Strain Name:
C57BL/6J-MtgxR5158Btlr/Mmmh
Stock Number:
042740-MU
Citation ID:
RRID:MMRRC_042740-MU
Other Names:
R5158 (G1), C57BL/6J-MtgxR5158Btlr
Major Collection:

Gene Information

Kif3a
Name: kinesin family member 3A
Synonyms: Kifl, Kns3, kinesin-II subunit, N-4 kinesin, Kif3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 16568
HGNC: HGNC:6319
Homologene: 38266
Ngf
Name: nerve growth factor
Synonyms: Ngfb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 18049
HGNC: HGNC:7808
Homologene: 1876
Ptdss2
Name: phosphatidylserine synthase 2
Synonyms: PSS2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 27388
Homologene: 8462
Iqgap1
Name: IQ motif containing GTPase activating protein 1
Synonyms: D7Ertd237e, D7Ertd257e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 29875
HGNC: HGNC:6110
Homologene: 74514
Sptan1
Name: spectrin alpha, non-erythrocytic 1
Synonyms: alphaII-spectrin, 2610027H02Rik, Spna-2, alpha-fodrin, Spna2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20740
Homologene: 2353
Ctdspl2
Name: CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
Synonyms: D2Ertd485e, SCP4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 329506
Homologene: 32311
Psmb2
Name: proteasome (prosome, macropain) subunit, beta type 2
Synonyms: D4Wsu33e, HC7-I
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 26445
HGNC: HGNC:9539
Homologene: 2088
Kat6b
Name: K(lysine) acetyltransferase 6B
Synonyms: B130044K16Rik, qkf, querkopf, monocytic leukemia, Myst4, Morf
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 54169
Homologene: 136480
Cobl
Name: cordon-bleu WH2 repeat
Synonyms: C530045F18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 12808
Homologene: 9058
Ndc1
Name: NDC1 transmembrane nucleoporin
Synonyms: sks, 2810475A17Rik, Tmem48
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 72787
Homologene: 41224
N4bp2
Name: NEDD4 binding protein 2
Synonyms: B3bp, LOC386488, LOC333789
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 333789
Homologene: 32396
L3mbtl3
Name: L3MBTL3 histone methyl-lysine binding protein
Synonyms: MBT-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 237339
Homologene: 18226
Ehmt2
Name: euchromatic histone lysine N-methyltransferase 2
Synonyms: Bat8, KMT1C, G9a, D17Ertd710e, NG36
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 110147
Homologene: 48460
Ptprc
Name: protein tyrosine phosphatase, receptor type, C
Synonyms: CD45, Lyt-4, Ly-5, T200, B220
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 19264
HGNC: HGNC:9666
Homologene: 2126
Mcf2l
Name: mcf.2 transforming sequence-like
Synonyms: C130040G20Rik, Dbs
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 17207
Homologene: 11804
Adnp2
Name: ADNP homeobox 2
Synonyms: 8430420L05Rik, Zfp508
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 240442
Homologene: 8945
Il1f9
Name: interleukin 1 family, member 9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 215257
Homologene: 49595
Nup88
Name: nucleoporin 88
Synonyms: Prei2, Nup84
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 19069
HGNC: HGNC:8067
Homologene: 1901
Sec31a
Name: Sec31 homolog A (S. cerevisiae)
Synonyms: 1810024J13Rik, Sec31l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 69162
Homologene: 42056
Dhx37
Name: DEAH (Asp-Glu-Ala-His) box polypeptide 37
Synonyms: LOC381671, LOC208144
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 208144
Homologene: 6641
Trpa1
Name: transient receptor potential cation channel, subfamily A, member 1
Synonyms: ANKTM1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 277328
HGNC: HGNC:497
Homologene: 7189
Ppp1r12b
Name: protein phosphatase 1, regulatory subunit 12B
Synonyms: 1810037O03Rik, 9530009M10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 329251
HGNC: HGNC:7619
Homologene: 135710
Rdh10
Name: retinol dehydrogenase 10 (all-trans)
Synonyms: 3110069K09Rik, 4921506A21Rik, D1Ertd762e, m366Asp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 98711
Homologene: 14061
Abcb4
Name: ATP-binding cassette, sub-family B (MDR/TAP), member 4
Synonyms: Mdr2, Pgy-2, Pgy2, mdr-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 18670
HGNC: HGNC:45
Homologene: 136368
Ptprq
Name: protein tyrosine phosphatase, receptor type, Q
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 237523
HGNC: HGNC:9679
Homologene: 83557
Nalcn
Name: sodium leak channel, non-selective
Synonyms: Vgcnl1, A530023G15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 338370
VEGA: 14
Homologene: 21832
Skint5
Name: selection and upkeep of intraepithelial T cells 5
Synonyms: OTTMUSG00000008560
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242627
Homologene: 135888
Slc25a30
Name: solute carrier family 25, member 30
Synonyms: KMCP1, 4933433D23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 67554
VEGA: 14
Homologene: 57046
Sult1e1
Name: sulfotransferase family 1E, member 1
Synonyms: EST, Ste
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 20860
Homologene: 101388
Atp6v0d2
Name: ATPase, H+ transporting, lysosomal V0 subunit D2
Synonyms: 1620401A02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242341
Homologene: 72090
Itgb7
Name: integrin beta 7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 16421
HGNC: HGNC:6162
Homologene: 20247
Abca14
Name: ATP-binding cassette, sub-family A (ABC1), member 14
Synonyms: 4930539G24Rik, 1700110B15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 67928
Homologene: 86128
Fam149a
Name: family with sequence similarity 149, member A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 212326
Homologene: 27540
Obox3
Name: oocyte specific homeobox 3
Synonyms: Ohx
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 246791
Homologene: 44937
Clcn4
Name: chloride channel, voltage-sensitive 4
Synonyms: Clc4-2, Clcn4-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 12727
HGNC: HGNC:2022
Homologene: 68207
Olfr134
Name: olfactory receptor 134
Synonyms: MOR256-5, GA_x6K02T2PSCP-2623613-2624551
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 258829
Homologene: 110603
Mpl
Name: myeloproliferative leukemia virus oncogene
Synonyms: TPO-R, hlb219, thrombopoietin receptor, c-mpl-II, c-mpl-I, c-mpl, CD110
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 17480
HGNC: HGNC:7217
Homologene: 7845
Aars2
Name: alanyl-tRNA synthetase 2, mitochondrial
Synonyms: Aarsl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224805
VEGA: 17
Homologene: 56897
Myom3
Name: myomesin family, member 3
Synonyms: 8430427K15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242702
Homologene: 19432
Fut9
Name: fucosyltransferase 9
Synonyms: mFuc-TIX, mFUT9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 14348
HGNC: HGNC:4020
Homologene: 4800
Vps16
Name: VSP16 CORVET/HOPS core subunit
Synonyms: 1810074M16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 80743
Homologene: 7116
Zbtb22
Name: zinc finger and BTB domain containing 22
Synonyms: 1110008J20Rik, Bing1, Zfp297
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 81630
Homologene: 3982
Rnf8
Name: ring finger protein 8
Synonyms: AIP37, 3830404E21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 58230
Homologene: 2944
Ccdc190
Name: coiled-coil domain containing 190
Synonyms: 1700084C01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 78465
Homologene: 52274
Pigb
Name: phosphatidylinositol glycan anchor biosynthesis, class B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 55981
HGNC: HGNC:8959
Homologene: 3570
Pla2g2a
Name: phospholipase A2, group IIA (platelets, synovial fluid)
Synonyms: EF, Enhancing factor, modifier of Min1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 18780
HGNC: HGNC:9031
Gm12256
Name: predicted gene 12256
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Gm6644
Name: predicted gene 6644
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 626009
Ighv1-70
Name: immunoglobulin heavy variable 1-70
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 638634
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 14,881,661 bp
  • A to T, chromosome 1 at 16,107,997 bp
  • T to A, chromosome 1 at 55,444,631 bp
  • T to C, chromosome 1 at 134,886,428 bp
  • T to C, chromosome 1 at 138,175,084 bp
  • A to G, chromosome 1 at 169,933,009 bp
  • T to A, chromosome 2 at 24,192,786 bp
  • G to A, chromosome 2 at 29,978,443 bp
  • T to A, chromosome 2 at 121,981,293 bp
  • C to T, chromosome 2 at 130,441,279 bp
  • A to T, chromosome 3 at 102,520,129 bp
  • T to C, chromosome 4 at 19,878,292 bp
  • T to A, chromosome 4 at 25,620,731 bp
  • T to G, chromosome 4 at 107,375,165 bp
  • A to T, chromosome 4 at 113,742,212 bp
  • T to G, chromosome 4 at 118,456,684 bp
  • T to C, chromosome 4 at 126,687,090 bp
  • T to A, chromosome 4 at 135,765,586 bp
  • T to G, chromosome 4 at 138,833,284 bp
  • A to G, chromosome 5 at 8,959,176 bp
  • A to G, chromosome 5 at 65,808,462 bp
  • A to T, chromosome 5 at 87,587,594 bp
  • A to T, chromosome 5 at 100,393,321 bp
  • A to T, chromosome 5 at 125,415,152 bp
  • G to A, chromosome 7 at 7,291,619 bp
  • T to C, chromosome 7 at 15,627,309 bp
  • T to C, chromosome 7 at 80,743,068 bp
  • A to T, chromosome 7 at 120,253,429 bp
  • T to C, chromosome 7 at 141,151,771 bp
  • A to G, chromosome 8 at 13,009,715 bp
  • T to G, chromosome 8 at 45,350,435 bp
  • T to C, chromosome 9 at 73,022,401 bp
  • T to C, chromosome 10 at 26,303,688 bp
  • T to C, chromosome 10 at 93,065,197 bp
  • T to A, chromosome 10 at 107,534,704 bp
  • A to G, chromosome 11 at 12,256,198 bp
  • T to C, chromosome 11 at 53,588,751 bp
  • G to A, chromosome 11 at 58,889,845 bp
  • T to C, chromosome 11 at 70,945,005 bp
  • A to G, chromosome 11 at 70,947,719 bp
  • T to C, chromosome 12 at 115,692,101 bp
  • A to G, chromosome 14 at 21,669,986 bp
  • A to T, chromosome 14 at 75,771,516 bp
  • T to C, chromosome 14 at 123,515,737 bp
  • T to C, chromosome 15 at 102,217,029 bp
  • T to C, chromosome 17 at 29,641,254 bp
  • C to T, chromosome 17 at 33,918,449 bp
  • G to A, chromosome 17 at 34,911,664 bp
  • T to A, chromosome 17 at 38,175,454 bp
  • C to T, chromosome 17 at 45,514,829 bp
  • A to G, chromosome 18 at 80,137,543 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5158 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

For more information about this colony's health status contact mmrrc@missouri.edu
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

When this strain becomes available, Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

- Products for this strain are Not Yet Available for Ordering
- If you register interest in this strain, you will be notified when it becomes available for ordering.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.