Strain Name:
C57BL/6J-MtgxR5201Btlr/Mmmh
Stock Number:
042776-MU
Citation ID:
RRID:MMRRC_042776-MU
Other Names:
R5201 (G1), C57BL/6J-MtgxR5201Btlr
Major Collection:

Gene Information

Mrtfb
Name: myocardin related transcription factor B
Synonyms: Mrtfb, Gt4-1, MRTF-B, Mkl2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 239719
Homologene: 40917
Otx1
Name: orthodenticle homeobox 1
Synonyms: jv, A730044F23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 18423
HGNC: HGNC:8521
Homologene: 7875
Nfia
Name: nuclear factor I/A
Synonyms: 9430022M17Rik, 1110047K16Rik, NF1-A, NF1A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 18027
HGNC: HGNC:7784
Homologene: 4086
Macf1
Name: microtubule-actin crosslinking factor 1
Synonyms: trabeculin alpha, Aclp7, Acf7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 11426
Homologene: 136191
Actn4
Name: actinin alpha 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 60595
HGNC: HGNC:166
Homologene: 55857
Fzr1
Name: fizzy and cell division cycle 20 related 1
Synonyms: Cdh1, Fyr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 56371
Homologene: 9444
Hira
Name: histone cell cycle regulator
Synonyms: Tuple1, D16Ertd95e, Gm15797
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 15260
HGNC: HGNC:4916
Homologene: 48172
Drd5
Name: dopamine receptor D5
Synonyms: Drd-5, DRD1b, D5R, Drd1b, Gpcr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 13492
HGNC: HGNC:3026
Homologene: 20216
Myh10
Name: myosin, heavy polypeptide 10, non-muscle
Synonyms: Myosin IIB, nonmuscle myosin heavy chain IIB, Fltn, Myhn-2, SMemb, NMHC-B, nonmuscle myosin heavy chain II-B, 5730504C04Rik, 9330167F11Rik, Fltn, myosin IIB, NMHC II-B, Myhn2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 77579
HGNC: HGNC:7568
Homologene: 55941
Taf3
Name: TATA-box binding protein associated factor 3
Synonyms: 4933439M23Rik, mTAFII140
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 209361
Homologene: 35415
Ilf3
Name: interleukin enhancer binding factor 3
Synonyms: NF90
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 16201
VEGA: 9
HGNC: HGNC:6038
Homologene: 7785
Nup205
Name: nucleoporin 205
Synonyms: 3830404O05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 70699
Homologene: 45971
Arap2
Name: ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
Synonyms: Centd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 212285
Homologene: 9064
Tep1
Name: telomerase associated protein 1
Synonyms: Tp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 21745
VEGA: 14
Homologene: 5157
Rad50
Name: RAD50 double strand break repair protein
Synonyms: Mrell, Rad50l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 19360
HGNC: HGNC:9816
Homologene: 38092
Vps39
Name: VPS39 HOPS complex subunit
Synonyms: mVam6, Vam6, Vam6P, A230065P22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 269338
Homologene: 41025
Tpd52l2
Name: tumor protein D52-like 2
Synonyms: D54, 2810411G23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 66314
Homologene: 2469
Malt1
Name: MALT1 paracaspase
Synonyms: D430033E09Rik, paracaspase, Pcasp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 240354
HGNC: HGNC:6819
Homologene: 4938
Prr14l
Name: proline rich 14-like
Synonyms: C330019G07Rik, 6030436E02Rik, Prl14l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 215476
Homologene: 65866
Enpp6
Name: ectonucleotide pyrophosphatase/phosphodiesterase 6
Synonyms: Npp6, D8Ertd514e, 4833421B01Rik, B830047L21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 320981
Homologene: 62657
Wdr75
Name: WD repeat domain 75
Synonyms: 1300003A18Rik, 2410118I19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 73674
Homologene: 32771
Atl2
Name: atlastin GTPase 2
Synonyms: Arl6ip2, 2010110I21Rik, Aip-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 56298
VEGA: 17
Homologene: 56949
Olfml2b
Name: olfactomedin-like 2B
Synonyms: photomedin-2, 4832415H08Rik, 1110018N05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 320078
Homologene: 18546
Fgd3
Name: FYVE, RhoGEF and PH domain containing 3
Synonyms: 5830461L01Rik, ZFYVE5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 30938
Homologene: 22925
Man1a2
Name: mannosidase, alpha, class 1A, member 2
Synonyms: Man1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 17156
HGNC: HGNC:6822
Homologene: 55982
Itgae
Name: integrin alpha E, epithelial-associated
Synonyms: CD103, alpha-E1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 16407
HGNC: HGNC:6147
Homologene: 113560
Ercc5
Name: excision repair cross-complementing rodent repair deficiency, complementation group 5
Synonyms: Xpg
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 22592
HGNC: HGNC:3437
Homologene: 133551
Dnah6
Name: dynein, axonemal, heavy chain 6
Synonyms: Dnahc6, A730004I20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 330355
HGNC: HGNC:2951
Homologene: 15221
Prss46
Name: protease, serine 46
Synonyms: 1700112C13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 74306
Homologene: 77706
Zfp943
Name: zinc finger prtoein 943
Synonyms: 4930432O21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 74670
Homologene: 134342
Cyp2b10
Name: cytochrome P450, family 2, subfamily b, polypeptide 10
Synonyms: phenobarbitol inducible, type b, p16, Cyp2b20, Cyp2b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 13088
HGNC: HGNC:2615
Homologene: 73894
Tmod4
Name: tropomodulin 4
Synonyms: skeletal tropomodulin, MTMOD, Sk-Tmod
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 50874
Homologene: 8355
Vmn2r77
Name: vomeronasal 2, receptor 77
Synonyms: EG546983
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 546983
Homologene: 115466
Duox1
Name: dual oxidase 1
Synonyms: LNOX1, NOXEF1, THOX1, 9930101G15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 99439
HGNC: HGNC:3062
Homologene: 68136
4930407I10Rik
Name: RIKEN cDNA 4930407I10 gene
Synonyms: LOC328573
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 328573
VEGA: 15
Homologene: 130065
Cby2
Name: chibby family member 2
Synonyms: Spert, 1700086N05Rik, Nurit
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 67926
VEGA: 14
Homologene: 12213
Kif14
Name: kinesin family member 14
Synonyms: N-3 kinesin, D1Ertd367e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 381293
Homologene: 8916
Itprid1
Name: ITPR interacting domain containing 1
Synonyms: D530004J12Rik, Ccdc129
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232016
Homologene: 52344
Srrd
Name: SRR1 domain containing
Synonyms: 2810002G02Rik, Srr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 70118
Homologene: 33447
Dyrk1b
Name: dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
Synonyms: Mirk
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 13549
HGNC: HGNC:3092
Homologene: 31253
Olfr1419
Name: olfactory receptor 1419
Synonyms: MOR266-10, GA_x6K02T2RE5P-2222521-2221490
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 257938
Homologene: 79473
Galnt15
Name: polypeptide N-acetylgalactosaminyltransferase 15
Synonyms: Galntl2, 4631401E18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 78754
Homologene: 14286
Paxx
Name: non-homologous end joining factor
Synonyms: paralog of XRCC4 and XLF, BC029214, D930050G13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227622
Homologene: 17788
Tnnt3
Tmprss11d
Name: transmembrane protease, serine 11d
Synonyms: AsP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231382
Homologene: 74519
Fam170a
Name: family with sequence similarity 170, member A
Synonyms: Znfd, LOC225497
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 225497
VEGA: 18
Homologene: 86702
Pcdh1
Name: protocadherin 1
Synonyms: 2010005A06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 75599
HGNC: HGNC:8655
Homologene: 12613
Slc27a3
Name: solute carrier family 27 (fatty acid transporter), member 3
Synonyms: Acsvl3, FATP3, fatty acid transport protein 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 26568
Homologene: 11529
Klhl17
Name: kelch-like 17
Synonyms: actinfilin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 231003
VEGA: 4
Homologene: 27075
Mpped2
Name: metallophosphoesterase domain containing 2
Synonyms: 2700082O15Rik, 239Fb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 77015
HGNC: HGNC:1180
Homologene: 68190
Surf4
Name: surfeit gene 4
Synonyms: Surf-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20932
Homologene: 6052
Fam222a
Name: family with sequence similarity 222, member A
Synonyms: BC057022
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 433940
Homologene: 41895
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 44,166,993 bp
  • T to A, chromosome 1 at 45,823,359 bp
  • T to A, chromosome 1 at 136,503,407 bp
  • A to T, chromosome 1 at 170,668,864 bp
  • A to G, chromosome 2 at 9,952,184 bp
  • A to G, chromosome 2 at 25,460,649 bp
  • A to G, chromosome 2 at 26,933,766 bp
  • A to G, chromosome 2 at 106,699,502 bp
  • A to G, chromosome 2 at 120,333,403 bp
  • A to G, chromosome 2 at 122,327,922 bp
  • G to A, chromosome 2 at 181,515,086 bp
  • A to T, chromosome 3 at 90,389,219 bp
  • T to A, chromosome 3 at 95,128,289 bp
  • A to T, chromosome 3 at 100,617,012 bp
  • A to G, chromosome 4 at 98,111,225 bp
  • A to T, chromosome 4 at 123,475,945 bp
  • C to A, chromosome 4 at 156,230,527 bp
  • A to G, chromosome 5 at 32,830,247 bp
  • A to T, chromosome 5 at 38,320,023 bp
  • T to C, chromosome 5 at 62,683,489 bp
  • A to C, chromosome 5 at 86,309,355 bp
  • A to T, chromosome 5 at 112,338,272 bp
  • G to A, chromosome 5 at 114,611,066 bp
  • T to C, chromosome 6 at 35,205,284 bp
  • T to C, chromosome 6 at 55,968,006 bp
  • A to G, chromosome 6 at 73,195,732 bp
  • A to G, chromosome 7 at 25,916,994 bp
  • A to G, chromosome 7 at 28,185,096 bp
  • A to T, chromosome 7 at 28,916,255 bp
  • A to G, chromosome 7 at 86,811,638 bp
  • T to A, chromosome 7 at 142,514,372 bp
  • C to A, chromosome 8 at 47,065,451 bp
  • T to C, chromosome 9 at 21,389,383 bp
  • T to A, chromosome 9 at 110,851,475 bp
  • A to T, chromosome 10 at 81,367,528 bp
  • C to A, chromosome 11 at 21,997,037 bp
  • A to G, chromosome 11 at 53,698,820 bp
  • A to T, chromosome 11 at 68,783,195 bp
  • G to A, chromosome 11 at 73,110,556 bp
  • G to T, chromosome 13 at 49,296,378 bp
  • G to A, chromosome 14 at 32,049,865 bp
  • A to C, chromosome 14 at 50,868,110 bp
  • A to G, chromosome 14 at 75,584,009 bp
  • C to A, chromosome 15 at 82,062,544 bp
  • A to C, chromosome 16 at 13,401,592 bp
  • T to C, chromosome 16 at 18,952,115 bp
  • A to T, chromosome 17 at 21,992,813 bp
  • T to C, chromosome 17 at 79,865,151 bp
  • A to T, chromosome 18 at 38,198,918 bp
  • A to T, chromosome 18 at 50,282,126 bp
  • A to G, chromosome 18 at 65,476,055 bp
  • A to T, chromosome 19 at 11,870,631 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5201 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
042776-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.