Strain Name:
C57BL/6J-MtgxR5160Btlr/Mmmh
Stock Number:
042742-MU
Citation ID:
RRID:MMRRC_042742-MU
Other Names:
R5160 (G1), C57BL/6J-MtgxR5160Btlr
Major Collection:

Gene Information

Kifc2
Name: kinesin family member C2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 16581
VEGA: 15
Homologene: 7800
Tk1
Name: thymidine kinase 1
Synonyms: Tk-1, D530002A18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 21877
Homologene: 37749
Apoa5
Name: apolipoprotein A-V
Synonyms: RAP3, Apoav, 1300007O05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 66113
Homologene: 14197
Upp1
Name: uridine phosphorylase 1
Synonyms: UdRPase, UPase, Up
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 22271
Homologene: 2524
Lcor
Name: ligand dependent nuclear receptor corepressor
Synonyms: 3110023F06Rik, Mlr2, A630025C20Rik, LOC381224, Gm340
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 212391
VEGA: 19
Homologene: 18153
Ptpn12
Name: protein tyrosine phosphatase, non-receptor type 12
Synonyms: P19-PTP, PTP-PEST, PTP-P19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 19248
HGNC: HGNC:9645
Homologene: 37691
Jpt1
Name: Jupiter microtubule associated homolog 1
Synonyms: Hn1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 15374
Homologene: 7364
Zmym4
Name: zinc finger, MYM-type 4
Synonyms: 6330503C17Rik, Zfp262
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 67785
Homologene: 35470
Zc3h4
Name: zinc finger CCCH-type containing 4
Synonyms: LOC330474, Bwq1, Kiaa1064-hp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 330474
Homologene: 87150
Katnb1
Name: katanin p80 (WD40-containing) subunit B 1
Synonyms: KAT, 2410003J24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 74187
HGNC: HGNC:6217
Homologene: 4302
Pi4ka
Name: phosphatidylinositol 4-kinase alpha
Synonyms: Pik4ca
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 224020
HGNC: HGNC:8983
Homologene: 11171
Zc3h3
Name: zinc finger CCCH type containing 3
Synonyms: Smicl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223642
VEGA: 15
Homologene: 9029
Akap9
Name: A kinase (PRKA) anchor protein (yotiao) 9
Synonyms: AKAP450, 5730481H23Rik, G1-448-15, repro12, mei2-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100986
HGNC: HGNC:379
Homologene: 134583
Wls
Name: wntless WNT ligand secretion mediator
Synonyms: 5031439A09Rik, Gpr177
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 68151
Homologene: 11779
Arhgap42
Name: Rho GTPase activating protein 42
Synonyms: 9030420J04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 71544
Homologene: 28446
Myo9a
Name: myosin IXa
Synonyms: 4732465J09Rik, C130068I12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 270163
HGNC: HGNC:7608
Homologene: 21371
Ddx18
Name: DEAD box helicase 18
Synonyms: 2310005B10Rik, DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 66942
HGNC: HGNC:2741
Homologene: 6697
Bicc1
Name: BicC family RNA binding protein 1
Synonyms: Bic-C, jcpk
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 83675
Homologene: 12856
Apob
Name: apolipoprotein B
Synonyms: apob-100, apob-48
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 238055
HGNC: HGNC:603
Homologene: 328
Aftph
Name: aftiphilin
Synonyms: 9130023F12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216549
Homologene: 9764
Rb1
Name: RB transcriptional corepressor 1
Synonyms: pRb, Rb, Rb-1, retinoblastoma 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 19645
HGNC: HGNC:9884
Homologene: 272
Limk2
Name: LIM motif-containing protein kinase 2
Synonyms: Limk2b, Limk2a, A930024P04Rik, LIM kinase 2, whe
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 16886
HGNC: HGNC:6614
Homologene: 55911
Luc7l
Name: Luc7-like
Synonyms: 2410018D03Rik, 1810045C04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 66978
HGNC: HGNC:6723
Homologene: 100558
Osbpl7
Name: oxysterol binding protein-like 7
Synonyms: 4933437E18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 71240
Homologene: 79672
Magi3
Name: membrane associated guanylate kinase, WW and PDZ domain containing 3
Synonyms: 4732496O19Rik, 6530407C02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 99470
Homologene: 26431
Dnaja3
Name: DnaJ heat shock protein family (Hsp40) member A3
Synonyms: Tid-1, 1200003J13Rik, 1810053A11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 83945
Homologene: 36170
Dna2
Name: DNA replication helicase/nuclease 2
Synonyms: E130315B21Rik, Dna2l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 327762
HGNC: HGNC:2939
Homologene: 6124
Kdm6b
Name: KDM1 lysine (K)-specific demethylase 6B
Synonyms: Jmjd3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216850
Homologene: 18945
Olfr1413
Name: olfactory receptor 1413
Synonyms: GA_x6K02T2R7CC-81180849-81179878, MOR208-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 259039
Homologene: 128165
Mdh1b
Name: malate dehydrogenase 1B, NAD (soluble)
Synonyms: 1700124B08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 76668
Homologene: 57110
Zfp790
Name: zinc finger protein 790
Synonyms: 6330581L23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233056
Homologene: 51695
Ryr3
Name: ryanodine receptor 3
Synonyms: calcium release channel isoform 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20192
Homologene: 68151
Olfr209
Name: olfactory receptor 209
Synonyms: GA_x54KRFPKG5P-55590495-55589578, MOR182-6, MOR182-6, GA_x54KRFPKG5P-55580232-55579315, Olfr208
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 404311
Homologene: 133040
Zscan20
Name: zinc finger and SCAN domains 20
Synonyms: Zfp31
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 269585
Homologene: 51463
Ttc23l
Name: tetratricopeptide repeat domain 23-like
Synonyms: 4930401A09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 75777
Homologene: 44907
Col6a5
Name: collagen, type VI, alpha 5
Synonyms: Col6a5, Gm7455
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 665033
Homologene: 122792
Ina
Name: internexin neuronal intermediate filament protein, alpha
Synonyms: NF-66, NF66
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 226180
HGNC: HGNC:6057
Homologene: 10433
Il18
Name: interleukin 18
Synonyms: Il-18, Igif
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 16173
VEGA: 9
HGNC: HGNC:5986
Homologene: 1200
Kmt2d
Name: lysine (K)-specific methyltransferase 2D
Synonyms: C430014K11Rik, Mll4, Mll2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 381022
HGNC: HGNC:7133
Homologene: 86893
Cdh2
Name: cadherin 2
Synonyms: N-cadherin, Ncad, N-CAD
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 12558
HGNC: HGNC:1759
Homologene: 20424
Ano9
Name: anoctamin 9
Synonyms: 5430425C04Rik, Tp53i5, Trp53i5, Tmem16j
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 71345
Homologene: 67083
Oas1h
Name: 2'-5' oligoadenylate synthetase 1H
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 246729
HGNC: HGNC:8086
Homologene: 77345
Olfr1382
Name: olfactory receptor 1382
Synonyms: GA_x6K02T2QP88-5901165-5900230, MOR256-43P, MOR256-57
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 257971
Spice1
Name: spindle and centriole associated protein 1
Synonyms: D16Ertd480e, Ccdc52
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 212514
Homologene: 16931
Fnip2
Name: folliculin interacting protein 2
Synonyms: D630023B12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 329679
Homologene: 46417
Vmn1r30
Name: vomeronasal 1 receptor 30
Synonyms: V1rc9, V1rc22
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 171195
Homologene: 137652
Wdr35
Name: WD repeat domain 35
Synonyms: 4930459M12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 74682
Homologene: 10814
Ngly1
Name: N-glycanase 1
Synonyms: 1110002C09Rik, Png1, PNGase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 59007
Homologene: 10117
Prkcz
Name: protein kinase C, zeta
Synonyms: Pkcz, zetaPKC, aPKCzeta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 18762
HGNC: HGNC:9412
Homologene: 55681
Cfap100
Name: cilia and flagella associated protein 100
Synonyms: C030041G11Rik, C230069K22Rik, Ccdc37
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 243538
Homologene: 18456
Iffo1
Name: intermediate filament family orphan 1
Synonyms: 4733401N06Rik, Iffo, A930037G23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 320678
Homologene: 18706
Olfr91
Name: olfactory receptor 91
Synonyms: MOR256-20, GA_x6K02T2PSCP-1533927-1532989
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 258470
HGNC: HGNC:8252
Homologene: 72346
Mrps22
Name: mitochondrial ribosomal protein S22
Synonyms: Rpms22, 3100002P07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 64655
Homologene: 57030
Olfr364-ps1
Name: olfactory receptor 364, pseudogene 1
Synonyms: GA_x6K02T2NLDC-33831282-33832243, MOR138-4P, MOR138-7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227794
HGNC: HGNC:8216
Zfp873
Name: zinc finger protein 873
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 408062
Homologene: 134319
Rnaseh2b
Name: ribonuclease H2, subunit B
Synonyms: 2610207P08Rik, Dleu8, 1110019N06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 67153
Homologene: 41572
Olfr1252
Name: olfactory receptor 1252
Synonyms: GA_x6K02T2Q125-51162884-51161940, MOR231-22_p
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 404331
Homologene: 128094
Col8a2
Name: collagen, type VIII, alpha 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 329941
HGNC: HGNC:2216
Homologene: 55879
Pcdha3
Name: protocadherin alpha 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 192163
HGNC: HGNC:8669
Homologene: 129613
Peds1
Name: plasmanylethanolamine desaturase 1
Synonyms: Tmem189
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 407243
Homologene: 33615
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to T, chromosome 1 at 63,725,645 bp
  • C to T, chromosome 1 at 92,573,822 bp
  • A to G, chromosome 1 at 121,565,879 bp
  • T to A, chromosome 2 at 37,146,803 bp
  • T to C, chromosome 2 at 89,721,419 bp
  • A to T, chromosome 2 at 112,646,927 bp
  • A to T, chromosome 2 at 167,645,010 bp
  • G to A, chromosome 3 at 79,488,991 bp
  • T to A, chromosome 3 at 104,027,908 bp
  • C to T, chromosome 3 at 159,909,695 bp
  • A to G, chromosome 4 at 126,310,412 bp
  • A to T, chromosome 4 at 126,870,184 bp
  • A to G, chromosome 4 at 128,592,482 bp
  • A to T, chromosome 4 at 155,293,232 bp
  • A to G, chromosome 5 at 4,030,007 bp
  • T to A, chromosome 5 at 20,997,831 bp
  • A to G, chromosome 5 at 120,871,082 bp
  • T to A, chromosome 6 at 58,435,383 bp
  • A to G, chromosome 6 at 90,413,710 bp
  • T to G, chromosome 6 at 125,152,564 bp
  • T to C, chromosome 7 at 16,434,648 bp
  • C to T, chromosome 7 at 29,829,767 bp
  • G to A, chromosome 7 at 141,104,365 bp
  • G to T, chromosome 8 at 95,095,470 bp
  • T to G, chromosome 9 at 8,997,655 bp
  • A to G, chromosome 9 at 46,270,496 bp
  • G to A, chromosome 9 at 50,577,893 bp
  • T to C, chromosome 9 at 59,871,802 bp
  • T to C, chromosome 9 at 98,596,922 bp
  • T to C, chromosome 9 at 105,931,009 bp
  • T to C, chromosome 10 at 62,947,154 bp
  • T to C, chromosome 10 at 70,932,236 bp
  • C to T, chromosome 10 at 82,061,042 bp
  • A to C, chromosome 11 at 3,350,772 bp
  • T to C, chromosome 11 at 9,135,193 bp
  • G to A, chromosome 11 at 20,712,197 bp
  • T to C, chromosome 11 at 49,535,689 bp
  • C to A, chromosome 11 at 69,400,768 bp
  • T to C, chromosome 11 at 97,054,556 bp
  • T to A, chromosome 11 at 115,500,619 bp
  • A to G, chromosome 11 at 117,824,746 bp
  • T to C, chromosome 12 at 8,012,126 bp
  • C to T, chromosome 12 at 9,008,487 bp
  • A to G, chromosome 14 at 16,281,751 bp
  • T to G, chromosome 14 at 62,353,531 bp
  • A to G, chromosome 14 at 73,264,455 bp
  • G to T, chromosome 15 at 10,551,550 bp
  • A to T, chromosome 15 at 75,809,663 bp
  • T to A, chromosome 15 at 76,662,977 bp
  • A to G, chromosome 15 at 98,840,224 bp
  • T to A, chromosome 16 at 4,684,288 bp
  • T to C, chromosome 16 at 17,323,053 bp
  • T to C, chromosome 16 at 44,370,026 bp
  • C to T, chromosome 16 at 59,361,766 bp
  • A to G, chromosome 17 at 26,267,297 bp
  • T to C, chromosome 17 at 37,093,724 bp
  • A to T, chromosome 18 at 16,629,587 bp
  • T to C, chromosome 18 at 36,946,427 bp
  • T to A, chromosome 19 at 41,555,614 bp
  • T to A, chromosome 19 at 47,015,080 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5160 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
042742-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.