Strain Name:
C57BL/6J-MtgxR5079Btlr/Mmmh
Stock Number:
042668-MU
Citation ID:
RRID:MMRRC_042668-MU
Other Names:
R5079 (G1), C57BL/6J-MtgxR5079Btlr
Major Collection:

Gene Information

Ncor1
Name: nuclear receptor co-repressor 1
Synonyms: A230020K14Rik, N-CoR, 5730405M06Rik, Rxrip13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20185
HGNC: HGNC:7672
Homologene: 38166
Lyst
Name: lysosomal trafficking regulator
Synonyms: D13Sfk13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 17101
VEGA: 13
HGNC: HGNC:1968
Homologene: 61
Kat2b
Name: K(lysine) acetyltransferase 2B
Synonyms: Pcaf, A930006P13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 18519
HGNC: HGNC:8638
Homologene: 20834
Ggta1
Name: glycoprotein galactosyltransferase alpha 1, 3
Synonyms: glycoprotein alpha galactosyl transferase 1, alpha3GalT, Ggta-1, Gal, GALT, alpha Gal, Ggta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14594
HGNC: HGNC:4253
Homologene: 7730
Zfp638
Name: zinc finger protein 638
Synonyms: Zfml, Np220
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 18139
Homologene: 7447
Stam
Name: signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
Synonyms: STAM1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20844
Homologene: 37788
Dop1a
Name: DOP1 leucine zipper like protein A
Synonyms: Dopey1, B130005I07Rik, D9Ertd809e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 320615
Homologene: 26645
Wapl
Name: WAPL cohesin release factor
Synonyms: Wapal, A530089A20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 218914
Homologene: 41002
Tmem87a
Name: transmembrane protein 87A
Synonyms: A930025J12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 211499
Homologene: 9165
N4bp2
Name: NEDD4 binding protein 2
Synonyms: LOC333789, B3bp, LOC386488
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 333789
Homologene: 32396
Pot1b
Name: protection of telomeres 1B
Synonyms: 2810458H16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 72836
VEGA: 17
Homologene: 87058
Rcn1
Name: reticulocalbin 1
Synonyms: Rcn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 19672
HGNC: HGNC:9934
Homologene: 20637
Rnd2
Name: Rho family GTPase 2
Synonyms: Rohn, Arhn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 11858
Homologene: 21123
Casc3
Name: cancer susceptibility candidate 3
Synonyms: Mln51, Btz
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 192160
Homologene: 7208
Ror1
Name: receptor tyrosine kinase-like orphan receptor 1
Synonyms: 2810404D04Rik, Ntrkr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 26563
Homologene: 3675
4930522L14Rik
Name: RIKEN cDNA 4930522L14 gene
Synonyms: Gm42152
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100041734
Glb1l2
Name: galactosidase, beta 1-like 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 244757
Homologene: 71790
Lrrc4
Name: leucine rich repeat containing 4
Synonyms: NGL2, NGL-2, Nag14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 192198
Homologene: 36403
Oser1
Name: oxidative stress responsive serine rich 1
Synonyms: 3230401D17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 66680
Homologene: 9521
Paxbp1
Name: PAX3 and PAX7 binding protein 1
Synonyms: 1810007M14Rik, Gcfc1, Pax3/7bp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 67367
Homologene: 9604
Tnks1bp1
Name: tankyrase 1 binding protein 1
Synonyms: TAB182
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228140
Homologene: 14117
Itpr3
Name: inositol 1,4,5-triphosphate receptor 3
Synonyms: Itpr-3, Ip3r3, tf
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 16440
HGNC: HGNC:6182
Homologene: 1675
Nbas
Name: neuroblastoma amplified sequence
Synonyms: 4933425L03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 71169
VEGA: 12
Homologene: 41073
Fat3
Name: FAT atypical cadherin 3
Synonyms: 9430076A06Rik, D430038H04Rik, LOC382129, LOC234973
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 270120
VEGA: 9
Homologene: 82252
Man2c1
Name: mannosidase, alpha, class 2C, member 1
Synonyms: 1110025H24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 73744
HGNC: HGNC:6827
Homologene: 4887
Gm6614
Name: predicted gene 6614
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 625716
Homologene: 87075
Gucy2d
Name: guanylate cyclase 2d
Synonyms: guanylyl cyclase D
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 14918
Homologene: 71540
Sycp1
Name: synaptonemal complex protein 1
Synonyms: SCP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 20957
Homologene: 2389
Ormdl1
Name: ORM1-like 1 (S. cerevisiae)
Synonyms: C730042F17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227102
Homologene: 41135
Trpm5
Name: transient receptor potential cation channel, subfamily M, member 5
Synonyms: 9430099A16Rik, Mtr1, Ltrpc5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 56843
Homologene: 22818
Abca9
Name: ATP-binding cassette, sub-family A (ABC1), member 9
Synonyms: D630040K07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217262
HGNC: HGNC:39
Homologene: 33332
Tas2r123
Name: taste receptor, type 2, member 123
Synonyms: T2R23, mGR23, STC 9-2, mt2r55, Tas2r23
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 353167
Homologene: 45450
Pcnx
Name: pecanex homolog
Synonyms: 3526401J03Rik, 2900024E21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 54604
VEGA: 12
Homologene: 40997
Crybg2
Name: crystallin beta-gamma domain containing 2
Synonyms: Aim1l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230806
Homologene: 19232
Slc9a3
Name: solute carrier family 9 (sodium/hydrogen exchanger), member 3
Synonyms: NHE3, 9030624O13Rik, NHE-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 105243
VEGA: 13
Homologene: 55804
Mapkbp1
Name: mitogen-activated protein kinase binding protein 1
Synonyms: 2810483F24Rik, Jnkbp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 26390
Homologene: 69109
Klra17
Name: killer cell lectin-like receptor, subfamily A, member 17
Synonyms: Ly49q1, Ly-49Q, Ly49Q
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 170733
Olfr1136
Name: olfactory receptor 1136
Synonyms: MOR177-3, GA_x6K02T2Q125-49193051-49192119
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258653
Homologene: 74193
Vmn1r87
Name: vomeronasal 1 receptor 87
Synonyms: V1rk1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 171261
Homologene: 134023
Styk1
Name: serine/threonine/tyrosine kinase 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 243659
Homologene: 49545
Sorcs2
Name: sortilin-related VPS10 domain containing receptor 2
Synonyms: VPS10 domain receptor protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 81840
Homologene: 56899
Agbl4
Name: ATP/GTP binding protein-like 4
Synonyms: 4930578N11Rik, 4931433A01Rik, Ccp6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 78933
Homologene: 84880
Ankrd16
Name: ankyrin repeat domain 16
Synonyms: 2810455F06Rik, D430029B21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 320816
Homologene: 19509
Traf3ip2
Name: TRAF3 interacting protein 2
Synonyms: Act1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 103213
HGNC: HGNC:1343
Homologene: 15885
Etfdh
Name: electron transferring flavoprotein, dehydrogenase
Synonyms: 0610010I20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 66841
HGNC: HGNC:3483
Homologene: 3275
Gba2
Name: glucosidase beta 2
Synonyms: bile acid
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230101
Homologene: 10859
Catsperd
Name: cation channel sperm associated auxiliary subunit delta
Synonyms: Tmem146, 4921529N20Rik, Gm6095, 4933402B14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 106757
VEGA: 17
Homologene: 51896
Pogk
Name: pogo transposable element with KRAB domain
Synonyms: 9130401E23Rik, BASS2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 71592
Homologene: 32346
Dipk1c
Name: divergent protein kinase domain 1C
Synonyms: B230399E16Rik, Fam69c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 240479
Homologene: 45477
Vezt
Name: vezatin, adherens junctions transmembrane protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 215008
Homologene: 9739
Usp49
Name: ubiquitin specific peptidase 49
Synonyms: C330046L10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224836
Homologene: 10235
Csn3
Name: casein kappa
Synonyms: Csnk, CSN10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 12994
HGNC: HGNC:2446
Homologene: 3818
Slc6a20b
Name: solute carrier family 6 (neurotransmitter transporter), member 20B
Synonyms: Slc6a20, XT3, Xtrp3, Sit1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 22599
Homologene: 130652
Crisp1
Name: cysteine-rich secretory protein 1
Synonyms: CRISP-1, Aeg1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 11571
Homologene: 135665
Bpifc
Name: BPI fold containing family C
Synonyms: Bpil2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 270757
Homologene: 18383
Sall2
Name: spalt like transcription factor 2
Synonyms: Msal-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 50524
Homologene: 9269
Vmn2r39
Name: vomeronasal 2, receptor 39
Synonyms: EG545909
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 545909
Homologene: 113703
Gm5591
Name: predicted gene 5591
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 434171
Homologene: 80005
Gm5084
Name: predicted gene 5084
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 100503759
VEGA: 13
Sh2d6
Name: SH2 domain containing 6
Synonyms: 4933424C13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 71130
Homologene: 65986
Rcvrn
Name: recoverin
Synonyms: guanylate cyclase activator, cancer associated retinopathy protein, S-modulin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 19674
HGNC: HGNC:9937
Homologene: 2177
Gm15677
Name: predicted gene 15677
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Nme9
Name: NME/NM23 family member 9
Synonyms: Txndc6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 623534
Homologene: 52255
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 53,308,934 bp
  • A to G, chromosome 1 at 166,399,164 bp
  • A to G, chromosome 2 at 11,778,899 bp
  • T to C, chromosome 2 at 14,074,539 bp
  • A to G, chromosome 2 at 35,422,237 bp
  • C to A, chromosome 2 at 85,062,626 bp
  • C to A, chromosome 2 at 87,693,208 bp
  • A to G, chromosome 2 at 105,399,057 bp
  • A to G, chromosome 2 at 120,013,733 bp
  • A to T, chromosome 2 at 120,375,482 bp
  • G to A, chromosome 2 at 163,406,936 bp
  • T to C, chromosome 3 at 79,618,398 bp
  • A to G, chromosome 3 at 102,878,800 bp
  • G to T, chromosome 4 at 43,568,640 bp
  • T to A, chromosome 4 at 100,441,422 bp
  • T to A, chromosome 4 at 111,566,629 bp
  • T to C, chromosome 4 at 134,074,253 bp
  • T to G, chromosome 5 at 36,043,452 bp
  • G to A, chromosome 5 at 65,811,977 bp
  • T to C, chromosome 5 at 87,929,767 bp
  • T to C, chromosome 5 at 109,737,330 bp
  • T to A, chromosome 6 at 28,830,770 bp
  • G to A, chromosome 6 at 72,519,850 bp
  • A to G, chromosome 6 at 83,929,456 bp
  • C to A, chromosome 6 at 129,872,196 bp
  • G to A, chromosome 6 at 131,301,713 bp
  • A to G, chromosome 6 at 132,847,718 bp
  • A to C, chromosome 6 at 141,972,347 bp
  • A to G, chromosome 7 at 9,023,490 bp
  • C to A, chromosome 7 at 13,132,326 bp
  • G to T, chromosome 7 at 38,522,136 bp
  • A to T, chromosome 7 at 98,458,268 bp
  • C to T, chromosome 7 at 132,154,285 bp
  • G to T, chromosome 7 at 143,074,015 bp
  • T to C, chromosome 9 at 15,999,127 bp
  • T to C, chromosome 9 at 26,771,109 bp
  • A to G, chromosome 9 at 57,136,716 bp
  • T to A, chromosome 9 at 86,487,421 bp
  • A to G, chromosome 9 at 99,459,702 bp
  • T to A, chromosome 9 at 123,598,498 bp
  • T to C, chromosome 10 at 39,626,477 bp
  • T to C, chromosome 10 at 85,981,304 bp
  • T to C, chromosome 10 at 94,020,624 bp
  • T to A, chromosome 11 at 62,345,237 bp
  • T to A, chromosome 11 at 67,702,941 bp
  • C to T, chromosome 11 at 98,810,426 bp
  • C to T, chromosome 11 at 101,468,999 bp
  • A to T, chromosome 11 at 110,145,569 bp
  • A to T, chromosome 12 at 13,374,711 bp
  • C to A, chromosome 12 at 81,979,089 bp
  • T to C, chromosome 13 at 13,757,353 bp
  • T to A, chromosome 13 at 60,212,825 bp
  • A to T, chromosome 13 at 74,164,287 bp
  • G to A, chromosome 14 at 34,724,757 bp
  • G to T, chromosome 14 at 52,314,754 bp
  • C to A, chromosome 16 at 91,025,146 bp
  • T to C, chromosome 17 at 27,098,423 bp
  • A to T, chromosome 17 at 40,308,976 bp
  • A to G, chromosome 17 at 47,673,221 bp
  • T to A, chromosome 17 at 53,663,638 bp
  • A to T, chromosome 17 at 55,669,801 bp
  • T to C, chromosome 17 at 56,658,153 bp
  • A to T, chromosome 18 at 84,730,577 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5079 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
042668-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.