Strain Name:
C57BL/6J-MtgxR5185Btlr/Mmmh
Stock Number:
042764-MU
Citation ID:
RRID:MMRRC_042764-MU
Other Names:
R5185 (G1), C57BL/6J-MtgxR5185Btlr
Major Collection:

Gene Information

Nfatc2
Name: nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2
Synonyms: NFAT1-D, NFAT1, NFATp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 18019
HGNC: HGNC:7776
Homologene: 7861
Gpd2
Name: glycerol phosphate dehydrogenase 2, mitochondrial
Synonyms: Gdm1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 14571
HGNC: HGNC:4456
Homologene: 352
Btc
Name: betacellulin, epidermal growth factor family member
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 12223
HGNC: HGNC:1121
Homologene: 1309
Thbs4
Name: thrombospondin 4
Synonyms: TSP4, TSP-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 21828
Homologene: 20691
Atp6v1h
Name: ATPase, H+ transporting, lysosomal V1 subunit H
Synonyms: 0710001F19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 108664
Homologene: 7139
Kmt2a
Name: lysine (K)-specific methyltransferase 2A
Synonyms: Mll, Mll1, All1, HTRX1, ALL-1, trithorax Drosophila, Cxxc7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 214162
HGNC: HGNC:7132
Homologene: 4338
Ap1g1
Name: adaptor protein complex AP-1, gamma 1 subunit
Synonyms: gamma-adaptin, D8Ertd374e, Adtg
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 11765
HGNC: HGNC:555
Homologene: 47995
Xdh
Name: xanthine dehydrogenase
Synonyms: xanthine oxidase, Xox-1, XO, Xox1, Xor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 22436
VEGA: 17
Homologene: 324
Tg
Name: thyroglobulin
Synonyms: Tgn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 21819
Homologene: 2430
Dffa
Name: DNA fragmentation factor, alpha subunit
Synonyms: A330085O09Rik, DFF35, Dff45, ICAD-S, ICAD-L
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 13347
HGNC: HGNC:2772
Homologene: 3240
Fcho1
Name: FCH domain only 1
Synonyms: 3322402E17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 74015
Homologene: 22869
Bcl6
Name: B cell leukemia/lymphoma 6
Synonyms: Bcl5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 12053
HGNC: HGNC:1001
Homologene: 7640
Fndc3b
Name: fibronectin type III domain containing 3B
Synonyms: 1600019O04Rik, fad104
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 72007
Homologene: 11244
Nlrp3
Name: NLR family, pyrin domain containing 3
Synonyms: cryopyrin, Mmig1, NALP3, Cias1, Pypaf1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 216799
Homologene: 3600
Acsf2
Name: acyl-CoA synthetase family member 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 264895
Homologene: 23519
Brd3
Name: bromodomain containing 3
Synonyms: Fsrg2, 2410084F24Rik, RINGL3, ORFX
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 67382
HGNC: HGNC:1104
Homologene: 81801
Tut1
Name: terminal uridylyl transferase 1, U6 snRNA-specific
Synonyms: 2700038E08Rik, PAPD2, TUTase6, Rbm21, Tent1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 70044
VEGA: 19
Homologene: 69361
Ccdc171
Name: coiled-coil domain containing 171
Synonyms: 4930418J05Rik, A330015D16Rik, 4930473A06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 320226
Homologene: 27942
Efl1
Name: elongation factor like GTPase 1
Synonyms: Eftud1, 4932434J20Rik, 6030468D11Rik, D7Ertd791e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 101592
Homologene: 11599
Tpcn2
Name: two pore segment channel 2
Synonyms: D830047E22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233979
Homologene: 16375
Pcdhb16
Name: protocadherin beta 16
Synonyms: Pcdhb8, PcdhbP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 93887
HGNC: HGNC:8693
Homologene: 99843
Dnhd1
Name: dynein heavy chain domain 1
Synonyms: 8030491N06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 77505
Homologene: 131117
Spink5
Name: serine peptidase inhibitor, Kazal type 5
Synonyms: LEKT1, 2310065D10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 72432
Homologene: 4987
Ttn
Name: titin
Synonyms: shru, connectin, mdm, 2310057K23Rik, D330041I19Rik, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, L56, 2310074I15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 22138
Homologene: 130650
Hmcn1
Name: hemicentin 1
Synonyms: LOC240793, EG545370
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 545370
Homologene: 23741
Spata31
Name: spermatogenesis associated 31
Synonyms: Fam75a, 4930458L03Rik, Spata31a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 78124
Homologene: 84621
Svep1
Name: sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
Synonyms: 1110021D17Rik, 4833413O10Rik, Polydom, D430029O09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 64817
Homologene: 23386
Arsi
Name: arylsulfatase i
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 545260
Homologene: 44428
Ralgapa2
Name: Ral GTPase activating protein, alpha subunit 2 (catalytic)
Synonyms: AS250, RGC2, A230067G21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 241694
Homologene: 28131
Naip2
Name: NLR family, apoptosis inhibitory protein 2
Synonyms: Naip2, Birc1b, Naip-rs6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 17948
HGNC: HGNC:7634
Homologene: 136092
Cul9
Name: cullin 9
Synonyms: 1810035I07Rik, Parc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 78309
Homologene: 56696
Plpp4
Name: phospholipid phosphatase 4
Synonyms: Ppapdc1a, LOC381925, C030048B12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 381925
Homologene: 38751
Atxn7
Name: ataxin 7
Synonyms: Sca7, A430107N12Rik, ataxin-7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 246103
VEGA: 14
Homologene: 30967
Olfr1097
Name: olfactory receptor 1097
Synonyms: GA_x6K02T2Q125-48376288-48375341, MOR206-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258840
Homologene: 37005
Rasal3
Name: RAS protein activator like 3
Synonyms: A430107D22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 320484
Homologene: 18901
Golgb1
Name: golgi autoantigen, golgin subfamily b, macrogolgin 1
Synonyms: Giantin, Gm6840, 6330407A06Rik, C130074L01Rik, F730017E11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 224139
HGNC: HGNC:4429
Homologene: 68401
Pnmal2
Name: PNMA-like 2
Synonyms: EG434128
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 434128
Homologene: 35491
Il1rl2
Name: interleukin 1 receptor-like 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 107527
HGNC: HGNC:5999
Homologene: 2860
Rfx4
Name: regulatory factor X, 4 (influences HLA class II expression)
Synonyms: 4933412G19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 71137
HGNC: HGNC:9985
Homologene: 31119
Kif14
Name: kinesin family member 14
Synonyms: N-3 kinesin, D1Ertd367e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 381293
Homologene: 8916
Zfp108
Name: zinc finger protein 108
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 54678
Homologene: 117959
Kdr
Name: kinase insert domain protein receptor
Synonyms: VEGF receptor-2, vascular endothelial growth factor receptor- 2, Flk-1, orv, Flk1, VEGFR-2, VEGFR2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 16542
HGNC: HGNC:6307
Homologene: 55639
Aox4
Name: aldehyde oxidase 4
Synonyms: 2310003G12Rik, AOH2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 71872
Homologene: 70273
Bap1
Name: Brca1 associated protein 1
Synonyms: 2300006C11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 104416
HGNC: HGNC:950
Homologene: 3421
Arsb
Name: arylsulfatase B
Synonyms: As1-t, As-1, Ast-1, As1-r, As-1t, As1, 1110007C02Rik, As1-s, Asr-1, As-1s, As-1r
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 11881
VEGA: 13
HGNC: HGNC:714
Homologene: 73870
Efcab12
Name: EF-hand calcium binding domain 12
Synonyms: BC060267
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 212516
Homologene: 18905
Rad21l
Name: RAD21-like (S. pombe)
Synonyms: Gm14160
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 668929
Homologene: 82650
Lilra6
Name: leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
Synonyms: 7M1, Pira3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 18726
HGNC: HGNC:6607
Homologene: 134028
Slc28a2
Name: solute carrier family 28 (sodium-coupled nucleoside transporter), member 2
Synonyms: 2010208B10Rik, CNT2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 269346
Homologene: 20891
Olfr149
Name: olfactory receptor 149
Synonyms: M31, GA_x6K02T2PVTD-33400306-33399371, MOR224-8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235256
VEGA: 9
Homologene: 28452
Cfap43
Name: cilia and flagella associated protein 43
Synonyms: 4930428C11Rik, Wdr96, D19Ertd652e, 4930463G05Rik, 4632415N18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 100048534
Homologene: 36425
Grip1
Name: glutamate receptor interacting protein 1
Synonyms: eb, 4931400F03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 74053
Homologene: 12938
Try10
Name: trypsin 10
Synonyms: trypsinogen 10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 436522
HGNC: HGNC:9475
Homologene: 134623
Krt15
Name: keratin 15
Synonyms: K15, Krt1-15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 16665
HGNC: HGNC:6421
Homologene: 1712
Mpp4
Name: membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
Synonyms: DLG6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 227157
Homologene: 23296
Vmn1r17
Name: vomeronasal 1 receptor 17
Synonyms: V1rc16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 171189
Homologene: 115643
Olfr1230
Name: olfactory receptor 1230
Synonyms: GA_x6K02T2Q125-50741934-50741017, MOR237-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258785
Homologene: 81570
Nek5
Name: NIMA (never in mitosis gene a)-related expressed kinase 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 330721
HGNC: HGNC:7748
Homologene: 87952
Olfr58
Name: olfactory receptor 58
Synonyms: MOR146-3, MOR146-7P, IG6, GA_x6K02T2PVTD-13523015-13523944
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 18358
Homologene: 134093
Rnf19b
Name: ring finger protein 19B
Synonyms: 4930555L03Rik, Ibrdc3, 4930534K13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 75234
Homologene: 34999
Lpcat2
Name: lysophosphatidylcholine acyltransferase 2
Synonyms: Aytl1a, LPCAT2, Aytl1, lysoPAFAT/LPCAT2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 270084
Homologene: 41201
Bak1
Name: BCL2-antagonist/killer 1
Synonyms: N-Bak, Bak
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 12018
HGNC: HGNC:949
Homologene: 917
Yipf4
Name: Yip1 domain family, member 4
Synonyms: 2310034L04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 67864
VEGA: 17
Homologene: 32658
Gm9949
Name: predicted gene 9949
Synonyms: EG225609
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 225609
VEGA: 18
Lactbl1
Name: lactamase, beta-like 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 242707
Homologene: 82492
Pnma2
Name: paraneoplastic antigen MA2
Synonyms: A830049P17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 239157
HGNC: HGNC:9159
Homologene: 5249
Htra2
Name: HtrA serine peptidase 2
Synonyms: Prss25, OMI, mnd2, HtrA2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 64704
Homologene: 113300
Hsd17b1
Name: hydroxysteroid (17-beta) dehydrogenase 1
Synonyms: Hsd17ba, 17beta-HSD
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 15485
HGNC: HGNC:5210
Homologene: 37303
Gm6189
Name: predicted gene 6189
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 620899
Gm5108
Name: predicted gene 5108
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 330097
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 5,095,642 bp
  • T to C, chromosome 1 at 40,326,509 bp
  • T to C, chromosome 1 at 58,254,318 bp
  • T to C, chromosome 1 at 59,125,583 bp
  • T to C, chromosome 1 at 80,384,231 bp
  • T to A, chromosome 1 at 136,527,469 bp
  • T to C, chromosome 1 at 150,656,741 bp
  • T to C, chromosome 2 at 27,462,448 bp
  • T to C, chromosome 2 at 57,340,204 bp
  • C to T, chromosome 2 at 76,939,221 bp
  • T to C, chromosome 2 at 86,890,602 bp
  • A to T, chromosome 2 at 89,296,387 bp
  • G to A, chromosome 2 at 122,458,194 bp
  • C to A, chromosome 2 at 146,388,486 bp
  • T to C, chromosome 2 at 151,657,462 bp
  • A to G, chromosome 2 at 168,570,707 bp
  • T to A, chromosome 3 at 27,457,070 bp
  • C to T, chromosome 4 at 58,084,534 bp
  • T to G, chromosome 4 at 83,663,655 bp
  • T to A, chromosome 4 at 129,083,920 bp
  • A to T, chromosome 4 at 136,631,045 bp
  • C to A, chromosome 4 at 149,117,430 bp
  • A to G, chromosome 5 at 67,944,610 bp
  • A to T, chromosome 5 at 75,952,417 bp
  • A to G, chromosome 5 at 91,362,277 bp
  • A to T, chromosome 6 at 41,356,549 bp
  • A to G, chromosome 6 at 57,360,843 bp
  • G to A, chromosome 6 at 83,054,242 bp
  • T to A, chromosome 6 at 115,823,490 bp
  • T to A, chromosome 7 at 3,914,636 bp
  • A to T, chromosome 7 at 16,945,976 bp
  • G to T, chromosome 7 at 24,260,738 bp
  • T to C, chromosome 7 at 82,772,499 bp
  • G to A, chromosome 7 at 105,703,209 bp
  • G to A, chromosome 7 at 129,316,304 bp
  • A to T, chromosome 7 at 145,255,454 bp
  • C to T, chromosome 8 at 22,083,381 bp
  • A to G, chromosome 8 at 71,714,956 bp
  • G to A, chromosome 8 at 92,869,737 bp
  • G to A, chromosome 8 at 109,863,326 bp
  • T to C, chromosome 9 at 19,783,376 bp
  • A to T, chromosome 9 at 39,701,876 bp
  • A to T, chromosome 9 at 44,820,246 bp
  • G to T, chromosome 10 at 84,863,250 bp
  • A to G, chromosome 10 at 92,921,381 bp
  • T to G, chromosome 10 at 119,931,259 bp
  • C to A, chromosome 11 at 59,565,084 bp
  • T to C, chromosome 11 at 94,562,911 bp
  • T to C, chromosome 11 at 100,133,433 bp
  • T to C, chromosome 11 at 101,080,198 bp
  • G to T, chromosome 13 at 64,917,526 bp
  • A to C, chromosome 13 at 92,775,167 bp
  • T to C, chromosome 13 at 93,794,159 bp
  • A to T, chromosome 13 at 100,189,351 bp
  • T to C, chromosome 14 at 14,090,063 bp
  • A to G, chromosome 14 at 31,248,037 bp
  • A to T, chromosome 14 at 66,916,129 bp
  • T to C, chromosome 15 at 66,773,474 bp
  • A to T, chromosome 16 at 23,972,947 bp
  • T to C, chromosome 16 at 36,875,141 bp
  • G to A, chromosome 17 at 27,022,748 bp
  • A to T, chromosome 17 at 32,396,790 bp
  • A to T, chromosome 17 at 46,525,832 bp
  • G to A, chromosome 17 at 73,925,011 bp
  • A to G, chromosome 17 at 74,492,475 bp
  • T to C, chromosome 18 at 37,480,089 bp
  • T to C, chromosome 18 at 44,015,644 bp
  • A to G, chromosome 18 at 60,916,912 bp
  • T to G, chromosome 18 at 62,180,565 bp
  • C to A, chromosome 19 at 8,955,450 bp
  • A to G, chromosome 19 at 47,780,394 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5185 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
042764-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.