
Col12a1
Name: collagen, type XII, alpha 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12816
HGNC: HGNC:2188
Homologene: 3217
Rnf213
Name: ring finger protein 213
Synonyms: D11Ertd759e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 672511
Homologene: 45439
Pde5a
Name: phosphodiesterase 5A, cGMP-specific
Synonyms: PDE5A1, Pde5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 242202
HGNC: HGNC:8784
Homologene: 842
Zscan18
Name: zinc finger and SCAN domain containing 18
Synonyms: EG232875
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 232875
Homologene: 122136
Ulk3
Name: unc-51-like kinase 3
Synonyms: 1200015E14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 71742
VEGA: 9
Homologene: 68482
Obscn
Name: obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Synonyms: LOC380698, OTTMUSG00000005786
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 380698
Homologene: 70869
Myo7b
Name: myosin VIIB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 17922
HGNC: HGNC:7607
Homologene: 81947
Csmd3
Name: CUB and Sushi multiple domains 3
Synonyms: 4930500N14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239420
Homologene: 65982
Kif21a
Name: kinesin family member 21A
Synonyms: N-5 kinesin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 16564
VEGA: 15
Homologene: 56761
Dennd5a
Name: DENN/MADD domain containing 5A
Synonyms: ORF37, 1500012B19Rik, Rab6ip1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 19347
Homologene: 14584
Sspo
Name: SCO-spondin
Synonyms: C79529, Scospondin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 243369
Homologene: 45453
Csmd2
Name: CUB and Sushi multiple domains 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 329942
Homologene: 89034
Tmprss11f
Name: transmembrane protease, serine 11f
Synonyms: 4732406D01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 243083
Homologene: 65356
Trim50
Name: tripartite motif-containing 50
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 215061
Homologene: 14548
Olfr1026
Name: olfactory receptor 1026
Synonyms: GA_x6K02T2Q125-47402610-47403533, MOR196-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258577
Homologene: 73971
Sdcbp
Name: syndecan binding protein
Synonyms: syntenin, syndecan interacting protein, Sycl, MDA-9, syntenin-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 53378
Homologene: 4110
Pcdhb14
Name: protocadherin beta 14
Synonyms: Pcdhb17, PcdhbN, 2210006M07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93885
Homologene: 70876
Dmwd
Name: dystrophia myotonica-containing WD repeat motif
Synonyms: 59, DMR-N9, Dm9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 13401
HGNC: HGNC:2936
Homologene: 22559
Adam6b
Name: a disintegrin and metallopeptidase domain 6B
Synonyms: 4930523C11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 238405
Homologene: 128362
Ahsg
Name: alpha-2-HS-glycoprotein
Synonyms: fetuin-A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 11625
VEGA: 16
HGNC: HGNC:349
Homologene: 1225
Galk2
Name: galactokinase 2
Synonyms: Gk2, 2810017M24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 69976
HGNC: HGNC:4119
Homologene: 13654
Far2
Name: fatty acyl CoA reductase 2
Synonyms: Mlstd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 330450
Homologene: 69247
Mrgpra4
Name: MAS-related GPR, member A4
Synonyms: MrgA4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 235854
Homologene: 131159
Dsc1
Name: desmocollin 1
Synonyms: Dsc1b, Dsc1a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 13505
VEGA: 18
HGNC: HGNC:3035
Homologene: 22761
Ubash3b
Name: ubiquitin associated and SH3 domain containing, B
Synonyms: 2810457I06Rik, TULA-2, Sts-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 72828
Homologene: 13152
Zfp354c
Name: zinc finger protein 354C
Synonyms: Kid3, AJ18, 5330421P20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 30944
Homologene: 56606
Sra1
Name: steroid receptor RNA activator 1
Synonyms: Srap
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 24068
Homologene: 11906
Septin8
Name: septin 8
Synonyms: Sepl, Sept8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20362
Homologene: 57205
Slc35b3
Name: solute carrier family 35, member B3
Synonyms: 4921526O06Rik, PAPST2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 108652
VEGA: 13
Homologene: 9313
Oosp2
Name: oocyte secreted protein 2
Synonyms: LOC225922, Tmem122, Plac1l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 225922
Homologene: 52157
Pde2a
Name: phosphodiesterase 2A, cGMP-stimulated
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 207728
HGNC: HGNC:8777
Homologene: 1952
Trdv2-2
Name: T cell receptor delta variable 2-2
Synonyms: Gm17015
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 320913
Hcar1
Name: hydrocarboxylic acid receptor 1
Synonyms: Gpr81
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 243270
HGNC: HGNC:4532
Homologene: 13060
Scyl1
Name: SCY1-like 1 (S. cerevisiae)
Synonyms: p105, mfd, 2810011O19Rik, Ntkl, mdf
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 78891
VEGA: 19
Homologene: 6947
Gm15583
Name: predicted gene 15583
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Homologene: 138455
5830405F06Rik
Name: RIKEN cDNA 5830405F06 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Kdm6bos
Name: KDM1 lysine (K)-specific demethylase 6B, opposite strand
Synonyms: 1700064E03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Ighv9-2
Name: immunoglobulin heavy variable V9-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 629818
Ighv1-77
Name: immunoglobulin heavy variable 1-77
Synonyms: Gm16746
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 619994
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to T, chromosome 1 at 146,727,720 bp
  • T to C, chromosome 1 at 173,922,569 bp
  • T to A, chromosome 1 at 180,669,198 bp
  • C to A, chromosome 2 at 85,923,547 bp
  • G to T, chromosome 2 at 119,147,577 bp
  • A to T, chromosome 2 at 119,293,306 bp
  • A to T, chromosome 2 at 125,929,575 bp
  • T to C, chromosome 2 at 130,037,484 bp
  • G to C, chromosome 3 at 122,852,586 bp
  • G to T, chromosome 3 at 122,852,587 bp
  • G to A, chromosome 4 at 6,393,118 bp
  • G to A, chromosome 4 at 99,657,090 bp
  • A to G, chromosome 4 at 127,023,669 bp
  • G to A, chromosome 4 at 128,059,108 bp
  • C to T, chromosome 4 at 137,606,757 bp
  • C to T, chromosome 5 at 86,591,384 bp
  • C to T, chromosome 5 at 104,018,221 bp
  • T to C, chromosome 5 at 123,879,669 bp
  • T to C, chromosome 5 at 124,493,824 bp
  • T to C, chromosome 5 at 135,367,293 bp
  • A to G, chromosome 6 at 41,059,690 bp
  • A to T, chromosome 6 at 48,480,823 bp
  • A to G, chromosome 6 at 124,962,620 bp
  • C to A, chromosome 6 at 148,173,441 bp
  • A to G, chromosome 7 at 12,774,145 bp
  • T to C, chromosome 7 at 19,080,294 bp
  • A to G, chromosome 7 at 47,981,569 bp
  • A to T, chromosome 7 at 62,379,868 bp
  • A to G, chromosome 7 at 101,502,024 bp
  • A to T, chromosome 7 at 109,899,797 bp
  • T to C, chromosome 7 at 118,791,388 bp
  • T to C, chromosome 9 at 41,029,740 bp
  • T to A, chromosome 9 at 57,593,764 bp
  • T to C, chromosome 9 at 79,657,367 bp
  • A to G, chromosome 10 at 80,417,543 bp
  • T to C, chromosome 11 at 50,815,039 bp
  • A to G, chromosome 11 at 53,534,438 bp
  • T to A, chromosome 11 at 59,061,676 bp
  • A to G, chromosome 11 at 69,401,910 bp
  • C to T, chromosome 11 at 79,444,150 bp
  • T to A, chromosome 11 at 84,245,264 bp
  • G to A, chromosome 11 at 119,410,807 bp
  • A to G, chromosome 12 at 3,502,193 bp
  • G to T, chromosome 12 at 113,490,927 bp
  • A to G, chromosome 12 at 114,109,405 bp
  • C to T, chromosome 12 at 115,861,874 bp
  • A to G, chromosome 13 at 38,943,158 bp
  • C to A, chromosome 14 at 53,961,425 bp
  • T to A, chromosome 14 at 93,326,849 bp
  • T to C, chromosome 15 at 6,768,095 bp
  • T to C, chromosome 15 at 47,629,287 bp
  • T to A, chromosome 15 at 90,968,358 bp
  • T to C, chromosome 15 at 93,452,129 bp
  • C to A, chromosome 16 at 22,898,900 bp
  • A to C, chromosome 16 at 44,216,399 bp
  • A to G, chromosome 16 at 94,459,791 bp
  • T to A, chromosome 18 at 20,095,027 bp
  • A to G, chromosome 18 at 31,971,387 bp
  • A to G, chromosome 18 at 36,678,995 bp
  • T to C, chromosome 18 at 37,448,806 bp
  • A to G, chromosome 18 at 60,552,884 bp
  • T to A, chromosome 19 at 5,759,994 bp
  • T to C, chromosome 19 at 11,651,535 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5034 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
042625-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.