Strain Name:
C57BL/6J-MtgxR5164Btlr/Mmmh
Stock Number:
042745-MU
Citation ID:
RRID:MMRRC_042745-MU
Other Names:
R5164 (G1), C57BL/6J-MtgxR5164Btlr
Major Collection:

Gene Information

Ebf2
Name: early B cell factor 2
Synonyms: O/E-3, D14Ggc1e, Mmot1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 13592
Homologene: 56471
Chrnb3
Name: cholinergic receptor, nicotinic, beta polypeptide 3
Synonyms: Acrb3, 5730417K16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 108043
HGNC: HGNC:1963
Homologene: 36035
Tpst1
Name: protein-tyrosine sulfotransferase 1
Synonyms: Tango13a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 22021
Homologene: 2667
Cwf19l2
Name: CWF19-like 2, cell cycle control (S. pombe)
Synonyms: 3230401L03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 244672
Homologene: 12366
Dock5
Name: dedicator of cytokinesis 5
Synonyms: lr2, 1110060D06Rik, rlc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 68813
VEGA: 14
Homologene: 57016
Fkbp5
Name: FK506 binding protein 5
Synonyms: FKBP51, Dit1, D17Ertd592e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 14229
HGNC: HGNC:3721
Homologene: 3038
Atad5
Name: ATPase family, AAA domain containing 5
Synonyms: LOC237877, C130052G03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237877
Homologene: 32611
Ythdf3
Name: YTH N6-methyladenosine RNA binding protein 3
Synonyms: 9130022A11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229096
Homologene: 34991
Kif1b
Name: kinesin family member 1B
Synonyms: D4Mil1e, Kif1b alpha, Kif1b beta, KIF1Bp130, KIF1Bp204, N-3 kinesin, A530096N05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 16561
Homologene: 99835
Cse1l
Name: chromosome segregation 1-like (S. cerevisiae)
Synonyms: Cas, Capts, 2610100P18Rik, Xpo2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 110750
HGNC: HGNC:2431
Homologene: 1006
Cdkal1
Name: CDK5 regulatory subunit associated protein 1-like 1
Synonyms: 6620401C13Rik, 1190005B03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 68916
Homologene: 9830
Zc3h3
Name: zinc finger CCCH type containing 3
Synonyms: Smicl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223642
VEGA: 15
Homologene: 9029
Hectd1
Name: HECT domain E3 ubiquitin protein ligase 1
Synonyms: A630086P08Rik, opm, b2b327Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 207304
VEGA: 12
Homologene: 9115
Mdn1
Name: midasin AAA ATPase 1
Synonyms: LOC213784, 4833432B22Rik, D4Abb1e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100019
Homologene: 39689
Epha8
Name: Eph receptor A8
Synonyms: EphA8, Hek3, Eek
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 13842
HGNC: HGNC:3391
Homologene: 22436
Smarcd2
Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
Synonyms: Baf60b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 83796
Homologene: 20671
Tcf20
Name: transcription factor 20
Synonyms: SPBP, stromelysin 1 PDGF responsive element binding protein, 2810438H08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 21411
VEGA: 15
Homologene: 4131
Egfr
Name: epidermal growth factor receptor
Synonyms: avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, Erbb, Wa5, 9030024J15Rik, Errb1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 13649
HGNC: HGNC:3236
Homologene: 74545
Pms1
Name: PMS1 homolog 1, mismatch repair system component
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227099
HGNC: HGNC:9121
Homologene: 449
Pnisr
Name: PNN interacting serine/arginine-rich
Synonyms: 5730406M06Rik, Sfrs18
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 66625
Homologene: 32802
Unkl
Name: unkempt family like zinc finger
Synonyms: 1300004G08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 74154
Homologene: 62673
Zfp268
Name: zinc finger protein 268
Synonyms: Gm13212
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 433801
Homologene: 133076
Usf3
Name: upstream transcription factor family member 3
Synonyms: LOC207806, LOC385650, 5530400K22Rik, Gm608
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 207806
Homologene: 19504
Akap6
Name: A kinase (PRKA) anchor protein 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 238161
VEGA: 12
HGNC: HGNC:376
Homologene: 3157
Dnah5
Name: dynein, axonemal, heavy chain 5
Synonyms: Mdnah5, b2b1537Clo, b2b1565Clo, b2b1154Clo, b2b1134Clo, Dnahc5, b2b3491Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 110082
HGNC: HGNC:2950
Homologene: 1048
Ptprd
Name: protein tyrosine phosphatase, receptor type, D
Synonyms: 3000002J10Rik, B230219D21Rik, 1110002J03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 19266
HGNC: HGNC:9668
Adgrv1
Name: adhesion G protein-coupled receptor V1
Synonyms: VLGR1, Mass1, Mgr1, Gpr98
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 110789
Homologene: 19815
Ufm1
Name: ubiquitin-fold modifier 1
Synonyms: 1810045K17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 67890
Homologene: 9594
Cfap44
Name: cilia and flagella associated protein 44
Synonyms: 6330444M21Rik, D16Ertd642e, Wdr52
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 212517
Homologene: 75085
Ppargc1b
Name: peroxisome proliferative activated receptor, gamma, coactivator 1 beta
Synonyms: PGC-1beta/ERRL1, 4631412G21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 170826
Homologene: 15776
Odad4
Name: outer dynein arm complex subunit 4
Synonyms: 4933404O19Rik, Ttc25
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 74407
Homologene: 12860
Gramd4
Name: GRAM domain containing 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223752
Homologene: 18199
Cfap65
Name: cilia and flagella associated protein 65
Synonyms: B230363K08Rik, Ccdc108
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 241116
Homologene: 28093
Keg1
Name: kidney expressed gene 1
Synonyms: GS4059, 0610008P16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 64697
Homologene: 69461
Slc14a2
Name: solute carrier family 14 (urea transporter), member 2
Synonyms: UT-A3, UT-A5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 27411
VEGA: 18
Homologene: 5183
Gbp4
Name: guanylate binding protein 4
Synonyms: Mag-2, Mpa-2, Mpa2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 17472
Homologene: 128731
Fam20c
Name: FAM20C, golgi associated secretory pathway kinase
Synonyms: DMP4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 80752
Homologene: 56879
Dnase2a
Name: deoxyribonuclease II alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 13423
HGNC: HGNC:2960
Homologene: 68179
Lilra6
Name: leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
Synonyms: 7M1, Pira3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 18726
HGNC: HGNC:6609
Homologene: 134028
Nrd1
Name: nardilysin, N-arginine dibasic convertase, NRD convertase 1
Synonyms: NRD-C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230598
HGNC: HGNC:7995
Homologene: 68260
Spag6l
Name: sperm associated antigen 6-like
Synonyms: PF16, Spag6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 50525
Homologene: 8252
Slc23a2
Name: solute carrier family 23 (nucleobase transporters), member 2
Synonyms: YSPL3, SVCT2, Slc23a1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 54338
Homologene: 68440
Slc47a1
Name: solute carrier family 47, member 1
Synonyms: 1300013J15Rik, MATE1, mMATE1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 67473
Homologene: 34364
Or8k24
Name: olfactory receptor family 8 subfamily K member 24
Synonyms: GA_x6K02T2Q125-47855818-47854868, MOR190-2, Olfr1058
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258386
Homologene: 74093
Fam126b
Name: family with sequence similarity 126, member B
Synonyms: D1Ertd53e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 213056
Homologene: 18184
Pp2d1
Name: protein phosphatase 2C-like domain containing 1
Synonyms: 4921523A10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 110332
VEGA: 17
Homologene: 16981
Arsj
Name: arylsulfatase J
Synonyms: 9330196J05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 271970
Homologene: 35257
Or5p6
Name: olfactory receptor family 5 subfamily P member 6
Synonyms: GA_x6K02T2PBJ9-10361879-10360935, MOR204-13, Olfr478
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258729
Homologene: 128076
H2-Ke6
Name: H2-K region expressed gene 6
Synonyms: Ring2, H-2Ke6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 14979
HGNC: HGNC:3554
Homologene: 56588
Or4c106
Name: olfactory receptor family 4 subfamily C member 106
Synonyms: GA_x6K02T2Q125-50322618-50323547, MOR232-6, Olfr1204
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258455
Homologene: 133021
Runx3
Name: runt related transcription factor 3
Synonyms: AML2, Cbfa3, Rx3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 12399
Homologene: 37914
Serpina1b
Name: serine (or cysteine) preptidase inhibitor, clade A, member 1B
Synonyms: PI2, D12Ucla2, Spi1-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 20701
HGNC: HGNC:8941
Homologene: 20103
Igkv4-80
Name: immunoglobulin kappa variable 4-80
Synonyms: Gm16729
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 545848
Gm26796
Name: predicted gene, 26796
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 53,207,640 bp
  • T to C, chromosome 1 at 58,535,438 bp
  • T to C, chromosome 1 at 74,926,516 bp
  • A to G, chromosome 2 at 18,698,499 bp
  • T to C, chromosome 2 at 86,385,471 bp
  • T to A, chromosome 2 at 88,852,570 bp
  • T to A, chromosome 2 at 132,075,450 bp
  • C to A, chromosome 2 at 166,944,428 bp
  • T to C, chromosome 3 at 16,183,513 bp
  • A to C, chromosome 3 at 53,857,927 bp
  • A to T, chromosome 3 at 126,438,159 bp
  • A to T, chromosome 4 at 21,859,237 bp
  • A to G, chromosome 4 at 32,759,011 bp
  • T to C, chromosome 4 at 76,100,758 bp
  • C to T, chromosome 4 at 109,039,717 bp
  • T to C, chromosome 4 at 135,121,130 bp
  • T to C, chromosome 4 at 136,945,672 bp
  • T to C, chromosome 4 at 145,622,205 bp
  • A to G, chromosome 4 at 149,245,682 bp
  • T to A, chromosome 5 at 105,136,877 bp
  • T to A, chromosome 5 at 130,102,001 bp
  • C to A, chromosome 5 at 138,755,631 bp
  • A to C, chromosome 6 at 69,016,665 bp
  • A to T, chromosome 7 at 3,914,881 bp
  • G to A, chromosome 7 at 108,032,280 bp
  • T to A, chromosome 8 at 27,394,132 bp
  • A to G, chromosome 8 at 84,913,518 bp
  • T to C, chromosome 9 at 3,475,511 bp
  • G to T, chromosome 11 at 16,909,872 bp
  • A to G, chromosome 11 at 61,353,060 bp
  • G to A, chromosome 11 at 80,109,450 bp
  • G to A, chromosome 11 at 100,571,520 bp
  • C to T, chromosome 11 at 106,266,900 bp
  • C to A, chromosome 12 at 51,827,489 bp
  • A to G, chromosome 12 at 53,142,466 bp
  • T to C, chromosome 12 at 80,758,562 bp
  • A to G, chromosome 12 at 103,732,087 bp
  • A to T, chromosome 13 at 29,625,719 bp
  • A to T, chromosome 13 at 81,435,674 bp
  • T to C, chromosome 14 at 67,390,521 bp
  • A to T, chromosome 14 at 67,817,661 bp
  • A to T, chromosome 15 at 28,408,292 bp
  • A to T, chromosome 15 at 75,777,026 bp
  • A to G, chromosome 15 at 82,856,603 bp
  • A to T, chromosome 15 at 86,100,831 bp
  • T to C, chromosome 16 at 44,218,180 bp
  • T to A, chromosome 16 at 44,481,389 bp
  • A to G, chromosome 17 at 25,213,109 bp
  • A to G, chromosome 17 at 28,437,990 bp
  • A to G, chromosome 17 at 34,026,978 bp
  • G to T, chromosome 17 at 53,508,070 bp
  • A to T, chromosome 18 at 61,302,644 bp
  • G to A, chromosome 18 at 78,157,272 bp
  • A to G, chromosome 19 at 12,714,680 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5164 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
042745-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.